V-type proton ATPase proteolipid subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

vacuolar type h+ ATPase subunit, putative

Species:

Leishmania major

UniProt:

Q4QBG2_LEIMA

TriTrypDb:

LmjF.23.0130 , LMJLV39_230006300 , LMJSD75_230006300

Length:

167

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 9, no: 20
NetGPI	no	yes: 0, no: 29

Show entries

Cellular components
Term	Name	Level	Count
GO:0005774	vacuolar membrane	5	30
GO:0016020	membrane	2	30
GO:0031090	organelle membrane	3	30
GO:0032991	protein-containing complex	1	30
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	3	30
GO:0033179	proton-transporting V-type ATPase, V0 domain	4	30
GO:0098588	bounding membrane of organelle	4	30
GO:0098796	membrane protein complex	2	30
GO:0110165	cellular anatomical entity	1	30

Previous1Next

Expansion

Sequence features

Q4QBG2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBG2

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	19
GO:0005215	transporter activity	1	30
GO:0008324	monoatomic cation transmembrane transporter activity	4	30
GO:0009678	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	5	30
GO:0015075	monoatomic ion transmembrane transporter activity	3	30
GO:0015078	proton transmembrane transporter activity	5	30
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	30
GO:0015399	primary active transmembrane transporter activity	4	30
GO:0016787	hydrolase activity	2	19
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3	30

Previous1 2Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
DOC_MAPK_DCC_7	127	135	PF00069	0.437
DOC_MAPK_DCC_7	51	61	PF00069	0.440
DOC_MAPK_gen_1	124	134	PF00069	0.442
DOC_MAPK_gen_1	51	59	PF00069	0.440
DOC_MAPK_MEF2A_6	124	132	PF00069	0.440
DOC_MAPK_MEF2A_6	54	61	PF00069	0.440
DOC_USP7_MATH_1	160	164	PF00917	0.276
LIG_APCC_ABBA_1	135	140	PF00400	0.285
LIG_BIR_II_1	1	5	PF00653	0.435
LIG_FHA_1	123	129	PF00498	0.437

Previous1 2 3 4Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3G9	Leptomonas seymouri	30%	75%
A0A0N0P7K0	Leptomonas seymouri	60%	85%
A0A0N1HSG6	Leptomonas seymouri	66%	88%
A0A0N1I3H6	Leptomonas seymouri	90%	100%
A0A0S4IU71	Bodo saltans	63%	97%
A0A0S4JFM4	Bodo saltans	78%	94%
A0A0S4KKA5	Bodo saltans	62%	86%
A0A1X0NGC8	Trypanosomatidae	85%	100%
A0A1X0NHL5	Trypanosomatidae	64%	87%
A0A1X0NZ73	Trypanosomatidae	61%	92%

Previous1 2 3 4 5…10Next