LeishMANIAdb
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DUF402 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF402 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QBS9_LEIMA
TriTrypDb:
LmjF.22.0680 , LMJLV39_220011900 , LMJSD75_220012000
Length:
99

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBS9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBS9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 93 95 PF00675 0.641
CLV_PCSK_KEX2_1 93 95 PF00082 0.664
CLV_PCSK_SKI1_1 93 97 PF00082 0.579
DEG_Nend_Nbox_1 1 3 PF02207 0.433
DOC_CKS1_1 84 89 PF01111 0.428
DOC_MAPK_MEF2A_6 15 23 PF00069 0.363
DOC_PP4_FxxP_1 95 98 PF00568 0.491
DOC_WW_Pin1_4 15 20 PF00397 0.466
DOC_WW_Pin1_4 83 88 PF00397 0.651
LIG_14-3-3_CanoR_1 33 37 PF00244 0.432
LIG_EVH1_1 84 88 PF00568 0.513
LIG_LIR_Apic_2 65 69 PF02991 0.512
LIG_LIR_Gen_1 54 63 PF02991 0.587
LIG_LIR_Gen_1 78 89 PF02991 0.464
LIG_LIR_Nem_3 42 46 PF02991 0.413
LIG_LIR_Nem_3 78 84 PF02991 0.497
LIG_LIR_Nem_3 86 92 PF02991 0.490
LIG_LYPXL_yS_3 43 46 PF13949 0.394
LIG_MYND_1 44 48 PF01753 0.418
LIG_SH2_CRK 66 70 PF00017 0.566
LIG_SH2_NCK_1 66 70 PF00017 0.570
LIG_SH2_SRC 66 69 PF00017 0.570
LIG_SH2_STAT5 24 27 PF00017 0.381
LIG_SH2_STAT5 62 65 PF00017 0.542
LIG_SH3_1 24 30 PF00018 0.415
LIG_SH3_3 10 16 PF00018 0.408
LIG_SH3_3 24 30 PF00018 0.515
LIG_SH3_3 31 37 PF00018 0.403
LIG_SH3_3 45 51 PF00018 0.417
LIG_SH3_3 82 88 PF00018 0.465
LIG_TRAF2_1 51 54 PF00917 0.400
LIG_TRAF2_1 80 83 PF00917 0.504
LIG_TRFH_1 23 27 PF08558 0.378
MOD_CK2_1 69 75 PF00069 0.572
MOD_GlcNHglycan 75 78 PF01048 0.517
MOD_GSK3_1 69 76 PF00069 0.663
MOD_NEK2_2 69 74 PF00069 0.489
MOD_PKA_2 32 38 PF00069 0.564
MOD_ProDKin_1 15 21 PF00069 0.462
MOD_ProDKin_1 83 89 PF00069 0.655
TRG_DiLeu_BaEn_1 42 47 PF01217 0.398
TRG_ENDOCYTIC_2 43 46 PF00928 0.362
TRG_ER_diArg_1 92 94 PF00400 0.597

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4J0V0 Bodo saltans 39% 67%
A0A3S5IR05 Trypanosoma rangeli 47% 85%
A0A3S7WX29 Leishmania donovani 99% 100%
A4HCB3 Leishmania braziliensis 91% 94%
A4HZU5 Leishmania infantum 99% 100%
C9ZSF5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 73%
E9AVQ0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS