Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBP7_LEIMA

TriTrypDb:

LmjF.22.1000 , LMJLV39_220015500 , LMJSD75_220015700

Length:

586

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBP7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBP7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	308	312	PF00656	0.714
CLV_NRD_NRD_1	162	164	PF00675	0.735
CLV_NRD_NRD_1	317	319	PF00675	0.656
CLV_NRD_NRD_1	457	459	PF00675	0.717
CLV_PCSK_KEX2_1	162	164	PF00082	0.735
CLV_PCSK_KEX2_1	317	319	PF00082	0.691
CLV_PCSK_KEX2_1	457	459	PF00082	0.717
CLV_PCSK_SKI1_1	202	206	PF00082	0.723
CLV_PCSK_SKI1_1	317	321	PF00082	0.552
CLV_PCSK_SKI1_1	443	447	PF00082	0.451
DEG_SPOP_SBC_1	102	106	PF00917	0.635
DEG_SPOP_SBC_1	121	125	PF00917	0.499
DEG_SPOP_SBC_1	75	79	PF00917	0.646
DOC_CKS1_1	362	367	PF01111	0.640
DOC_CKS1_1	65	70	PF01111	0.712
DOC_CYCLIN_RxL_1	440	449	PF00134	0.447
DOC_MAPK_MEF2A_6	579	586	PF00069	0.601
DOC_PP2B_PxIxI_1	437	443	PF00149	0.517
DOC_PP4_FxxP_1	200	203	PF00568	0.693
DOC_SPAK_OSR1_1	579	583	PF12202	0.534
DOC_USP7_MATH_1	120	124	PF00917	0.727
DOC_USP7_MATH_1	164	168	PF00917	0.667
DOC_USP7_MATH_1	190	194	PF00917	0.575
DOC_USP7_MATH_1	270	274	PF00917	0.749
DOC_USP7_MATH_1	310	314	PF00917	0.585
DOC_USP7_MATH_1	410	414	PF00917	0.547
DOC_USP7_MATH_1	423	427	PF00917	0.635
DOC_USP7_MATH_1	436	440	PF00917	0.433
DOC_USP7_MATH_1	53	57	PF00917	0.733
DOC_USP7_MATH_1	76	80	PF00917	0.631
DOC_WW_Pin1_4	218	223	PF00397	0.583
DOC_WW_Pin1_4	266	271	PF00397	0.691
DOC_WW_Pin1_4	361	366	PF00397	0.656
DOC_WW_Pin1_4	42	47	PF00397	0.644
DOC_WW_Pin1_4	421	426	PF00397	0.696
DOC_WW_Pin1_4	428	433	PF00397	0.535
DOC_WW_Pin1_4	529	534	PF00397	0.455
DOC_WW_Pin1_4	64	69	PF00397	0.740
LIG_14-3-3_CanoR_1	196	204	PF00244	0.564
LIG_14-3-3_CanoR_1	292	298	PF00244	0.549
LIG_14-3-3_CanoR_1	358	363	PF00244	0.565
LIG_14-3-3_CanoR_1	483	489	PF00244	0.530
LIG_14-3-3_CanoR_1	507	516	PF00244	0.462
LIG_Actin_WH2_2	494	511	PF00022	0.455
LIG_BRCT_BRCA1_1	21	25	PF00533	0.627
LIG_BRCT_BRCA1_1	99	103	PF00533	0.601
LIG_CSL_BTD_1	533	536	PF09270	0.483
LIG_deltaCOP1_diTrp_1	6	12	PF00928	0.527
LIG_FHA_1	199	205	PF00498	0.531
LIG_FHA_1	361	367	PF00498	0.674
LIG_FHA_1	399	405	PF00498	0.577
LIG_FHA_1	439	445	PF00498	0.581
LIG_FHA_1	563	569	PF00498	0.446
LIG_FHA_2	131	137	PF00498	0.765
LIG_FHA_2	342	348	PF00498	0.401
LIG_HP1_1	324	328	PF01393	0.565
LIG_LIR_Apic_2	198	203	PF02991	0.683
LIG_LIR_Gen_1	153	164	PF02991	0.613
LIG_LIR_Gen_1	193	200	PF02991	0.629
LIG_LIR_Gen_1	22	32	PF02991	0.653
LIG_LIR_Gen_1	431	442	PF02991	0.454
LIG_LIR_Gen_1	558	568	PF02991	0.582
LIG_LIR_Nem_3	10	15	PF02991	0.529
LIG_LIR_Nem_3	153	159	PF02991	0.747
LIG_LIR_Nem_3	193	197	PF02991	0.635
LIG_LIR_Nem_3	22	28	PF02991	0.552
LIG_LIR_Nem_3	431	437	PF02991	0.467
LIG_LIR_Nem_3	487	493	PF02991	0.515
LIG_LIR_Nem_3	558	564	PF02991	0.452
LIG_MAD2	38	46	PF02301	0.727
LIG_PCNA_PIPBox_1	1	10	PF02747	0.515
LIG_PDZ_Class_2	581	586	PF00595	0.461
LIG_Pex14_1	8	12	PF04695	0.530
LIG_SH2_NCK_1	156	160	PF00017	0.586
LIG_SH2_NCK_1	546	550	PF00017	0.592
LIG_SH2_NCK_1	561	565	PF00017	0.376
LIG_SH2_PTP2	434	437	PF00017	0.454
LIG_SH2_STAP1	295	299	PF00017	0.634
LIG_SH2_STAT5	194	197	PF00017	0.578
LIG_SH2_STAT5	295	298	PF00017	0.642
LIG_SH2_STAT5	434	437	PF00017	0.454
LIG_SH3_3	114	120	PF00018	0.557
LIG_SH3_3	180	186	PF00018	0.669
LIG_SH3_3	298	304	PF00018	0.621
LIG_SH3_3	323	329	PF00018	0.673
LIG_SH3_3	359	365	PF00018	0.573
LIG_SH3_3	370	376	PF00018	0.577
LIG_SH3_3	432	438	PF00018	0.461
LIG_SH3_3	45	51	PF00018	0.764
LIG_SH3_3	530	536	PF00018	0.465
LIG_SH3_3	62	68	PF00018	0.625
LIG_SUMO_SIM_par_1	341	348	PF11976	0.444
LIG_SUMO_SIM_par_1	443	449	PF11976	0.511
LIG_SUMO_SIM_par_1	527	532	PF11976	0.613
LIG_TRAF2_1	3	6	PF00917	0.563
LIG_TYR_ITIM	559	564	PF00017	0.597
MOD_CK1_1	123	129	PF00069	0.754
MOD_CK1_1	167	173	PF00069	0.686
MOD_CK1_1	209	215	PF00069	0.721
MOD_CK1_1	260	266	PF00069	0.540
MOD_CK1_1	360	366	PF00069	0.701
MOD_CK1_1	381	387	PF00069	0.615
MOD_CK1_1	413	419	PF00069	0.607
MOD_CK1_1	42	48	PF00069	0.650
MOD_CK1_1	424	430	PF00069	0.597
MOD_CK1_1	461	467	PF00069	0.595
MOD_CK1_1	511	517	PF00069	0.451
MOD_CK1_1	77	83	PF00069	0.511
MOD_CK2_1	130	136	PF00069	0.763
MOD_CK2_1	151	157	PF00069	0.573
MOD_CK2_1	272	278	PF00069	0.755
MOD_GlcNHglycan	125	128	PF01048	0.775
MOD_GlcNHglycan	145	148	PF01048	0.555
MOD_GlcNHglycan	237	240	PF01048	0.710
MOD_GlcNHglycan	259	262	PF01048	0.538
MOD_GlcNHglycan	307	310	PF01048	0.591
MOD_GlcNHglycan	392	395	PF01048	0.693
MOD_GlcNHglycan	415	418	PF01048	0.678
MOD_GlcNHglycan	426	429	PF01048	0.541
MOD_GlcNHglycan	462	466	PF01048	0.693
MOD_GlcNHglycan	469	473	PF01048	0.635
MOD_GlcNHglycan	510	513	PF01048	0.466
MOD_GlcNHglycan	9	12	PF01048	0.545
MOD_GSK3_1	122	129	PF00069	0.648
MOD_GSK3_1	165	172	PF00069	0.745
MOD_GSK3_1	198	205	PF00069	0.699
MOD_GSK3_1	209	216	PF00069	0.635
MOD_GSK3_1	253	260	PF00069	0.470
MOD_GSK3_1	266	273	PF00069	0.674
MOD_GSK3_1	341	348	PF00069	0.422
MOD_GSK3_1	357	364	PF00069	0.639
MOD_GSK3_1	378	385	PF00069	0.623
MOD_GSK3_1	408	415	PF00069	0.583
MOD_GSK3_1	424	431	PF00069	0.581
MOD_GSK3_1	479	486	PF00069	0.592
MOD_GSK3_1	560	567	PF00069	0.449
MOD_GSK3_1	97	104	PF00069	0.612
MOD_N-GLC_1	235	240	PF02516	0.712
MOD_N-GLC_1	271	276	PF02516	0.683
MOD_N-GLC_1	479	484	PF02516	0.630
MOD_NEK2_1	101	106	PF00069	0.640
MOD_NEK2_1	230	235	PF00069	0.550
MOD_NEK2_1	253	258	PF00069	0.487
MOD_NEK2_1	305	310	PF00069	0.705
MOD_NEK2_1	345	350	PF00069	0.474
MOD_NEK2_1	390	395	PF00069	0.544
MOD_NEK2_1	446	451	PF00069	0.453
MOD_NEK2_1	463	468	PF00069	0.582
MOD_NEK2_1	470	475	PF00069	0.607
MOD_NEK2_1	508	513	PF00069	0.465
MOD_NEK2_1	560	565	PF00069	0.459
MOD_NEK2_2	438	443	PF00069	0.451
MOD_NEK2_2	555	560	PF00069	0.423
MOD_PIKK_1	463	469	PF00454	0.723
MOD_PK_1	358	364	PF00069	0.571
MOD_PKA_2	121	127	PF00069	0.656
MOD_PKA_2	151	157	PF00069	0.713
MOD_PKA_2	195	201	PF00069	0.561
MOD_PKA_2	240	246	PF00069	0.518
MOD_PKA_2	253	259	PF00069	0.517
MOD_PKA_2	357	363	PF00069	0.552
MOD_PKA_2	508	514	PF00069	0.462
MOD_PKA_2	53	59	PF00069	0.649
MOD_Plk_1	230	236	PF00069	0.500
MOD_Plk_1	271	277	PF00069	0.684
MOD_Plk_1	381	387	PF00069	0.645
MOD_Plk_1	87	93	PF00069	0.503
MOD_Plk_4	151	157	PF00069	0.694
MOD_Plk_4	190	196	PF00069	0.655
MOD_Plk_4	345	351	PF00069	0.472
MOD_Plk_4	403	409	PF00069	0.654
MOD_Plk_4	451	457	PF00069	0.515
MOD_Plk_4	492	498	PF00069	0.448
MOD_Plk_4	511	517	PF00069	0.451
MOD_Plk_4	537	543	PF00069	0.452
MOD_Plk_4	555	561	PF00069	0.433
MOD_Plk_4	77	83	PF00069	0.598
MOD_ProDKin_1	218	224	PF00069	0.576
MOD_ProDKin_1	266	272	PF00069	0.695
MOD_ProDKin_1	361	367	PF00069	0.658
MOD_ProDKin_1	42	48	PF00069	0.647
MOD_ProDKin_1	421	427	PF00069	0.694
MOD_ProDKin_1	428	434	PF00069	0.522
MOD_ProDKin_1	529	535	PF00069	0.457
MOD_ProDKin_1	64	70	PF00069	0.739
TRG_DiLeu_BaLyEn_6	440	445	PF01217	0.582
TRG_ENDOCYTIC_2	156	159	PF00928	0.726
TRG_ENDOCYTIC_2	194	197	PF00928	0.637
TRG_ENDOCYTIC_2	434	437	PF00928	0.454
TRG_ENDOCYTIC_2	561	564	PF00928	0.580
TRG_ER_diArg_1	317	319	PF00400	0.586
TRG_ER_diArg_1	456	458	PF00400	0.709
TRG_ER_diArg_1	507	510	PF00400	0.608
TRG_NES_CRM1_1	492	504	PF08389	0.517
TRG_Pf-PMV_PEXEL_1	13	18	PF00026	0.507
TRG_Pf-PMV_PEXEL_1	443	448	PF00026	0.448

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDA8	Leptomonas seymouri	50%	100%
A0A3Q8IEA0	Leishmania donovani	91%	100%
A4HCC4	Leishmania braziliensis	75%	100%
A4HZX3	Leishmania infantum	91%	100%
E9AVT2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%