LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QBC7_LEIMA
TriTrypDb:
LmjF.23.0470 , LMJLV39_230010300 , LMJSD75_230010500
Length:
349

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QBC7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QBC7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 335 339 PF00656 0.636
CLV_MEL_PAP_1 308 314 PF00089 0.556
CLV_NRD_NRD_1 115 117 PF00675 0.597
CLV_NRD_NRD_1 135 137 PF00675 0.567
CLV_NRD_NRD_1 238 240 PF00675 0.675
CLV_NRD_NRD_1 319 321 PF00675 0.575
CLV_NRD_NRD_1 89 91 PF00675 0.609
CLV_PCSK_KEX2_1 115 117 PF00082 0.597
CLV_PCSK_KEX2_1 135 137 PF00082 0.567
CLV_PCSK_KEX2_1 240 242 PF00082 0.622
CLV_PCSK_KEX2_1 89 91 PF00082 0.609
CLV_PCSK_PC1ET2_1 240 242 PF00082 0.622
CLV_PCSK_SKI1_1 115 119 PF00082 0.657
CLV_PCSK_SKI1_1 185 189 PF00082 0.490
CLV_PCSK_SKI1_1 215 219 PF00082 0.447
CLV_PCSK_SKI1_1 272 276 PF00082 0.504
DEG_COP1_1 256 265 PF00400 0.592
DOC_MAPK_gen_1 89 95 PF00069 0.623
DOC_PP2B_LxvP_1 158 161 PF13499 0.584
DOC_USP7_MATH_1 127 131 PF00917 0.664
DOC_USP7_MATH_1 263 267 PF00917 0.665
DOC_USP7_MATH_1 330 334 PF00917 0.677
DOC_USP7_MATH_1 339 343 PF00917 0.532
DOC_USP7_MATH_1 99 103 PF00917 0.634
DOC_WW_Pin1_4 134 139 PF00397 0.648
DOC_WW_Pin1_4 167 172 PF00397 0.467
DOC_WW_Pin1_4 286 291 PF00397 0.641
LIG_14-3-3_CanoR_1 115 121 PF00244 0.664
LIG_14-3-3_CanoR_1 20 28 PF00244 0.567
LIG_14-3-3_CanoR_1 241 250 PF00244 0.623
LIG_14-3-3_CanoR_1 272 277 PF00244 0.585
LIG_14-3-3_CanoR_1 54 58 PF00244 0.815
LIG_14-3-3_CanoR_1 8 15 PF00244 0.696
LIG_Actin_WH2_2 204 221 PF00022 0.458
LIG_BIR_II_1 1 5 PF00653 0.702
LIG_EVH1_1 158 162 PF00568 0.581
LIG_FHA_1 106 112 PF00498 0.648
LIG_FHA_1 121 127 PF00498 0.500
LIG_FHA_1 194 200 PF00498 0.441
LIG_FHA_1 226 232 PF00498 0.660
LIG_FHA_1 287 293 PF00498 0.669
LIG_FHA_1 38 44 PF00498 0.636
LIG_FHA_1 99 105 PF00498 0.642
LIG_LIR_Apic_2 123 127 PF02991 0.671
LIG_MYND_1 163 167 PF01753 0.634
LIG_PDZ_Class_2 344 349 PF00595 0.563
LIG_SH2_PTP2 82 85 PF00017 0.533
LIG_SH2_SRC 33 36 PF00017 0.591
LIG_SH2_SRC 82 85 PF00017 0.554
LIG_SH2_STAT5 213 216 PF00017 0.470
LIG_SH2_STAT5 33 36 PF00017 0.575
LIG_SH2_STAT5 82 85 PF00017 0.533
LIG_SH3_3 154 160 PF00018 0.672
LIG_SH3_3 16 22 PF00018 0.599
LIG_SH3_3 165 171 PF00018 0.522
LIG_SH3_3 299 305 PF00018 0.646
LIG_SH3_3 78 84 PF00018 0.598
LIG_SUMO_SIM_par_1 178 184 PF11976 0.509
LIG_TRAF2_1 181 184 PF00917 0.388
MOD_CK1_1 11 17 PF00069 0.682
MOD_CK1_1 170 176 PF00069 0.420
MOD_CK1_1 266 272 PF00069 0.647
MOD_CK1_1 285 291 PF00069 0.599
MOD_CK1_1 314 320 PF00069 0.637
MOD_CK1_1 333 339 PF00069 0.547
MOD_CK1_1 59 65 PF00069 0.702
MOD_CK2_1 223 229 PF00069 0.591
MOD_CK2_1 239 245 PF00069 0.625
MOD_Cter_Amidation 113 116 PF01082 0.594
MOD_GlcNHglycan 100 104 PF01048 0.632
MOD_GlcNHglycan 129 132 PF01048 0.649
MOD_GlcNHglycan 23 26 PF01048 0.709
MOD_GlcNHglycan 233 236 PF01048 0.723
MOD_GlcNHglycan 257 260 PF01048 0.722
MOD_GlcNHglycan 265 268 PF01048 0.634
MOD_GlcNHglycan 316 319 PF01048 0.618
MOD_GlcNHglycan 322 326 PF01048 0.658
MOD_GlcNHglycan 327 330 PF01048 0.681
MOD_GlcNHglycan 58 61 PF01048 0.630
MOD_GSK3_1 116 123 PF00069 0.612
MOD_GSK3_1 263 270 PF00069 0.746
MOD_GSK3_1 282 289 PF00069 0.606
MOD_GSK3_1 310 317 PF00069 0.609
MOD_GSK3_1 321 328 PF00069 0.549
MOD_GSK3_1 95 102 PF00069 0.588
MOD_N-GLC_1 272 277 PF02516 0.642
MOD_NEK2_1 105 110 PF00069 0.728
MOD_NEK2_1 193 198 PF00069 0.505
MOD_NEK2_1 28 33 PF00069 0.576
MOD_NEK2_1 282 287 PF00069 0.659
MOD_NEK2_1 37 42 PF00069 0.557
MOD_NEK2_1 88 93 PF00069 0.585
MOD_NEK2_2 151 156 PF00069 0.644
MOD_PIKK_1 105 111 PF00454 0.743
MOD_PIKK_1 116 122 PF00454 0.681
MOD_PIKK_1 193 199 PF00454 0.391
MOD_PIKK_1 26 32 PF00454 0.550
MOD_PIKK_1 267 273 PF00454 0.667
MOD_PIKK_1 37 43 PF00454 0.590
MOD_PIKK_1 44 50 PF00454 0.593
MOD_PIKK_1 8 14 PF00454 0.636
MOD_PKA_1 239 245 PF00069 0.625
MOD_PKA_2 310 316 PF00069 0.588
MOD_PKA_2 53 59 PF00069 0.694
MOD_PKA_2 88 94 PF00069 0.577
MOD_PKB_1 239 247 PF00069 0.625
MOD_Plk_1 151 157 PF00069 0.701
MOD_Plk_1 272 278 PF00069 0.589
MOD_Plk_4 29 35 PF00069 0.590
MOD_ProDKin_1 134 140 PF00069 0.649
MOD_ProDKin_1 167 173 PF00069 0.459
MOD_ProDKin_1 286 292 PF00069 0.643
TRG_DiLeu_BaEn_1 195 200 PF01217 0.480
TRG_DiLeu_BaEn_2 342 348 PF01217 0.565
TRG_DiLeu_BaLyEn_6 277 282 PF01217 0.664
TRG_ER_diArg_1 238 241 PF00400 0.683
TRG_ER_diArg_1 88 90 PF00400 0.600
TRG_NLS_MonoExtC_3 238 243 PF00514 0.646
TRG_NLS_MonoExtN_4 238 244 PF00514 0.598
TRG_Pf-PMV_PEXEL_1 116 120 PF00026 0.667
TRG_Pf-PMV_PEXEL_1 280 284 PF00026 0.661

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1P9J6 Leptomonas seymouri 34% 100%
A0A3S7WXL1 Leishmania donovani 88% 100%
A4HCR1 Leishmania braziliensis 62% 100%
A4I086 Leishmania infantum 88% 100%
E9AW50 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS