Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QAL6_LEIMA

TriTrypDb:

LmjF.24.1160 , LMJLV39_240017700 , LMJSD75_240017200

Length:

1047

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QAL6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAL6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	265	269	PF00656	0.594
CLV_C14_Caspase3-7	521	525	PF00656	0.527
CLV_C14_Caspase3-7	738	742	PF00656	0.640
CLV_C14_Caspase3-7	799	803	PF00656	0.624
CLV_C14_Caspase3-7	993	997	PF00656	0.556
CLV_NRD_NRD_1	152	154	PF00675	0.471
CLV_NRD_NRD_1	250	252	PF00675	0.631
CLV_NRD_NRD_1	274	276	PF00675	0.538
CLV_NRD_NRD_1	345	347	PF00675	0.524
CLV_NRD_NRD_1	616	618	PF00675	0.650
CLV_NRD_NRD_1	951	953	PF00675	0.540
CLV_NRD_NRD_1	955	957	PF00675	0.509
CLV_PCSK_FUR_1	952	956	PF00082	0.540
CLV_PCSK_KEX2_1	1028	1030	PF00082	0.639
CLV_PCSK_KEX2_1	152	154	PF00082	0.471
CLV_PCSK_KEX2_1	250	252	PF00082	0.631
CLV_PCSK_KEX2_1	274	276	PF00082	0.548
CLV_PCSK_KEX2_1	344	346	PF00082	0.519
CLV_PCSK_KEX2_1	616	618	PF00082	0.671
CLV_PCSK_KEX2_1	951	953	PF00082	0.540
CLV_PCSK_KEX2_1	954	956	PF00082	0.511
CLV_PCSK_PC1ET2_1	1028	1030	PF00082	0.639
CLV_PCSK_PC1ET2_1	344	346	PF00082	0.496
CLV_PCSK_PC7_1	951	957	PF00082	0.540
CLV_PCSK_SKI1_1	102	106	PF00082	0.563
CLV_PCSK_SKI1_1	20	24	PF00082	0.656
CLV_PCSK_SKI1_1	453	457	PF00082	0.590
CLV_PCSK_SKI1_1	478	482	PF00082	0.564
CLV_PCSK_SKI1_1	64	68	PF00082	0.680
CLV_PCSK_SKI1_1	838	842	PF00082	0.679
CLV_PCSK_SKI1_1	927	931	PF00082	0.536
DEG_APCC_DBOX_1	15	23	PF00400	0.664
DEG_APCC_DBOX_1	327	335	PF00400	0.533
DEG_APCC_DBOX_1	918	926	PF00400	0.464
DEG_Nend_UBRbox_3	1	3	PF02207	0.679
DEG_SPOP_SBC_1	175	179	PF00917	0.633
DEG_SPOP_SBC_1	696	700	PF00917	0.666
DEG_SPOP_SBC_1	718	722	PF00917	0.599
DEG_SPOP_SBC_1	848	852	PF00917	0.623
DOC_CKS1_1	33	38	PF01111	0.638
DOC_CYCLIN_RxL_1	643	653	PF00134	0.640
DOC_CYCLIN_RxL_1	753	766	PF00134	0.678
DOC_CYCLIN_yCln2_LP_2	33	39	PF00134	0.541
DOC_MAPK_gen_1	511	518	PF00069	0.536
DOC_MAPK_gen_1	954	963	PF00069	0.551
DOC_PP2B_LxvP_1	871	874	PF13499	0.658
DOC_PP4_FxxP_1	66	69	PF00568	0.674
DOC_USP7_MATH_1	12	16	PF00917	0.672
DOC_USP7_MATH_1	168	172	PF00917	0.611
DOC_USP7_MATH_1	173	177	PF00917	0.609
DOC_USP7_MATH_1	224	228	PF00917	0.665
DOC_USP7_MATH_1	244	248	PF00917	0.731
DOC_USP7_MATH_1	288	292	PF00917	0.567
DOC_USP7_MATH_1	41	45	PF00917	0.627
DOC_USP7_MATH_1	451	455	PF00917	0.484
DOC_USP7_MATH_1	467	471	PF00917	0.398
DOC_USP7_MATH_1	483	487	PF00917	0.379
DOC_USP7_MATH_1	573	577	PF00917	0.600
DOC_USP7_MATH_1	686	690	PF00917	0.605
DOC_USP7_MATH_1	719	723	PF00917	0.600
DOC_USP7_MATH_1	77	81	PF00917	0.779
DOC_USP7_MATH_1	791	795	PF00917	0.578
DOC_USP7_MATH_1	833	837	PF00917	0.698
DOC_USP7_MATH_1	848	852	PF00917	0.698
DOC_USP7_MATH_1	913	917	PF00917	0.678
DOC_USP7_MATH_1	974	978	PF00917	0.699
DOC_USP7_UBL2_3	507	511	PF12436	0.498
DOC_WW_Pin1_4	10	15	PF00397	0.640
DOC_WW_Pin1_4	111	116	PF00397	0.543
DOC_WW_Pin1_4	176	181	PF00397	0.637
DOC_WW_Pin1_4	20	25	PF00397	0.555
DOC_WW_Pin1_4	227	232	PF00397	0.671
DOC_WW_Pin1_4	240	245	PF00397	0.606
DOC_WW_Pin1_4	259	264	PF00397	0.514
DOC_WW_Pin1_4	3	8	PF00397	0.634
DOC_WW_Pin1_4	32	37	PF00397	0.587
DOC_WW_Pin1_4	537	542	PF00397	0.568
DOC_WW_Pin1_4	622	627	PF00397	0.689
DOC_WW_Pin1_4	640	645	PF00397	0.675
DOC_WW_Pin1_4	65	70	PF00397	0.743
DOC_WW_Pin1_4	675	680	PF00397	0.675
DOC_WW_Pin1_4	753	758	PF00397	0.731
DOC_WW_Pin1_4	763	768	PF00397	0.604
DOC_WW_Pin1_4	838	843	PF00397	0.710
DOC_WW_Pin1_4	909	914	PF00397	0.762
DOC_WW_Pin1_4	97	102	PF00397	0.640
DOC_WW_Pin1_4	970	975	PF00397	0.685
LIG_14-3-3_CanoR_1	1034	1040	PF00244	0.442
LIG_14-3-3_CanoR_1	153	159	PF00244	0.518
LIG_14-3-3_CanoR_1	27	37	PF00244	0.637
LIG_14-3-3_CanoR_1	364	370	PF00244	0.628
LIG_14-3-3_CanoR_1	381	386	PF00244	0.516
LIG_14-3-3_CanoR_1	587	592	PF00244	0.544
LIG_14-3-3_CanoR_1	64	69	PF00244	0.679
LIG_14-3-3_CanoR_1	682	686	PF00244	0.715
LIG_14-3-3_CanoR_1	759	764	PF00244	0.686
LIG_14-3-3_CanoR_1	94	101	PF00244	0.634
LIG_Actin_WH2_2	918	933	PF00022	0.526
LIG_EVH1_1	391	395	PF00568	0.608
LIG_FHA_1	159	165	PF00498	0.487
LIG_FHA_1	314	320	PF00498	0.544
LIG_FHA_1	421	427	PF00498	0.535
LIG_FHA_1	525	531	PF00498	0.392
LIG_FHA_1	586	592	PF00498	0.688
LIG_FHA_1	664	670	PF00498	0.658
LIG_FHA_1	730	736	PF00498	0.668
LIG_FHA_1	82	88	PF00498	0.771
LIG_FHA_1	839	845	PF00498	0.695
LIG_FHA_1	958	964	PF00498	0.583
LIG_FHA_1	985	991	PF00498	0.636
LIG_FHA_2	155	161	PF00498	0.521
LIG_FHA_2	177	183	PF00498	0.636
LIG_FHA_2	250	256	PF00498	0.770
LIG_FHA_2	394	400	PF00498	0.612
LIG_FHA_2	879	885	PF00498	0.586
LIG_FHA_2	891	897	PF00498	0.566
LIG_LIR_Apic_2	65	69	PF02991	0.677
LIG_LIR_Apic_2	723	729	PF02991	0.676
LIG_LIR_Apic_2	778	782	PF02991	0.596
LIG_LIR_Gen_1	1019	1030	PF02991	0.527
LIG_LIR_Gen_1	273	283	PF02991	0.505
LIG_LIR_Gen_1	333	343	PF02991	0.554
LIG_LIR_Gen_1	421	429	PF02991	0.500
LIG_LIR_Gen_1	678	688	PF02991	0.638
LIG_LIR_LC3C_4	689	694	PF02991	0.663
LIG_LIR_Nem_3	1019	1025	PF02991	0.529
LIG_LIR_Nem_3	273	279	PF02991	0.560
LIG_LIR_Nem_3	333	338	PF02991	0.546
LIG_LIR_Nem_3	421	427	PF02991	0.565
LIG_SH2_CRK	276	280	PF00017	0.519
LIG_SH2_CRK	424	428	PF00017	0.502
LIG_SH2_CRK	779	783	PF00017	0.596
LIG_SH2_NCK_1	1022	1026	PF00017	0.521
LIG_SH2_NCK_1	38	42	PF00017	0.564
LIG_SH2_NCK_1	385	389	PF00017	0.595
LIG_SH2_SRC	1022	1025	PF00017	0.519
LIG_SH2_STAP1	108	112	PF00017	0.563
LIG_SH2_STAP1	38	42	PF00017	0.636
LIG_SH2_STAP1	385	389	PF00017	0.595
LIG_SH2_STAT3	37	40	PF00017	0.544
LIG_SH2_STAT5	337	340	PF00017	0.557
LIG_SH2_STAT5	433	436	PF00017	0.385
LIG_SH2_STAT5	854	857	PF00017	0.611
LIG_SH3_2	376	381	PF14604	0.609
LIG_SH3_3	109	115	PF00018	0.642
LIG_SH3_3	218	224	PF00018	0.534
LIG_SH3_3	370	376	PF00018	0.657
LIG_SH3_3	389	395	PF00018	0.631
LIG_SH3_3	673	679	PF00018	0.760
LIG_SH3_3	852	858	PF00018	0.578
LIG_SUMO_SIM_anti_2	689	695	PF11976	0.665
LIG_SUMO_SIM_par_1	210	215	PF11976	0.557
LIG_SUMO_SIM_par_1	689	695	PF11976	0.665
LIG_TRAF2_1	1003	1006	PF00917	0.506
LIG_TRAF2_1	157	160	PF00917	0.545
LIG_TRAF2_1	455	458	PF00917	0.471
LIG_TRAF2_1	462	465	PF00917	0.487
LIG_TRAF2_1	631	634	PF00917	0.758
MOD_CDC14_SPxK_1	756	759	PF00782	0.671
MOD_CDK_SPK_2	3	8	PF00069	0.584
MOD_CDK_SPK_2	838	843	PF00069	0.679
MOD_CDK_SPK_2	97	102	PF00069	0.548
MOD_CDK_SPxK_1	10	16	PF00069	0.666
MOD_CDK_SPxK_1	640	646	PF00069	0.636
MOD_CDK_SPxK_1	753	759	PF00069	0.672
MOD_CDK_SPxxK_3	20	27	PF00069	0.584
MOD_CDK_SPxxK_3	65	72	PF00069	0.678
MOD_CDK_SPxxK_3	675	682	PF00069	0.648
MOD_CK1_1	111	117	PF00069	0.578
MOD_CK1_1	171	177	PF00069	0.639
MOD_CK1_1	227	233	PF00069	0.689
MOD_CK1_1	262	268	PF00069	0.629
MOD_CK1_1	28	34	PF00069	0.639
MOD_CK1_1	46	52	PF00069	0.501
MOD_CK1_1	54	60	PF00069	0.589
MOD_CK1_1	566	572	PF00069	0.578
MOD_CK1_1	590	596	PF00069	0.570
MOD_CK1_1	600	606	PF00069	0.553
MOD_CK1_1	649	655	PF00069	0.670
MOD_CK1_1	68	74	PF00069	0.565
MOD_CK1_1	695	701	PF00069	0.737
MOD_CK1_1	742	748	PF00069	0.696
MOD_CK1_1	772	778	PF00069	0.577
MOD_CK1_1	80	86	PF00069	0.602
MOD_CK1_1	825	831	PF00069	0.651
MOD_CK1_1	836	842	PF00069	0.611
MOD_CK1_1	905	911	PF00069	0.625
MOD_CK1_1	966	972	PF00069	0.651
MOD_CK1_1	97	103	PF00069	0.665
MOD_CK1_1	973	979	PF00069	0.632
MOD_CK2_1	154	160	PF00069	0.520
MOD_CK2_1	249	255	PF00069	0.642
MOD_CK2_1	451	457	PF00069	0.480
MOD_CK2_1	553	559	PF00069	0.800
MOD_CK2_1	791	797	PF00069	0.597
MOD_CK2_1	878	884	PF00069	0.683
MOD_CK2_1	890	896	PF00069	0.574
MOD_Cter_Amidation	614	617	PF01082	0.682
MOD_DYRK1A_RPxSP_1	838	842	PF00069	0.679
MOD_GlcNHglycan	131	134	PF01048	0.661
MOD_GlcNHglycan	170	173	PF01048	0.621
MOD_GlcNHglycan	204	207	PF01048	0.441
MOD_GlcNHglycan	226	229	PF01048	0.688
MOD_GlcNHglycan	27	30	PF01048	0.665
MOD_GlcNHglycan	290	293	PF01048	0.663
MOD_GlcNHglycan	3	6	PF01048	0.676
MOD_GlcNHglycan	340	343	PF01048	0.565
MOD_GlcNHglycan	43	46	PF01048	0.649
MOD_GlcNHglycan	452	456	PF01048	0.407
MOD_GlcNHglycan	485	488	PF01048	0.475
MOD_GlcNHglycan	555	558	PF01048	0.807
MOD_GlcNHglycan	56	59	PF01048	0.552
MOD_GlcNHglycan	561	564	PF01048	0.703
MOD_GlcNHglycan	599	602	PF01048	0.601
MOD_GlcNHglycan	606	609	PF01048	0.623
MOD_GlcNHglycan	612	615	PF01048	0.599
MOD_GlcNHglycan	633	638	PF01048	0.633
MOD_GlcNHglycan	640	643	PF01048	0.675
MOD_GlcNHglycan	655	658	PF01048	0.746
MOD_GlcNHglycan	694	697	PF01048	0.769
MOD_GlcNHglycan	729	732	PF01048	0.603
MOD_GlcNHglycan	79	82	PF01048	0.690
MOD_GlcNHglycan	825	828	PF01048	0.707
MOD_GlcNHglycan	838	841	PF01048	0.595
MOD_GlcNHglycan	851	854	PF01048	0.666
MOD_GlcNHglycan	881	884	PF01048	0.678
MOD_GlcNHglycan	91	94	PF01048	0.672
MOD_GlcNHglycan	915	918	PF01048	0.596
MOD_GlcNHglycan	968	971	PF01048	0.658
MOD_GSK3_1	154	161	PF00069	0.483
MOD_GSK3_1	171	178	PF00069	0.591
MOD_GSK3_1	223	230	PF00069	0.709
MOD_GSK3_1	236	243	PF00069	0.574
MOD_GSK3_1	258	265	PF00069	0.662
MOD_GSK3_1	28	35	PF00069	0.642
MOD_GSK3_1	3	10	PF00069	0.575
MOD_GSK3_1	393	400	PF00069	0.614
MOD_GSK3_1	41	48	PF00069	0.618
MOD_GSK3_1	49	56	PF00069	0.707
MOD_GSK3_1	559	566	PF00069	0.672
MOD_GSK3_1	583	590	PF00069	0.638
MOD_GSK3_1	600	607	PF00069	0.672
MOD_GSK3_1	633	640	PF00069	0.685
MOD_GSK3_1	64	71	PF00069	0.592
MOD_GSK3_1	646	653	PF00069	0.647
MOD_GSK3_1	692	699	PF00069	0.749
MOD_GSK3_1	739	746	PF00069	0.668
MOD_GSK3_1	759	766	PF00069	0.552
MOD_GSK3_1	768	775	PF00069	0.619
MOD_GSK3_1	77	84	PF00069	0.588
MOD_GSK3_1	905	912	PF00069	0.628
MOD_GSK3_1	966	973	PF00069	0.658
MOD_N-GLC_1	1	6	PF02516	0.669
MOD_N-GLC_1	129	134	PF02516	0.649
MOD_N-GLC_1	183	188	PF02516	0.648
MOD_N-GLC_1	408	413	PF02516	0.510
MOD_N-GLC_1	550	555	PF02516	0.651
MOD_N-GLC_1	696	701	PF02516	0.685
MOD_N-GLC_1	705	710	PF02516	0.645
MOD_N-GLC_1	878	883	PF02516	0.680
MOD_N-GLC_1	963	968	PF02516	0.604
MOD_N-GLC_2	577	579	PF02516	0.662
MOD_NEK2_1	1	6	PF00069	0.669
MOD_NEK2_1	123	128	PF00069	0.580
MOD_NEK2_1	154	159	PF00069	0.517
MOD_NEK2_1	25	30	PF00069	0.647
MOD_NEK2_1	283	288	PF00069	0.645
MOD_NEK2_1	338	343	PF00069	0.564
MOD_NEK2_1	50	55	PF00069	0.764
MOD_NEK2_1	506	511	PF00069	0.565
MOD_NEK2_1	567	572	PF00069	0.662
MOD_NEK2_1	599	604	PF00069	0.586
MOD_NEK2_1	638	643	PF00069	0.620
MOD_NEK2_1	650	655	PF00069	0.569
MOD_NEK2_1	660	665	PF00069	0.631
MOD_NEK2_1	692	697	PF00069	0.652
MOD_NEK2_1	751	756	PF00069	0.673
MOD_NEK2_1	877	882	PF00069	0.603
MOD_NEK2_1	890	895	PF00069	0.625
MOD_NEK2_2	108	113	PF00069	0.635
MOD_NEK2_2	244	249	PF00069	0.651
MOD_NEK2_2	362	367	PF00069	0.544
MOD_NEK2_2	833	838	PF00069	0.647
MOD_PIKK_1	118	124	PF00454	0.652
MOD_PIKK_1	467	473	PF00454	0.516
MOD_PIKK_1	663	669	PF00454	0.682
MOD_PIKK_1	811	817	PF00454	0.587
MOD_PK_1	587	593	PF00069	0.617
MOD_PKA_1	344	350	PF00069	0.501
MOD_PKA_2	249	255	PF00069	0.642
MOD_PKA_2	344	350	PF00069	0.634
MOD_PKA_2	663	669	PF00069	0.660
MOD_PKA_2	681	687	PF00069	0.617
MOD_PKA_2	804	810	PF00069	0.681
MOD_PKA_2	884	890	PF00069	0.684
MOD_PKA_2	957	963	PF00069	0.556
MOD_PKB_1	587	595	PF00069	0.547
MOD_Plk_1	283	289	PF00069	0.523
MOD_Plk_1	295	301	PF00069	0.584
MOD_Plk_1	408	414	PF00069	0.524
MOD_Plk_1	420	426	PF00069	0.440
MOD_Plk_1	451	457	PF00069	0.480
MOD_Plk_1	705	711	PF00069	0.616
MOD_Plk_1	963	969	PF00069	0.612
MOD_Plk_4	236	242	PF00069	0.654
MOD_Plk_4	262	268	PF00069	0.669
MOD_Plk_4	330	336	PF00069	0.536
MOD_Plk_4	408	414	PF00069	0.510
MOD_Plk_4	46	52	PF00069	0.721
MOD_Plk_4	539	545	PF00069	0.525
MOD_Plk_4	687	693	PF00069	0.765
MOD_ProDKin_1	10	16	PF00069	0.643
MOD_ProDKin_1	111	117	PF00069	0.542
MOD_ProDKin_1	176	182	PF00069	0.638
MOD_ProDKin_1	20	26	PF00069	0.555
MOD_ProDKin_1	227	233	PF00069	0.669
MOD_ProDKin_1	240	246	PF00069	0.604
MOD_ProDKin_1	259	265	PF00069	0.508
MOD_ProDKin_1	3	9	PF00069	0.634
MOD_ProDKin_1	32	38	PF00069	0.588
MOD_ProDKin_1	537	543	PF00069	0.578
MOD_ProDKin_1	622	628	PF00069	0.688
MOD_ProDKin_1	640	646	PF00069	0.677
MOD_ProDKin_1	65	71	PF00069	0.742
MOD_ProDKin_1	675	681	PF00069	0.676
MOD_ProDKin_1	753	759	PF00069	0.734
MOD_ProDKin_1	763	769	PF00069	0.604
MOD_ProDKin_1	838	844	PF00069	0.709
MOD_ProDKin_1	909	915	PF00069	0.761
MOD_ProDKin_1	97	103	PF00069	0.640
MOD_ProDKin_1	970	976	PF00069	0.686
MOD_SUMO_rev_2	470	480	PF00179	0.441
MOD_SUMO_rev_2	521	527	PF00179	0.518
MOD_SUMO_rev_2	737	742	PF00179	0.668
TRG_DiLeu_BaEn_1	327	332	PF01217	0.493
TRG_DiLeu_BaEn_1	378	383	PF01217	0.547
TRG_DiLeu_BaEn_1	634	639	PF01217	0.628
TRG_DiLeu_BaLyEn_6	315	320	PF01217	0.545
TRG_ENDOCYTIC_2	1022	1025	PF00928	0.519
TRG_ENDOCYTIC_2	276	279	PF00928	0.630
TRG_ENDOCYTIC_2	424	427	PF00928	0.500
TRG_ENDOCYTIC_2	499	502	PF00928	0.537
TRG_ER_diArg_1	152	154	PF00400	0.471
TRG_ER_diArg_1	274	276	PF00400	0.560
TRG_ER_diArg_1	747	750	PF00400	0.698
TRG_ER_diArg_1	919	922	PF00400	0.528
TRG_ER_diArg_1	951	954	PF00400	0.534
TRG_NES_CRM1_1	998	1013	PF08389	0.541
TRG_NLS_MonoExtN_4	343	348	PF00514	0.490
TRG_Pf-PMV_PEXEL_1	1002	1006	PF00026	0.510
TRG_Pf-PMV_PEXEL_1	318	322	PF00026	0.538
TRG_Pf-PMV_PEXEL_1	440	444	PF00026	0.485
TRG_Pf-PMV_PEXEL_1	528	533	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	759	764	PF00026	0.686

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WYH7	Leishmania donovani	87%	100%
A4HDH3	Leishmania braziliensis	62%	100%
A4I0V4	Leishmania infantum	87%	100%
E9AWV8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%