Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QAZ5_LEIMA

TriTrypDb:

LmjF.23.1440 , LMJLV39_230026000 , LMJSD75_230026600

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

Q4QAZ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAZ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	170	172	PF00675	0.656
CLV_PCSK_SKI1_1	171	175	PF00082	0.617
DEG_APCC_DBOX_1	170	178	PF00400	0.250
DEG_Nend_Nbox_1	1	3	PF02207	0.621
DOC_MAPK_gen_1	171	179	PF00069	0.250
DOC_WW_Pin1_4	9	14	PF00397	0.633
LIG_14-3-3_CanoR_1	121	125	PF00244	0.604
LIG_14-3-3_CanoR_1	127	136	PF00244	0.614
LIG_14-3-3_CanoR_1	171	180	PF00244	0.250
LIG_Actin_WH2_2	107	123	PF00022	0.311
LIG_eIF4E_1	109	115	PF01652	0.339
LIG_FHA_1	111	117	PF00498	0.284
LIG_FHA_1	156	162	PF00498	0.311
LIG_GBD_Chelix_1	116	124	PF00786	0.488
LIG_LIR_Gen_1	112	120	PF02991	0.338
LIG_LIR_Gen_1	181	191	PF02991	0.325
LIG_LIR_Nem_3	102	107	PF02991	0.339
LIG_LIR_Nem_3	112	118	PF02991	0.269
LIG_LIR_Nem_3	181	186	PF02991	0.336
LIG_LIR_Nem_3	187	191	PF02991	0.294
LIG_LIR_Nem_3	50	55	PF02991	0.580
LIG_NRP_CendR_1	202	203	PF00754	0.410
LIG_Pex14_2	75	79	PF04695	0.339
LIG_Rb_LxCxE_1	131	151	PF01857	0.500
LIG_Rb_LxCxE_1	30	50	PF01857	0.652
LIG_SH2_STAT5	109	112	PF00017	0.339
LIG_SH2_STAT5	2	5	PF00017	0.619
LIG_SH2_STAT5	55	58	PF00017	0.269
LIG_Sin3_3	79	86	PF02671	0.408
LIG_SUMO_SIM_par_1	145	151	PF11976	0.339
LIG_WRC_WIRS_1	180	185	PF05994	0.325
MOD_CK1_1	131	137	PF00069	0.632
MOD_CK1_1	155	161	PF00069	0.339
MOD_CK2_1	134	140	PF00069	0.622
MOD_GlcNHglycan	29	32	PF01048	0.463
MOD_GlcNHglycan	64	67	PF01048	0.339
MOD_GSK3_1	127	134	PF00069	0.636
MOD_GSK3_1	148	155	PF00069	0.339
MOD_GSK3_1	178	185	PF00069	0.339
MOD_GSK3_1	58	65	PF00069	0.339
MOD_N-GLC_1	131	136	PF02516	0.439
MOD_NEK2_1	110	115	PF00069	0.427
MOD_NEK2_1	120	125	PF00069	0.509
MOD_NEK2_1	148	153	PF00069	0.339
MOD_NEK2_1	62	67	PF00069	0.339
MOD_NEK2_1	81	86	PF00069	0.315
MOD_NEK2_1	99	104	PF00069	0.295
MOD_PKA_2	120	126	PF00069	0.605
MOD_PKA_2	128	134	PF00069	0.603
MOD_Plk_1	131	137	PF00069	0.632
MOD_Plk_1	87	93	PF00069	0.365
MOD_Plk_4	110	116	PF00069	0.522
MOD_ProDKin_1	9	15	PF00069	0.634
TRG_ER_diArg_1	126	129	PF00400	0.678
TRG_ER_diArg_1	201	203	PF00400	0.614
TRG_NES_CRM1_1	16	27	PF08389	0.620

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WXY1	Leishmania donovani	83%	100%
A4I0L5	Leishmania infantum	85%	100%