YceI domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

YceI-like domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4QB20_LEIMA

TriTrypDb:

LmjF.23.1320 , LMJLV39_230023300 , LMJSD75_230023700

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QB20

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QB20

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.620
CLV_NRD_NRD_1	54	56	PF00675	0.575
CLV_PCSK_KEX2_1	10	12	PF00082	0.660
CLV_PCSK_KEX2_1	54	56	PF00082	0.597
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.691
CLV_PCSK_SKI1_1	185	189	PF00082	0.654
DOC_CYCLIN_yCln2_LP_2	37	43	PF00134	0.717
DOC_MAPK_gen_1	54	64	PF00069	0.557
DOC_MAPK_gen_1	80	88	PF00069	0.589
DOC_MAPK_MEF2A_6	19	27	PF00069	0.690
DOC_MAPK_MEF2A_6	80	88	PF00069	0.614
DOC_PP1_RVXF_1	37	44	PF00149	0.554
DOC_PP2B_LxvP_1	103	106	PF13499	0.586
DOC_SPAK_OSR1_1	42	46	PF12202	0.552
DOC_USP7_MATH_1	117	121	PF00917	0.735
LIG_14-3-3_CanoR_1	11	18	PF00244	0.608
LIG_14-3-3_CanoR_1	154	162	PF00244	0.697
LIG_14-3-3_CanoR_1	83	89	PF00244	0.578
LIG_14-3-3_CanoR_1	93	101	PF00244	0.576
LIG_APCC_ABBA_1	23	28	PF00400	0.723
LIG_BIR_II_1	1	5	PF00653	0.646
LIG_FHA_1	110	116	PF00498	0.672
LIG_FHA_1	124	130	PF00498	0.546
LIG_FHA_1	173	179	PF00498	0.663
LIG_FHA_2	169	175	PF00498	0.725
LIG_LIR_Apic_2	156	161	PF02991	0.572
LIG_LIR_Gen_1	22	32	PF02991	0.678
LIG_LIR_Gen_1	79	88	PF02991	0.646
LIG_LIR_LC3C_4	146	149	PF02991	0.647
LIG_LIR_Nem_3	22	27	PF02991	0.683
LIG_LIR_Nem_3	79	84	PF02991	0.644
LIG_LIR_Nem_3	87	91	PF02991	0.649
LIG_LYPXL_yS_3	108	111	PF13949	0.622
LIG_PDZ_Class_2	184	189	PF00595	0.603
LIG_Pex14_1	166	170	PF04695	0.685
LIG_RPA_C_Fungi	50	62	PF08784	0.634
LIG_SH2_CRK	158	162	PF00017	0.633
LIG_SH2_PTP2	24	27	PF00017	0.655
LIG_SH2_SRC	24	27	PF00017	0.690
LIG_SH2_STAP1	113	117	PF00017	0.748
LIG_SH2_STAT5	101	104	PF00017	0.580
LIG_SH2_STAT5	24	27	PF00017	0.579
LIG_SH3_3	103	109	PF00018	0.615
LIG_SH3_3	146	152	PF00018	0.589
LIG_SH3_3	72	78	PF00018	0.685
LIG_SUMO_SIM_par_1	174	180	PF11976	0.648
MOD_CK1_1	13	19	PF00069	0.609
MOD_CK2_1	11	17	PF00069	0.607
MOD_CK2_1	76	82	PF00069	0.592
MOD_CK2_1	84	90	PF00069	0.555
MOD_GSK3_1	132	139	PF00069	0.693
MOD_GSK3_1	168	175	PF00069	0.651
MOD_NEK2_2	125	130	PF00069	0.592
MOD_PIKK_1	153	159	PF00454	0.662
MOD_PIKK_1	168	174	PF00454	0.652
MOD_PIKK_1	92	98	PF00454	0.489
MOD_PKA_1	10	16	PF00069	0.666
MOD_PKA_2	10	16	PF00069	0.593
MOD_PKA_2	153	159	PF00069	0.699
MOD_PKA_2	92	98	PF00069	0.528
MOD_Plk_4	65	71	PF00069	0.709
MOD_SUMO_rev_2	13	21	PF00179	0.671
TRG_DiLeu_BaEn_1	143	148	PF01217	0.572
TRG_DiLeu_BaEn_1	28	33	PF01217	0.713
TRG_DiLeu_BaLyEn_6	106	111	PF01217	0.690
TRG_ENDOCYTIC_2	108	111	PF00928	0.622
TRG_ENDOCYTIC_2	24	27	PF00928	0.681
TRG_NES_CRM1_1	17	28	PF08389	0.683

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2D1	Leptomonas seymouri	76%	100%
A0A0S4ITC1	Bodo saltans	42%	98%
A0A1X0NXE1	Trypanosomatidae	54%	100%
A0A3Q8IBN7	Leishmania donovani	94%	100%
A0A3R7LAA8	Trypanosoma rangeli	54%	100%
A4HD05	Leishmania braziliensis	87%	100%
A4I0J0	Leishmania infantum	94%	100%
C9ZVB6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	97%
E9AWF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%