Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBI1_LEIMA

TriTrypDb:

LmjF.22.1660 , LMJLV39_220022600 , LMJSD75_220023200

Length:

616

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBI1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBI1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	11	15	PF00656	0.620
CLV_C14_Caspase3-7	513	517	PF00656	0.540
CLV_C14_Caspase3-7	567	571	PF00656	0.679
CLV_NRD_NRD_1	385	387	PF00675	0.575
CLV_NRD_NRD_1	416	418	PF00675	0.441
CLV_NRD_NRD_1	435	437	PF00675	0.428
CLV_NRD_NRD_1	527	529	PF00675	0.472
CLV_PCSK_KEX2_1	385	387	PF00082	0.575
CLV_PCSK_KEX2_1	416	418	PF00082	0.441
CLV_PCSK_KEX2_1	435	437	PF00082	0.428
CLV_PCSK_KEX2_1	527	529	PF00082	0.472
CLV_PCSK_KEX2_1	603	605	PF00082	0.500
CLV_PCSK_PC1ET2_1	603	605	PF00082	0.500
CLV_PCSK_SKI1_1	217	221	PF00082	0.490
CLV_PCSK_SKI1_1	386	390	PF00082	0.644
CLV_PCSK_SKI1_1	416	420	PF00082	0.534
CLV_PCSK_SKI1_1	451	455	PF00082	0.490
CLV_Separin_Metazoa	560	564	PF03568	0.368
DEG_APCC_DBOX_1	415	423	PF00400	0.532
DEG_Nend_Nbox_1	1	3	PF02207	0.707
DEG_SPOP_SBC_1	186	190	PF00917	0.675
DEG_SPOP_SBC_1	569	573	PF00917	0.569
DOC_CKS1_1	540	545	PF01111	0.607
DOC_CYCLIN_RxL_1	214	221	PF00134	0.514
DOC_CYCLIN_RxL_1	413	421	PF00134	0.520
DOC_CYCLIN_yCln2_LP_2	126	132	PF00134	0.581
DOC_MAPK_gen_1	320	329	PF00069	0.511
DOC_MAPK_gen_1	342	352	PF00069	0.445
DOC_MAPK_gen_1	416	424	PF00069	0.463
DOC_MAPK_MEF2A_6	320	329	PF00069	0.511
DOC_MAPK_MEF2A_6	345	352	PF00069	0.487
DOC_PP1_RVXF_1	231	238	PF00149	0.465
DOC_PP2B_LxvP_1	121	124	PF13499	0.701
DOC_PP2B_LxvP_1	126	129	PF13499	0.684
DOC_USP7_MATH_1	110	114	PF00917	0.541
DOC_USP7_MATH_1	139	143	PF00917	0.613
DOC_USP7_MATH_1	177	181	PF00917	0.698
DOC_USP7_MATH_1	186	190	PF00917	0.688
DOC_USP7_MATH_1	222	226	PF00917	0.562
DOC_USP7_MATH_1	278	282	PF00917	0.528
DOC_USP7_MATH_1	461	465	PF00917	0.648
DOC_USP7_MATH_1	498	502	PF00917	0.662
DOC_USP7_MATH_1	526	530	PF00917	0.527
DOC_USP7_MATH_1	93	97	PF00917	0.556
DOC_WW_Pin1_4	135	140	PF00397	0.571
DOC_WW_Pin1_4	218	223	PF00397	0.563
DOC_WW_Pin1_4	502	507	PF00397	0.672
DOC_WW_Pin1_4	539	544	PF00397	0.587
DOC_WW_Pin1_4	588	593	PF00397	0.657
DOC_WW_Pin1_4	72	77	PF00397	0.693
LIG_14-3-3_CanoR_1	179	184	PF00244	0.720
LIG_14-3-3_CanoR_1	37	45	PF00244	0.693
LIG_14-3-3_CanoR_1	385	389	PF00244	0.611
LIG_14-3-3_CanoR_1	417	423	PF00244	0.493
LIG_14-3-3_CanoR_1	527	535	PF00244	0.498
LIG_14-3-3_CanoR_1	609	615	PF00244	0.451
LIG_Actin_WH2_2	411	428	PF00022	0.512
LIG_APCC_ABBA_1	22	27	PF00400	0.644
LIG_APCC_ABBA_1	303	308	PF00400	0.541
