LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4QBD2_LEIMA
TriTrypDb:
LmjF.23.0420 * , LMJLV39_230009800 * , LMJSD75_230010000 *
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBD2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBD2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 46 48 PF00675 0.645
CLV_PCSK_KEX2_1 12 14 PF00082 0.491
CLV_PCSK_KEX2_1 46 48 PF00082 0.645
CLV_PCSK_PC1ET2_1 12 14 PF00082 0.491
DOC_PP4_FxxP_1 59 62 PF00568 0.626
DOC_USP7_MATH_1 133 137 PF00917 0.704
DOC_USP7_MATH_1 36 40 PF00917 0.584
DOC_WW_Pin1_4 32 37 PF00397 0.664
LIG_14-3-3_CanoR_1 92 99 PF00244 0.487
LIG_Actin_WH2_2 76 94 PF00022 0.514
LIG_FHA_2 9 15 PF00498 0.574
LIG_FHA_2 92 98 PF00498 0.629
LIG_GBD_Chelix_1 83 91 PF00786 0.483
LIG_LIR_Nem_3 76 80 PF02991 0.567
LIG_LIR_Nem_3 93 99 PF02991 0.495
LIG_NRBOX 86 92 PF00104 0.487
LIG_SH2_STAT3 99 102 PF00017 0.490
LIG_SH2_STAT5 10 13 PF00017 0.586
LIG_SH3_3 49 55 PF00018 0.723
LIG_SH3_3 58 64 PF00018 0.583
LIG_TRAF2_1 135 138 PF00917 0.569
LIG_UBA3_1 5 12 PF00899 0.481
MOD_CK1_1 16 22 PF00069 0.562
MOD_CK1_1 24 30 PF00069 0.544
MOD_CK1_1 32 38 PF00069 0.593
MOD_CK1_1 8 14 PF00069 0.596
MOD_GlcNHglycan 20 23 PF01048 0.750
MOD_GlcNHglycan 40 43 PF01048 0.641
MOD_GSK3_1 1 8 PF00069 0.637
MOD_GSK3_1 120 127 PF00069 0.591
MOD_GSK3_1 133 140 PF00069 0.510
MOD_GSK3_1 21 28 PF00069 0.480
MOD_GSK3_1 30 37 PF00069 0.559
MOD_GSK3_1 69 76 PF00069 0.635
MOD_N-GLC_1 124 129 PF02516 0.455
MOD_NEK2_1 1 6 PF00069 0.630
MOD_NEK2_1 124 129 PF00069 0.499
MOD_NEK2_1 40 45 PF00069 0.644
MOD_PIKK_1 133 139 PF00454 0.566
MOD_PK_1 13 19 PF00069 0.574
MOD_PKA_2 91 97 PF00069 0.487
MOD_Plk_1 120 126 PF00069 0.639
MOD_Plk_1 13 19 PF00069 0.574
MOD_Plk_4 1 7 PF00069 0.667
MOD_ProDKin_1 32 38 PF00069 0.665
TRG_NES_CRM1_1 107 121 PF08389 0.479
TRG_Pf-PMV_PEXEL_1 65 69 PF00026 0.528

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ILZ4 Leishmania donovani 93% 91%
A4HCQ6 Leishmania braziliensis 63% 100%
A4I081 Leishmania infantum 92% 91%
E9AW45 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS