Phosphatidylinositol 3-kinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphatidylinositol 3-kinase, putative

Species:

Leishmania major

UniProt:

Q4QAC9_LEIMA

TriTrypDb:

LmjF.24.2010 , LMJLV39_240027800 , LMJSD75_240027100

Length:

1089

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0000407	phagophore assembly site	2	2
GO:0005737	cytoplasm	2	2
GO:0005768	endosome	7	2
GO:0005777	peroxisome	6	2
GO:0005942	phosphatidylinositol 3-kinase complex	3	2
GO:0016020	membrane	2	2
GO:0031410	cytoplasmic vesicle	6	2
GO:0031982	vesicle	4	2
GO:0032991	protein-containing complex	1	2
GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	5	2
GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	5	2
GO:0035032	phosphatidylinositol 3-kinase complex, class III	4	2
GO:0042579	microbody	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	2
GO:0097708	intracellular vesicle	5	2
GO:0098796	membrane protein complex	2	2
GO:0110165	cellular anatomical entity	1	2
GO:1902494	catalytic complex	2	2
GO:1990234	transferase complex	3	2

Expansion

Sequence features

Q4QAC9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAC9

Function

Biological processes
Term	Name	Level	Count
GO:0000045	autophagosome assembly	6	2
GO:0006629	lipid metabolic process	3	3
GO:0006644	phospholipid metabolic process	4	3
GO:0006650	glycerophospholipid metabolic process	5	3
GO:0006661	phosphatidylinositol biosynthetic process	6	3
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006810	transport	3	2
GO:0006897	endocytosis	5	2
GO:0006914	autophagy	3	2
GO:0006996	organelle organization	4	2
GO:0007033	vacuole organization	5	2
GO:0007165	signal transduction	2	7
GO:0008152	metabolic process	1	7
GO:0008610	lipid biosynthetic process	4	3
GO:0008654	phospholipid biosynthetic process	5	3
GO:0009056	catabolic process	2	2
GO:0009058	biosynthetic process	2	3
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	2
GO:0016192	vesicle-mediated transport	4	2
GO:0016310	phosphorylation	5	7
GO:0019637	organophosphate metabolic process	3	3
GO:0022607	cellular component assembly	4	2
GO:0030242	autophagy of peroxisome	4	2
GO:0035556	intracellular signal transduction	3	7
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	8	2
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	3
GO:0044248	cellular catabolic process	3	2
GO:0044249	cellular biosynthetic process	3	3
GO:0044255	cellular lipid metabolic process	3	3
GO:0045017	glycerolipid biosynthetic process	4	3
GO:0046474	glycerophospholipid biosynthetic process	5	3
GO:0046486	glycerolipid metabolic process	4	3
GO:0046488	phosphatidylinositol metabolic process	6	3
GO:0046854	phosphatidylinositol phosphate biosynthetic process	7	3
GO:0048015	phosphatidylinositol-mediated signaling	5	7
GO:0048017	inositol lipid-mediated signaling	4	7
GO:0050789	regulation of biological process	2	7
GO:0050794	regulation of cellular process	3	7
GO:0051179	localization	1	2
GO:0051234	establishment of localization	2	2
GO:0061919	process utilizing autophagic mechanism	2	2
GO:0065007	biological regulation	1	7
GO:0070925	organelle assembly	5	2
GO:0071704	organic substance metabolic process	2	3
GO:0071840	cellular component organization or biogenesis	2	2
GO:0090407	organophosphate biosynthetic process	4	3
GO:1901576	organic substance biosynthetic process	3	3
GO:1905037	autophagosome organization	6	2

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0016301	kinase activity	4	7
GO:0016303	1-phosphatidylinositol-3-kinase activity	6	6
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	6
GO:0035004	phosphatidylinositol 3-kinase activity	5	6
GO:0052742	phosphatidylinositol kinase activity	5	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.552
CLV_C14_Caspase3-7	650	654	PF00656	0.680
CLV_C14_Caspase3-7	666	670	PF00656	0.636
CLV_NRD_NRD_1	1007	1009	PF00675	0.304
CLV_NRD_NRD_1	243	245	PF00675	0.618
CLV_NRD_NRD_1	354	356	PF00675	0.525
CLV_NRD_NRD_1	418	420	PF00675	0.304
CLV_NRD_NRD_1	459	461	PF00675	0.366
CLV_NRD_NRD_1	542	544	PF00675	0.447
CLV_NRD_NRD_1	615	617	PF00675	0.683
CLV_NRD_NRD_1	677	679	PF00675	0.601
CLV_PCSK_KEX2_1	354	356	PF00082	0.525
CLV_PCSK_KEX2_1	418	420	PF00082	0.304
CLV_PCSK_KEX2_1	459	461	PF00082	0.325
CLV_PCSK_KEX2_1	542	544	PF00082	0.447
CLV_PCSK_KEX2_1	557	559	PF00082	0.308
CLV_PCSK_KEX2_1	615	617	PF00082	0.683
CLV_PCSK_KEX2_1	677	679	PF00082	0.601
CLV_PCSK_PC1ET2_1	557	559	PF00082	0.326
CLV_PCSK_SKI1_1	287	291	PF00082	0.551
CLV_PCSK_SKI1_1	399	403	PF00082	0.304
CLV_PCSK_SKI1_1	430	434	PF00082	0.369
CLV_PCSK_SKI1_1	538	542	PF00082	0.387
CLV_PCSK_SKI1_1	586	590	PF00082	0.420
CLV_PCSK_SKI1_1	602	606	PF00082	0.395
CLV_PCSK_SKI1_1	745	749	PF00082	0.416
CLV_PCSK_SKI1_1	900	904	PF00082	0.304
CLV_Separin_Metazoa	914	918	PF03568	0.304
DEG_APCC_DBOX_1	1037	1045	PF00400	0.411
DEG_APCC_DBOX_1	345	353	PF00400	0.440
DEG_APCC_DBOX_1	44	52	PF00400	0.434
DEG_APCC_DBOX_1	899	907	PF00400	0.304
DEG_MDM2_SWIB_1	1073	1080	PF02201	0.468
DOC_ANK_TNKS_1	458	465	PF00023	0.325
DOC_CDC14_PxL_1	217	225	PF14671	0.539
DOC_CKS1_1	783	788	PF01111	0.651
DOC_CKS1_1	870	875	PF01111	0.433
DOC_CYCLIN_RxL_1	535	545	PF00134	0.329
DOC_CYCLIN_RxL_1	563	573	PF00134	0.447
DOC_CYCLIN_yClb1_LxF_4	750	755	PF00134	0.337
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.473
DOC_MAPK_gen_1	1008	1015	PF00069	0.304
DOC_MAPK_gen_1	354	360	PF00069	0.517
DOC_MAPK_gen_1	396	404	PF00069	0.304
DOC_MAPK_gen_1	45	53	PF00069	0.432
DOC_MAPK_gen_1	707	716	PF00069	0.606
DOC_MAPK_gen_1	745	755	PF00069	0.431
DOC_MAPK_gen_1	976	984	PF00069	0.307
DOC_MAPK_MEF2A_6	1008	1017	PF00069	0.304
DOC_MAPK_MEF2A_6	1043	1052	PF00069	0.396
DOC_MAPK_MEF2A_6	748	755	PF00069	0.410
DOC_MAPK_MEF2A_6	846	854	PF00069	0.343
DOC_PP1_RVXF_1	383	389	PF00149	0.304
DOC_PP1_RVXF_1	404	411	PF00149	0.304
DOC_PP1_RVXF_1	675	682	PF00149	0.605
DOC_PP1_RVXF_1	750	756	PF00149	0.342
DOC_PP2B_LxvP_1	264	267	PF13499	0.455
DOC_PP4_FxxP_1	274	277	PF00568	0.558
DOC_PP4_FxxP_1	971	974	PF00568	0.304
DOC_USP7_MATH_1	280	284	PF00917	0.730
DOC_USP7_MATH_1	325	329	PF00917	0.480
DOC_USP7_MATH_1	628	632	PF00917	0.584
DOC_USP7_MATH_1	697	701	PF00917	0.639
DOC_USP7_MATH_1	791	795	PF00917	0.714
DOC_USP7_UBL2_3	1043	1047	PF12436	0.398
DOC_USP7_UBL2_3	592	596	PF12436	0.410
DOC_WW_Pin1_4	111	116	PF00397	0.417
DOC_WW_Pin1_4	56	61	PF00397	0.510
DOC_WW_Pin1_4	682	687	PF00397	0.718
DOC_WW_Pin1_4	693	698	PF00397	0.772
DOC_WW_Pin1_4	775	780	PF00397	0.808
DOC_WW_Pin1_4	782	787	PF00397	0.608
DOC_WW_Pin1_4	869	874	PF00397	0.357
DOC_WW_Pin1_4	91	96	PF00397	0.441
LIG_14-3-3_CanoR_1	244	254	PF00244	0.561
LIG_14-3-3_CanoR_1	281	289	PF00244	0.586
LIG_14-3-3_CanoR_1	47	52	PF00244	0.365
LIG_14-3-3_CanoR_1	54	58	PF00244	0.399
LIG_14-3-3_CanoR_1	547	555	PF00244	0.380
LIG_14-3-3_CanoR_1	583	593	PF00244	0.399
LIG_14-3-3_CanoR_1	602	612	PF00244	0.501
LIG_14-3-3_CanoR_1	719	729	PF00244	0.458
LIG_14-3-3_CanoR_1	752	760	PF00244	0.379
LIG_14-3-3_CanoR_1	922	928	PF00244	0.288
LIG_Actin_WH2_2	39	56	PF00022	0.425
LIG_Actin_WH2_2	746	761	PF00022	0.408
LIG_BIR_III_4	653	657	PF00653	0.693
LIG_BRCT_BRCA1_1	440	444	PF00533	0.304
LIG_BRCT_BRCA1_1	989	993	PF00533	0.304
LIG_Clathr_ClatBox_1	507	511	PF01394	0.369
LIG_Clathr_ClatBox_1	86	90	PF01394	0.493
LIG_Clathr_ClatBox_1	955	959	PF01394	0.304
LIG_CSL_BTD_1	783	786	PF09270	0.514
LIG_deltaCOP1_diTrp_1	134	139	PF00928	0.396
LIG_deltaCOP1_diTrp_1	20	31	PF00928	0.598
LIG_EH1_1	565	573	PF00400	0.441
LIG_FHA_1	1056	1062	PF00498	0.410
LIG_FHA_1	223	229	PF00498	0.534
LIG_FHA_1	257	263	PF00498	0.425
LIG_FHA_1	268	274	PF00498	0.474
LIG_FHA_1	362	368	PF00498	0.544
LIG_FHA_1	382	388	PF00498	0.304
LIG_FHA_1	63	69	PF00498	0.575
LIG_FHA_1	732	738	PF00498	0.469
LIG_FHA_1	81	87	PF00498	0.343
LIG_FHA_1	830	836	PF00498	0.433
LIG_FHA_1	910	916	PF00498	0.307
LIG_FHA_1	932	938	PF00498	0.320
LIG_FHA_2	120	126	PF00498	0.561
LIG_FHA_2	129	135	PF00498	0.387
LIG_FHA_2	31	37	PF00498	0.531
LIG_LIR_Apic_2	271	277	PF02991	0.531
LIG_LIR_Apic_2	397	403	PF02991	0.304
LIG_LIR_Gen_1	1002	1012	PF02991	0.304
LIG_LIR_Gen_1	1071	1080	PF02991	0.504
LIG_LIR_Gen_1	134	143	PF02991	0.410
LIG_LIR_Gen_1	309	319	PF02991	0.507
LIG_LIR_Gen_1	441	450	PF02991	0.304
LIG_LIR_Gen_1	754	763	PF02991	0.528
LIG_LIR_Gen_1	990	999	PF02991	0.304
LIG_LIR_Nem_3	1002	1007	PF02991	0.304
LIG_LIR_Nem_3	1071	1076	PF02991	0.450
LIG_LIR_Nem_3	134	139	PF02991	0.392
LIG_LIR_Nem_3	165	171	PF02991	0.357
LIG_LIR_Nem_3	21	27	PF02991	0.590
LIG_LIR_Nem_3	309	314	PF02991	0.496
LIG_LIR_Nem_3	441	447	PF02991	0.304
LIG_LIR_Nem_3	534	540	PF02991	0.368
LIG_LIR_Nem_3	754	758	PF02991	0.383
LIG_LIR_Nem_3	872	877	PF02991	0.364
LIG_LIR_Nem_3	893	898	PF02991	0.429
LIG_LIR_Nem_3	924	930	PF02991	0.321
LIG_LIR_Nem_3	959	963	PF02991	0.304
LIG_LIR_Nem_3	990	996	PF02991	0.304
LIG_MLH1_MIPbox_1	440	444	PF16413	0.304
LIG_MYND_1	682	686	PF01753	0.616
LIG_NRBOX	1014	1020	PF00104	0.304
LIG_NRBOX	348	354	PF00104	0.443
LIG_NRBOX	503	509	PF00104	0.325
LIG_PCNA_PIPBox_1	258	267	PF02747	0.338
LIG_PCNA_PIPBox_1	899	908	PF02747	0.304
LIG_PCNA_yPIPBox_3	252	265	PF02747	0.406
LIG_PCNA_yPIPBox_3	557	569	PF02747	0.448
LIG_PCNA_yPIPBox_3	899	907	PF02747	0.304
LIG_PCNA_yPIPBox_3	976	985	PF02747	0.304
LIG_Pex14_2	1073	1077	PF04695	0.458
LIG_Pex14_2	132	136	PF04695	0.416
LIG_REV1ctd_RIR_1	311	319	PF16727	0.509
LIG_SH2_CRK	1004	1008	PF00017	0.304
LIG_SH2_CRK	27	31	PF00017	0.602
LIG_SH2_CRK	874	878	PF00017	0.355
LIG_SH2_CRK	930	934	PF00017	0.304
LIG_SH2_NCK_1	103	107	PF00017	0.501
LIG_SH2_NCK_1	171	175	PF00017	0.507
LIG_SH2_NCK_1	37	41	PF00017	0.506
LIG_SH2_NCK_1	479	483	PF00017	0.369
LIG_SH2_SRC	265	268	PF00017	0.474
LIG_SH2_STAP1	103	107	PF00017	0.437
LIG_SH2_STAP1	27	31	PF00017	0.471
LIG_SH2_STAP1	453	457	PF00017	0.304
LIG_SH2_STAP1	923	927	PF00017	0.304
LIG_SH2_STAT3	78	81	PF00017	0.383
LIG_SH2_STAT5	1060	1063	PF00017	0.378
LIG_SH2_STAT5	130	133	PF00017	0.462
LIG_SH2_STAT5	265	268	PF00017	0.409
LIG_SH2_STAT5	311	314	PF00017	0.496
LIG_SH2_STAT5	332	335	PF00017	0.492
LIG_SH2_STAT5	400	403	PF00017	0.340
LIG_SH2_STAT5	42	45	PF00017	0.423
LIG_SH2_STAT5	443	446	PF00017	0.304
LIG_SH2_STAT5	742	745	PF00017	0.400
LIG_SH2_STAT5	870	873	PF00017	0.440
LIG_SH2_STAT5	905	908	PF00017	0.304
LIG_SH2_STAT5	923	926	PF00017	0.369
LIG_SH2_STAT5	930	933	PF00017	0.343
LIG_SH2_STAT5	962	965	PF00017	0.304
LIG_SH2_STAT5	999	1002	PF00017	0.304
LIG_SH3_3	215	221	PF00018	0.554
LIG_SH3_3	337	343	PF00018	0.461
LIG_SH3_3	57	63	PF00018	0.538
LIG_SH3_3	726	732	PF00018	0.473
LIG_SH3_3	73	79	PF00018	0.578
LIG_SH3_3	780	786	PF00018	0.669
LIG_SH3_3	89	95	PF00018	0.371
LIG_SH3_3	967	973	PF00018	0.304
LIG_Sin3_3	106	113	PF02671	0.481
LIG_SUMO_SIM_anti_2	980	986	PF11976	0.304
LIG_SUMO_SIM_par_1	139	145	PF11976	0.430
LIG_SUMO_SIM_par_1	506	511	PF11976	0.304
LIG_TRAF2_1	648	651	PF00917	0.541
LIG_TRAF2_1	816	819	PF00917	0.647
LIG_TYR_ITIM	903	908	PF00017	0.304
LIG_TYR_ITSM	870	877	PF00017	0.427
LIG_Vh1_VBS_1	1065	1083	PF01044	0.434
LIG_WRC_WIRS_1	129	134	PF05994	0.472
LIG_WRC_WIRS_1	892	897	PF05994	0.435
LIG_WRC_WIRS_1	932	937	PF05994	0.335
MOD_CDK_SPxK_1	869	875	PF00069	0.363
MOD_CK1_1	1068	1074	PF00069	0.399
MOD_CK1_1	200	206	PF00069	0.558
MOD_CK1_1	247	253	PF00069	0.635
MOD_CK1_1	335	341	PF00069	0.455
MOD_CK1_1	56	62	PF00069	0.492
MOD_CK1_1	621	627	PF00069	0.664
MOD_CK1_1	639	645	PF00069	0.701
MOD_CK1_1	685	691	PF00069	0.707
MOD_CK1_1	695	701	PF00069	0.724
MOD_CK2_1	119	125	PF00069	0.585
MOD_CK2_1	645	651	PF00069	0.602
MOD_CK2_1	658	664	PF00069	0.626
MOD_CK2_1	667	673	PF00069	0.663
MOD_GlcNHglycan	1001	1004	PF01048	0.304
MOD_GlcNHglycan	104	107	PF01048	0.437
MOD_GlcNHglycan	111	114	PF01048	0.529
MOD_GlcNHglycan	249	252	PF01048	0.644
MOD_GlcNHglycan	336	340	PF01048	0.493
MOD_GlcNHglycan	4	7	PF01048	0.435
MOD_GlcNHglycan	480	483	PF01048	0.369
MOD_GlcNHglycan	520	523	PF01048	0.594
MOD_GlcNHglycan	630	633	PF01048	0.639
MOD_GlcNHglycan	641	644	PF01048	0.617
MOD_GlcNHglycan	660	663	PF01048	0.623
MOD_GlcNHglycan	669	672	PF01048	0.549
MOD_GlcNHglycan	690	693	PF01048	0.807
MOD_GlcNHglycan	699	702	PF01048	0.685
MOD_GlcNHglycan	745	748	PF01048	0.436
MOD_GlcNHglycan	797	800	PF01048	0.845
MOD_GlcNHglycan	806	809	PF01048	0.590
MOD_GlcNHglycan	98	101	PF01048	0.408
MOD_GSK3_1	256	263	PF00069	0.424
MOD_GSK3_1	499	506	PF00069	0.369
MOD_GSK3_1	52	59	PF00069	0.440
MOD_GSK3_1	542	549	PF00069	0.380
MOD_GSK3_1	618	625	PF00069	0.702
MOD_GSK3_1	62	69	PF00069	0.470
MOD_GSK3_1	638	645	PF00069	0.721
MOD_GSK3_1	663	670	PF00069	0.608
MOD_GSK3_1	688	695	PF00069	0.694
MOD_GSK3_1	720	727	PF00069	0.421
MOD_GSK3_1	791	798	PF00069	0.641
MOD_GSK3_1	890	897	PF00069	0.381
MOD_GSK3_1	987	994	PF00069	0.369
MOD_GSK3_1	999	1006	PF00069	0.257
MOD_N-GLC_1	361	366	PF02516	0.487
MOD_N-GLC_1	618	623	PF02516	0.718
MOD_N-GLC_1	804	809	PF02516	0.634
MOD_N-GLC_1	909	914	PF02516	0.369
MOD_N-GLC_2	318	320	PF02516	0.529
MOD_NEK2_1	1	6	PF00069	0.514
MOD_NEK2_1	1050	1055	PF00069	0.417
MOD_NEK2_1	148	153	PF00069	0.405
MOD_NEK2_1	184	189	PF00069	0.436
MOD_NEK2_1	198	203	PF00069	0.430
MOD_NEK2_1	30	35	PF00069	0.474
MOD_NEK2_1	334	339	PF00069	0.570
MOD_NEK2_1	381	386	PF00069	0.304
MOD_NEK2_1	500	505	PF00069	0.314
MOD_NEK2_1	53	58	PF00069	0.456
MOD_NEK2_1	576	581	PF00069	0.459
MOD_NEK2_1	584	589	PF00069	0.368
MOD_NEK2_1	604	609	PF00069	0.359
MOD_NEK2_1	622	627	PF00069	0.689
MOD_NEK2_1	751	756	PF00069	0.432
MOD_NEK2_1	8	13	PF00069	0.498
MOD_NEK2_1	804	809	PF00069	0.612
MOD_NEK2_2	1003	1008	PF00069	0.369
MOD_NEK2_2	260	265	PF00069	0.384
MOD_NEK2_2	438	443	PF00069	0.304
MOD_NEK2_2	532	537	PF00069	0.434
MOD_PIKK_1	1055	1061	PF00454	0.380
MOD_PIKK_1	245	251	PF00454	0.558
MOD_PIKK_1	300	306	PF00454	0.554
MOD_PIKK_1	327	333	PF00454	0.476
MOD_PIKK_1	546	552	PF00454	0.375
MOD_PIKK_1	685	691	PF00454	0.609
MOD_PIKK_1	695	701	PF00454	0.635
MOD_PIKK_1	791	797	PF00454	0.682
MOD_PIKK_1	947	953	PF00454	0.304
MOD_PKA_1	244	250	PF00069	0.550
MOD_PKA_1	542	548	PF00069	0.399
MOD_PKA_2	158	164	PF00069	0.433
MOD_PKA_2	280	286	PF00069	0.584
MOD_PKA_2	517	523	PF00069	0.504
MOD_PKA_2	53	59	PF00069	0.422
MOD_PKA_2	542	548	PF00069	0.375
MOD_PKA_2	751	757	PF00069	0.345
MOD_PKA_2	921	927	PF00069	0.363
MOD_PKB_1	45	53	PF00069	0.367
MOD_Plk_1	381	387	PF00069	0.304
MOD_Plk_1	636	642	PF00069	0.697
MOD_Plk_4	1068	1074	PF00069	0.399
MOD_Plk_4	260	266	PF00069	0.382
MOD_Plk_4	285	291	PF00069	0.564
MOD_Plk_4	309	315	PF00069	0.494
MOD_Plk_4	348	354	PF00069	0.443
MOD_Plk_4	438	444	PF00069	0.304
MOD_Plk_4	503	509	PF00069	0.308
MOD_Plk_4	53	59	PF00069	0.465
MOD_Plk_4	532	538	PF00069	0.426
MOD_Plk_4	622	628	PF00069	0.676
MOD_Plk_4	737	743	PF00069	0.443
MOD_Plk_4	8	14	PF00069	0.558
MOD_Plk_4	891	897	PF00069	0.378
MOD_ProDKin_1	111	117	PF00069	0.419
MOD_ProDKin_1	56	62	PF00069	0.521
MOD_ProDKin_1	682	688	PF00069	0.718
MOD_ProDKin_1	693	699	PF00069	0.773
MOD_ProDKin_1	775	781	PF00069	0.804
MOD_ProDKin_1	782	788	PF00069	0.610
MOD_ProDKin_1	869	875	PF00069	0.363
MOD_ProDKin_1	91	97	PF00069	0.433
MOD_SUMO_rev_2	283	289	PF00179	0.533
MOD_SUMO_rev_2	316	325	PF00179	0.503
MOD_SUMO_rev_2	990	998	PF00179	0.304
TRG_DiLeu_BaEn_1	382	387	PF01217	0.304
TRG_DiLeu_BaEn_1	70	75	PF01217	0.492
TRG_DiLeu_BaEn_2	484	490	PF01217	0.369
TRG_DiLeu_BaEn_4	382	388	PF01217	0.304
TRG_DiLeu_BaLyEn_6	1009	1014	PF01217	0.314
TRG_DiLeu_BaLyEn_6	453	458	PF01217	0.304
TRG_DiLeu_BaLyEn_6	536	541	PF01217	0.461
TRG_DiLeu_BaLyEn_6	679	684	PF01217	0.539
TRG_DiLeu_BaLyEn_6	951	956	PF01217	0.304
TRG_DiLeu_LyEn_5	382	387	PF01217	0.304
TRG_ENDOCYTIC_2	1004	1007	PF00928	0.304
TRG_ENDOCYTIC_2	27	30	PF00928	0.469
TRG_ENDOCYTIC_2	311	314	PF00928	0.496
TRG_ENDOCYTIC_2	390	393	PF00928	0.369
TRG_ENDOCYTIC_2	874	877	PF00928	0.398
TRG_ENDOCYTIC_2	905	908	PF00928	0.304
TRG_ENDOCYTIC_2	930	933	PF00928	0.331
TRG_ER_diArg_1	353	355	PF00400	0.529
TRG_ER_diArg_1	44	47	PF00400	0.379
TRG_ER_diArg_1	458	460	PF00400	0.325
TRG_ER_diArg_1	51	54	PF00400	0.370
TRG_ER_diArg_1	541	543	PF00400	0.457
TRG_ER_diArg_1	676	678	PF00400	0.593
TRG_NES_CRM1_1	499	511	PF08389	0.304
TRG_NES_CRM1_1	887	901	PF08389	0.446
TRG_NLS_Bipartite_1	542	561	PF00514	0.329
TRG_Pf-PMV_PEXEL_1	456	461	PF00026	0.304
TRG_Pf-PMV_PEXEL_1	542	546	PF00026	0.422
TRG_Pf-PMV_PEXEL_1	574	578	PF00026	0.419
TRG_Pf-PMV_PEXEL_1	954	959	PF00026	0.304

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P435	Leptomonas seymouri	60%	96%
A0A3Q8IGA3	Leishmania donovani	95%	100%
A4HDR3	Leishmania braziliensis	85%	100%
A4I109	Leishmania infantum	95%	100%
E9AX47	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%