Zinc_ribbon_16 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBR7_LEIMA

TriTrypDb:

LmjF.22.0800 , LMJLV39_220013500 , LMJSD75_220013600

Length:

354

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBR7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	188	192	PF00656	0.736
CLV_PCSK_KEX2_1	30	32	PF00082	0.564
CLV_PCSK_KEX2_1	336	338	PF00082	0.681
CLV_PCSK_KEX2_1	38	40	PF00082	0.464
CLV_PCSK_KEX2_1	9	11	PF00082	0.528
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.512
CLV_PCSK_PC1ET2_1	336	338	PF00082	0.681
CLV_PCSK_PC1ET2_1	38	40	PF00082	0.464
CLV_PCSK_PC1ET2_1	9	11	PF00082	0.511
CLV_PCSK_SKI1_1	38	42	PF00082	0.492
DOC_MAPK_gen_1	38	45	PF00069	0.478
DOC_MAPK_MEF2A_6	18	25	PF00069	0.465
DOC_MAPK_MEF2A_6	38	45	PF00069	0.428
DOC_MAPK_NFAT4_5	18	26	PF00069	0.473
DOC_PP1_RVXF_1	334	341	PF00149	0.682
DOC_PP2B_LxvP_1	297	300	PF13499	0.660
DOC_PP4_FxxP_1	25	28	PF00568	0.494
DOC_PP4_MxPP_1	140	143	PF00568	0.699
DOC_USP7_MATH_1	182	186	PF00917	0.797
DOC_USP7_MATH_1	237	241	PF00917	0.783
DOC_USP7_MATH_1	247	251	PF00917	0.554
DOC_USP7_MATH_1	257	261	PF00917	0.498
DOC_USP7_MATH_1	300	304	PF00917	0.675
DOC_USP7_MATH_1	306	310	PF00917	0.706
DOC_USP7_UBL2_3	88	92	PF12436	0.674
DOC_WW_Pin1_4	258	263	PF00397	0.745
DOC_WW_Pin1_4	302	307	PF00397	0.641
DOC_WW_Pin1_4	51	56	PF00397	0.533
LIG_14-3-3_CanoR_1	128	133	PF00244	0.543
LIG_14-3-3_CanoR_1	215	223	PF00244	0.753
LIG_14-3-3_CanoR_1	272	278	PF00244	0.553
LIG_14-3-3_CanoR_1	31	41	PF00244	0.551
LIG_BIR_II_1	1	5	PF00653	0.537
LIG_DLG_GKlike_1	128	135	PF00625	0.542
LIG_FHA_1	313	319	PF00498	0.696
LIG_FHA_1	348	354	PF00498	0.542
LIG_FHA_1	93	99	PF00498	0.626
LIG_FHA_2	281	287	PF00498	0.597
LIG_LIR_Gen_1	110	117	PF02991	0.507
LIG_LIR_Gen_1	131	140	PF02991	0.536
LIG_LIR_Nem_3	110	114	PF02991	0.512
LIG_LIR_Nem_3	131	136	PF02991	0.529
LIG_LIR_Nem_3	230	234	PF02991	0.671
LIG_NRBOX	19	25	PF00104	0.469
LIG_Pex14_2	111	115	PF04695	0.558
LIG_SH2_CRK	234	238	PF00017	0.668
LIG_SH2_STAP1	194	198	PF00017	0.661
LIG_SH2_STAT3	194	197	PF00017	0.665
LIG_SH3_2	87	92	PF14604	0.585
LIG_SH3_3	170	176	PF00018	0.742
LIG_SH3_3	221	227	PF00018	0.615
LIG_SH3_3	81	87	PF00018	0.494
LIG_SH3_3	99	105	PF00018	0.595
LIG_SUMO_SIM_anti_2	19	25	PF11976	0.469
LIG_SUMO_SIM_par_1	134	139	PF11976	0.537
LIG_SUMO_SIM_par_1	49	54	PF11976	0.519
LIG_TRAF2_1	185	188	PF00917	0.775
LIG_WRC_WIRS_1	127	132	PF05994	0.495
MOD_CK1_1	180	186	PF00069	0.687
MOD_CK1_1	214	220	PF00069	0.833
MOD_CK1_1	238	244	PF00069	0.782
MOD_CK1_1	258	264	PF00069	0.492
MOD_CK1_1	282	288	PF00069	0.704
MOD_CK1_1	302	308	PF00069	0.830
MOD_CK2_1	182	188	PF00069	0.628
MOD_CK2_1	302	308	PF00069	0.816
MOD_CK2_1	46	52	PF00069	0.656
MOD_GlcNHglycan	179	182	PF01048	0.676
MOD_GlcNHglycan	249	252	PF01048	0.670
MOD_GlcNHglycan	302	305	PF01048	0.796
MOD_GlcNHglycan	55	58	PF01048	0.539
MOD_GSK3_1	257	264	PF00069	0.796
MOD_GSK3_1	302	309	PF00069	0.715
MOD_N-GLC_1	166	171	PF02516	0.791
MOD_N-GLC_1	255	260	PF02516	0.778
MOD_NEK2_1	109	114	PF00069	0.548
MOD_NEK2_1	115	120	PF00069	0.529
MOD_NEK2_1	166	171	PF00069	0.690
MOD_NEK2_1	80	85	PF00069	0.477
MOD_PKA_2	214	220	PF00069	0.783
MOD_PKA_2	238	244	PF00069	0.682
MOD_Plk_4	227	233	PF00069	0.722
MOD_Plk_4	321	327	PF00069	0.606
MOD_Plk_4	80	86	PF00069	0.487
MOD_ProDKin_1	258	264	PF00069	0.742
MOD_ProDKin_1	302	308	PF00069	0.643
MOD_ProDKin_1	51	57	PF00069	0.531
MOD_SUMO_for_1	143	146	PF00179	0.765
MOD_SUMO_rev_2	214	223	PF00179	0.806
MOD_SUMO_rev_2	35	40	PF00179	0.482
TRG_DiLeu_BaLyEn_6	69	74	PF01217	0.455
TRG_ENDOCYTIC_2	294	297	PF00928	0.591
TRG_Pf-PMV_PEXEL_1	160	164	PF00026	0.732
TRG_Pf-PMV_PEXEL_1	196	200	PF00026	0.712
TRG_Pf-PMV_PEXEL_1	266	270	PF00026	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HZV2	Leishmania infantum	83%	100%