Conjugal transfer protein TrbC

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBY4_LEIMA

TriTrypDb:

LmjF.22.0100 , LMJLV39_220006000 , LMJSD75_220006100

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBY4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBY4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	216	220	PF00656	0.600
CLV_NRD_NRD_1	176	178	PF00675	0.565
CLV_NRD_NRD_1	93	95	PF00675	0.624
CLV_PCSK_KEX2_1	176	178	PF00082	0.565
CLV_PCSK_KEX2_1	92	94	PF00082	0.640
CLV_PCSK_SKI1_1	153	157	PF00082	0.603
DEG_Nend_UBRbox_4	1	3	PF02207	0.669
DOC_MAPK_gen_1	176	182	PF00069	0.578
DOC_MAPK_gen_1	92	100	PF00069	0.643
DOC_PP2B_LxvP_1	233	236	PF13499	0.583
DOC_PP2B_LxvP_1	239	242	PF13499	0.544
DOC_PP2B_PxIxI_1	235	241	PF00149	0.585
DOC_PP4_FxxP_1	166	169	PF00568	0.671
DOC_USP7_MATH_1	3	7	PF00917	0.712
DOC_USP7_MATH_1	41	45	PF00917	0.556
DOC_USP7_MATH_1	8	12	PF00917	0.691
DOC_WW_Pin1_4	26	31	PF00397	0.753
DOC_WW_Pin1_4	43	48	PF00397	0.425
LIG_14-3-3_CanoR_1	125	129	PF00244	0.448
LIG_14-3-3_CanoR_1	176	181	PF00244	0.635
LIG_14-3-3_CanoR_1	210	218	PF00244	0.568
LIG_14-3-3_CanoR_1	32	38	PF00244	0.652
LIG_14-3-3_CanoR_1	40	50	PF00244	0.657
LIG_FHA_1	146	152	PF00498	0.685
LIG_FHA_1	157	163	PF00498	0.717
LIG_FHA_1	177	183	PF00498	0.374
LIG_FHA_1	228	234	PF00498	0.677
LIG_FHA_1	82	88	PF00498	0.670
LIG_LIR_Gen_1	127	135	PF02991	0.531
LIG_LIR_Nem_3	127	131	PF02991	0.496
LIG_LIR_Nem_3	199	205	PF02991	0.593
LIG_PCNA_yPIPBox_3	70	78	PF02747	0.627
LIG_SH2_CRK	18	22	PF00017	0.630
LIG_SH2_NCK_1	18	22	PF00017	0.630
LIG_SH2_STAP1	178	182	PF00017	0.598
LIG_SH2_STAP1	202	206	PF00017	0.538
LIG_SH2_STAT3	116	119	PF00017	0.640
LIG_SH2_STAT3	178	181	PF00017	0.672
LIG_SH2_STAT5	178	181	PF00017	0.659
LIG_SH2_STAT5	205	208	PF00017	0.549
LIG_SH3_3	46	52	PF00018	0.705
LIG_SUMO_SIM_anti_2	95	102	PF11976	0.634
LIG_TRAF2_2	117	122	PF00917	0.593
LIG_WRC_WIRS_1	197	202	PF05994	0.612
MOD_CDK_SPxK_1	26	32	PF00069	0.754
MOD_CK1_1	213	219	PF00069	0.631
MOD_CK1_1	31	37	PF00069	0.651
MOD_CK1_1	39	45	PF00069	0.631
MOD_CK2_1	3	9	PF00069	0.592
MOD_GlcNHglycan	215	218	PF01048	0.635
MOD_GSK3_1	145	152	PF00069	0.635
MOD_GSK3_1	196	203	PF00069	0.631
MOD_GSK3_1	3	10	PF00069	0.599
MOD_GSK3_1	36	43	PF00069	0.677
MOD_GSK3_1	81	88	PF00069	0.629
MOD_LATS_1	208	214	PF00433	0.637
MOD_N-GLC_1	157	162	PF02516	0.611
MOD_N-GLC_1	190	195	PF02516	0.612
MOD_NEK2_1	124	129	PF00069	0.508
MOD_NEK2_1	149	154	PF00069	0.726
MOD_NEK2_1	156	161	PF00069	0.706
MOD_NEK2_1	198	203	PF00069	0.570
MOD_NEK2_1	33	38	PF00069	0.622
MOD_NEK2_1	99	104	PF00069	0.570
MOD_NEK2_2	229	234	PF00069	0.685
MOD_PIKK_1	210	216	PF00454	0.640
MOD_PK_1	92	98	PF00069	0.681
MOD_PKA_1	176	182	PF00069	0.631
MOD_PKA_1	92	98	PF00069	0.648
MOD_PKA_2	124	130	PF00069	0.465
MOD_PKA_2	176	182	PF00069	0.631
MOD_PKA_2	31	37	PF00069	0.658
MOD_PKA_2	39	45	PF00069	0.642
MOD_PKA_2	92	98	PF00069	0.648
MOD_Plk_1	157	163	PF00069	0.613
MOD_Plk_1	190	196	PF00069	0.617
MOD_Plk_1	8	14	PF00069	0.597
MOD_Plk_2-3	145	151	PF00069	0.632
MOD_Plk_4	201	207	PF00069	0.560
MOD_Plk_4	229	235	PF00069	0.638
MOD_ProDKin_1	26	32	PF00069	0.754
MOD_ProDKin_1	43	49	PF00069	0.422
MOD_SUMO_for_1	79	82	PF00179	0.649
TRG_DiLeu_BaEn_2	72	78	PF01217	0.628
TRG_ER_diArg_1	175	177	PF00400	0.560
TRG_ER_diArg_1	92	94	PF00400	0.703
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.611

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZN5	Leptomonas seymouri	64%	100%
A0A1X0NTR1	Trypanosomatidae	39%	82%
A0A3Q8IC30	Leishmania donovani	96%	100%
A0A3R7LNK0	Trypanosoma rangeli	34%	89%
A4HC62	Leishmania braziliensis	76%	100%
C9ZSC5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	90%
E9AGZ0	Leishmania infantum	95%	100%
E9AVJ5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
V5BFS1	Trypanosoma cruzi	33%	86%