UV radiation resistance-associated protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QBW0_LEIMA

TriTrypDb:

LmjF.22.0350 , LMJLV39_220008700 , LMJSD75_220008800

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBW0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBW0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	87	89	PF00675	0.675
CLV_NRD_NRD_1	93	95	PF00675	0.562
CLV_PCSK_KEX2_1	137	139	PF00082	0.531
CLV_PCSK_KEX2_1	87	89	PF00082	0.669
CLV_PCSK_KEX2_1	95	97	PF00082	0.521
CLV_PCSK_PC1ET2_1	137	139	PF00082	0.531
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.459
CLV_PCSK_SKI1_1	137	141	PF00082	0.590
CLV_PCSK_SKI1_1	235	239	PF00082	0.387
DEG_APCC_DBOX_1	93	101	PF00400	0.619
DEG_Nend_UBRbox_2	1	3	PF02207	0.616
DOC_MAPK_gen_1	168	177	PF00069	0.425
DOC_MAPK_gen_1	64	72	PF00069	0.513
DOC_MAPK_MEF2A_6	66	74	PF00069	0.439
DOC_PP1_RVXF_1	233	240	PF00149	0.429
DOC_PP2B_LxvP_1	176	179	PF13499	0.350
DOC_USP7_MATH_1	207	211	PF00917	0.399
LIG_14-3-3_CanoR_1	110	115	PF00244	0.616
LIG_14-3-3_CanoR_1	138	146	PF00244	0.529
LIG_14-3-3_CanoR_1	43	51	PF00244	0.486
LIG_14-3-3_CanoR_1	94	104	PF00244	0.616
LIG_BRCT_BRCA1_1	235	239	PF00533	0.435
LIG_FHA_1	190	196	PF00498	0.552
LIG_FHA_1	99	105	PF00498	0.448
LIG_FHA_2	114	120	PF00498	0.574
LIG_FHA_2	228	234	PF00498	0.422
LIG_NRBOX	171	177	PF00104	0.418
LIG_SH2_CRK	160	164	PF00017	0.564
LIG_SH2_STAP1	191	195	PF00017	0.521
LIG_SH2_STAT3	60	63	PF00017	0.468
LIG_SH2_STAT5	191	194	PF00017	0.516
LIG_SH2_STAT5	60	63	PF00017	0.468
LIG_SH3_3	201	207	PF00018	0.584
LIG_WRC_WIRS_1	20	25	PF05994	0.525
MOD_CK1_1	113	119	PF00069	0.559
MOD_CK1_1	210	216	PF00069	0.566
MOD_CK1_1	3	9	PF00069	0.675
MOD_CK1_1	98	104	PF00069	0.469
MOD_CK2_1	113	119	PF00069	0.563
MOD_CK2_1	196	202	PF00069	0.459
MOD_Cter_Amidation	135	138	PF01082	0.528
MOD_GlcNHglycan	10	13	PF01048	0.494
MOD_GlcNHglycan	2	5	PF01048	0.668
MOD_GSK3_1	145	152	PF00069	0.523
MOD_GSK3_1	76	83	PF00069	0.537
MOD_NEK2_1	159	164	PF00069	0.425
MOD_PIKK_1	113	119	PF00454	0.547
MOD_PIKK_1	76	82	PF00454	0.523
MOD_PKA_1	137	143	PF00069	0.530
MOD_PKA_1	95	101	PF00069	0.507
MOD_PKA_2	137	143	PF00069	0.530
MOD_PKA_2	170	176	PF00069	0.515
MOD_PKA_2	95	101	PF00069	0.519
MOD_Plk_1	196	202	PF00069	0.459
MOD_Plk_2-3	196	202	PF00069	0.459
MOD_Plk_4	19	25	PF00069	0.539
MOD_Plk_4	56	62	PF00069	0.468
MOD_SUMO_rev_2	89	97	PF00179	0.391
TRG_DiLeu_BaEn_3	18	24	PF01217	0.492
TRG_DiLeu_BaLyEn_6	179	184	PF01217	0.450
TRG_ENDOCYTIC_2	160	163	PF00928	0.483
TRG_ER_diArg_1	94	97	PF00400	0.637
TRG_Pf-PMV_PEXEL_1	182	186	PF00026	0.448
TRG_Pf-PMV_PEXEL_1	198	202	PF00026	0.433
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJI0	Leptomonas seymouri	26%	100%
A0A3Q8IE58	Leishmania donovani	86%	100%
A4HC84	Leishmania braziliensis	58%	100%
A4HZR3	Leishmania infantum	86%	100%
E9AVL9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%