Zinc_finger_protein_-_putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBS3_LEIMA

TriTrypDb:

LmjF.22.0740 , LMJLV39_220012900 , LMJSD75_220013000

Length:

590

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QBS3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBS3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	83	87	PF00656	0.461
CLV_NRD_NRD_1	173	175	PF00675	0.371
CLV_NRD_NRD_1	287	289	PF00675	0.624
CLV_NRD_NRD_1	29	31	PF00675	0.356
CLV_NRD_NRD_1	62	64	PF00675	0.423
CLV_PCSK_KEX2_1	173	175	PF00082	0.371
CLV_PCSK_KEX2_1	287	289	PF00082	0.624
CLV_PCSK_SKI1_1	173	177	PF00082	0.401
CLV_PCSK_SKI1_1	180	184	PF00082	0.428
CLV_PCSK_SKI1_1	235	239	PF00082	0.370
CLV_PCSK_SKI1_1	287	291	PF00082	0.601
CLV_PCSK_SKI1_1	30	34	PF00082	0.347
CLV_PCSK_SKI1_1	535	539	PF00082	0.593
DEG_APCC_DBOX_1	46	54	PF00400	0.420
DEG_SPOP_SBC_1	267	271	PF00917	0.628
DEG_SPOP_SBC_1	431	435	PF00917	0.509
DEG_SPOP_SBC_1	492	496	PF00917	0.685
DOC_CKS1_1	182	187	PF01111	0.401
DOC_CKS1_1	301	306	PF01111	0.507
DOC_CYCLIN_RxL_1	27	36	PF00134	0.416
DOC_MAPK_gen_1	481	491	PF00069	0.590
DOC_MAPK_MEF2A_6	481	489	PF00069	0.646
DOC_PP2B_LxvP_1	148	151	PF13499	0.389
DOC_PP2B_LxvP_1	32	35	PF13499	0.338
DOC_PP2B_LxvP_1	396	399	PF13499	0.581
DOC_PP2B_LxvP_1	489	492	PF13499	0.637
DOC_USP7_MATH_1	136	140	PF00917	0.539
DOC_USP7_MATH_1	151	155	PF00917	0.433
DOC_USP7_MATH_1	206	210	PF00917	0.441
DOC_USP7_MATH_1	353	357	PF00917	0.608
DOC_USP7_MATH_1	369	373	PF00917	0.710
DOC_USP7_MATH_1	376	380	PF00917	0.709
DOC_USP7_MATH_1	388	392	PF00917	0.477
DOC_USP7_MATH_1	460	464	PF00917	0.657
DOC_USP7_MATH_1	492	496	PF00917	0.605
DOC_USP7_MATH_1	520	524	PF00917	0.752
DOC_WW_Pin1_4	181	186	PF00397	0.383
DOC_WW_Pin1_4	244	249	PF00397	0.569
DOC_WW_Pin1_4	300	305	PF00397	0.681
DOC_WW_Pin1_4	466	471	PF00397	0.575
DOC_WW_Pin1_4	475	480	PF00397	0.588
DOC_WW_Pin1_4	514	519	PF00397	0.619
LIG_14-3-3_CanoR_1	10	15	PF00244	0.396
LIG_14-3-3_CanoR_1	165	171	PF00244	0.345
LIG_14-3-3_CanoR_1	189	193	PF00244	0.464
LIG_14-3-3_CanoR_1	309	313	PF00244	0.628
LIG_14-3-3_CanoR_1	484	490	PF00244	0.590
LIG_14-3-3_CanoR_1	80	89	PF00244	0.493
LIG_Actin_WH2_2	97	112	PF00022	0.515
LIG_FHA_1	167	173	PF00498	0.349
LIG_FHA_1	185	191	PF00498	0.437
LIG_FHA_1	248	254	PF00498	0.669
LIG_FHA_1	269	275	PF00498	0.639
LIG_FHA_1	27	33	PF00498	0.365
LIG_FHA_1	34	40	PF00498	0.361
LIG_FHA_1	431	437	PF00498	0.655
LIG_FHA_1	495	501	PF00498	0.640
LIG_FHA_2	21	27	PF00498	0.391
LIG_FHA_2	236	242	PF00498	0.496
LIG_FHA_2	92	98	PF00498	0.450
LIG_IBAR_NPY_1	552	554	PF08397	0.558
LIG_LIR_Apic_2	579	585	PF02991	0.568
LIG_LIR_Gen_1	227	237	PF02991	0.343
LIG_LIR_Gen_1	311	318	PF02991	0.627
LIG_LIR_Gen_1	74	81	PF02991	0.417
LIG_LIR_Nem_3	157	163	PF02991	0.397
LIG_LIR_Nem_3	227	233	PF02991	0.389
LIG_LIR_Nem_3	311	316	PF02991	0.571
LIG_LIR_Nem_3	579	584	PF02991	0.547
LIG_LIR_Nem_3	74	78	PF02991	0.408
LIG_NRBOX	171	177	PF00104	0.365
LIG_SH2_CRK	582	586	PF00017	0.568
LIG_SH2_SRC	149	152	PF00017	0.412
LIG_SH2_STAT5	149	152	PF00017	0.379
LIG_SH2_STAT5	168	171	PF00017	0.260
LIG_SH2_STAT5	38	41	PF00017	0.439
LIG_SH2_STAT5	383	386	PF00017	0.638
LIG_SH2_STAT5	419	422	PF00017	0.675
LIG_SH2_STAT5	554	557	PF00017	0.620
LIG_SH3_2	304	309	PF14604	0.564
LIG_SH3_3	21	27	PF00018	0.333
LIG_SH3_3	301	307	PF00018	0.567
LIG_SH3_3	362	368	PF00018	0.665
LIG_SH3_3	434	440	PF00018	0.641
LIG_TRFH_1	475	479	PF08558	0.533
MOD_CDC14_SPxK_1	478	481	PF00782	0.515
MOD_CDK_SPxK_1	475	481	PF00069	0.569
MOD_CK1_1	209	215	PF00069	0.530
MOD_CK1_1	247	253	PF00069	0.689
MOD_CK1_1	268	274	PF00069	0.652
MOD_CK1_1	282	288	PF00069	0.572
MOD_CK1_1	311	317	PF00069	0.606
MOD_CK1_1	372	378	PF00069	0.786
MOD_CK1_1	455	461	PF00069	0.589
MOD_CK1_1	468	474	PF00069	0.591
MOD_CK1_1	495	501	PF00069	0.562
MOD_CK1_1	509	515	PF00069	0.612
MOD_CK1_1	529	535	PF00069	0.725
MOD_CK1_1	543	549	PF00069	0.569
MOD_CK2_1	151	157	PF00069	0.467
MOD_GlcNHglycan	129	132	PF01048	0.651
MOD_GlcNHglycan	207	211	PF01048	0.511
MOD_GlcNHglycan	297	300	PF01048	0.792
MOD_GlcNHglycan	374	377	PF01048	0.621
MOD_GlcNHglycan	386	389	PF01048	0.525
MOD_GlcNHglycan	392	395	PF01048	0.486
MOD_GlcNHglycan	414	417	PF01048	0.637
MOD_GlcNHglycan	444	447	PF01048	0.607
MOD_GlcNHglycan	470	473	PF01048	0.639
MOD_GlcNHglycan	497	500	PF01048	0.498
MOD_GlcNHglycan	567	570	PF01048	0.549
MOD_GlcNHglycan	58	61	PF01048	0.400
MOD_GSK3_1	123	130	PF00069	0.505
MOD_GSK3_1	184	191	PF00069	0.481
MOD_GSK3_1	261	268	PF00069	0.629
MOD_GSK3_1	275	282	PF00069	0.562
MOD_GSK3_1	289	296	PF00069	0.532
MOD_GSK3_1	308	315	PF00069	0.579
MOD_GSK3_1	347	354	PF00069	0.750
MOD_GSK3_1	372	379	PF00069	0.790
MOD_GSK3_1	384	391	PF00069	0.568
MOD_GSK3_1	455	462	PF00069	0.782
MOD_GSK3_1	487	494	PF00069	0.686
MOD_GSK3_1	505	512	PF00069	0.550
MOD_GSK3_1	520	527	PF00069	0.567
MOD_GSK3_1	529	536	PF00069	0.668
MOD_GSK3_1	540	547	PF00069	0.595
MOD_GSK3_1	554	561	PF00069	0.631
MOD_GSK3_1	80	87	PF00069	0.521
MOD_N-GLC_1	275	280	PF02516	0.629
MOD_N-GLC_1	452	457	PF02516	0.782
MOD_N-GLC_1	465	470	PF02516	0.573
MOD_N-GLC_1	509	514	PF02516	0.644
MOD_N-GLC_1	544	549	PF02516	0.518
MOD_NEK2_1	109	114	PF00069	0.591
MOD_NEK2_1	156	161	PF00069	0.502
MOD_NEK2_1	20	25	PF00069	0.547
MOD_NEK2_1	265	270	PF00069	0.589
MOD_NEK2_1	289	294	PF00069	0.760
MOD_NEK2_1	347	352	PF00069	0.508
MOD_NEK2_1	384	389	PF00069	0.586
MOD_NEK2_1	420	425	PF00069	0.629
MOD_NEK2_1	452	457	PF00069	0.572
MOD_NEK2_1	506	511	PF00069	0.587
MOD_NEK2_1	524	529	PF00069	0.765
MOD_NEK2_1	533	538	PF00069	0.485
MOD_NEK2_1	540	545	PF00069	0.596
MOD_NEK2_1	56	61	PF00069	0.392
MOD_NEK2_2	151	156	PF00069	0.433
MOD_PIKK_1	33	39	PF00454	0.417
MOD_PIKK_1	351	357	PF00454	0.553
MOD_PIKK_1	460	466	PF00454	0.541
MOD_PIKK_1	535	541	PF00454	0.594
MOD_PIKK_1	80	86	PF00454	0.459
MOD_PKA_2	109	115	PF00069	0.574
MOD_PKA_2	164	170	PF00069	0.346
MOD_PKA_2	188	194	PF00069	0.464
MOD_PKA_2	308	314	PF00069	0.626
MOD_PKA_2	376	382	PF00069	0.597
MOD_PKA_2	46	52	PF00069	0.376
MOD_PKA_2	485	491	PF00069	0.639
MOD_Plk_1	137	143	PF00069	0.583
MOD_Plk_1	278	284	PF00069	0.615
MOD_Plk_1	544	550	PF00069	0.516
MOD_Plk_4	151	157	PF00069	0.436
MOD_Plk_4	20	26	PF00069	0.354
MOD_Plk_4	308	314	PF00069	0.568
MOD_Plk_4	338	344	PF00069	0.563
MOD_Plk_4	361	367	PF00069	0.639
MOD_ProDKin_1	181	187	PF00069	0.388
MOD_ProDKin_1	244	250	PF00069	0.580
MOD_ProDKin_1	300	306	PF00069	0.680
MOD_ProDKin_1	466	472	PF00069	0.578
MOD_ProDKin_1	475	481	PF00069	0.586
MOD_ProDKin_1	514	520	PF00069	0.619
MOD_SUMO_for_1	559	562	PF00179	0.563
MOD_SUMO_rev_2	226	231	PF00179	0.422
TRG_DiLeu_BaEn_1	178	183	PF01217	0.361
TRG_DiLeu_BaEn_1	392	397	PF01217	0.641
TRG_DiLeu_BaEn_2	225	231	PF01217	0.354
TRG_DiLeu_BaEn_4	226	232	PF01217	0.406
TRG_DiLeu_BaLyEn_6	171	176	PF01217	0.357
TRG_DiLeu_LyEn_5	392	397	PF01217	0.641
TRG_ENDOCYTIC_2	160	163	PF00928	0.374
TRG_ER_diArg_1	172	174	PF00400	0.368
TRG_ER_diArg_1	221	224	PF00400	0.429
TRG_ER_diArg_1	287	289	PF00400	0.604
TRG_ER_diArg_1	484	487	PF00400	0.575
TRG_Pf-PMV_PEXEL_1	173	177	PF00026	0.377
TRG_Pf-PMV_PEXEL_1	395	400	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	439	444	PF00026	0.602

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6L3	Leptomonas seymouri	49%	100%
A0A1X0NUQ6	Trypanosomatidae	32%	100%
A0A3S7WX90	Leishmania donovani	93%	100%
A4HCC9	Leishmania braziliensis	80%	100%
E9AVQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%