General transcription and DNA repair factor IIH helicase subunit XPD

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

TFIIH basal transcription factor complex helicase subunit, putative

Species:

Leishmania major

UniProt:

Q4QAA2_LEIMA

TriTrypDb:

LmjF.24.2280 , LMJLV39_240030700 , LMJSD75_240030000

Length:

813

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4QAA2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QAA2

Function

Biological processes
Term	Name	Level	Count
GO:0000018	regulation of DNA recombination	6	2
GO:0000019	regulation of mitotic recombination	7	2
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	9	2
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006351	DNA-templated transcription	7	2
GO:0006366	transcription by RNA polymerase II	8	2
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006996	organelle organization	4	2
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	2
GO:0009059	macromolecule biosynthetic process	4	2
GO:0009893	positive regulation of metabolic process	4	2
GO:0009987	cellular process	1	12
GO:0010604	positive regulation of macromolecule metabolic process	5	2
GO:0016043	cellular component organization	3	2
GO:0016070	RNA metabolic process	5	2
GO:0018130	heterocycle biosynthetic process	4	2
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	2
GO:0019222	regulation of metabolic process	3	2
GO:0019438	aromatic compound biosynthetic process	4	2
GO:0031323	regulation of cellular metabolic process	4	2
GO:0031325	positive regulation of cellular metabolic process	5	2
GO:0032392	DNA geometric change	7	2
GO:0032508	DNA duplex unwinding	8	2
GO:0032774	RNA biosynthetic process	5	2
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034654	nucleobase-containing compound biosynthetic process	4	2
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	2
GO:0044271	cellular nitrogen compound biosynthetic process	4	2
GO:0045911	positive regulation of DNA recombination	7	2
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	6	2
GO:0045951	positive regulation of mitotic recombination	8	2
GO:0046483	heterocycle metabolic process	3	12
GO:0048518	positive regulation of biological process	3	2
GO:0048522	positive regulation of cellular process	4	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0051052	regulation of DNA metabolic process	5	2
GO:0051054	positive regulation of DNA metabolic process	6	2
GO:0051171	regulation of nitrogen compound metabolic process	4	2
GO:0051173	positive regulation of nitrogen compound metabolic process	5	2
GO:0051276	chromosome organization	5	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0071103	DNA conformation change	6	2
GO:0071704	organic substance metabolic process	2	12
GO:0071840	cellular component organization or biogenesis	2	2
GO:0080090	regulation of primary metabolic process	4	2
GO:0090304	nucleic acid metabolic process	4	12
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	2
GO:0097659	nucleic acid-templated transcription	6	2
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901362	organic cyclic compound biosynthetic process	4	2
GO:1901576	organic substance biosynthetic process	3	2
GO:0006259	DNA metabolic process	4	10
GO:0006281	DNA repair	5	10
GO:0006289	nucleotide-excision repair	6	10
GO:0006950	response to stress	2	10
GO:0006974	DNA damage response	4	10
GO:0033554	cellular response to stress	3	10
GO:0044260	obsolete cellular macromolecule metabolic process	3	10
GO:0050896	response to stimulus	1	10
GO:0051716	cellular response to stimulus	2	10

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003684	damaged DNA binding	5	2
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016462	pyrophosphatase activity	5	8
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	8
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	8
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.466
CLV_C14_Caspase3-7	242	246	PF00656	0.509
CLV_C14_Caspase3-7	539	543	PF00656	0.455
CLV_NRD_NRD_1	145	147	PF00675	0.233
CLV_NRD_NRD_1	185	187	PF00675	0.250
CLV_NRD_NRD_1	486	488	PF00675	0.400
CLV_NRD_NRD_1	594	596	PF00675	0.266
CLV_NRD_NRD_1	67	69	PF00675	0.396
CLV_NRD_NRD_1	753	755	PF00675	0.562
CLV_NRD_NRD_1	803	805	PF00675	0.673
CLV_NRD_NRD_1	87	89	PF00675	0.124
CLV_PCSK_KEX2_1	145	147	PF00082	0.233
CLV_PCSK_KEX2_1	29	31	PF00082	0.486
CLV_PCSK_KEX2_1	594	596	PF00082	0.266
CLV_PCSK_KEX2_1	67	69	PF00082	0.392
CLV_PCSK_KEX2_1	691	693	PF00082	0.255
CLV_PCSK_KEX2_1	753	755	PF00082	0.579
CLV_PCSK_KEX2_1	805	807	PF00082	0.647
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.486
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.408
CLV_PCSK_PC1ET2_1	691	693	PF00082	0.276
CLV_PCSK_PC1ET2_1	805	807	PF00082	0.647
CLV_PCSK_SKI1_1	135	139	PF00082	0.266
CLV_PCSK_SKI1_1	186	190	PF00082	0.259
CLV_PCSK_SKI1_1	212	216	PF00082	0.341
CLV_PCSK_SKI1_1	373	377	PF00082	0.301
CLV_PCSK_SKI1_1	569	573	PF00082	0.260
CLV_PCSK_SKI1_1	574	578	PF00082	0.234
CLV_PCSK_SKI1_1	692	696	PF00082	0.255
CLV_PCSK_SKI1_1	726	730	PF00082	0.399
CLV_PCSK_SKI1_1	88	92	PF00082	0.266
CLV_Separin_Metazoa	640	644	PF03568	0.455
DEG_APCC_DBOX_1	185	193	PF00400	0.506
DEG_APCC_KENBOX_2	249	253	PF00400	0.347
DEG_Kelch_actinfilin_1	491	495	PF01344	0.400
DEG_Nend_UBRbox_1	1	4	PF02207	0.365
DEG_SCF_FBW7_1	471	478	PF00400	0.442
DOC_CDC14_PxL_1	629	637	PF14671	0.455
DOC_CYCLIN_RxL_1	102	110	PF00134	0.528
DOC_CYCLIN_RxL_1	370	378	PF00134	0.496
DOC_CYCLIN_RxL_1	466	474	PF00134	0.357
DOC_MAPK_DCC_7	186	194	PF00069	0.541
DOC_MAPK_DCC_7	487	495	PF00069	0.359
DOC_MAPK_gen_1	186	194	PF00069	0.466
DOC_MAPK_gen_1	353	362	PF00069	0.455
DOC_MAPK_gen_1	408	417	PF00069	0.400
DOC_MAPK_gen_1	487	495	PF00069	0.367
DOC_MAPK_gen_1	569	578	PF00069	0.541
DOC_MAPK_gen_1	610	619	PF00069	0.455
DOC_MAPK_gen_1	643	651	PF00069	0.516
DOC_MAPK_gen_1	678	687	PF00069	0.455
DOC_MAPK_HePTP_8	184	196	PF00069	0.516
DOC_MAPK_HePTP_8	677	689	PF00069	0.455
DOC_MAPK_MEF2A_6	186	194	PF00069	0.517
DOC_MAPK_MEF2A_6	34	42	PF00069	0.439
DOC_MAPK_MEF2A_6	48	57	PF00069	0.260
DOC_MAPK_MEF2A_6	645	653	PF00069	0.516
DOC_MAPK_MEF2A_6	680	689	PF00069	0.455
DOC_MIT_MIM_1	365	375	PF04212	0.516
DOC_PP1_RVXF_1	325	332	PF00149	0.466
DOC_PP1_RVXF_1	467	474	PF00149	0.367
DOC_PP1_RVXF_1	572	578	PF00149	0.455
DOC_PP2B_LxvP_1	158	161	PF13499	0.541
DOC_PP2B_LxvP_1	40	43	PF13499	0.373
DOC_PP4_FxxP_1	630	633	PF00568	0.455
DOC_PP4_FxxP_1	634	637	PF00568	0.455
DOC_USP7_MATH_1	205	209	PF00917	0.541
DOC_USP7_MATH_1	528	532	PF00917	0.425
DOC_USP7_MATH_1	560	564	PF00917	0.537
DOC_USP7_UBL2_3	250	254	PF12436	0.426
DOC_WW_Pin1_4	459	464	PF00397	0.361
DOC_WW_Pin1_4	471	476	PF00397	0.273
LIG_14-3-3_CanoR_1	135	140	PF00244	0.455
LIG_14-3-3_CanoR_1	338	344	PF00244	0.459
LIG_14-3-3_CanoR_1	450	455	PF00244	0.487
LIG_14-3-3_CanoR_1	497	504	PF00244	0.495
LIG_14-3-3_CanoR_1	667	676	PF00244	0.461
LIG_14-3-3_CanoR_1	678	687	PF00244	0.443
LIG_14-3-3_CanoR_1	757	765	PF00244	0.642
LIG_Actin_WH2_2	249	266	PF00022	0.478
LIG_Actin_WH2_2	429	447	PF00022	0.381
LIG_APCC_ABBA_1	1	6	PF00400	0.415
LIG_BRCT_BRCA1_1	477	481	PF00533	0.430
LIG_BRCT_BRCA1_1	562	566	PF00533	0.541
LIG_Clathr_ClatBox_1	575	579	PF01394	0.455
LIG_EH1_1	682	690	PF00400	0.455
LIG_eIF4E_1	387	393	PF01652	0.522
LIG_eIF4E_1	4	10	PF01652	0.441
LIG_eIF4E_1	553	559	PF01652	0.466
LIG_eIF4E_1	683	689	PF01652	0.466
LIG_FHA_1	217	223	PF00498	0.480
LIG_FHA_1	330	336	PF00498	0.463
LIG_FHA_1	376	382	PF00498	0.511
LIG_FHA_1	433	439	PF00498	0.449
LIG_FHA_1	47	53	PF00498	0.350
LIG_FHA_1	472	478	PF00498	0.415
LIG_FHA_1	578	584	PF00498	0.455
LIG_FHA_1	72	78	PF00498	0.455
LIG_FHA_1	742	748	PF00498	0.516
LIG_FHA_2	240	246	PF00498	0.445
LIG_FHA_2	503	509	PF00498	0.537
LIG_FHA_2	537	543	PF00498	0.462
LIG_FHA_2	74	80	PF00498	0.455
LIG_FHA_2	783	789	PF00498	0.695
LIG_FHA_2	81	87	PF00498	0.455
LIG_IRF3_LxIS_1	651	656	PF10401	0.541
LIG_LIR_Apic_2	15	19	PF02991	0.366
LIG_LIR_Apic_2	406	412	PF02991	0.453
LIG_LIR_Gen_1	198	207	PF02991	0.455
LIG_LIR_Gen_1	274	283	PF02991	0.456
LIG_LIR_Gen_1	526	537	PF02991	0.352
LIG_LIR_Gen_1	549	559	PF02991	0.455
LIG_LIR_LC3C_4	6	11	PF02991	0.472
LIG_LIR_Nem_3	274	278	PF02991	0.456
LIG_LIR_Nem_3	363	368	PF02991	0.541
LIG_LIR_Nem_3	465	470	PF02991	0.399
LIG_LIR_Nem_3	526	532	PF02991	0.359
LIG_LIR_Nem_3	657	663	PF02991	0.459
LIG_LYPXL_S_1	466	470	PF13949	0.355
LIG_LYPXL_SIV_4	181	189	PF13949	0.466
LIG_LYPXL_yS_3	467	470	PF13949	0.358
LIG_MYND_1	633	637	PF01753	0.455
LIG_NRBOX	371	377	PF00104	0.496
LIG_PCNA_PIPBox_1	87	96	PF02747	0.541
LIG_Pex14_2	630	634	PF04695	0.455
LIG_REV1ctd_RIR_1	726	734	PF16727	0.411
LIG_SH2_CRK	150	154	PF00017	0.533
LIG_SH2_CRK	275	279	PF00017	0.466
LIG_SH2_CRK	387	391	PF00017	0.505
LIG_SH2_CRK	397	401	PF00017	0.445
LIG_SH2_NCK_1	409	413	PF00017	0.443
LIG_SH2_PTP2	16	19	PF00017	0.355
LIG_SH2_SRC	14	17	PF00017	0.377
LIG_SH2_SRC	59	62	PF00017	0.389
LIG_SH2_STAP1	14	18	PF00017	0.373
LIG_SH2_STAP1	150	154	PF00017	0.533
LIG_SH2_STAP1	275	279	PF00017	0.455
LIG_SH2_STAP1	529	533	PF00017	0.347
LIG_SH2_STAT3	18	21	PF00017	0.345
LIG_SH2_STAT5	16	19	PF00017	0.296
LIG_SH2_STAT5	183	186	PF00017	0.451
LIG_SH2_STAT5	199	202	PF00017	0.427
LIG_SH2_STAT5	24	27	PF00017	0.162
LIG_SH2_STAT5	343	346	PF00017	0.455
LIG_SH2_STAT5	367	370	PF00017	0.466
LIG_SH2_STAT5	397	400	PF00017	0.486
LIG_SH2_STAT5	4	7	PF00017	0.413
LIG_SH2_STAT5	404	407	PF00017	0.442
LIG_SH2_STAT5	59	62	PF00017	0.354
LIG_SH2_STAT5	72	75	PF00017	0.455
LIG_SH3_3	294	300	PF00018	0.484
LIG_SH3_3	341	347	PF00018	0.455
LIG_SH3_3	420	426	PF00018	0.419
LIG_SH3_3	630	636	PF00018	0.455
LIG_SH3_3	7	13	PF00018	0.343
LIG_SH3_3	777	783	PF00018	0.675
LIG_SH3_3	793	799	PF00018	0.520
LIG_Sin3_3	521	528	PF02671	0.508
LIG_SUMO_SIM_anti_2	219	225	PF11976	0.480
LIG_SUMO_SIM_anti_2	49	54	PF11976	0.339
LIG_SUMO_SIM_anti_2	6	12	PF11976	0.384
LIG_SUMO_SIM_par_1	217	225	PF11976	0.481
LIG_SUMO_SIM_par_1	48	54	PF11976	0.398
LIG_SUMO_SIM_par_1	491	496	PF11976	0.346
LIG_SUMO_SIM_par_1	685	690	PF11976	0.455
LIG_TRAF2_1	505	508	PF00917	0.537
LIG_TRAF2_1	76	79	PF00917	0.466
LIG_TRAF2_1	785	788	PF00917	0.627
LIG_UBA3_1	532	538	PF00899	0.323
LIG_UBA3_1	604	612	PF00899	0.466
LIG_UBA3_1	685	691	PF00899	0.541
LIG_WRC_WIRS_1	765	770	PF05994	0.612
MOD_CK1_1	120	126	PF00069	0.496
MOD_CK1_1	208	214	PF00069	0.518
MOD_CK1_1	498	504	PF00069	0.487
MOD_CK1_1	51	57	PF00069	0.417
MOD_CK1_1	748	754	PF00069	0.481
MOD_CK1_1	778	784	PF00069	0.772
MOD_CK2_1	502	508	PF00069	0.556
MOD_CK2_1	524	530	PF00069	0.402
MOD_CK2_1	653	659	PF00069	0.516
MOD_CK2_1	73	79	PF00069	0.455
