LeishMANIAdb
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Hydrophilic acylated surface protein b

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hydrophilic acylated surface protein b
Gene product:
hydrophilic acylated surface protein b
Species:
Leishmania major
UniProt:
Q4QB56_LEIMA
TriTrypDb:
LmjF.23.1070
Length:
177

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QB56
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QB56

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 150 154 PF00656 0.610
CLV_NRD_NRD_1 35 37 PF00675 0.687
DOC_USP7_MATH_1 13 17 PF00917 0.605
DOC_USP7_MATH_1 32 36 PF00917 0.694
DOC_USP7_UBL2_3 15 19 PF12436 0.585
DOC_USP7_UBL2_3 7 11 PF12436 0.650
DOC_WW_Pin1_4 51 56 PF00397 0.572
MOD_CK1_1 3 9 PF00069 0.594
MOD_CK1_1 35 41 PF00069 0.617
MOD_CK2_1 19 25 PF00069 0.575
MOD_CK2_1 6 12 PF00069 0.629
MOD_GlcNHglycan 15 18 PF01048 0.587
MOD_GlcNHglycan 32 35 PF01048 0.691
MOD_GlcNHglycan 37 40 PF01048 0.746
MOD_GlcNHglycan 8 11 PF01048 0.649
MOD_GSK3_1 19 26 PF00069 0.700
MOD_N-GLC_1 23 28 PF02516 0.585
MOD_N-GLC_1 30 35 PF02516 0.603
MOD_NEK2_1 1 6 PF00069 0.596
MOD_NMyristoyl 1 7 PF02799 0.647
MOD_PKA_2 35 41 PF00069 0.721
MOD_ProDKin_1 51 57 PF00069 0.576

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IFV6 Leishmania donovani 57% 95%
A4I0F4 Leishmania infantum 61% 72%
E9AWB7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 45% 86%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS