Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QBP5_LEIMA

TriTrypDb:

LmjF.22.1020 , LMJLV39_220015700 , LMJSD75_220015900

Length:

440

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBP5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBP5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	133	137	PF00656	0.633
CLV_C14_Caspase3-7	321	325	PF00656	0.576
CLV_C14_Caspase3-7	330	334	PF00656	0.516
CLV_C14_Caspase3-7	417	421	PF00656	0.561
CLV_NRD_NRD_1	124	126	PF00675	0.593
CLV_NRD_NRD_1	192	194	PF00675	0.572
CLV_NRD_NRD_1	284	286	PF00675	0.673
CLV_PCSK_FUR_1	119	123	PF00082	0.598
CLV_PCSK_KEX2_1	119	121	PF00082	0.600
CLV_PCSK_KEX2_1	122	124	PF00082	0.586
CLV_PCSK_KEX2_1	192	194	PF00082	0.572
CLV_PCSK_KEX2_1	284	286	PF00082	0.679
CLV_PCSK_PC7_1	119	125	PF00082	0.599
CLV_PCSK_SKI1_1	186	190	PF00082	0.625
CLV_PCSK_SKI1_1	2	6	PF00082	0.561
CLV_PCSK_SKI1_1	436	440	PF00082	0.503
CLV_PCSK_SKI1_1	56	60	PF00082	0.652
DEG_Nend_UBRbox_1	1	4	PF02207	0.565
DEG_SCF_FBW7_1	8	15	PF00400	0.575
DEG_SPOP_SBC_1	326	330	PF00917	0.714
DOC_CKS1_1	13	18	PF01111	0.567
DOC_CYCLIN_yClb3_PxF_3	126	134	PF00134	0.636
DOC_MAPK_gen_1	284	290	PF00069	0.540
DOC_MAPK_MEF2A_6	311	319	PF00069	0.544
DOC_PP2B_LxvP_1	135	138	PF13499	0.569
DOC_PP2B_LxvP_1	35	38	PF13499	0.569
DOC_PP2B_LxvP_1	66	69	PF13499	0.636
DOC_PP2B_LxvP_1	83	86	PF13499	0.541
DOC_USP7_MATH_1	164	168	PF00917	0.557
DOC_USP7_MATH_1	21	25	PF00917	0.627
DOC_USP7_MATH_1	307	311	PF00917	0.610
DOC_USP7_MATH_1	313	317	PF00917	0.527
DOC_USP7_MATH_1	326	330	PF00917	0.595
DOC_USP7_MATH_1	395	399	PF00917	0.563
DOC_USP7_MATH_1	87	91	PF00917	0.646
DOC_USP7_MATH_2	87	93	PF00917	0.575
DOC_WW_Pin1_4	104	109	PF00397	0.664
DOC_WW_Pin1_4	224	229	PF00397	0.744
DOC_WW_Pin1_4	230	235	PF00397	0.678
DOC_WW_Pin1_4	33	38	PF00397	0.672
DOC_WW_Pin1_4	363	368	PF00397	0.601
DOC_WW_Pin1_4	64	69	PF00397	0.644
DOC_WW_Pin1_4	8	13	PF00397	0.654
LIG_14-3-3_CanoR_1	111	115	PF00244	0.587
LIG_14-3-3_CanoR_1	193	203	PF00244	0.576
LIG_14-3-3_CanoR_1	289	295	PF00244	0.579
LIG_14-3-3_CanoR_1	56	61	PF00244	0.653
LIG_BRCT_BRCA1_1	94	98	PF00533	0.621
LIG_deltaCOP1_diTrp_1	346	351	PF00928	0.547
LIG_EVH1_2	127	131	PF00568	0.634
LIG_FHA_1	199	205	PF00498	0.621
LIG_FHA_1	253	259	PF00498	0.806
LIG_FHA_1	3	9	PF00498	0.567
LIG_FHA_1	356	362	PF00498	0.481
LIG_FHA_1	375	381	PF00498	0.511
LIG_FHA_1	39	45	PF00498	0.589
LIG_FHA_2	227	233	PF00498	0.637
LIG_IRF3_LxIS_1	112	117	PF10401	0.587
LIG_LIR_Apic_2	170	176	PF02991	0.720
LIG_LIR_Apic_2	79	85	PF02991	0.741
LIG_LIR_Nem_3	346	352	PF02991	0.637
LIG_NRBOX	404	410	PF00104	0.573
LIG_REV1ctd_RIR_1	186	197	PF16727	0.569
LIG_SH2_NCK_1	173	177	PF00017	0.733
LIG_SH2_SRC	173	176	PF00017	0.734
LIG_SH2_STAT5	82	85	PF00017	0.823
LIG_SH3_1	123	129	PF00018	0.586
LIG_SH3_3	123	129	PF00018	0.742
LIG_SH3_3	142	148	PF00018	0.498
LIG_SH3_3	260	266	PF00018	0.600
LIG_SH3_3	361	367	PF00018	0.594
LIG_SH3_3	421	427	PF00018	0.592
LIG_SH3_3	47	53	PF00018	0.686
LIG_SUMO_SIM_par_1	236	243	PF11976	0.633
LIG_SUMO_SIM_par_1	371	377	PF11976	0.452
LIG_SUMO_SIM_par_1	5	11	PF11976	0.574
LIG_TRAF2_1	318	321	PF00917	0.574
LIG_TRAF2_2	203	208	PF00917	0.566
MOD_CDK_SPxxK_3	104	111	PF00069	0.573
MOD_CDK_SPxxK_3	33	40	PF00069	0.577
MOD_CK1_1	166	172	PF00069	0.614
MOD_CK1_1	197	203	PF00069	0.564
MOD_CK1_1	23	29	PF00069	0.581
MOD_CK1_1	239	245	PF00069	0.707
MOD_CK1_1	3	9	PF00069	0.578
MOD_CK1_1	325	331	PF00069	0.598
MOD_CK1_1	334	340	PF00069	0.608
MOD_CK1_1	36	42	PF00069	0.545
MOD_CK1_1	418	424	PF00069	0.560
MOD_CK1_1	64	70	PF00069	0.745
MOD_CK1_1	92	98	PF00069	0.646
MOD_CK2_1	217	223	PF00069	0.709
MOD_CK2_1	226	232	PF00069	0.624
MOD_CK2_1	272	278	PF00069	0.584
MOD_CK2_1	315	321	PF00069	0.583
MOD_CK2_1	85	91	PF00069	0.567
MOD_GlcNHglycan	145	148	PF01048	0.781
MOD_GlcNHglycan	160	163	PF01048	0.641
MOD_GlcNHglycan	166	169	PF01048	0.673
MOD_GlcNHglycan	25	28	PF01048	0.622
MOD_GlcNHglycan	274	277	PF01048	0.585
MOD_GlcNHglycan	298	301	PF01048	0.785
MOD_GlcNHglycan	324	327	PF01048	0.559
MOD_GlcNHglycan	398	401	PF01048	0.585
MOD_GlcNHglycan	46	49	PF01048	0.729
MOD_GSK3_1	110	117	PF00069	0.653
MOD_GSK3_1	139	146	PF00069	0.624
MOD_GSK3_1	158	165	PF00069	0.496
MOD_GSK3_1	193	200	PF00069	0.660
MOD_GSK3_1	2	9	PF00069	0.665
MOD_GSK3_1	21	28	PF00069	0.588
MOD_GSK3_1	226	233	PF00069	0.772
MOD_GSK3_1	236	243	PF00069	0.665
MOD_GSK3_1	322	329	PF00069	0.738
MOD_GSK3_1	334	341	PF00069	0.555
MOD_GSK3_1	351	358	PF00069	0.541
MOD_GSK3_1	56	63	PF00069	0.716
MOD_GSK3_1	85	92	PF00069	0.690
MOD_N-GLC_1	224	229	PF02516	0.654
MOD_N-GLC_1	252	257	PF02516	0.673
MOD_N-GLC_1	296	301	PF02516	0.534
MOD_NEK2_1	114	119	PF00069	0.672
MOD_NEK2_1	143	148	PF00069	0.728
MOD_NEK2_1	238	243	PF00069	0.713
MOD_NEK2_1	288	293	PF00069	0.605
MOD_NEK2_1	31	36	PF00069	0.632
MOD_NEK2_1	4	9	PF00069	0.569
MOD_NEK2_1	44	49	PF00069	0.568
MOD_NEK2_1	54	59	PF00069	0.585
MOD_NEK2_1	60	65	PF00069	0.592
MOD_OFUCOSY	214	221	PF10250	0.558
MOD_OFUCOSY	287	292	PF10250	0.565
MOD_PIKK_1	181	187	PF00454	0.618
MOD_PIKK_1	247	253	PF00454	0.643
MOD_PKA_2	110	116	PF00069	0.588
MOD_PKA_2	288	294	PF00069	0.612
MOD_PKA_2	322	328	PF00069	0.576
MOD_PKA_2	418	424	PF00069	0.614
MOD_Plk_1	307	313	PF00069	0.551
MOD_Plk_4	254	260	PF00069	0.690
MOD_Plk_4	418	424	PF00069	0.614
MOD_ProDKin_1	104	110	PF00069	0.667
MOD_ProDKin_1	224	230	PF00069	0.747
MOD_ProDKin_1	33	39	PF00069	0.673
MOD_ProDKin_1	363	369	PF00069	0.607
MOD_ProDKin_1	64	70	PF00069	0.702
MOD_ProDKin_1	8	14	PF00069	0.653
MOD_SUMO_rev_2	341	345	PF00179	0.435
TRG_DiLeu_BaLyEn_6	404	409	PF01217	0.564
TRG_DiLeu_BaLyEn_6	433	438	PF01217	0.686
TRG_ER_diArg_1	119	122	PF00400	0.611
TRG_ER_diArg_1	123	125	PF00400	0.614
TRG_ER_diArg_1	283	285	PF00400	0.706
TRG_Pf-PMV_PEXEL_1	436	440	PF00026	0.568

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HCC2	Leishmania braziliensis	53%	100%
E9AVT4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	89%