Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QBF1_LEIMA

TriTrypDb:

LmjF.23.0230 , LMJLV39_230007500 , LMJSD75_230007800

Length:

185

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

Q4QBF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBF1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.362
CLV_NRD_NRD_1	11	13	PF00675	0.618
CLV_NRD_NRD_1	181	183	PF00675	0.451
CLV_NRD_NRD_1	24	26	PF00675	0.651
CLV_NRD_NRD_1	39	41	PF00675	0.575
CLV_PCSK_FUR_1	22	26	PF00082	0.655
CLV_PCSK_KEX2_1	10	12	PF00082	0.625
CLV_PCSK_KEX2_1	104	106	PF00082	0.362
CLV_PCSK_KEX2_1	125	127	PF00082	0.466
CLV_PCSK_KEX2_1	181	183	PF00082	0.439
CLV_PCSK_KEX2_1	24	26	PF00082	0.645
CLV_PCSK_KEX2_1	39	41	PF00082	0.566
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.385
CLV_PCSK_PC7_1	100	106	PF00082	0.361
CLV_PCSK_PC7_1	6	12	PF00082	0.636
CLV_PCSK_SKI1_1	144	148	PF00082	0.452
DEG_APCC_DBOX_1	61	69	PF00400	0.389
DEG_Nend_UBRbox_1	1	4	PF02207	0.424
DOC_MAPK_gen_1	10	17	PF00069	0.426
DOC_MAPK_MEF2A_6	10	17	PF00069	0.476
DOC_MAPK_NFAT4_5	10	18	PF00069	0.477
DOC_PP1_RVXF_1	73	80	PF00149	0.296
LIG_FHA_1	26	32	PF00498	0.590
LIG_FHA_1	89	95	PF00498	0.369
LIG_LIR_Apic_2	55	61	PF02991	0.434
LIG_LIR_Gen_1	80	89	PF02991	0.333
LIG_LIR_Nem_3	80	84	PF02991	0.362
LIG_Pex14_2	88	92	PF04695	0.386
LIG_SH2_STAT5	14	17	PF00017	0.479
LIG_SH3_3	143	149	PF00018	0.553
LIG_SH3_3	79	85	PF00018	0.318
LIG_TRAF2_1	111	114	PF00917	0.621
LIG_WRC_WIRS_1	89	94	PF05994	0.369
MOD_CK2_1	177	183	PF00069	0.664
MOD_Cter_Amidation	8	11	PF01082	0.559
MOD_GlcNHglycan	54	57	PF01048	0.603
MOD_GlcNHglycan	7	10	PF01048	0.563
MOD_N-GLC_1	25	30	PF02516	0.712
MOD_NEK2_1	15	20	PF00069	0.428
MOD_NEK2_1	52	57	PF00069	0.416
MOD_NEK2_1	77	82	PF00069	0.440
MOD_NEK2_1	88	93	PF00069	0.384
MOD_PKA_2	5	11	PF00069	0.436
MOD_PKA_2	61	67	PF00069	0.392
MOD_Plk_4	142	148	PF00069	0.621
MOD_Plk_4	88	94	PF00069	0.335
TRG_ENDOCYTIC_2	14	17	PF00928	0.560
TRG_ER_diArg_1	10	12	PF00400	0.423
TRG_ER_diArg_1	104	107	PF00400	0.571
TRG_ER_diArg_1	24	27	PF00400	0.440
TRG_Pf-PMV_PEXEL_1	148	152	PF00026	0.464
TRG_PTS2	1	35	PF00400	0.457

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Y2	Leptomonas seymouri	45%	100%
A0A3S7WXI2	Leishmania donovani	89%	100%
A4HCN8	Leishmania braziliensis	66%	100%
A4I063	Leishmania infantum	90%	100%
E9AW26	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	97%