LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
Q4QAH1_LEIMA
TriTrypDb:
Length:
63

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QAH1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAH1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 16 18 PF00675 0.745
CLV_NRD_NRD_1 51 53 PF00675 0.584
CLV_PCSK_KEX2_1 16 18 PF00082 0.745
CLV_PCSK_KEX2_1 51 53 PF00082 0.580
DOC_WW_Pin1_4 22 27 PF00397 0.691
LIG_BIR_II_1 1 5 PF00653 0.751
LIG_FHA_2 56 62 PF00498 0.624
LIG_SH2_STAT5 57 60 PF00017 0.767
LIG_TRAF2_1 26 29 PF00917 0.643
MOD_CK1_1 34 40 PF00069 0.803
MOD_CK2_1 22 28 PF00069 0.606
MOD_CK2_1 7 13 PF00069 0.611
MOD_GlcNHglycan 33 36 PF01048 0.738
MOD_GlcNHglycan 9 12 PF01048 0.674
MOD_GSK3_1 27 34 PF00069 0.606
MOD_N-GLC_1 7 12 PF02516 0.677
MOD_NEK2_1 1 6 PF00069 0.683
MOD_PIKK_1 1 7 PF00454 0.745
MOD_PIKK_1 34 40 PF00454 0.689
MOD_Plk_2-3 24 30 PF00069 0.639
MOD_ProDKin_1 22 28 PF00069 0.694
TRG_ER_diArg_1 15 17 PF00400 0.744
TRG_ER_diArg_1 50 52 PF00400 0.584

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WYK1 Leishmania donovani 94% 98%
A4HDM0 Leishmania braziliensis 74% 95%
E9AH67 Leishmania infantum 94% 98%
E9AX05 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS