LeishMANIAdb
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DUF4142 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF4142 domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4QAB5_LEIMA
TriTrypDb:
LmjF.24.2150 , LMJLV39_240029300 , LMJSD75_240028600
Length:
111

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QAB5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAB5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 6 8 PF00675 0.720
DOC_MAPK_gen_1 13 21 PF00069 0.680
DOC_USP7_MATH_1 17 21 PF00917 0.625
DOC_USP7_UBL2_3 14 18 PF12436 0.636
DOC_WW_Pin1_4 6 11 PF00397 0.564
LIG_14-3-3_CanoR_1 63 67 PF00244 0.691
LIG_deltaCOP1_diTrp_1 79 87 PF00928 0.601
LIG_FHA_1 90 96 PF00498 0.624
LIG_FHA_2 37 43 PF00498 0.581
LIG_SH2_STAT5 86 89 PF00017 0.628
MOD_CDK_SPxxK_3 6 13 PF00069 0.565
MOD_CK1_1 101 107 PF00069 0.572
MOD_CK1_1 6 12 PF00069 0.757
MOD_CK1_1 65 71 PF00069 0.760
MOD_CK2_1 17 23 PF00069 0.560
MOD_CK2_1 36 42 PF00069 0.495
MOD_GSK3_1 61 68 PF00069 0.691
MOD_NEK2_1 61 66 PF00069 0.679
MOD_PIKK_1 46 52 PF00454 0.718
MOD_PKA_2 62 68 PF00069 0.682
MOD_Plk_1 98 104 PF00069 0.593
MOD_Plk_2-3 51 57 PF00069 0.667
MOD_ProDKin_1 6 12 PF00069 0.565

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IBH9 Leishmania donovani 86% 77%
A4HDS6 Leishmania braziliensis 54% 77%
A4I124 Leishmania infantum 87% 77%
E9AX61 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 78%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS