Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QBX2_LEIMA

TriTrypDb:

LmjF.22.0240 , LMJLV39_220007400 , LMJSD75_220007500

Length:

329

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBX2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBX2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	235	239	PF00656	0.598
CLV_MEL_PAP_1	101	107	PF00089	0.561
CLV_PCSK_KEX2_1	53	55	PF00082	0.678
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.694
CLV_PCSK_SKI1_1	309	313	PF00082	0.698
CLV_PCSK_SKI1_1	63	67	PF00082	0.705
DOC_ANK_TNKS_1	243	250	PF00023	0.685
DOC_CYCLIN_RxL_1	303	316	PF00134	0.690
DOC_CYCLIN_yCln2_LP_2	97	103	PF00134	0.655
DOC_PP1_RVXF_1	307	314	PF00149	0.694
DOC_USP7_MATH_1	108	112	PF00917	0.650
DOC_USP7_MATH_1	133	137	PF00917	0.586
DOC_USP7_MATH_1	231	235	PF00917	0.714
DOC_USP7_MATH_1	85	89	PF00917	0.653
DOC_USP7_UBL2_3	59	63	PF12436	0.776
DOC_WW_Pin1_4	129	134	PF00397	0.572
DOC_WW_Pin1_4	148	153	PF00397	0.603
DOC_WW_Pin1_4	174	179	PF00397	0.679
DOC_WW_Pin1_4	203	208	PF00397	0.693
DOC_WW_Pin1_4	268	273	PF00397	0.680
DOC_WW_Pin1_4	289	294	PF00397	0.680
DOC_WW_Pin1_4	46	51	PF00397	0.819
DOC_WW_Pin1_4	96	101	PF00397	0.654
LIG_14-3-3_CanoR_1	286	294	PF00244	0.691
LIG_14-3-3_CanoR_1	86	92	PF00244	0.814
LIG_14-3-3_CterR_2	325	329	PF00244	0.571
LIG_BIR_II_1	1	5	PF00653	0.712
LIG_BIR_III_2	316	320	PF00653	0.691
LIG_FHA_1	116	122	PF00498	0.650
LIG_FHA_1	149	155	PF00498	0.709
LIG_FHA_1	264	270	PF00498	0.667
LIG_FHA_1	68	74	PF00498	0.659
LIG_FHA_1	88	94	PF00498	0.817
LIG_FHA_2	170	176	PF00498	0.707
LIG_FHA_2	253	259	PF00498	0.685
LIG_FHA_2	263	269	PF00498	0.607
LIG_FHA_2	310	316	PF00498	0.638
LIG_FHA_2	38	44	PF00498	0.604
LIG_PDZ_Class_1	324	329	PF00595	0.594
LIG_SH3_3	201	207	PF00018	0.671
LIG_SH3_3	8	14	PF00018	0.712
LIG_SUMO_SIM_par_1	70	78	PF11976	0.631
LIG_SUMO_SIM_par_1	88	96	PF11976	0.698
LIG_TRAF2_1	5	8	PF00917	0.666
MOD_CDK_SPxxK_3	148	155	PF00069	0.595
MOD_CDK_SPxxK_3	46	53	PF00069	0.818
MOD_CK1_1	115	121	PF00069	0.682
MOD_CK1_1	129	135	PF00069	0.571
MOD_CK1_1	2	8	PF00069	0.653
MOD_CK1_1	206	212	PF00069	0.712
MOD_CK1_1	227	233	PF00069	0.683
MOD_CK1_1	285	291	PF00069	0.697
MOD_CK1_1	35	41	PF00069	0.674
MOD_CK2_1	150	156	PF00069	0.712
MOD_CK2_1	169	175	PF00069	0.578
MOD_CK2_1	2	8	PF00069	0.629
MOD_CK2_1	216	222	PF00069	0.630
MOD_CK2_1	250	256	PF00069	0.712
MOD_CK2_1	262	268	PF00069	0.592
MOD_GlcNHglycan	1	4	PF01048	0.672
MOD_GlcNHglycan	113	117	PF01048	0.641
MOD_GlcNHglycan	208	211	PF01048	0.666
MOD_GlcNHglycan	226	229	PF01048	0.529
MOD_GlcNHglycan	252	255	PF01048	0.603
MOD_GlcNHglycan	82	85	PF01048	0.769
MOD_GlcNHglycan	87	90	PF01048	0.721
MOD_GSK3_1	108	115	PF00069	0.647
MOD_GSK3_1	129	136	PF00069	0.600
MOD_GSK3_1	227	234	PF00069	0.684
MOD_GSK3_1	250	257	PF00069	0.669
MOD_GSK3_1	260	267	PF00069	0.660
MOD_GSK3_1	285	292	PF00069	0.801
MOD_GSK3_1	31	38	PF00069	0.699
MOD_GSK3_1	319	326	PF00069	0.668
MOD_GSK3_1	63	70	PF00069	0.643
MOD_N-GLC_2	279	281	PF02516	0.650
MOD_NEK2_1	160	165	PF00069	0.621
MOD_NEK2_1	211	216	PF00069	0.595
MOD_NEK2_1	31	36	PF00069	0.590
MOD_NEK2_1	321	326	PF00069	0.654
MOD_PIKK_1	13	19	PF00454	0.674
MOD_PIKK_1	160	166	PF00454	0.635
MOD_PIKK_1	216	222	PF00454	0.705
MOD_PKA_2	285	291	PF00069	0.810
MOD_PKA_2	85	91	PF00069	0.755
MOD_Plk_1	123	129	PF00069	0.652
MOD_Plk_1	31	37	PF00069	0.702
MOD_Plk_2-3	124	130	PF00069	0.559
MOD_Plk_2-3	39	45	PF00069	0.569
MOD_ProDKin_1	129	135	PF00069	0.574
MOD_ProDKin_1	148	154	PF00069	0.604
MOD_ProDKin_1	174	180	PF00069	0.682
MOD_ProDKin_1	203	209	PF00069	0.696
MOD_ProDKin_1	268	274	PF00069	0.678
MOD_ProDKin_1	289	295	PF00069	0.680
MOD_ProDKin_1	46	52	PF00069	0.818
MOD_ProDKin_1	96	102	PF00069	0.656
MOD_SUMO_rev_2	219	226	PF00179	0.640
TRG_DiLeu_BaEn_1	8	13	PF01217	0.652
TRG_DiLeu_BaLyEn_6	68	73	PF01217	0.561
TRG_Pf-PMV_PEXEL_1	196	200	PF00026	0.577

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7A5	Leishmania donovani	81%	100%
A4HC74	Leishmania braziliensis	52%	74%
A4HZQ1	Leishmania infantum	82%	100%
E9AVK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%