LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QAX7_LEIMA
TriTrypDb:
LmjF.24.0030 , LMJLV39_240005600 * , LMJSD75_240005300
Length:
166

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QAX7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAX7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 106 108 PF00675 0.380
CLV_NRD_NRD_1 129 131 PF00675 0.582
CLV_NRD_NRD_1 145 147 PF00675 0.416
CLV_NRD_NRD_1 164 166 PF00675 0.654
CLV_NRD_NRD_1 46 48 PF00675 0.609
CLV_PCSK_KEX2_1 137 139 PF00082 0.485
CLV_PCSK_KEX2_1 145 147 PF00082 0.549
CLV_PCSK_KEX2_1 46 48 PF00082 0.561
CLV_PCSK_PC1ET2_1 137 139 PF00082 0.485
CLV_PCSK_SKI1_1 58 62 PF00082 0.370
CLV_PCSK_SKI1_1 84 88 PF00082 0.370
DEG_APCC_KENBOX_2 107 111 PF00400 0.397
DEG_Nend_UBRbox_1 1 4 PF02207 0.480
DOC_MAPK_gen_1 107 114 PF00069 0.382
DOC_USP7_MATH_1 95 99 PF00917 0.405
DOC_USP7_UBL2_3 133 137 PF12436 0.514
DOC_WW_Pin1_4 154 159 PF00397 0.517
LIG_14-3-3_CanoR_1 152 157 PF00244 0.566
LIG_14-3-3_CanoR_1 58 66 PF00244 0.424
LIG_14-3-3_CanoR_1 7 13 PF00244 0.472
LIG_BRCT_BRCA1_1 100 104 PF00533 0.404
LIG_LIR_Nem_3 101 106 PF02991 0.356
LIG_LIR_Nem_3 61 66 PF02991 0.426
LIG_LIR_Nem_3 68 72 PF02991 0.350
LIG_MLH1_MIPbox_1 100 104 PF16413 0.404
LIG_REV1ctd_RIR_1 101 112 PF16727 0.375
LIG_SH2_CRK 90 94 PF00017 0.386
LIG_SH2_STAT3 21 24 PF00017 0.546
LIG_SH3_1 47 53 PF00018 0.481
LIG_SH3_2 41 46 PF14604 0.548
LIG_SH3_3 36 42 PF00018 0.768
LIG_SH3_3 47 53 PF00018 0.403
LIG_TYR_ITIM 88 93 PF00017 0.404
LIG_WRC_WIRS_1 66 71 PF05994 0.378
MOD_CK1_1 8 14 PF00069 0.477
MOD_CK1_1 98 104 PF00069 0.390
MOD_DYRK1A_RPxSP_1 154 158 PF00069 0.521
MOD_GlcNHglycan 117 120 PF01048 0.415
MOD_GlcNHglycan 97 100 PF01048 0.375
MOD_GSK3_1 148 155 PF00069 0.516
MOD_PIKK_1 156 162 PF00454 0.491
MOD_Plk_4 65 71 PF00069 0.385
MOD_ProDKin_1 154 160 PF00069 0.520
MOD_SUMO_rev_2 129 139 PF00179 0.508
TRG_DiLeu_BaLyEn_6 55 60 PF01217 0.366
TRG_ENDOCYTIC_2 90 93 PF00928 0.391

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WXZ3 Leishmania donovani 91% 100%
A0A422P424 Trypanosoma rangeli 40% 100%
A4HD61 Leishmania braziliensis 80% 100%
A4I0M6 Leishmania infantum 91% 100%
D0A6X4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 95%
E9AWJ3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS