Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QB27_LEIMA

TriTrypDb:

LmjF.23.1263 , LMJLV39_230022500 , LMJSD75_230022900

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QB27

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QB27

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	197	201	PF00656	0.590
CLV_NRD_NRD_1	178	180	PF00675	0.620
CLV_NRD_NRD_1	188	190	PF00675	0.546
CLV_NRD_NRD_1	239	241	PF00675	0.469
CLV_NRD_NRD_1	252	254	PF00675	0.511
CLV_NRD_NRD_1	48	50	PF00675	0.721
CLV_NRD_NRD_1	94	96	PF00675	0.555
CLV_PCSK_KEX2_1	178	180	PF00082	0.640
CLV_PCSK_KEX2_1	190	192	PF00082	0.548
CLV_PCSK_KEX2_1	239	241	PF00082	0.469
CLV_PCSK_KEX2_1	252	254	PF00082	0.511
CLV_PCSK_KEX2_1	38	40	PF00082	0.727
CLV_PCSK_KEX2_1	93	95	PF00082	0.554
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.607
CLV_PCSK_PC1ET2_1	38	40	PF00082	0.712
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.619
CLV_PCSK_PC7_1	34	40	PF00082	0.684
CLV_PCSK_SKI1_1	158	162	PF00082	0.510
CLV_PCSK_SKI1_1	178	182	PF00082	0.674
CLV_PCSK_SKI1_1	191	195	PF00082	0.572
CLV_PCSK_SKI1_1	50	54	PF00082	0.638
CLV_PCSK_SKI1_1	97	101	PF00082	0.671
DEG_SPOP_SBC_1	16	20	PF00917	0.711
DEG_SPOP_SBC_1	192	196	PF00917	0.702
DEG_SPOP_SBC_1	23	27	PF00917	0.629
DOC_CKS1_1	213	218	PF01111	0.581
DOC_CYCLIN_RxL_1	152	164	PF00134	0.621
DOC_USP7_MATH_1	148	152	PF00917	0.671
DOC_USP7_MATH_1	17	21	PF00917	0.667
DOC_USP7_MATH_1	23	27	PF00917	0.612
DOC_USP7_MATH_1	42	46	PF00917	0.820
DOC_USP7_MATH_1	56	60	PF00917	0.614
DOC_USP7_MATH_1	75	79	PF00917	0.515
DOC_USP7_MATH_1	8	12	PF00917	0.715
DOC_WW_Pin1_4	212	217	PF00397	0.584
DOC_WW_Pin1_4	33	38	PF00397	0.639
LIG_14-3-3_CanoR_1	12	17	PF00244	0.659
LIG_14-3-3_CanoR_1	158	163	PF00244	0.515
LIG_14-3-3_CanoR_1	178	184	PF00244	0.546
LIG_14-3-3_CanoR_1	49	55	PF00244	0.755
LIG_14-3-3_CanoR_1	94	100	PF00244	0.562
LIG_BRCT_BRCA1_1	103	107	PF00533	0.663
LIG_Clathr_ClatBox_1	159	163	PF01394	0.537
LIG_FHA_1	140	146	PF00498	0.642
LIG_FHA_1	66	72	PF00498	0.562
LIG_FHA_1	96	102	PF00498	0.548
LIG_FHA_2	119	125	PF00498	0.548
LIG_FHA_2	159	165	PF00498	0.500
LIG_FHA_2	224	230	PF00498	0.520
LIG_FHA_2	87	93	PF00498	0.559
LIG_Pex14_2	107	111	PF04695	0.522
LIG_SH2_STAP1	168	172	PF00017	0.605
LIG_SH2_STAP1	241	245	PF00017	0.582
LIG_SH3_2	213	218	PF14604	0.715
LIG_SH3_2	80	85	PF14604	0.705
LIG_SH3_3	210	216	PF00018	0.719
LIG_SH3_3	77	83	PF00018	0.703
LIG_SUMO_SIM_par_1	158	164	PF11976	0.620
LIG_TRAF2_1	161	164	PF00917	0.478
MOD_CDK_SPK_2	33	38	PF00069	0.580
MOD_CDK_SPxK_1	212	218	PF00069	0.583
MOD_CDK_SPxK_1	33	39	PF00069	0.584
MOD_CK1_1	15	21	PF00069	0.743
MOD_CK1_1	151	157	PF00069	0.672
MOD_CK1_1	208	214	PF00069	0.744
MOD_CK1_1	22	28	PF00069	0.657
MOD_CK1_1	261	267	PF00069	0.632
MOD_CK1_1	88	94	PF00069	0.590
MOD_CK2_1	118	124	PF00069	0.566
MOD_CK2_1	158	164	PF00069	0.507
MOD_CK2_1	223	229	PF00069	0.541
MOD_CK2_1	23	29	PF00069	0.652
MOD_CK2_1	86	92	PF00069	0.569
MOD_GlcNHglycan	148	151	PF01048	0.562
MOD_GlcNHglycan	197	200	PF01048	0.691
MOD_GlcNHglycan	204	208	PF01048	0.721
MOD_GlcNHglycan	21	24	PF01048	0.604
MOD_GlcNHglycan	210	213	PF01048	0.778
MOD_GlcNHglycan	42	45	PF01048	0.777
MOD_GlcNHglycan	46	49	PF01048	0.658
MOD_GSK3_1	148	155	PF00069	0.519
MOD_GSK3_1	18	25	PF00069	0.653
MOD_GSK3_1	191	198	PF00069	0.662
MOD_GSK3_1	208	215	PF00069	0.630
MOD_GSK3_1	29	36	PF00069	0.689
MOD_GSK3_1	40	47	PF00069	0.637
MOD_GSK3_1	65	72	PF00069	0.772
MOD_GSK3_1	8	15	PF00069	0.745
MOD_GSK3_1	81	88	PF00069	0.517
MOD_NEK2_1	138	143	PF00069	0.636
MOD_PIKK_1	263	269	PF00454	0.659
MOD_PK_1	12	18	PF00069	0.711
MOD_PKA_2	65	71	PF00069	0.695
MOD_PKB_1	189	197	PF00069	0.713
MOD_Plk_4	118	124	PF00069	0.517
MOD_ProDKin_1	212	218	PF00069	0.583
MOD_ProDKin_1	33	39	PF00069	0.642
MOD_SUMO_for_1	37	40	PF00179	0.684
TRG_DiLeu_BaLyEn_6	155	160	PF01217	0.617
TRG_ER_diArg_1	177	179	PF00400	0.659
TRG_ER_diArg_1	238	240	PF00400	0.459
TRG_ER_diArg_1	94	97	PF00400	0.506
TRG_NLS_Bipartite_1	178	193	PF00514	0.667
TRG_Pf-PMV_PEXEL_1	158	163	PF00026	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4W9	Leptomonas seymouri	48%	100%
A0A3S7WXU2	Leishmania donovani	91%	100%
A4HCZ8	Leishmania braziliensis	70%	100%
A4I0I3	Leishmania infantum	91%	100%
E9AWE5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%