Crossover junction endonuclease MUS81

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ERCC4 domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4QAH9_LEIMA

TriTrypDb:

LmjF.24.1520 , LMJLV39_240022100 , LMJSD75_240021400

Length:

1152

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	3
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0048476	Holliday junction resolvase complex	5	2
GO:0110165	cellular anatomical entity	1	3
GO:0140535	intracellular protein-containing complex	2	2
GO:1902494	catalytic complex	2	2
GO:1905347	endodeoxyribonuclease complex	4	2
GO:1905348	endonuclease complex	3	2

Expansion

Sequence features

Q4QAH9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAH9

Function

Biological processes
Term	Name	Level	Count
GO:0000075	cell cycle checkpoint signaling	4	2
GO:0000077	DNA damage checkpoint signaling	5	2
GO:0000712	resolution of meiotic recombination intermediates	4	2
GO:0000724	double-strand break repair via homologous recombination	7	2
GO:0000725	recombinational repair	6	2
GO:0000727	double-strand break repair via break-induced replication	8	2
GO:0000737	obsolete DNA catabolic process, endonucleolytic	6	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006302	double-strand break repair	6	7
GO:0006308	DNA catabolic process	5	7
GO:0006310	DNA recombination	5	3
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0007093	mitotic cell cycle checkpoint signaling	4	2
GO:0007165	signal transduction	2	2
GO:0007346	regulation of mitotic cell cycle	5	2
GO:0008152	metabolic process	1	7
GO:0009056	catabolic process	2	7
GO:0009057	macromolecule catabolic process	4	7
GO:0009987	cellular process	1	7
GO:0010564	regulation of cell cycle process	5	2
GO:0010948	negative regulation of cell cycle process	6	2
GO:0019439	aromatic compound catabolic process	4	7
GO:0022402	cell cycle process	2	2
GO:0022414	reproductive process	1	2
GO:0031570	DNA integrity checkpoint signaling	5	2
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	7	2
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0034655	nucleobase-containing compound catabolic process	4	7
GO:0035556	intracellular signal transduction	3	2
GO:0042770	signal transduction in response to DNA damage	4	2
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044248	cellular catabolic process	3	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0044265	obsolete cellular macromolecule catabolic process	4	7
GO:0044270	cellular nitrogen compound catabolic process	4	7
GO:0044773	mitotic DNA damage checkpoint signaling	6	2
GO:0044774	mitotic DNA integrity checkpoint signaling	5	2
GO:0045786	negative regulation of cell cycle	5	2
GO:0045930	negative regulation of mitotic cell cycle	6	2
GO:0046483	heterocycle metabolic process	3	7
GO:0046700	heterocycle catabolic process	4	7
GO:0048519	negative regulation of biological process	3	2
GO:0048523	negative regulation of cellular process	4	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0050896	response to stimulus	1	7
GO:0051716	cellular response to stimulus	2	7
GO:0051726	regulation of cell cycle	4	2
GO:0061982	meiosis I cell cycle process	3	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:1901361	organic cyclic compound catabolic process	4	7
GO:1901575	organic substance catabolic process	3	7
GO:1901987	regulation of cell cycle phase transition	6	2
GO:1901988	negative regulation of cell cycle phase transition	7	2
GO:1903046	meiotic cell cycle process	2	2
GO:1903047	mitotic cell cycle process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0004518	nuclease activity	4	7
GO:0004519	endonuclease activity	5	7
GO:0004520	DNA endonuclease activity	5	7
GO:0004536	DNA nuclease activity	4	7
GO:0005488	binding	1	7
GO:0008821	crossover junction DNA endonuclease activity	7	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	6	7
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	6	7
GO:0048256	flap endonuclease activity	6	2
GO:0048257	3'-flap endonuclease activity	7	2
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	165	169	PF00656	0.577
CLV_C14_Caspase3-7	284	288	PF00656	0.781
CLV_C14_Caspase3-7	302	306	PF00656	0.518
CLV_C14_Caspase3-7	314	318	PF00656	0.635
CLV_NRD_NRD_1	1116	1118	PF00675	0.527
CLV_NRD_NRD_1	115	117	PF00675	0.584
CLV_NRD_NRD_1	229	231	PF00675	0.591
CLV_NRD_NRD_1	321	323	PF00675	0.660
CLV_NRD_NRD_1	778	780	PF00675	0.687
CLV_NRD_NRD_1	788	790	PF00675	0.262
CLV_NRD_NRD_1	857	859	PF00675	0.312
CLV_NRD_NRD_1	877	879	PF00675	0.388
CLV_NRD_NRD_1	992	994	PF00675	0.502
CLV_PCSK_FUR_1	113	117	PF00082	0.562
CLV_PCSK_FUR_1	989	993	PF00082	0.482
CLV_PCSK_KEX2_1	1115	1117	PF00082	0.530
CLV_PCSK_KEX2_1	115	117	PF00082	0.584
CLV_PCSK_KEX2_1	229	231	PF00082	0.591
CLV_PCSK_KEX2_1	323	325	PF00082	0.652
CLV_PCSK_KEX2_1	778	780	PF00082	0.683
CLV_PCSK_KEX2_1	877	879	PF00082	0.388
CLV_PCSK_KEX2_1	991	993	PF00082	0.487
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.652
CLV_PCSK_PC7_1	1112	1118	PF00082	0.505
CLV_PCSK_SKI1_1	1079	1083	PF00082	0.499
CLV_PCSK_SKI1_1	35	39	PF00082	0.634
CLV_PCSK_SKI1_1	463	467	PF00082	0.698
CLV_PCSK_SKI1_1	634	638	PF00082	0.634
CLV_PCSK_SKI1_1	877	881	PF00082	0.394
DEG_APCC_DBOX_1	60	68	PF00400	0.558
DEG_COP1_1	827	837	PF00400	0.243
DEG_SCF_FBW7_1	396	402	PF00400	0.711
DEG_SPOP_SBC_1	1045	1049	PF00917	0.432
DEG_SPOP_SBC_1	687	691	PF00917	0.661
DOC_ANK_TNKS_1	261	268	PF00023	0.673
DOC_ANK_TNKS_1	489	496	PF00023	0.607
DOC_ANK_TNKS_1	992	999	PF00023	0.577
DOC_CKS1_1	186	191	PF01111	0.659
DOC_CKS1_1	396	401	PF01111	0.707
DOC_CYCLIN_RxL_1	32	43	PF00134	0.636
DOC_CYCLIN_yCln2_LP_2	297	303	PF00134	0.661
DOC_CYCLIN_yCln2_LP_2	608	614	PF00134	0.626
DOC_MAPK_gen_1	1136	1142	PF00069	0.413
DOC_MAPK_gen_1	754	763	PF00069	0.481
DOC_MAPK_MEF2A_6	413	421	PF00069	0.521
DOC_PP1_RVXF_1	575	581	PF00149	0.361
DOC_PP1_RVXF_1	752	758	PF00149	0.502
DOC_PP1_RVXF_1	884	891	PF00149	0.388
DOC_PP2B_LxvP_1	250	253	PF13499	0.686
DOC_PP2B_LxvP_1	297	300	PF13499	0.684
DOC_PP2B_LxvP_1	608	611	PF13499	0.649
DOC_PP2B_LxvP_1	93	96	PF13499	0.569
DOC_PP4_FxxP_1	293	296	PF00568	0.621
DOC_USP7_MATH_1	1095	1099	PF00917	0.419
DOC_USP7_MATH_1	180	184	PF00917	0.691
DOC_USP7_MATH_1	205	209	PF00917	0.730
DOC_USP7_MATH_1	506	510	PF00917	0.521
DOC_USP7_MATH_1	625	629	PF00917	0.725
DOC_USP7_MATH_1	65	69	PF00917	0.694
DOC_USP7_MATH_1	686	690	PF00917	0.680
DOC_USP7_MATH_1	694	698	PF00917	0.584
DOC_USP7_MATH_1	794	798	PF00917	0.330
DOC_USP7_MATH_1	835	839	PF00917	0.312
DOC_USP7_MATH_1	898	902	PF00917	0.358
DOC_USP7_MATH_1	932	936	PF00917	0.474
DOC_USP7_MATH_1	948	952	PF00917	0.315
DOC_USP7_MATH_2	96	102	PF00917	0.651
DOC_WW_Pin1_4	117	122	PF00397	0.607
DOC_WW_Pin1_4	148	153	PF00397	0.597
DOC_WW_Pin1_4	156	161	PF00397	0.613
DOC_WW_Pin1_4	185	190	PF00397	0.709
DOC_WW_Pin1_4	196	201	PF00397	0.571
DOC_WW_Pin1_4	235	240	PF00397	0.763
DOC_WW_Pin1_4	268	273	PF00397	0.658
DOC_WW_Pin1_4	331	336	PF00397	0.752
DOC_WW_Pin1_4	361	366	PF00397	0.761
DOC_WW_Pin1_4	380	385	PF00397	0.537
DOC_WW_Pin1_4	392	397	PF00397	0.654
DOC_WW_Pin1_4	427	432	PF00397	0.569
DOC_WW_Pin1_4	628	633	PF00397	0.617
DOC_WW_Pin1_4	638	643	PF00397	0.630
DOC_WW_Pin1_4	688	693	PF00397	0.619
DOC_WW_Pin1_4	703	708	PF00397	0.622
DOC_WW_Pin1_4	718	723	PF00397	0.543
DOC_WW_Pin1_4	731	736	PF00397	0.486
DOC_WW_Pin1_4	88	93	PF00397	0.716
DOC_WW_Pin1_4	880	885	PF00397	0.312
DOC_WW_Pin1_4	926	931	PF00397	0.361
LIG_14-3-3_CanoR_1	1077	1086	PF00244	0.437
LIG_14-3-3_CanoR_1	1090	1099	PF00244	0.458
LIG_14-3-3_CanoR_1	113	122	PF00244	0.716
LIG_14-3-3_CanoR_1	1130	1139	PF00244	0.432
LIG_14-3-3_CanoR_1	125	130	PF00244	0.594
LIG_14-3-3_CanoR_1	326	335	PF00244	0.674
LIG_14-3-3_CanoR_1	503	512	PF00244	0.545
LIG_14-3-3_CanoR_1	557	565	PF00244	0.509
LIG_14-3-3_CanoR_1	663	673	PF00244	0.682
LIG_14-3-3_CanoR_1	720	729	PF00244	0.593
LIG_14-3-3_CanoR_1	858	864	PF00244	0.319
LIG_14-3-3_CanoR_1	872	880	PF00244	0.424
LIG_14-3-3_CanoR_1	963	973	PF00244	0.505
LIG_14-3-3_CanoR_1	983	989	PF00244	0.462
LIG_BIR_II_1	1	5	PF00653	0.679
LIG_BIR_III_1	1	5	PF00653	0.631
LIG_BIR_III_2	1123	1127	PF00653	0.440
LIG_BIR_III_3	1	5	PF00653	0.631
LIG_BIR_III_4	168	172	PF00653	0.567
LIG_BRCT_BRCA1_1	289	293	PF00533	0.669
LIG_BRCT_BRCA1_1	429	433	PF00533	0.577
LIG_BRCT_BRCA1_1	969	973	PF00533	0.312
LIG_BRCT_BRCA1_2	969	975	PF00533	0.307
LIG_deltaCOP1_diTrp_1	305	311	PF00928	0.620
LIG_FHA_1	1141	1147	PF00498	0.423
LIG_FHA_1	139	145	PF00498	0.630
LIG_FHA_1	15	21	PF00498	0.561
LIG_FHA_1	173	179	PF00498	0.672
LIG_FHA_1	400	406	PF00498	0.678
LIG_FHA_1	49	55	PF00498	0.593
LIG_FHA_1	496	502	PF00498	0.607
LIG_FHA_1	505	511	PF00498	0.586
LIG_FHA_1	665	671	PF00498	0.648
LIG_FHA_1	706	712	PF00498	0.527
LIG_FHA_1	750	756	PF00498	0.466
LIG_FHA_1	966	972	PF00498	0.388
LIG_FHA_2	163	169	PF00498	0.705
LIG_FHA_2	300	306	PF00498	0.658
LIG_FHA_2	312	318	PF00498	0.565
LIG_FHA_2	334	340	PF00498	0.673
LIG_FHA_2	396	402	PF00498	0.711
LIG_FHA_2	449	455	PF00498	0.669
LIG_FHA_2	550	556	PF00498	0.432
LIG_FHA_2	617	623	PF00498	0.653
LIG_FHA_2	69	75	PF00498	0.573
LIG_FHA_2	726	732	PF00498	0.613
LIG_FHA_2	826	832	PF00498	0.315
LIG_FHA_2	858	864	PF00498	0.312
LIG_FHA_2	917	923	PF00498	0.340
LIG_LIR_Apic_2	290	296	PF02991	0.620
LIG_LIR_Gen_1	341	348	PF02991	0.643
LIG_LIR_Gen_1	970	981	PF02991	0.388
LIG_LIR_LC3C_4	853	856	PF02991	0.312
LIG_LIR_Nem_3	1101	1107	PF02991	0.372
LIG_LIR_Nem_3	341	346	PF02991	0.744
LIG_LIR_Nem_3	883	888	PF02991	0.350
LIG_LIR_Nem_3	970	976	PF02991	0.388
LIG_NRBOX	1095	1101	PF00104	0.380
LIG_NRBOX	415	421	PF00104	0.592
LIG_PDZ_Class_3	1147	1152	PF00595	0.506
LIG_Pex14_1	307	311	PF04695	0.623
LIG_Pex14_1	759	763	PF04695	0.391
LIG_PTB_Apo_2	49	56	PF02174	0.505
LIG_SH2_CRK	1104	1108	PF00017	0.424
LIG_SH2_CRK	639	643	PF00017	0.629
LIG_SH2_NCK_1	582	586	PF00017	0.578
LIG_SH2_PTP2	1139	1142	PF00017	0.484
LIG_SH2_STAT3	873	876	PF00017	0.312
LIG_SH2_STAT5	1139	1142	PF00017	0.484
LIG_SH2_STAT5	873	876	PF00017	0.291
LIG_SH3_2	237	242	PF14604	0.636
LIG_SH3_3	151	157	PF00018	0.703
LIG_SH3_3	184	190	PF00018	0.730
LIG_SH3_3	231	237	PF00018	0.670
LIG_SH3_3	280	286	PF00018	0.658
LIG_SH3_3	393	399	PF00018	0.633
LIG_SH3_3	400	406	PF00018	0.607
LIG_SH3_3	519	525	PF00018	0.611
LIG_SH3_3	590	596	PF00018	0.593
LIG_SH3_3	608	614	PF00018	0.649
LIG_SH3_3	656	662	PF00018	0.580
LIG_SH3_3	667	673	PF00018	0.810
LIG_SH3_3	674	680	PF00018	0.652
LIG_SH3_3	701	707	PF00018	0.689
LIG_SH3_3	829	835	PF00018	0.243
LIG_SH3_3	89	95	PF00018	0.768
LIG_SUMO_SIM_anti_2	414	421	PF11976	0.607
LIG_SUMO_SIM_par_1	804	810	PF11976	0.312
LIG_TRAF2_1	743	746	PF00917	0.543
LIG_TRAF2_1	812	815	PF00917	0.315
LIG_UBA3_1	1056	1063	PF00899	0.338
LIG_WW_3	631	635	PF00397	0.621
MOD_CDC14_SPxK_1	199	202	PF00782	0.569
MOD_CDC14_SPxK_1	631	634	PF00782	0.620
MOD_CDC14_SPxK_1	883	886	PF00782	0.388
MOD_CDK_SPK_2	392	397	PF00069	0.561
MOD_CDK_SPxK_1	196	202	PF00069	0.575
MOD_CDK_SPxK_1	628	634	PF00069	0.620
MOD_CDK_SPxK_1	880	886	PF00069	0.388
MOD_CDK_SPxxK_3	235	242	PF00069	0.639
MOD_CK1_1	1046	1052	PF00069	0.423
MOD_CK1_1	1098	1104	PF00069	0.414
MOD_CK1_1	117	123	PF00069	0.693
MOD_CK1_1	138	144	PF00069	0.635
MOD_CK1_1	238	244	PF00069	0.725
MOD_CK1_1	273	279	PF00069	0.715
MOD_CK1_1	334	340	PF00069	0.737
MOD_CK1_1	361	367	PF00069	0.684
MOD_CK1_1	383	389	PF00069	0.657
MOD_CK1_1	395	401	PF00069	0.583
MOD_CK1_1	42	48	PF00069	0.585
MOD_CK1_1	477	483	PF00069	0.601
MOD_CK1_1	567	573	PF00069	0.604
MOD_CK1_1	588	594	PF00069	0.518
MOD_CK1_1	626	632	PF00069	0.611
MOD_CK1_1	645	651	PF00069	0.548
MOD_CK1_1	68	74	PF00069	0.668
MOD_CK1_1	716	722	PF00069	0.579
MOD_CK1_1	734	740	PF00069	0.689
MOD_CK1_1	88	94	PF00069	0.549
MOD_CK1_1	903	909	PF00069	0.296
MOD_CK1_1	97	103	PF00069	0.673
MOD_CK2_1	333	339	PF00069	0.688
MOD_CK2_1	395	401	PF00069	0.706
MOD_CK2_1	448	454	PF00069	0.705
MOD_CK2_1	549	555	PF00069	0.416
MOD_CK2_1	616	622	PF00069	0.620
MOD_CK2_1	809	815	PF00069	0.321
MOD_CK2_1	933	939	PF00069	0.315
MOD_Cter_Amidation	776	779	PF01082	0.653
MOD_DYRK1A_RPxSP_1	928	932	PF00069	0.388
MOD_GlcNHglycan	1018	1022	PF01048	0.606
MOD_GlcNHglycan	1069	1072	PF01048	0.399
MOD_GlcNHglycan	107	110	PF01048	0.535
MOD_GlcNHglycan	1092	1095	PF01048	0.484
MOD_GlcNHglycan	141	144	PF01048	0.584
MOD_GlcNHglycan	182	185	PF01048	0.663
MOD_GlcNHglycan	220	223	PF01048	0.570
MOD_GlcNHglycan	23	26	PF01048	0.613
MOD_GlcNHglycan	273	276	PF01048	0.717
MOD_GlcNHglycan	283	286	PF01048	0.596
MOD_GlcNHglycan	328	331	PF01048	0.822
MOD_GlcNHglycan	336	339	PF01048	0.672
MOD_GlcNHglycan	355	358	PF01048	0.517
MOD_GlcNHglycan	471	474	PF01048	0.744
MOD_GlcNHglycan	486	489	PF01048	0.511
MOD_GlcNHglycan	527	530	PF01048	0.721
MOD_GlcNHglycan	583	586	PF01048	0.591
MOD_GlcNHglycan	590	593	PF01048	0.668
MOD_GlcNHglycan	604	607	PF01048	0.528
MOD_GlcNHglycan	652	655	PF01048	0.655
MOD_GlcNHglycan	67	70	PF01048	0.693
MOD_GlcNHglycan	670	673	PF01048	0.572
MOD_GlcNHglycan	696	699	PF01048	0.789
MOD_GlcNHglycan	736	739	PF01048	0.453
MOD_GlcNHglycan	767	770	PF01048	0.612
MOD_GlcNHglycan	775	778	PF01048	0.565
MOD_GlcNHglycan	835	838	PF01048	0.486
MOD_GlcNHglycan	87	90	PF01048	0.544
MOD_GlcNHglycan	900	903	PF01048	0.333
MOD_GlcNHglycan	939	942	PF01048	0.402
MOD_GlcNHglycan	946	949	PF01048	0.316
MOD_GlcNHglycan	999	1002	PF01048	0.560
MOD_GSK3_1	1057	1064	PF00069	0.500
MOD_GSK3_1	1095	1102	PF00069	0.462
MOD_GSK3_1	135	142	PF00069	0.580
MOD_GSK3_1	21	28	PF00069	0.659
MOD_GSK3_1	214	221	PF00069	0.558
MOD_GSK3_1	324	331	PF00069	0.815
MOD_GSK3_1	334	341	PF00069	0.792
MOD_GSK3_1	361	368	PF00069	0.649
MOD_GSK3_1	395	402	PF00069	0.783
MOD_GSK3_1	469	476	PF00069	0.758
MOD_GSK3_1	479	486	PF00069	0.562
MOD_GSK3_1	506	513	PF00069	0.602
MOD_GSK3_1	565	572	PF00069	0.417
MOD_GSK3_1	581	588	PF00069	0.527
MOD_GSK3_1	628	635	PF00069	0.611
MOD_GSK3_1	638	645	PF00069	0.658
MOD_GSK3_1	664	671	PF00069	0.814
MOD_GSK3_1	721	728	PF00069	0.560
MOD_GSK3_1	805	812	PF00069	0.388
MOD_GSK3_1	846	853	PF00069	0.322
MOD_GSK3_1	916	923	PF00069	0.497
MOD_GSK3_1	924	931	PF00069	0.313
MOD_GSK3_1	933	940	PF00069	0.231
MOD_GSK3_1	94	101	PF00069	0.707
MOD_GSK3_1	944	951	PF00069	0.454
MOD_GSK3_1	961	968	PF00069	0.315
MOD_LATS_1	1075	1081	PF00433	0.451
MOD_N-GLC_1	281	286	PF02516	0.562
MOD_N-GLC_1	425	430	PF02516	0.676
MOD_N-GLC_1	469	474	PF02516	0.550
MOD_N-GLC_1	602	607	PF02516	0.615
MOD_N-GLC_1	965	970	PF02516	0.340
MOD_NEK2_1	1038	1043	PF00069	0.627
MOD_NEK2_1	1057	1062	PF00069	0.370
MOD_NEK2_1	1099	1104	PF00069	0.469
MOD_NEK2_1	311	316	PF00069	0.642
MOD_NEK2_1	39	44	PF00069	0.683
MOD_NEK2_1	445	450	PF00069	0.684
MOD_NEK2_1	474	479	PF00069	0.595
MOD_NEK2_1	484	489	PF00069	0.722
MOD_NEK2_1	496	501	PF00069	0.611
MOD_NEK2_1	50	55	PF00069	0.578
MOD_NEK2_1	510	515	PF00069	0.561
MOD_NEK2_1	549	554	PF00069	0.552
MOD_NEK2_1	556	561	PF00069	0.438
MOD_NEK2_1	565	570	PF00069	0.542
MOD_NEK2_1	597	602	PF00069	0.731
MOD_NEK2_1	864	869	PF00069	0.312
MOD_NEK2_1	976	981	PF00069	0.456
MOD_NEK2_2	374	379	PF00069	0.584
MOD_PIKK_1	42	48	PF00454	0.614
MOD_PIKK_1	585	591	PF00454	0.493
MOD_PIKK_1	640	646	PF00454	0.669
MOD_PIKK_1	705	711	PF00454	0.548
MOD_PIKK_1	920	926	PF00454	0.340
MOD_PKA_1	115	121	PF00069	0.576
MOD_PKA_2	1038	1044	PF00069	0.486
MOD_PKA_2	1129	1135	PF00069	0.430
MOD_PKA_2	114	120	PF00069	0.669
MOD_PKA_2	214	220	PF00069	0.545
MOD_PKA_2	556	562	PF00069	0.457
MOD_PKA_2	626	632	PF00069	0.592
MOD_PKA_2	765	771	PF00069	0.612
MOD_PKA_2	857	863	PF00069	0.312
MOD_PKA_2	871	877	PF00069	0.353
MOD_PKA_2	964	970	PF00069	0.324
MOD_PKB_1	113	121	PF00069	0.627
MOD_PKB_1	218	226	PF00069	0.647
MOD_PKB_1	322	330	PF00069	0.652
MOD_PKB_1	942	950	PF00069	0.388
MOD_PKB_1	963	971	PF00069	0.388
MOD_Plk_1	864	870	PF00069	0.312
MOD_Plk_2-3	454	460	PF00069	0.664
MOD_Plk_4	1095	1101	PF00069	0.438
MOD_Plk_4	1103	1109	PF00069	0.415
MOD_Plk_4	386	392	PF00069	0.632
MOD_Plk_4	50	56	PF00069	0.587
MOD_Plk_4	645	651	PF00069	0.613
MOD_Plk_4	794	800	PF00069	0.322
MOD_Plk_4	850	856	PF00069	0.312
MOD_ProDKin_1	117	123	PF00069	0.607
MOD_ProDKin_1	148	154	PF00069	0.597
MOD_ProDKin_1	156	162	PF00069	0.618
MOD_ProDKin_1	185	191	PF00069	0.705
MOD_ProDKin_1	196	202	PF00069	0.569
MOD_ProDKin_1	235	241	PF00069	0.764
MOD_ProDKin_1	268	274	PF00069	0.661
MOD_ProDKin_1	331	337	PF00069	0.750
MOD_ProDKin_1	361	367	PF00069	0.759
MOD_ProDKin_1	380	386	PF00069	0.535
MOD_ProDKin_1	392	398	PF00069	0.654
MOD_ProDKin_1	427	433	PF00069	0.572
MOD_ProDKin_1	628	634	PF00069	0.620
MOD_ProDKin_1	638	644	PF00069	0.628
MOD_ProDKin_1	688	694	PF00069	0.619
MOD_ProDKin_1	703	709	PF00069	0.619
MOD_ProDKin_1	718	724	PF00069	0.549
MOD_ProDKin_1	731	737	PF00069	0.478
MOD_ProDKin_1	88	94	PF00069	0.717
MOD_ProDKin_1	880	886	PF00069	0.312
MOD_ProDKin_1	926	932	PF00069	0.361
MOD_SUMO_rev_2	853	861	PF00179	0.312
TRG_DiLeu_BaEn_1	412	417	PF01217	0.592
TRG_DiLeu_BaEn_1	875	880	PF01217	0.312
TRG_DiLeu_BaEn_2	968	974	PF01217	0.312
TRG_DiLeu_BaLyEn_6	157	162	PF01217	0.666
TRG_DiLeu_LyEn_5	875	880	PF01217	0.312
TRG_ENDOCYTIC_2	1104	1107	PF00928	0.414
TRG_ENDOCYTIC_2	1139	1142	PF00928	0.560
TRG_ER_diArg_1	1114	1117	PF00400	0.513
TRG_ER_diArg_1	112	115	PF00400	0.655
TRG_ER_diArg_1	229	232	PF00400	0.715
TRG_ER_diArg_1	577	580	PF00400	0.459
TRG_ER_diArg_1	700	703	PF00400	0.566
TRG_ER_diArg_1	754	757	PF00400	0.616
TRG_ER_diArg_1	877	879	PF00400	0.460
TRG_ER_diArg_1	942	945	PF00400	0.388
TRG_ER_diArg_1	962	965	PF00400	0.183
TRG_ER_diArg_1	988	991	PF00400	0.443
TRG_NLS_MonoExtC_3	321	326	PF00514	0.649
TRG_NLS_MonoExtN_4	320	327	PF00514	0.649

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEQ9	Leptomonas seymouri	39%	100%
A0A3Q8IEY2	Leishmania donovani	87%	100%
A4HDI9	Leishmania braziliensis	65%	100%
A4I0Z0	Leishmania infantum	87%	100%
E9AWZ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%