Putative cytochrome c oxidase subunit 10

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome c oxidase subunit 10, putative

Species:

Leishmania major

UniProt:

Q4QBD7_LEIMA

TriTrypDb:

LmjF.23.0370 , LMJLV39_230009200 , LMJSD75_230009400

Length:

118

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBD7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBD7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	5
GO:0016491	oxidoreductase activity	2	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	35	39	PF00656	0.434
CLV_NRD_NRD_1	2	4	PF00675	0.534
CLV_NRD_NRD_1	51	53	PF00675	0.440
CLV_NRD_NRD_1	86	88	PF00675	0.423
CLV_PCSK_KEX2_1	2	4	PF00082	0.534
CLV_PCSK_KEX2_1	51	53	PF00082	0.488
CLV_PCSK_KEX2_1	86	88	PF00082	0.419
CLV_PCSK_PC7_1	47	53	PF00082	0.376
CLV_PCSK_SKI1_1	100	104	PF00082	0.355
CLV_PCSK_SKI1_1	2	6	PF00082	0.642
CLV_PCSK_SKI1_1	79	83	PF00082	0.414
CLV_PCSK_SKI1_1	87	91	PF00082	0.372
DEG_Nend_UBRbox_1	1	4	PF02207	0.611
DOC_CKS1_1	80	85	PF01111	0.337
DOC_CYCLIN_RxL_1	18	28	PF00134	0.490
DOC_CYCLIN_yCln2_LP_2	23	29	PF00134	0.493
DOC_PP1_RVXF_1	19	26	PF00149	0.516
DOC_PP1_RVXF_1	60	67	PF00149	0.419
DOC_PP1_RVXF_1	85	92	PF00149	0.405
DOC_WW_Pin1_4	25	30	PF00397	0.555
DOC_WW_Pin1_4	79	84	PF00397	0.413
LIG_14-3-3_CanoR_1	100	105	PF00244	0.400
LIG_14-3-3_CanoR_1	2	11	PF00244	0.635
LIG_deltaCOP1_diTrp_1	88	98	PF00928	0.508
LIG_FHA_1	101	107	PF00498	0.371
LIG_FHA_1	18	24	PF00498	0.622
LIG_FHA_1	3	9	PF00498	0.617
LIG_FHA_2	80	86	PF00498	0.403
LIG_HCF-1_HBM_1	111	114	PF13415	0.400
LIG_LIR_Gen_1	63	73	PF02991	0.402
LIG_LIR_Nem_3	63	69	PF02991	0.390
LIG_LIR_Nem_3	97	102	PF02991	0.348
LIG_REV1ctd_RIR_1	96	104	PF16727	0.371
LIG_SH2_PTP2	101	104	PF00017	0.351
LIG_SH2_SRC	36	39	PF00017	0.457
LIG_SH2_STAT5	101	104	PF00017	0.460
LIG_SH2_STAT5	36	39	PF00017	0.421
LIG_SH3_3	23	29	PF00018	0.538
LIG_SUMO_SIM_par_1	30	35	PF11976	0.452
LIG_TRAF2_1	82	85	PF00917	0.486
MOD_CDK_SPxxK_3	79	86	PF00069	0.407
MOD_CK2_1	79	85	PF00069	0.396
MOD_GSK3_1	100	107	PF00069	0.382
MOD_NEK2_1	104	109	PF00069	0.369
MOD_PKA_1	2	8	PF00069	0.620
MOD_PKA_2	2	8	PF00069	0.633
MOD_ProDKin_1	25	31	PF00069	0.553
MOD_ProDKin_1	79	85	PF00069	0.414
TRG_ENDOCYTIC_2	101	104	PF00928	0.411
TRG_ER_diArg_1	1	3	PF00400	0.542
TRG_ER_diArg_1	51	53	PF00400	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKB5	Leptomonas seymouri	86%	99%
A0A0S4JCT0	Bodo saltans	71%	100%
A0A1X0NX91	Trypanosomatidae	74%	100%
A0A3S7WXI5	Leishmania donovani	98%	100%
A4HCQ2	Leishmania braziliensis	86%	99%
A4I077	Leishmania infantum	98%	100%
D0A9J4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
D0A9J6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
E9AW41	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%