Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Exocyst complex component EXO99

Species:

Leishmania major

UniProt:

Q4QC29_LEIMA

TriTrypDb:

LmjF.21.1569 , LMJLV39_210024800 , LMJSD75_210025000

Length:

931

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0000145	exocyst	3	2
GO:0005634	nucleus	5	2
GO:0005840	ribosome	5	11
GO:0020016	ciliary pocket	2	2
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	2
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	2

Previous1 2Next

Expansion

Sequence features

Q4QC29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC29

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	6
GO:0006364	rRNA processing	8	6
GO:0006396	RNA processing	6	6
GO:0006725	cellular aromatic compound metabolic process	3	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0006810	transport	3	2
GO:0006897	endocytosis	5	2
GO:0008152	metabolic process	1	6
GO:0009987	cellular process	1	6
GO:0016070	RNA metabolic process	5	6

Previous1 2 3Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	285	289	PF00656	0.494
CLV_NRD_NRD_1	19	21	PF00675	0.594
CLV_NRD_NRD_1	260	262	PF00675	0.560
CLV_NRD_NRD_1	405	407	PF00675	0.748
CLV_NRD_NRD_1	433	435	PF00675	0.514
CLV_NRD_NRD_1	447	449	PF00675	0.295
CLV_NRD_NRD_1	462	464	PF00675	0.338
CLV_NRD_NRD_1	613	615	PF00675	0.553
CLV_NRD_NRD_1	667	669	PF00675	0.532
CLV_NRD_NRD_1	762	764	PF00675	0.511

Previous1 2 3 4 5…26Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBU1	Leptomonas seymouri	72%	100%
A0A1X0NJ82	Trypanosomatidae	43%	100%
A0A3S7WWR2	Leishmania donovani	96%	100%
A0A422N8B4	Trypanosoma rangeli	42%	100%
A4HC13	Leishmania braziliensis	86%	100%
A4HZF4	Leishmania infantum	96%	100%
D0A113	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9AVF0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5B1W3	Trypanosoma cruzi	43%	100%

Previous1Next