LIG_APCC_ABBA_1	518	523	PF00400	0.528
LIG_CaM_IQ_9	259	274	PF13499	0.565
LIG_DLG_GKlike_1	179	187	PF00625	0.679
LIG_EH1_1	575	583	PF00400	0.549
LIG_eIF4E_1	576	582	PF01652	0.554
LIG_FHA_1	139	145	PF00498	0.516
LIG_FHA_1	189	195	PF00498	0.581
LIG_FHA_1	243	249	PF00498	0.550
LIG_FHA_1	299	305	PF00498	0.521
LIG_FHA_1	400	406	PF00498	0.518
LIG_FHA_1	535	541	PF00498	0.512
LIG_FHA_1	609	615	PF00498	0.339
LIG_FHA_1	69	75	PF00498	0.666
LIG_IBAR_NPY_1	23	25	PF08397	0.652
LIG_LIR_Gen_1	160	170	PF02991	0.567
LIG_LIR_Gen_1	323	332	PF02991	0.421
LIG_LIR_Gen_1	428	433	PF02991	0.456
LIG_LIR_Gen_1	464	471	PF02991	0.550
LIG_LIR_Nem_3	160	165	PF02991	0.521
LIG_LIR_Nem_3	323	327	PF02991	0.442
LIG_LIR_Nem_3	397	401	PF02991	0.528
LIG_LIR_Nem_3	428	432	PF02991	0.462
LIG_LIR_Nem_3	464	468	PF02991	0.556
LIG_NRBOX	418	424	PF00104	0.559
LIG_PCNA_yPIPBox_3	342	356	PF02747	0.470
LIG_PCNA_yPIPBox_3	579	588	PF02747	0.566
LIG_PDZ_Class_2	611	616	PF00595	0.543
LIG_Pex14_1	384	388	PF04695	0.528
LIG_SH2_PTP2	162	165	PF00017	0.564
LIG_SH2_PTP2	324	327	PF00017	0.493
LIG_SH2_SRC	98	101	PF00017	0.617
LIG_SH2_STAP1	401	405	PF00017	0.419
LIG_SH2_STAT3	576	579	PF00017	0.549
LIG_SH2_STAT5	162	165	PF00017	0.462
LIG_SH2_STAT5	168	171	PF00017	0.481
LIG_SH2_STAT5	324	327	PF00017	0.493
LIG_SH2_STAT5	401	404	PF00017	0.436
LIG_SH2_STAT5	576	579	PF00017	0.534
LIG_SH2_STAT5	601	604	PF00017	0.444
LIG_SH2_STAT5	98	101	PF00017	0.641
LIG_SH3_3	169	175	PF00018	0.589
LIG_SH3_3	224	230	PF00018	0.477
LIG_SH3_3	245	251	PF00018	0.525
LIG_SUMO_SIM_anti_2	421	426	PF11976	0.605
LIG_WRC_WIRS_1	254	259	PF05994	0.393
MOD_CDK_SPxxK_3	588	595	PF00069	0.651
MOD_CDK_SPxxK_3	72	79	PF00069	0.696
MOD_CK1_1	138	144	PF00069	0.544
MOD_CK1_1	188	194	PF00069	0.625
MOD_CK1_1	316	322	PF00069	0.517
MOD_CK1_1	464	470	PF00069	0.541
MOD_CK1_1	501	507	PF00069	0.679
MOD_CK1_1	75	81	PF00069	0.737
MOD_CK1_1	82	88	PF00069	0.635
MOD_CK2_1	278	284	PF00069	0.418
MOD_CK2_1	3	9	PF00069	0.627
MOD_CK2_1	40	46	PF00069	0.646
MOD_CK2_1	425	431	PF00069	0.498
MOD_CK2_1	507	513	PF00069	0.667
MOD_CK2_1	75	81	PF00069	0.773
MOD_GlcNHglycan	141	144	PF01048	0.629
MOD_GlcNHglycan	159	162	PF01048	0.487
MOD_GlcNHglycan	199	202	PF01048	0.647
MOD_GlcNHglycan	212	216	PF01048	0.543
MOD_GlcNHglycan	269	272	PF01048	0.422
MOD_GlcNHglycan	298	301	PF01048	0.443
MOD_GlcNHglycan	315	318	PF01048	0.332
MOD_GlcNHglycan	337	340	PF01048	0.528
MOD_GlcNHglycan	476	479	PF01048	0.369
MOD_GlcNHglycan	528	531	PF01048	0.600
MOD_GlcNHglycan	572	575	PF01048	0.518
MOD_GlcNHglycan	68	71	PF01048	0.646
MOD_GlcNHglycan	95	98	PF01048	0.634
MOD_GSK3_1	135	142	PF00069	0.514
MOD_GSK3_1	153	160	PF00069	0.605
MOD_GSK3_1	175	182	PF00069	0.622
MOD_GSK3_1	184	191	PF00069	0.612
MOD_GSK3_1	218	225	PF00069	0.519
MOD_GSK3_1	23	30	PF00069	0.606
MOD_GSK3_1	492	499	PF00069	0.576
MOD_GSK3_1	501	508	PF00069	0.676
MOD_GSK3_1	68	75	PF00069	0.686
MOD_GSK3_1	89	96	PF00069	0.603
MOD_N-GLC_1	588	593	PF02516	0.579
MOD_NEK2_1	185	190	PF00069	0.686
MOD_NEK2_1	2	7	PF00069	0.732
MOD_NEK2_1	289	294	PF00069	0.422
MOD_NEK2_1	298	303	PF00069	0.348
MOD_NEK2_1	418	423	PF00069	0.535
MOD_NEK2_1	425	430	PF00069	0.553
MOD_NEK2_1	492	497	PF00069	0.566
MOD_NEK2_1	599	604	PF00069	0.529
MOD_NEK2_1	91	96	PF00069	0.668
MOD_NEK2_2	110	115	PF00069	0.665
MOD_NEK2_2	3	8	PF00069	0.654
MOD_NEK2_2	401	406	PF00069	0.423
MOD_PIKK_1	608	614	PF00454	0.339
MOD_PIKK_1	68	74	PF00454	0.571
MOD_PIKK_1	79	85	PF00454	0.750
MOD_PKA_2	178	184	PF00069	0.723
MOD_PKA_2	344	350	PF00069	0.469
MOD_PKA_2	384	390	PF00069	0.612
MOD_PKA_2	425	431	PF00069	0.573
MOD_PKA_2	492	498	PF00069	0.573
MOD_PKA_2	526	532	PF00069	0.505
MOD_PKA_2	608	614	PF00069	0.339
MOD_PKB_1	47	55	PF00069	0.489
MOD_Plk_1	18	24	PF00069	0.605
MOD_Plk_1	211	217	PF00069	0.510
MOD_Plk_1	8	14	PF00069	0.677
MOD_Plk_4	153	159	PF00069	0.504
MOD_Plk_4	199	205	PF00069	0.520
MOD_Plk_4	223	229	PF00069	0.500
MOD_Plk_4	27	33	PF00069	0.373
MOD_Plk_4	418	424	PF00069	0.469
MOD_Plk_4	464	470	PF00069	0.595
MOD_Plk_4	8	14	PF00069	0.683
MOD_ProDKin_1	135	141	PF00069	0.565
MOD_ProDKin_1	218	224	PF00069	0.561
MOD_ProDKin_1	502	508	PF00069	0.672
MOD_ProDKin_1	539	545	PF00069	0.598
MOD_ProDKin_1	588	594	PF00069	0.656
MOD_ProDKin_1	72	78	PF00069	0.695
MOD_SUMO_rev_2	591	596	PF00179	0.619
TRG_DiLeu_BaEn_1	531	536	PF01217	0.572
TRG_DiLeu_BaEn_1	560	565	PF01217	0.484
TRG_DiLeu_BaEn_4	358	364	PF01217	0.550
TRG_DiLeu_BaLyEn_6	161	166	PF01217	0.328
TRG_DiLeu_BaLyEn_6	285	290	PF01217	0.578
TRG_DiLeu_BaLyEn_6	414	419	PF01217	0.508
TRG_DiLeu_BaLyEn_6	550	555	PF01217	0.533
TRG_ENDOCYTIC_2	162	165	PF00928	0.464
TRG_ENDOCYTIC_2	25	28	PF00928	0.641
TRG_ENDOCYTIC_2	324	327	PF00928	0.436
TRG_ER_diArg_1	384	386	PF00400	0.585
TRG_ER_diArg_1	416	418	PF00400	0.445
TRG_ER_diArg_1	434	436	PF00400	0.490
TRG_ER_diArg_1	48	51	PF00400	0.686
TRG_NES_CRM1_1	135	148	PF08389	0.497

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDK4	Leptomonas seymouri	48%	99%
A0A1X0NU19	Trypanosomatidae	28%	100%
A0A3R7K6E0	Trypanosoma rangeli	29%	100%
A0A3S5H7B4	Leishmania donovani	92%	100%
A4HCK7	Leishmania braziliensis	76%	100%
A4I025	Leishmania infantum	92%	100%
E9AVZ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%