LeishMANIAdb
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Zinc ribbon domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Zinc ribbon domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QC24_LEIMA
TriTrypDb:
LmjF.21.1605 , LMJLV39_210025400 * , LMJSD75_210025600 *
Length:
157

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 2
GO:0031974 membrane-enclosed lumen 2 2
GO:0031981 nuclear lumen 5 2
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 2
GO:0043233 organelle lumen 3 2
GO:0070013 intracellular organelle lumen 4 2
GO:0097014 ciliary plasm 5 2
GO:0099568 cytoplasmic region 3 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

Q4QC24
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC24

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 17 21 PF00656 0.514
CLV_C14_Caspase3-7 69 73 PF00656 0.729
CLV_NRD_NRD_1 103 105 PF00675 0.627
CLV_NRD_NRD_1 124 126 PF00675 0.619
CLV_PCSK_KEX2_1 126 128 PF00082 0.559
CLV_PCSK_PC1ET2_1 126 128 PF00082 0.599
DEG_Nend_UBRbox_3 1 3 PF02207 0.567
LIG_14-3-3_CanoR_1 37 42 PF00244 0.655
LIG_BRCT_BRCA1_1 131 135 PF00533 0.627
LIG_DLG_GKlike_1 37 44 PF00625 0.657
LIG_FHA_1 138 144 PF00498 0.687
LIG_FHA_1 56 62 PF00498 0.546
LIG_FHA_2 136 142 PF00498 0.682
LIG_FHA_2 15 21 PF00498 0.572
LIG_FHA_2 31 37 PF00498 0.647
LIG_Integrin_RGD_1 67 69 PF01839 0.512
LIG_LIR_Apic_2 103 109 PF02991 0.532
LIG_NRBOX 43 49 PF00104 0.545
LIG_SH3_3 136 142 PF00018 0.636
LIG_SUMO_SIM_anti_2 40 46 PF11976 0.646
LIG_TRAF2_1 33 36 PF00917 0.685
MOD_CK2_1 30 36 PF00069 0.706
MOD_GlcNHglycan 23 26 PF01048 0.748
MOD_GlcNHglycan 9 12 PF01048 0.639
MOD_GSK3_1 12 19 PF00069 0.581
MOD_GSK3_1 129 136 PF00069 0.625
MOD_GSK3_1 63 70 PF00069 0.676
MOD_NEK2_1 110 115 PF00069 0.516
MOD_NEK2_1 135 140 PF00069 0.598
MOD_NEK2_1 47 52 PF00069 0.576
MOD_NEK2_2 120 125 PF00069 0.596
MOD_PKA_2 100 106 PF00069 0.677
MOD_PKA_2 120 126 PF00069 0.368
MOD_Plk_2-3 146 152 PF00069 0.405
TRG_ER_diArg_1 124 127 PF00400 0.605
TRG_ER_diArg_1 79 82 PF00400 0.544
TRG_NLS_MonoExtC_3 124 130 PF00514 0.600

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P421 Leptomonas seymouri 43% 100%
A0A3Q8IE24 Leishmania donovani 87% 100%
A4HC22 Leishmania braziliensis 68% 100%
A4HZG5 Leishmania infantum 87% 100%
E9AVF5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS