Condensin complex subunit 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBW5_LEIMA

TriTrypDb:

LmjF.22.0300 , LMJLV39_220008100 , LMJSD75_220008200

Length:

561

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	yes	yes: 4
Pissara et al.	no	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBW5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBW5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	122	124	PF00675	0.569
CLV_NRD_NRD_1	247	249	PF00675	0.586
CLV_NRD_NRD_1	411	413	PF00675	0.550
CLV_NRD_NRD_1	538	540	PF00675	0.830
CLV_PCSK_KEX2_1	413	415	PF00082	0.593
CLV_PCSK_KEX2_1	482	484	PF00082	0.539
CLV_PCSK_KEX2_1	504	506	PF00082	0.699
CLV_PCSK_KEX2_1	540	542	PF00082	0.796
CLV_PCSK_PC1ET2_1	413	415	PF00082	0.593
CLV_PCSK_PC1ET2_1	482	484	PF00082	0.563
CLV_PCSK_PC1ET2_1	504	506	PF00082	0.699
CLV_PCSK_PC1ET2_1	540	542	PF00082	0.796
CLV_PCSK_SKI1_1	124	128	PF00082	0.426
CLV_PCSK_SKI1_1	181	185	PF00082	0.578
CLV_PCSK_SKI1_1	205	209	PF00082	0.484
CLV_PCSK_SKI1_1	356	360	PF00082	0.411
CLV_PCSK_SKI1_1	363	367	PF00082	0.415
CLV_PCSK_SKI1_1	473	477	PF00082	0.479
DEG_APCC_DBOX_1	204	212	PF00400	0.517
DEG_APCC_DBOX_1	482	490	PF00400	0.620
DEG_SPOP_SBC_1	57	61	PF00917	0.645
DOC_CKS1_1	95	100	PF01111	0.567
DOC_CYCLIN_RxL_1	479	488	PF00134	0.606
DOC_MAPK_RevD_3	398	414	PF00069	0.515
DOC_PP1_RVXF_1	100	106	PF00149	0.419
DOC_PP1_RVXF_1	208	215	PF00149	0.417
DOC_PP1_RVXF_1	441	448	PF00149	0.532
DOC_PP4_MxPP_1	514	517	PF00568	0.776
DOC_USP7_MATH_1	192	196	PF00917	0.480
DOC_USP7_MATH_1	203	207	PF00917	0.436
DOC_USP7_MATH_1	452	456	PF00917	0.616
DOC_USP7_MATH_1	465	469	PF00917	0.597
DOC_USP7_MATH_1	91	95	PF00917	0.595
DOC_USP7_UBL2_3	6	10	PF12436	0.776
DOC_WW_Pin1_4	136	141	PF00397	0.499
DOC_WW_Pin1_4	9	14	PF00397	0.828
DOC_WW_Pin1_4	94	99	PF00397	0.538
LIG_14-3-3_CanoR_1	123	133	PF00244	0.552
LIG_14-3-3_CanoR_1	248	258	PF00244	0.604
LIG_14-3-3_CanoR_1	265	271	PF00244	0.323
LIG_14-3-3_CanoR_1	280	287	PF00244	0.418
LIG_14-3-3_CanoR_1	320	330	PF00244	0.474
LIG_14-3-3_CanoR_1	379	385	PF00244	0.553
LIG_14-3-3_CanoR_1	389	398	PF00244	0.456
LIG_14-3-3_CanoR_1	412	419	PF00244	0.566
LIG_BIR_II_1	1	5	PF00653	0.683
LIG_BIR_III_2	182	186	PF00653	0.615
LIG_BRCT_BRCA1_1	200	204	PF00533	0.524
LIG_BRCT_BRCA1_1	324	328	PF00533	0.587
LIG_Clathr_ClatBox_1	397	401	PF01394	0.507
LIG_FHA_1	125	131	PF00498	0.431
LIG_FHA_1	137	143	PF00498	0.454
LIG_FHA_1	237	243	PF00498	0.558
LIG_FHA_1	26	32	PF00498	0.718
LIG_FHA_1	267	273	PF00498	0.508
LIG_FHA_1	280	286	PF00498	0.483
LIG_FHA_1	301	307	PF00498	0.451
LIG_FHA_1	352	358	PF00498	0.478
LIG_FHA_1	392	398	PF00498	0.524
LIG_FHA_1	492	498	PF00498	0.572
LIG_FHA_1	95	101	PF00498	0.510
LIG_FHA_2	16	22	PF00498	0.774
LIG_FHA_2	338	344	PF00498	0.518
LIG_FHA_2	472	478	PF00498	0.532
LIG_LIR_Apic_2	255	261	PF02991	0.570
LIG_LIR_Gen_1	160	171	PF02991	0.472
LIG_LIR_Gen_1	274	283	PF02991	0.424
LIG_LIR_Gen_1	61	71	PF02991	0.453
LIG_LIR_Nem_3	160	166	PF02991	0.495
LIG_LIR_Nem_3	201	207	PF02991	0.427
LIG_LIR_Nem_3	274	278	PF02991	0.424
LIG_LIR_Nem_3	371	377	PF02991	0.433
LIG_LIR_Nem_3	440	445	PF02991	0.584
LIG_LIR_Nem_3	61	67	PF02991	0.452
LIG_LRP6_Inhibitor_1	467	473	PF00058	0.579
LIG_LYPXL_S_1	373	377	PF13949	0.515
LIG_LYPXL_yS_3	374	377	PF13949	0.520
LIG_MYND_3	294	298	PF01753	0.527
LIG_NRBOX	207	213	PF00104	0.517
LIG_NRP_CendR_1	560	561	PF00754	0.801
LIG_PCNA_yPIPBox_3	117	126	PF02747	0.554
LIG_PCNA_yPIPBox_3	291	300	PF02747	0.547
LIG_RPA_C_Fungi	407	419	PF08784	0.573
LIG_SH2_CRK	378	382	PF00017	0.457
LIG_SH2_CRK	442	446	PF00017	0.590
LIG_SH2_CRK	64	68	PF00017	0.476
LIG_SH2_SRC	258	261	PF00017	0.565
LIG_SH2_STAT3	81	84	PF00017	0.546
LIG_SH2_STAT5	165	168	PF00017	0.423
LIG_SH2_STAT5	300	303	PF00017	0.507
LIG_SH2_STAT5	376	379	PF00017	0.523
LIG_SH2_STAT5	81	84	PF00017	0.540
LIG_SH3_3	29	35	PF00018	0.716
LIG_SH3_3	47	53	PF00018	0.718
LIG_SH3_3	512	518	PF00018	0.693
LIG_SUMO_SIM_anti_2	313	319	PF11976	0.418
LIG_SUMO_SIM_par_1	154	160	PF11976	0.546
LIG_SUMO_SIM_par_1	268	274	PF11976	0.472
LIG_SUMO_SIM_par_1	356	362	PF11976	0.542
LIG_SUMO_SIM_par_1	380	387	PF11976	0.501
LIG_SUMO_SIM_par_1	396	401	PF11976	0.476
LIG_SUMO_SIM_par_1	69	74	PF11976	0.462
LIG_TRAF2_1	14	17	PF00917	0.779
LIG_TRAF2_1	38	41	PF00917	0.756
MOD_CK1_1	195	201	PF00069	0.525
MOD_CK1_1	383	389	PF00069	0.575
MOD_CK1_1	430	436	PF00069	0.550
MOD_CK1_1	530	536	PF00069	0.643
MOD_CK1_1	69	75	PF00069	0.588
MOD_CK1_1	9	15	PF00069	0.769
MOD_CK1_1	94	100	PF00069	0.584
MOD_CK2_1	321	327	PF00069	0.500
MOD_CK2_1	471	477	PF00069	0.541
MOD_CK2_1	56	62	PF00069	0.559
MOD_Cter_Amidation	526	529	PF01082	0.762
MOD_Cter_Amidation	558	561	PF01082	0.810
MOD_GlcNHglycan	201	204	PF01048	0.531
MOD_GlcNHglycan	414	417	PF01048	0.565
MOD_GlcNHglycan	429	432	PF01048	0.464
MOD_GlcNHglycan	461	464	PF01048	0.551
MOD_GSK3_1	195	202	PF00069	0.438
MOD_GSK3_1	359	366	PF00069	0.417
MOD_GSK3_1	423	430	PF00069	0.541
MOD_GSK3_1	58	65	PF00069	0.575
MOD_N-GLC_1	427	432	PF02516	0.549
MOD_NEK2_1	125	130	PF00069	0.488
MOD_NEK2_1	199	204	PF00069	0.451
MOD_NEK2_1	321	326	PF00069	0.462
MOD_NEK2_1	359	364	PF00069	0.520
MOD_NEK2_1	388	393	PF00069	0.557
MOD_NEK2_1	427	432	PF00069	0.551
MOD_NEK2_2	15	20	PF00069	0.603
MOD_PIKK_1	243	249	PF00454	0.565
MOD_PIKK_1	252	258	PF00454	0.472
MOD_PIKK_1	530	536	PF00454	0.819
MOD_PIKK_1	545	551	PF00454	0.712
MOD_PIKK_1	62	68	PF00454	0.570
MOD_PKA_1	412	418	PF00069	0.569
MOD_PKA_1	528	534	PF00069	0.816
MOD_PKA_2	236	242	PF00069	0.529
MOD_PKA_2	279	285	PF00069	0.564
MOD_PKA_2	388	394	PF00069	0.550
MOD_PKA_2	552	558	PF00069	0.815
MOD_Plk_1	15	21	PF00069	0.608
MOD_Plk_1	252	258	PF00069	0.605
MOD_Plk_1	423	429	PF00069	0.569
MOD_Plk_4	125	131	PF00069	0.445
MOD_Plk_4	154	160	PF00069	0.537
MOD_Plk_4	380	386	PF00069	0.531
MOD_Plk_4	66	72	PF00069	0.514
MOD_ProDKin_1	136	142	PF00069	0.489
MOD_ProDKin_1	9	15	PF00069	0.828
MOD_ProDKin_1	94	100	PF00069	0.541
MOD_SUMO_rev_2	532	542	PF00179	0.835
TRG_DiLeu_BaEn_1	96	101	PF01217	0.504
TRG_DiLeu_BaLyEn_6	237	242	PF01217	0.504
TRG_DiLeu_BaLyEn_6	258	263	PF01217	0.558
TRG_DiLeu_BaLyEn_6	292	297	PF01217	0.444
TRG_ENDOCYTIC_2	374	377	PF00928	0.434
TRG_ENDOCYTIC_2	378	381	PF00928	0.436
TRG_ENDOCYTIC_2	442	445	PF00928	0.594
TRG_ENDOCYTIC_2	64	67	PF00928	0.471
TRG_ER_diArg_1	101	104	PF00400	0.399
TRG_NES_CRM1_1	260	274	PF08389	0.532
TRG_NES_CRM1_1	277	290	PF08389	0.400
TRG_NES_CRM1_1	62	74	PF08389	0.486
TRG_NLS_Bipartite_1	528	544	PF00514	0.801
TRG_NLS_MonoExtC_3	411	417	PF00514	0.564
TRG_NLS_MonoExtC_3	539	545	PF00514	0.780
TRG_NLS_MonoExtN_4	3	8	PF00514	0.668
TRG_NLS_MonoExtN_4	537	544	PF00514	0.767

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4V0	Leptomonas seymouri	65%	95%
A0A0S4JSH7	Bodo saltans	29%	100%
A0A1X0NTF0	Trypanosomatidae	40%	99%
A0A3Q8IC40	Leishmania donovani	95%	100%
A0A3R7NVM0	Trypanosoma rangeli	42%	100%
A4HC80	Leishmania braziliensis	84%	100%
A4HZQ8	Leishmania infantum	95%	100%
C9ZSF1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9AVL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5BFQ6	Trypanosoma cruzi	41%	100%