Peptidase S59 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QAP3_LEIMA

TriTrypDb:

LmjF.24.0900 , LMJLV39_240014800 , LMJSD75_240014300

Length:

1254

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005643	nuclear pore	3	2
GO:0005737	cytoplasm	2	2
GO:0032991	protein-containing complex	1	2
GO:0070390	transcription export complex 2	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0140513	nuclear protein-containing complex	2	2

Expansion

Sequence features

Q4QAP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAP3

Function

Biological processes
Term	Name	Level	Count
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	6	2
GO:0000973	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery	7	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006354	DNA-templated transcription elongation	6	2
GO:0006368	transcription elongation by RNA polymerase II	7	2
GO:0006405	RNA export from nucleus	5	6
GO:0006406	mRNA export from nucleus	6	6
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0006810	transport	3	6
GO:0006913	nucleocytoplasmic transport	5	6
GO:0006996	organelle organization	4	2
GO:0008152	metabolic process	1	2
GO:0009058	biosynthetic process	2	2
GO:0009059	macromolecule biosynthetic process	4	2
GO:0009987	cellular process	1	6
GO:0015931	nucleobase-containing compound transport	5	6
GO:0016043	cellular component organization	3	2
GO:0016070	RNA metabolic process	5	2
GO:0016973	poly(A)+ mRNA export from nucleus	7	6
GO:0018130	heterocycle biosynthetic process	4	2
GO:0019438	aromatic compound biosynthetic process	4	2
GO:0032774	RNA biosynthetic process	5	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034654	nucleobase-containing compound biosynthetic process	4	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044249	cellular biosynthetic process	3	2
GO:0044271	cellular nitrogen compound biosynthetic process	4	2
GO:0046483	heterocycle metabolic process	3	2
GO:0046907	intracellular transport	3	6
GO:0050657	nucleic acid transport	6	6
GO:0050658	RNA transport	4	6
GO:0051028	mRNA transport	5	6
GO:0051168	nuclear export	6	6
GO:0051169	nuclear transport	4	6
GO:0051179	localization	1	6
GO:0051234	establishment of localization	2	6
GO:0051236	establishment of RNA localization	3	6
GO:0051276	chromosome organization	5	2
GO:0051641	cellular localization	2	6
GO:0051649	establishment of localization in cell	3	6
GO:0071702	organic substance transport	4	6
GO:0071704	organic substance metabolic process	2	2
GO:0071705	nitrogen compound transport	4	6
GO:0071840	cellular component organization or biogenesis	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901362	organic cyclic compound biosynthetic process	4	2
GO:1901576	organic substance biosynthetic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003677	DNA binding	4	2
GO:0003690	double-stranded DNA binding	5	2
GO:0003723	RNA binding	4	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1204	1208	PF00656	0.451
CLV_C14_Caspase3-7	1246	1250	PF00656	0.467
CLV_C14_Caspase3-7	383	387	PF00656	0.571
CLV_C14_Caspase3-7	663	667	PF00656	0.680
CLV_NRD_NRD_1	1061	1063	PF00675	0.377
CLV_NRD_NRD_1	1099	1101	PF00675	0.418
CLV_NRD_NRD_1	678	680	PF00675	0.726
CLV_NRD_NRD_1	685	687	PF00675	0.658
CLV_NRD_NRD_1	726	728	PF00675	0.622
CLV_NRD_NRD_1	950	952	PF00675	0.478
CLV_NRD_NRD_1	984	986	PF00675	0.528
CLV_PCSK_KEX2_1	1061	1063	PF00082	0.377
CLV_PCSK_KEX2_1	1099	1101	PF00082	0.418
CLV_PCSK_KEX2_1	677	679	PF00082	0.726
CLV_PCSK_KEX2_1	685	687	PF00082	0.648
CLV_PCSK_KEX2_1	726	728	PF00082	0.622
CLV_PCSK_KEX2_1	950	952	PF00082	0.478
CLV_PCSK_KEX2_1	984	986	PF00082	0.528
CLV_PCSK_PC7_1	681	687	PF00082	0.670
CLV_PCSK_SKI1_1	1002	1006	PF00082	0.509
CLV_PCSK_SKI1_1	1055	1059	PF00082	0.425
CLV_PCSK_SKI1_1	1099	1103	PF00082	0.447
CLV_PCSK_SKI1_1	1171	1175	PF00082	0.493
CLV_PCSK_SKI1_1	172	176	PF00082	0.667
CLV_PCSK_SKI1_1	602	606	PF00082	0.623
CLV_PCSK_SKI1_1	772	776	PF00082	0.558
CLV_PCSK_SKI1_1	953	957	PF00082	0.506
CLV_PCSK_SKI1_1	984	988	PF00082	0.582
CLV_Separin_Metazoa	1194	1198	PF03568	0.452
DEG_APCC_DBOX_1	1099	1107	PF00400	0.432
DEG_APCC_DBOX_1	1168	1176	PF00400	0.513
DEG_COP1_1	421	429	PF00400	0.540
DEG_SCF_FBW7_1	317	324	PF00400	0.648
DEG_SCF_FBW7_1	378	385	PF00400	0.645
DEG_SPOP_SBC_1	316	320	PF00917	0.655
DEG_SPOP_SBC_1	560	564	PF00917	0.564
DEG_SPOP_SBC_1	886	890	PF00917	0.652
DOC_ANK_TNKS_1	685	692	PF00023	0.626
DOC_CKS1_1	323	328	PF01111	0.622
DOC_CKS1_1	379	384	PF01111	0.650
DOC_CKS1_1	447	452	PF01111	0.554
DOC_CKS1_1	994	999	PF01111	0.602
DOC_CYCLIN_RxL_1	999	1009	PF00134	0.574
DOC_CYCLIN_yCln2_LP_2	1067	1073	PF00134	0.481
DOC_CYCLIN_yCln2_LP_2	96	102	PF00134	0.544
DOC_MAPK_gen_1	1099	1106	PF00069	0.387
DOC_MAPK_gen_1	1169	1178	PF00069	0.421
DOC_MAPK_gen_1	769	778	PF00069	0.571
DOC_MAPK_MEF2A_6	1033	1041	PF00069	0.426
DOC_MAPK_MEF2A_6	1099	1106	PF00069	0.387
DOC_MAPK_MEF2A_6	1169	1176	PF00069	0.425
DOC_MAPK_NFAT4_5	1169	1177	PF00069	0.422
DOC_MAPK_RevD_3	1086	1100	PF00069	0.381
DOC_PP1_RVXF_1	57	63	PF00149	0.469
DOC_PP2B_LxvP_1	1125	1128	PF13499	0.478
DOC_PP2B_LxvP_1	720	723	PF13499	0.632
DOC_PP2B_LxvP_1	752	755	PF13499	0.672
DOC_PP2B_PxIxI_1	1128	1134	PF00149	0.347
DOC_PP4_FxxP_1	265	268	PF00568	0.668
DOC_PP4_FxxP_1	460	463	PF00568	0.534
DOC_PP4_FxxP_1	536	539	PF00568	0.665
DOC_SPAK_OSR1_1	129	133	PF12202	0.522
DOC_USP7_MATH_1	165	169	PF00917	0.678
DOC_USP7_MATH_1	237	241	PF00917	0.635
DOC_USP7_MATH_1	261	265	PF00917	0.575
DOC_USP7_MATH_1	297	301	PF00917	0.701
DOC_USP7_MATH_1	316	320	PF00917	0.535
DOC_USP7_MATH_1	382	386	PF00917	0.648
DOC_USP7_MATH_1	427	431	PF00917	0.585
DOC_USP7_MATH_1	522	526	PF00917	0.639
DOC_USP7_MATH_1	561	565	PF00917	0.636
DOC_USP7_MATH_1	638	642	PF00917	0.671
DOC_USP7_MATH_1	655	659	PF00917	0.567
DOC_USP7_MATH_1	660	664	PF00917	0.687
DOC_USP7_MATH_1	702	706	PF00917	0.702
DOC_USP7_MATH_1	711	715	PF00917	0.649
DOC_USP7_MATH_1	732	736	PF00917	0.729
DOC_USP7_MATH_1	77	81	PF00917	0.615
DOC_USP7_MATH_1	791	795	PF00917	0.616
DOC_USP7_MATH_1	876	880	PF00917	0.465
DOC_USP7_MATH_1	886	890	PF00917	0.623
DOC_USP7_MATH_1	891	895	PF00917	0.520
DOC_WW_Pin1_4	1234	1239	PF00397	0.425
DOC_WW_Pin1_4	135	140	PF00397	0.611
DOC_WW_Pin1_4	201	206	PF00397	0.634
DOC_WW_Pin1_4	221	226	PF00397	0.482
DOC_WW_Pin1_4	25	30	PF00397	0.456
DOC_WW_Pin1_4	317	322	PF00397	0.650
DOC_WW_Pin1_4	35	40	PF00397	0.478
DOC_WW_Pin1_4	378	383	PF00397	0.645
DOC_WW_Pin1_4	439	444	PF00397	0.614
DOC_WW_Pin1_4	446	451	PF00397	0.564
DOC_WW_Pin1_4	506	511	PF00397	0.644
DOC_WW_Pin1_4	52	57	PF00397	0.500
DOC_WW_Pin1_4	552	557	PF00397	0.605
DOC_WW_Pin1_4	563	568	PF00397	0.574
DOC_WW_Pin1_4	585	590	PF00397	0.673
DOC_WW_Pin1_4	630	635	PF00397	0.657
DOC_WW_Pin1_4	709	714	PF00397	0.700
DOC_WW_Pin1_4	993	998	PF00397	0.632
LIG_14-3-3_CanoR_1	1002	1008	PF00244	0.539
LIG_14-3-3_CanoR_1	1072	1076	PF00244	0.416
LIG_14-3-3_CanoR_1	1189	1198	PF00244	0.585
LIG_14-3-3_CanoR_1	59	63	PF00244	0.480
LIG_14-3-3_CanoR_1	602	610	PF00244	0.561
LIG_14-3-3_CanoR_1	678	684	PF00244	0.696
LIG_14-3-3_CanoR_1	769	775	PF00244	0.565
LIG_14-3-3_CanoR_1	950	956	PF00244	0.518
LIG_14-3-3_CanoR_1	962	968	PF00244	0.445
LIG_14-3-3_CanoR_1	984	994	PF00244	0.593
LIG_BIR_III_2	1240	1244	PF00653	0.465
LIG_BIR_III_2	938	942	PF00653	0.542
LIG_BIR_III_4	386	390	PF00653	0.652
LIG_BIR_III_4	407	411	PF00653	0.594
LIG_BRCT_BRCA1_1	418	422	PF00533	0.687
LIG_BRCT_BRCA1_1	481	485	PF00533	0.659
LIG_BRCT_BRCA1_1	54	58	PF00533	0.513
LIG_BRCT_BRCA1_1	975	979	PF00533	0.502
LIG_deltaCOP1_diTrp_1	858	864	PF00928	0.478
LIG_EH_1	97	101	PF12763	0.544
LIG_EH1_1	1020	1028	PF00400	0.457
LIG_EVH1_1	752	756	PF00568	0.624
LIG_FHA_1	1137	1143	PF00498	0.398
LIG_FHA_1	121	127	PF00498	0.618
LIG_FHA_1	155	161	PF00498	0.552
LIG_FHA_1	184	190	PF00498	0.541
LIG_FHA_1	221	227	PF00498	0.600
LIG_FHA_1	312	318	PF00498	0.702
LIG_FHA_1	323	329	PF00498	0.595
LIG_FHA_1	908	914	PF00498	0.514
LIG_FHA_1	973	979	PF00498	0.503
LIG_FHA_1	986	992	PF00498	0.482
LIG_FHA_2	1235	1241	PF00498	0.459
LIG_FHA_2	1244	1250	PF00498	0.510
LIG_FHA_2	416	422	PF00498	0.556
LIG_FHA_2	822	828	PF00498	0.565
LIG_FHA_2	994	1000	PF00498	0.635
LIG_GBD_Chelix_1	1103	1111	PF00786	0.414
LIG_HCF-1_HBM_1	1227	1230	PF13415	0.474
LIG_IRF3_LxIS_1	1037	1042	PF10401	0.481
LIG_LIR_Apic_2	263	268	PF02991	0.660
LIG_LIR_Apic_2	458	463	PF02991	0.524
LIG_LIR_Apic_2	534	539	PF02991	0.670
LIG_LIR_Gen_1	1018	1029	PF02991	0.460
LIG_LIR_Gen_1	1119	1130	PF02991	0.488
LIG_LIR_Gen_1	1200	1211	PF02991	0.463
LIG_LIR_Gen_1	1227	1238	PF02991	0.522
LIG_LIR_Gen_1	527	536	PF02991	0.556
LIG_LIR_Gen_1	858	866	PF02991	0.473
LIG_LIR_Gen_1	976	986	PF02991	0.511
LIG_LIR_Nem_3	1018	1024	PF02991	0.589
LIG_LIR_Nem_3	1119	1125	PF02991	0.509
LIG_LIR_Nem_3	1200	1206	PF02991	0.458
LIG_LIR_Nem_3	1227	1233	PF02991	0.509
LIG_LIR_Nem_3	1237	1242	PF02991	0.482
LIG_LIR_Nem_3	136	140	PF02991	0.655
LIG_LIR_Nem_3	394	399	PF02991	0.636
LIG_LIR_Nem_3	527	532	PF02991	0.665
LIG_LIR_Nem_3	61	65	PF02991	0.525
LIG_LIR_Nem_3	70	74	PF02991	0.591
LIG_LIR_Nem_3	805	811	PF02991	0.536
LIG_LIR_Nem_3	858	863	PF02991	0.478
LIG_LIR_Nem_3	976	982	PF02991	0.505
LIG_MYND_1	371	375	PF01753	0.614
LIG_MYND_1	413	417	PF01753	0.606
LIG_NRBOX	1102	1108	PF00104	0.414
LIG_NRBOX	32	38	PF00104	0.489
LIG_NRBOX	922	928	PF00104	0.595
LIG_OCRL_FandH_1	528	540	PF00620	0.622
LIG_Pex14_1	1003	1007	PF04695	0.575
LIG_Pex14_1	860	864	PF04695	0.471
LIG_Pex14_2	100	104	PF04695	0.536
LIG_Pex14_2	1040	1044	PF04695	0.459
LIG_Pex14_2	58	62	PF04695	0.498
LIG_Pex14_2	65	69	PF04695	0.486
LIG_RPA_C_Fungi	1057	1069	PF08784	0.386
LIG_SH2_CRK	1198	1202	PF00017	0.467
LIG_SH2_CRK	942	946	PF00017	0.510
LIG_SH2_GRB2like	869	872	PF00017	0.451
LIG_SH2_GRB2like	919	922	PF00017	0.474
LIG_SH2_NCK_1	1203	1207	PF00017	0.461
LIG_SH2_NCK_1	942	946	PF00017	0.510
LIG_SH2_SRC	1021	1024	PF00017	0.405
LIG_SH2_STAP1	919	923	PF00017	0.469
LIG_SH2_STAT5	1021	1024	PF00017	0.604
LIG_SH2_STAT5	1181	1184	PF00017	0.560
LIG_SH2_STAT5	1230	1233	PF00017	0.430
LIG_SH2_STAT5	869	872	PF00017	0.534
LIG_SH3_1	340	346	PF00018	0.606
LIG_SH3_3	1085	1091	PF00018	0.455
LIG_SH3_3	144	150	PF00018	0.658
LIG_SH3_3	164	170	PF00018	0.631
LIG_SH3_3	204	210	PF00018	0.624
LIG_SH3_3	212	218	PF00018	0.559
LIG_SH3_3	289	295	PF00018	0.716
LIG_SH3_3	320	326	PF00018	0.622
LIG_SH3_3	340	346	PF00018	0.501
LIG_SH3_3	368	374	PF00018	0.649
LIG_SH3_3	410	416	PF00018	0.676
LIG_SH3_3	495	501	PF00018	0.607
LIG_SH3_3	553	559	PF00018	0.582
LIG_SH3_3	586	592	PF00018	0.671
LIG_SH3_3	632	638	PF00018	0.625
LIG_SH3_3	648	654	PF00018	0.549
LIG_SH3_3	696	702	PF00018	0.710
LIG_SH3_3	750	756	PF00018	0.629
LIG_SUMO_SIM_anti_2	1139	1147	PF11976	0.405
LIG_SUMO_SIM_anti_2	744	750	PF11976	0.566
LIG_SUMO_SIM_par_1	1214	1219	PF11976	0.455
LIG_SUMO_SIM_par_1	32	38	PF11976	0.489
LIG_TRAF2_1	795	798	PF00917	0.591
LIG_TYR_ITIM	1196	1201	PF00017	0.457
LIG_UBA3_1	1213	1220	PF00899	0.449
LIG_UBA3_1	873	881	PF00899	0.516
LIG_UBA3_1	978	987	PF00899	0.643
LIG_WRC_WIRS_1	1016	1021	PF05994	0.465
LIG_WRC_WIRS_1	68	73	PF05994	0.608
LIG_WW_2	413	416	PF00397	0.589
LIG_WW_2	755	758	PF00397	0.645
MOD_CDK_SPxK_1	630	636	PF00069	0.658
MOD_CDK_SPxxK_3	52	59	PF00069	0.485
MOD_CK1_1	1188	1194	PF00069	0.393
MOD_CK1_1	120	126	PF00069	0.629
MOD_CK1_1	1234	1240	PF00069	0.490
MOD_CK1_1	198	204	PF00069	0.653
MOD_CK1_1	220	226	PF00069	0.601
MOD_CK1_1	256	262	PF00069	0.616
MOD_CK1_1	276	282	PF00069	0.569
MOD_CK1_1	290	296	PF00069	0.616
MOD_CK1_1	304	310	PF00069	0.607
MOD_CK1_1	315	321	PF00069	0.594
MOD_CK1_1	359	365	PF00069	0.647
MOD_CK1_1	425	431	PF00069	0.619
MOD_CK1_1	488	494	PF00069	0.566
MOD_CK1_1	502	508	PF00069	0.580
MOD_CK1_1	527	533	PF00069	0.576
MOD_CK1_1	593	599	PF00069	0.630
MOD_CK1_1	612	618	PF00069	0.551
MOD_CK1_1	625	631	PF00069	0.578
MOD_CK1_1	645	651	PF00069	0.544
MOD_CK1_1	658	664	PF00069	0.587
MOD_CK1_1	70	76	PF00069	0.588
MOD_CK1_1	879	885	PF00069	0.755
MOD_CK1_1	889	895	PF00069	0.610
MOD_CK2_1	1071	1077	PF00069	0.465
MOD_CK2_1	1188	1194	PF00069	0.393
MOD_CK2_1	290	296	PF00069	0.646
MOD_CK2_1	715	721	PF00069	0.656
MOD_CK2_1	791	797	PF00069	0.610
MOD_CK2_1	821	827	PF00069	0.562
MOD_CK2_1	993	999	PF00069	0.674
MOD_Cter_Amidation	675	678	PF01082	0.697
MOD_DYRK1A_RPxSP_1	52	56	PF00069	0.524
MOD_GlcNHglycan	1041	1044	PF01048	0.462
MOD_GlcNHglycan	1049	1052	PF01048	0.483
MOD_GlcNHglycan	113	116	PF01048	0.647
MOD_GlcNHglycan	119	122	PF01048	0.587
MOD_GlcNHglycan	1233	1236	PF01048	0.552
MOD_GlcNHglycan	167	170	PF01048	0.673
MOD_GlcNHglycan	177	180	PF01048	0.568
MOD_GlcNHglycan	192	195	PF01048	0.525
MOD_GlcNHglycan	200	203	PF01048	0.567
MOD_GlcNHglycan	226	229	PF01048	0.658
MOD_GlcNHglycan	244	247	PF01048	0.650
MOD_GlcNHglycan	255	258	PF01048	0.573
MOD_GlcNHglycan	275	278	PF01048	0.567
MOD_GlcNHglycan	281	284	PF01048	0.639
MOD_GlcNHglycan	314	317	PF01048	0.706
MOD_GlcNHglycan	331	334	PF01048	0.548
MOD_GlcNHglycan	336	339	PF01048	0.612
MOD_GlcNHglycan	353	356	PF01048	0.602
MOD_GlcNHglycan	361	364	PF01048	0.627
MOD_GlcNHglycan	382	385	PF01048	0.614
MOD_GlcNHglycan	393	396	PF01048	0.586
MOD_GlcNHglycan	401	404	PF01048	0.579
MOD_GlcNHglycan	429	432	PF01048	0.650
MOD_GlcNHglycan	482	485	PF01048	0.562
MOD_GlcNHglycan	501	504	PF01048	0.504
MOD_GlcNHglycan	524	527	PF01048	0.618
MOD_GlcNHglycan	548	551	PF01048	0.618
MOD_GlcNHglycan	563	566	PF01048	0.560
MOD_GlcNHglycan	595	598	PF01048	0.651
MOD_GlcNHglycan	611	614	PF01048	0.578
MOD_GlcNHglycan	644	647	PF01048	0.684
MOD_GlcNHglycan	660	663	PF01048	0.612
MOD_GlcNHglycan	681	684	PF01048	0.636
MOD_GlcNHglycan	692	696	PF01048	0.673
MOD_GlcNHglycan	713	716	PF01048	0.776
MOD_GlcNHglycan	734	737	PF01048	0.637
MOD_GlcNHglycan	779	782	PF01048	0.552
MOD_GlcNHglycan	79	82	PF01048	0.672
MOD_GlcNHglycan	840	843	PF01048	0.666
MOD_GlcNHglycan	846	849	PF01048	0.714
MOD_GlcNHglycan	852	855	PF01048	0.554
MOD_GlcNHglycan	874	877	PF01048	0.441
MOD_GlcNHglycan	881	884	PF01048	0.598
MOD_GlcNHglycan	889	892	PF01048	0.571
MOD_GlcNHglycan	988	991	PF01048	0.757
MOD_GSK3_1	1011	1018	PF00069	0.545
MOD_GSK3_1	116	123	PF00069	0.661
MOD_GSK3_1	1197	1204	PF00069	0.351
MOD_GSK3_1	197	204	PF00069	0.636
MOD_GSK3_1	217	224	PF00069	0.485
MOD_GSK3_1	252	259	PF00069	0.587
MOD_GSK3_1	272	279	PF00069	0.585
MOD_GSK3_1	297	304	PF00069	0.714
MOD_GSK3_1	311	318	PF00069	0.579
MOD_GSK3_1	347	354	PF00069	0.637
MOD_GSK3_1	378	385	PF00069	0.626
MOD_GSK3_1	421	428	PF00069	0.615
MOD_GSK3_1	502	509	PF00069	0.617
MOD_GSK3_1	527	534	PF00069	0.579
MOD_GSK3_1	559	566	PF00069	0.629
MOD_GSK3_1	581	588	PF00069	0.678
MOD_GSK3_1	605	612	PF00069	0.622
MOD_GSK3_1	638	645	PF00069	0.686
MOD_GSK3_1	654	661	PF00069	0.572
MOD_GSK3_1	703	710	PF00069	0.762
MOD_GSK3_1	711	718	PF00069	0.701
MOD_GSK3_1	732	739	PF00069	0.667
MOD_GSK3_1	838	845	PF00069	0.742
MOD_GSK3_1	865	872	PF00069	0.542
MOD_GSK3_1	885	892	PF00069	0.646
MOD_GSK3_1	907	914	PF00069	0.519
MOD_GSK3_1	966	973	PF00069	0.544
MOD_N-GLC_1	121	126	PF02516	0.597
MOD_N-GLC_1	165	170	PF02516	0.644
MOD_N-GLC_1	261	266	PF02516	0.618
MOD_N-GLC_1	356	361	PF02516	0.633
MOD_N-GLC_1	522	527	PF02516	0.666
MOD_NEK2_1	1015	1020	PF00069	0.523
MOD_NEK2_1	1039	1044	PF00069	0.469
MOD_NEK2_1	1071	1076	PF00069	0.464
MOD_NEK2_1	1137	1142	PF00069	0.402
MOD_NEK2_1	1144	1149	PF00069	0.342
MOD_NEK2_1	1180	1185	PF00069	0.454
MOD_NEK2_1	1231	1236	PF00069	0.606
MOD_NEK2_1	177	182	PF00069	0.615
MOD_NEK2_1	190	195	PF00069	0.525
MOD_NEK2_1	197	202	PF00069	0.488
MOD_NEK2_1	311	316	PF00069	0.656
MOD_NEK2_1	422	427	PF00069	0.656
MOD_NEK2_1	445	450	PF00069	0.556
MOD_NEK2_1	485	490	PF00069	0.660
MOD_NEK2_1	532	537	PF00069	0.680
MOD_NEK2_1	58	63	PF00069	0.505
MOD_NEK2_1	642	647	PF00069	0.700
MOD_NEK2_1	707	712	PF00069	0.743
MOD_NEK2_1	821	826	PF00069	0.559
MOD_NEK2_1	877	882	PF00069	0.580
MOD_NEK2_1	9	14	PF00069	0.477
MOD_NEK2_2	154	159	PF00069	0.600
MOD_NEK2_2	622	627	PF00069	0.636
MOD_PIKK_1	141	147	PF00454	0.637
MOD_PIKK_1	301	307	PF00454	0.718
MOD_PIKK_1	736	742	PF00454	0.661
MOD_PIKK_1	842	848	PF00454	0.613
MOD_PK_1	524	530	PF00069	0.666
MOD_PK_1	951	957	PF00069	0.472
MOD_PKA_2	1071	1077	PF00069	0.418
MOD_PKA_2	1188	1194	PF00069	0.393
MOD_PKA_2	273	279	PF00069	0.642
MOD_PKA_2	290	296	PF00069	0.597
MOD_PKA_2	329	335	PF00069	0.629
MOD_PKA_2	58	64	PF00069	0.468
MOD_PKA_2	842	848	PF00069	0.660
MOD_PKB_1	677	685	PF00069	0.721
MOD_Plk_1	121	127	PF00069	0.595
MOD_Plk_1	261	267	PF00069	0.618
MOD_Plk_1	422	428	PF00069	0.538
MOD_Plk_1	896	902	PF00069	0.432
MOD_Plk_4	1011	1017	PF00069	0.460
MOD_Plk_4	1071	1077	PF00069	0.474
MOD_Plk_4	1084	1090	PF00069	0.342
MOD_Plk_4	121	127	PF00069	0.572
MOD_Plk_4	455	461	PF00069	0.602
MOD_Plk_4	485	491	PF00069	0.650
MOD_Plk_4	524	530	PF00069	0.666
MOD_Plk_4	58	64	PF00069	0.480
MOD_Plk_4	605	611	PF00069	0.600
MOD_Plk_4	622	628	PF00069	0.614
MOD_Plk_4	744	750	PF00069	0.566
MOD_Plk_4	770	776	PF00069	0.561
MOD_Plk_4	865	871	PF00069	0.527
MOD_Plk_4	940	946	PF00069	0.483
MOD_ProDKin_1	1234	1240	PF00069	0.430
MOD_ProDKin_1	135	141	PF00069	0.613
MOD_ProDKin_1	201	207	PF00069	0.635
MOD_ProDKin_1	221	227	PF00069	0.483
MOD_ProDKin_1	25	31	PF00069	0.451
MOD_ProDKin_1	317	323	PF00069	0.647
MOD_ProDKin_1	35	41	PF00069	0.476
MOD_ProDKin_1	378	384	PF00069	0.646
MOD_ProDKin_1	439	445	PF00069	0.615
MOD_ProDKin_1	446	452	PF00069	0.564
MOD_ProDKin_1	506	512	PF00069	0.645
MOD_ProDKin_1	52	58	PF00069	0.500
MOD_ProDKin_1	552	558	PF00069	0.607
MOD_ProDKin_1	563	569	PF00069	0.579
MOD_ProDKin_1	585	591	PF00069	0.674
MOD_ProDKin_1	630	636	PF00069	0.658
MOD_ProDKin_1	709	715	PF00069	0.699
MOD_ProDKin_1	993	999	PF00069	0.628
MOD_SUMO_rev_2	350	359	PF00179	0.592
MOD_SUMO_rev_2	383	390	PF00179	0.626
MOD_SUMO_rev_2	760	764	PF00179	0.615
TRG_DiLeu_BaEn_1	1011	1016	PF01217	0.509
TRG_DiLeu_BaEn_1	1078	1083	PF01217	0.431
TRG_DiLeu_BaEn_1	922	927	PF01217	0.470
TRG_DiLeu_BaLyEn_6	1126	1131	PF01217	0.341
TRG_DiLeu_BaLyEn_6	1212	1217	PF01217	0.424
TRG_DiLeu_BaLyEn_6	192	197	PF01217	0.587
TRG_DiLeu_BaLyEn_6	28	33	PF01217	0.458
TRG_DiLeu_BaLyEn_6	81	86	PF01217	0.637
TRG_ENDOCYTIC_2	1021	1024	PF00928	0.604
TRG_ENDOCYTIC_2	1198	1201	PF00928	0.609
TRG_ENDOCYTIC_2	1203	1206	PF00928	0.531
TRG_ENDOCYTIC_2	1230	1233	PF00928	0.430
TRG_ENDOCYTIC_2	137	140	PF00928	0.612
TRG_ENDOCYTIC_2	942	945	PF00928	0.513
TRG_ER_diArg_1	1060	1062	PF00400	0.377
TRG_ER_diArg_1	1099	1101	PF00400	0.418
TRG_ER_diArg_1	1169	1172	PF00400	0.527
TRG_ER_diArg_1	677	679	PF00400	0.726
TRG_ER_diArg_1	684	686	PF00400	0.655
TRG_ER_diArg_1	725	727	PF00400	0.612
TRG_ER_diArg_1	949	951	PF00400	0.485
TRG_ER_diArg_1	984	986	PF00400	0.528
TRG_NES_CRM1_1	1013	1025	PF08389	0.469

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WY79	Leishmania donovani	89%	100%
A4HDE6	Leishmania braziliensis	66%	100%
A4I0S9	Leishmania infantum	88%	100%
E9AWT1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	95%