Peptidyl-prolyl cis-trans isomerase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cyclophilin 6, putative

Species:

Leishmania major

UniProt:

Q4QBK2_LEIMA

TriTrypDb:

LmjF.22.1450 , LMJLV39_220020200 , LMJSD75_220020800

Length:

229

Annotations

LeishMANIAdb annotations

A large collection of conserved eukaryotic peptidyl-prolyl cis-trans isomerases. Some members of this group are secreted (into the ER).. Localization: Cytoplasmic (by homology) / ER (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QBK2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBK2

PDB structure(s): 7aih_BH , 7am2_BH , 7ane_BH

Function

Biological processes
Term	Name	Level	Count
GO:0000413	protein peptidyl-prolyl isomerization	7	11
GO:0006457	protein folding	2	7
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	7
GO:0018193	peptidyl-amino acid modification	5	11
GO:0018208	peptidyl-proline modification	6	11
GO:0019538	protein metabolic process	3	11
GO:0036211	protein modification process	4	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043412	macromolecule modification	4	11
GO:0044238	primary metabolic process	2	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11

Molecular functions
Term	Name	Level	Count
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3	11
GO:0003824	catalytic activity	1	11
GO:0005488	binding	1	2
GO:0016018	cyclosporin A binding	4	2
GO:0016853	isomerase activity	2	11
GO:0016859	cis-trans isomerase activity	3	11
GO:0033218	amide binding	2	2
GO:0042277	peptide binding	3	2
GO:0140096	catalytic activity, acting on a protein	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	153	155	PF00675	0.366
CLV_PCSK_SKI1_1	13	17	PF00082	0.480
CLV_PCSK_SKI1_1	219	223	PF00082	0.512
CLV_PCSK_SKI1_1	6	10	PF00082	0.626
DEG_Nend_Nbox_1	1	3	PF02207	0.563
DEG_SCF_FBW7_1	18	25	PF00400	0.400
DOC_CKS1_1	19	24	PF01111	0.491
DOC_CYCLIN_yCln2_LP_2	16	22	PF00134	0.504
DOC_MAPK_FxFP_2	107	110	PF00069	0.295
DOC_MAPK_gen_1	98	106	PF00069	0.295
DOC_PP2B_LxvP_1	16	19	PF13499	0.517
DOC_PP4_FxxP_1	107	110	PF00568	0.295
DOC_USP7_MATH_1	112	116	PF00917	0.272
DOC_USP7_MATH_1	53	57	PF00917	0.401
DOC_USP7_MATH_1	8	12	PF00917	0.665
DOC_WW_Pin1_4	179	184	PF00397	0.295
DOC_WW_Pin1_4	18	23	PF00397	0.485
DOC_WW_Pin1_4	76	81	PF00397	0.349
LIG_14-3-3_CanoR_1	101	107	PF00244	0.301
LIG_14-3-3_CanoR_1	42	46	PF00244	0.276
LIG_14-3-3_CanoR_1	54	62	PF00244	0.276
LIG_APCC_ABBA_1	45	50	PF00400	0.276
LIG_BIR_III_4	38	42	PF00653	0.284
LIG_BRCT_BRCA1_1	139	143	PF00533	0.276
LIG_BRCT_BRCA1_1	55	59	PF00533	0.401
LIG_FHA_1	23	29	PF00498	0.330
LIG_LIR_Apic_2	105	110	PF02991	0.313
LIG_LIR_Gen_1	153	163	PF02991	0.326
LIG_LIR_Gen_1	79	89	PF02991	0.330
LIG_LIR_Nem_3	140	146	PF02991	0.276
LIG_LIR_Nem_3	153	159	PF02991	0.276
LIG_LIR_Nem_3	46	51	PF02991	0.308
LIG_LIR_Nem_3	56	62	PF02991	0.238
LIG_LIR_Nem_3	79	84	PF02991	0.398
LIG_MLH1_MIPbox_1	139	143	PF16413	0.276
LIG_Pex14_2	107	111	PF04695	0.276
LIG_SH2_CRK	20	24	PF00017	0.491
LIG_SH2_NCK_1	20	24	PF00017	0.491
LIG_SH2_STAT5	20	23	PF00017	0.445
LIG_SH2_STAT5	30	33	PF00017	0.371
LIG_SH3_3	16	22	PF00018	0.467
LIG_SUMO_SIM_anti_2	220	226	PF11976	0.495
LIG_TYR_ITIM	28	33	PF00017	0.411
MOD_CDK_SPxxK_3	179	186	PF00069	0.295
MOD_CDK_SPxxK_3	76	83	PF00069	0.330
MOD_CK1_1	102	108	PF00069	0.361
MOD_CK1_1	61	67	PF00069	0.276
MOD_GlcNHglycan	132	135	PF01048	0.295
MOD_GlcNHglycan	194	197	PF01048	0.417
MOD_GSK3_1	175	182	PF00069	0.307
MOD_GSK3_1	18	25	PF00069	0.354
MOD_N-GLC_1	102	107	PF02516	0.276
MOD_N-GLC_1	137	142	PF02516	0.276
MOD_NEK2_1	130	135	PF00069	0.316
MOD_NEK2_1	175	180	PF00069	0.320
MOD_PIKK_1	137	143	PF00454	0.276
MOD_PIKK_1	200	206	PF00454	0.634
MOD_PKA_2	2	8	PF00069	0.531
MOD_PKA_2	41	47	PF00069	0.276
MOD_PKA_2	53	59	PF00069	0.276
MOD_Plk_1	102	108	PF00069	0.276
MOD_Plk_1	112	118	PF00069	0.276
MOD_Plk_4	102	108	PF00069	0.284
MOD_ProDKin_1	179	185	PF00069	0.295
MOD_ProDKin_1	18	24	PF00069	0.490
MOD_ProDKin_1	76	82	PF00069	0.349
MOD_SUMO_rev_2	113	120	PF00179	0.319
MOD_SUMO_rev_2	150	157	PF00179	0.288
TRG_DiLeu_BaEn_1	220	225	PF01217	0.538
TRG_ENDOCYTIC_2	20	23	PF00928	0.437
TRG_ENDOCYTIC_2	30	33	PF00928	0.354

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A075B759	Homo sapiens	45%	100%
A0A075B767	Homo sapiens	44%	100%
A0A0B4J2A2	Homo sapiens	45%	100%
A0A0N0P364	Leptomonas seymouri	86%	100%
A0A0N0P523	Leptomonas seymouri	46%	83%
A0A0N0P839	Leptomonas seymouri	46%	100%
A0A0N1I0P5	Leptomonas seymouri	49%	100%
A0A0N1I6E6	Leptomonas seymouri	40%	100%
A0A0N1I8P9	Leptomonas seymouri	42%	78%
A0A0N1IL84	Leptomonas seymouri	30%	72%
A0A0N1PC19	Leptomonas seymouri	31%	100%
A0A0N1PDY0	Leptomonas seymouri	32%	93%
A0A0S4IKA5	Bodo saltans	34%	75%
A0A0S4J0W0	Bodo saltans	45%	93%
A0A0S4J378	Bodo saltans	41%	100%
A0A0S4J465	Bodo saltans	27%	94%
A0A0S4J4A4	Bodo saltans	45%	100%
A0A0S4J7K8	Bodo saltans	50%	100%
A0A0S4J8W7	Bodo saltans	59%	99%
A0A0S4J9U9	Bodo saltans	32%	100%
A0A0S4KDV3	Bodo saltans	29%	100%
A0A0S4KGS8	Bodo saltans	37%	93%
A0A0S4KLH0	Bodo saltans	48%	100%
A0A1X0NJS0	Trypanosomatidae	42%	100%
A0A1X0NTQ9	Trypanosomatidae	44%	100%
A0A1X0NTS4	Trypanosomatidae	74%	99%
A0A1X0NXG7	Trypanosomatidae	50%	88%
A0A1X0P0F8	Trypanosomatidae	38%	67%
A0A1X0P184	Trypanosomatidae	48%	100%
A0A1X0P2K2	Trypanosomatidae	30%	87%
A0A1X0P4X3	Trypanosomatidae	33%	100%
A0A1X0P5F9	Trypanosomatidae	49%	100%
A0A3Q8ICB3	Leishmania donovani	99%	100%
A0A3Q8IDR1	Leishmania donovani	33%	80%
A0A3R7M7E5	Trypanosoma rangeli	29%	74%
A0A3R7MER6	Trypanosoma rangeli	36%	69%
A0A3R7MP70	Trypanosoma rangeli	31%	100%
A0A3R7NMR3	Trypanosoma rangeli	50%	100%
A0A3R7RC31	Trypanosoma rangeli	49%	100%
A0A3R7RE54	Trypanosoma rangeli	46%	89%
A0A3R7RI88	Trypanosoma rangeli	42%	100%
A0A3S5H5N2	Leishmania donovani	42%	100%
A0A3S5H7U6	Leishmania donovani	46%	89%
A0A3S5IQL2	Trypanosoma rangeli	31%	88%
A0A3S7WXF4	Leishmania donovani	48%	77%
A0A3S7WYY5	Leishmania donovani	50%	100%
A0A3S7X325	Leishmania donovani	33%	93%
A0A3S7X410	Leishmania donovani	45%	100%
A0A3S7XB52	Leishmania donovani	33%	86%
A0A422N1Z9	Trypanosoma rangeli	47%	100%
A0A422N490	Trypanosoma rangeli	74%	99%
A0A451EJ79	Leishmania donovani	29%	69%
A4FV72	Bos taurus	45%	76%
A4H346	Leishmania braziliensis	27%	68%
A4H4H8	Leishmania braziliensis	43%	100%
A4HCI8	Leishmania braziliensis	96%	100%
A4HCL8	Leishmania braziliensis	48%	77%
A4HE26	Leishmania braziliensis	51%	100%
A4HHU7	Leishmania braziliensis	33%	93%
A4HIW9	Leishmania braziliensis	47%	100%
A4HLM4	Leishmania braziliensis	47%	100%
A4HPH9	Leishmania braziliensis	36%	100%
A4HRE3	Leishmania infantum	29%	69%
A4HSQ3	Leishmania infantum	42%	100%
A4I004	Leishmania infantum	99%	100%
A4I042	Leishmania infantum	48%	77%
A4I1D2	Leishmania infantum	50%	100%
A4I4Z7	Leishmania infantum	33%	93%
A4I698	Leishmania infantum	45%	100%
A4I935	Leishmania infantum	46%	89%
A4IDA1	Leishmania infantum	33%	86%
A8X8D0	Caenorhabditis briggsae	38%	73%
B3A0R0	Lottia gigantea	41%	100%
C9ZIV0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
C9ZQE6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	88%
C9ZRQ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZSQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	69%	99%
C9ZT99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZUX8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	76%
C9ZVY5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	81%
D0A5M6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
D0A8E1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D4AY02	Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)	38%	100%
E9AC11	Leishmania major	29%	68%
E9AJA8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	69%
E9AKP0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9AT91	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9AVX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
E9AW05	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	79%
E9AXG9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
E9B0C7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	93%
E9B1F3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9B400	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	90%
F5H284	Homo sapiens	45%	100%
O00060	Uromyces fabae	43%	100%
O00845	Paramecium primaurelia	42%	100%
O02614	Leishmania major	52%	97%
O43447	Homo sapiens	41%	100%
O49605	Arabidopsis thaliana	45%	100%
O49886	Lupinus luteus	44%	100%
O74729	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	100%
O93826	Arthroderma benhamiae	38%	100%
O94273	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	100%
P0AFL3	Escherichia coli (strain K12)	26%	100%
P0AFL4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
P0AFL5	Escherichia coli O157:H7	26%	100%
P0C1H7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	47%	100%
P0C1H8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	46%	100%
P0C1H9	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	42%	100%
P0C1I0	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	41%	100%
P0C1I2	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	47%	73%
P0C1I3	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	41%	100%
P0C1I7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	44%	100%
P0C1I8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	46%	100%
P0C1I9	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	44%	68%
P0CP78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	43%	99%
P0CP79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	43%	99%
P0CP82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	41%	100%
P0CP83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	41%	100%
P0CP84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	37%	100%
P0CP85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	37%	100%
P0DN26	Homo sapiens	45%	100%
P0DN37	Homo sapiens	44%	100%
P10111	Rattus norvegicus	52%	100%
P10255	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	100%
P14088	Echinococcus granulosus	45%	100%
P14832	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	46%	100%
P14851	Cricetulus griseus	52%	100%
P15425	Drosophila melanogaster	34%	97%
P17742	Mus musculus	52%	100%
P18253	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	100%
P21568	Solanum lycopersicum	47%	100%
P21569	Zea mays	46%	100%
P22011	Candida albicans (strain SC5314 / ATCC MYA-2876)	44%	100%
P23284	Homo sapiens	42%	100%
P23285	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P24367	Gallus gallus	42%	100%
P24368	Rattus norvegicus	42%	100%
P24369	Mus musculus	41%	100%
P24525	Brassica napus	47%	100%
P25007	Drosophila melanogaster	43%	100%
P25334	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	72%
P25719	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	100%
P28517	Calliphora vicina	35%	98%
P29117	Rattus norvegicus	48%	100%
P30404	Bos taurus	47%	100%
P30405	Homo sapiens	48%	100%
P30412	Mus musculus	42%	100%
P34790	Arabidopsis thaliana	47%	100%
P35176	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P35627	Unspecified eudicot DB-1992	44%	100%
P45877	Homo sapiens	43%	100%
P52009	Caenorhabditis elegans	45%	100%
P52010	Caenorhabditis elegans	43%	100%
P52011	Caenorhabditis elegans	50%	100%
P52013	Caenorhabditis elegans	39%	100%
P52014	Caenorhabditis elegans	36%	100%
P52015	Caenorhabditis elegans	49%	100%
P52018	Caenorhabditis elegans	41%	100%
P54985	Blattella germanica	45%	100%
P62935	Bos taurus	51%	100%
P62936	Sus scrofa	51%	100%
P62937	Homo sapiens	51%	100%
P62938	Chlorocebus aethiops	51%	100%
P62940	Macaca mulatta	51%	100%
P62941	Papio anubis	51%	100%
P73789	Synechocystis sp. (strain PCC 6803 / Kazusa)	46%	100%
P77949	Streptomyces anulatus	33%	100%
P80311	Bos taurus	42%	100%
P84343	Neospora caninum	39%	100%
P91791	Hemicentrotus pulcherrimus	47%	100%
Q01490	Orpinomyces sp. (strain PC-2)	42%	100%
Q06118	Streptomyces anulatus	41%	100%
Q09637	Caenorhabditis elegans	38%	74%
Q0P5D0	Bos taurus	41%	100%
Q0ZQK3	Saguinus oedipus	51%	100%
Q0ZQK6	Symphalangus syndactylus	51%	100%
Q0ZQK7	Nomascus leucogenys	51%	100%
Q0ZQK8	Hylobates lar	51%	100%
Q0ZQL0	Gorilla gorilla gorilla	51%	100%
Q0ZQL1	Pan troglodytes	51%	100%
Q0ZQL2	Pan paniscus	51%	100%
Q1RMP7	Bos taurus	35%	75%
Q26516	Schistosoma japonicum	43%	100%
Q26548	Schistosoma mansoni	44%	84%
Q26551	Schistosoma mansoni	40%	100%
Q26565	Schistosoma mansoni	45%	100%
Q27774	Schistosoma japonicum	40%	100%
Q2TZ33	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	43%	100%
Q38867	Arabidopsis thaliana	49%	100%
Q38900	Arabidopsis thaliana	47%	100%
Q39613	Catharanthus roseus	47%	100%
Q42406	Arabidopsis thaliana	47%	100%
Q4G338	Haemonchus contortus	44%	71%
Q4I5R9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	42%	92%
Q4IPH4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	45%	100%
Q4P6X6	Ustilago maydis (strain 521 / FGSC 9021)	42%	100%
Q4Q1A6	Leishmania major	33%	100%
Q4Q424	Leishmania major	46%	100%
Q4Q6Q9	Leishmania major	45%	100%
Q4Q7V7	Leishmania major	33%	100%
Q4QBH1	Leishmania major	45%	100%
Q4QJ67	Leishmania major	42%	100%
Q4WCM6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	44%	100%
Q4WMB6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	30%	100%
Q4WP12	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	39%	100%
Q54SM3	Dictyostelium discoideum	44%	100%
Q5AQL0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	43%	100%
Q5B4R3	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	40%	100%
Q5BAH7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	100%
Q5E992	Bos taurus	36%	100%
Q5R723	Pongo abelii	45%	76%
Q5R8S7	Pongo pygmaeus	51%	100%
Q5UP71	Acanthamoeba polyphaga mimivirus	29%	98%
Q5ZLV2	Gallus gallus	38%	100%
Q6C4W6	Yarrowia lipolytica (strain CLIB 122 / E 150)	43%	100%
Q6DTV9	Aotus trivirgatus	51%	100%
Q7S7Z6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	80%
Q7SF72	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	36%	100%
Q7SG06	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	45%	100%
Q812D3	Rattus norvegicus	38%	100%
Q8HXS3	Felis catus	50%	100%
Q8IXY8	Homo sapiens	40%	74%
Q8L8W5	Arabidopsis thaliana	47%	100%
Q8LDP4	Arabidopsis thaliana	45%	100%
Q8SRE1	Encephalitozoon cuniculi (strain GB-M1)	45%	100%
Q8W171	Glycine max	47%	100%
Q8X166	Aspergillus niger	39%	100%
Q99KR7	Mus musculus	48%	100%
Q9ASS6	Arabidopsis thaliana	42%	88%
Q9D0W5	Mus musculus	36%	100%
Q9D6D8	Mus musculus	37%	73%
Q9D6L8	Mus musculus	37%	100%
Q9H2H8	Homo sapiens	38%	100%
Q9LIK6	Arabidopsis thaliana	38%	99%
Q9QZH3	Mus musculus	45%	76%
Q9SKQ0	Arabidopsis thaliana	45%	100%
Q9SP02	Arabidopsis thaliana	45%	100%
Q9TTC6	Oryctolagus cuniculus	49%	100%
Q9TW32	Dictyostelium discoideum	45%	100%
Q9UA41	Dictyostelium discoideum	43%	100%
Q9UNP9	Homo sapiens	45%	76%
Q9V3G3	Drosophila melanogaster	47%	76%
Q9Y3C6	Homo sapiens	36%	100%
Q9Y536	Homo sapiens	45%	100%
Q9ZVJ4	Arabidopsis thaliana	42%	100%
V5B2A0	Trypanosoma cruzi	49%	89%
V5B9Y6	Trypanosoma cruzi	28%	74%
V5BGX2	Trypanosoma cruzi	36%	86%
V5BHF5	Trypanosoma cruzi	48%	100%
V5D532	Trypanosoma cruzi	41%	100%
V5DJ29	Trypanosoma cruzi	32%	71%