MOD_CK2_1	764	770	PF00069	0.668
MOD_CK2_1	782	788	PF00069	0.669
MOD_CK2_1	80	86	PF00069	0.455
MOD_GlcNHglycan	109	112	PF01048	0.289
MOD_GlcNHglycan	368	371	PF01048	0.166
MOD_GlcNHglycan	43	46	PF01048	0.390
MOD_GlcNHglycan	457	460	PF01048	0.346
MOD_GlcNHglycan	526	529	PF01048	0.384
MOD_GlcNHglycan	563	566	PF01048	0.266
MOD_GlcNHglycan	758	761	PF01048	0.607
MOD_GlcNHglycan	800	803	PF01048	0.625
MOD_GSK3_1	116	123	PF00069	0.481
MOD_GSK3_1	235	242	PF00069	0.447
MOD_GSK3_1	398	405	PF00069	0.458
MOD_GSK3_1	450	457	PF00069	0.363
MOD_GSK3_1	471	478	PF00069	0.391
MOD_GSK3_1	498	505	PF00069	0.489
MOD_GSK3_1	524	531	PF00069	0.489
MOD_GSK3_1	741	748	PF00069	0.453
MOD_GSK3_1	764	771	PF00069	0.591
MOD_GSK3_1	778	785	PF00069	0.758
MOD_LATS_1	364	370	PF00433	0.455
MOD_N-GLC_1	502	507	PF02516	0.425
MOD_N-GLC_1	678	683	PF02516	0.255
MOD_N-GLC_1	711	716	PF02516	0.436
MOD_N-GLC_1	775	780	PF02516	0.625
MOD_N-GLC_2	114	116	PF02516	0.255
MOD_NEK2_1	107	112	PF00069	0.480
MOD_NEK2_1	239	244	PF00069	0.480
MOD_NEK2_1	263	268	PF00069	0.455
MOD_NEK2_1	360	365	PF00069	0.518
MOD_NEK2_1	375	380	PF00069	0.452
MOD_NEK2_1	444	449	PF00069	0.451
MOD_NEK2_1	481	486	PF00069	0.389
MOD_NEK2_1	524	529	PF00069	0.425
MOD_NEK2_1	536	541	PF00069	0.395
MOD_NEK2_1	577	582	PF00069	0.455
MOD_NEK2_1	742	747	PF00069	0.445
MOD_NEK2_1	758	763	PF00069	0.507
MOD_NEK2_1	768	773	PF00069	0.641
MOD_NEK2_1	80	85	PF00069	0.466
MOD_PIKK_1	577	583	PF00454	0.455
MOD_PIKK_1	667	673	PF00454	0.455
MOD_PK_1	450	456	PF00069	0.379
MOD_PKA_1	243	249	PF00069	0.604
MOD_PKA_2	337	343	PF00069	0.459
MOD_PKA_2	444	450	PF00069	0.504
MOD_PKA_2	496	502	PF00069	0.444
MOD_PKA_2	756	762	PF00069	0.577
MOD_Plk_1	117	123	PF00069	0.503
MOD_Plk_1	216	222	PF00069	0.480
MOD_Plk_1	360	366	PF00069	0.487
MOD_Plk_1	438	444	PF00069	0.347
MOD_Plk_1	583	589	PF00069	0.467
MOD_Plk_1	714	720	PF00069	0.397
MOD_Plk_1	775	781	PF00069	0.759
MOD_Plk_4	195	201	PF00069	0.455
MOD_Plk_4	216	222	PF00069	0.475
MOD_Plk_4	235	241	PF00069	0.350
MOD_Plk_4	346	352	PF00069	0.457
MOD_Plk_4	395	401	PF00069	0.494
MOD_Plk_4	51	57	PF00069	0.338
MOD_Plk_4	528	534	PF00069	0.408
MOD_Plk_4	742	748	PF00069	0.440
MOD_ProDKin_1	459	465	PF00069	0.369
MOD_ProDKin_1	471	477	PF00069	0.268
MOD_SUMO_for_1	354	357	PF00179	0.496
MOD_SUMO_for_1	783	786	PF00179	0.728
MOD_SUMO_rev_2	166	173	PF00179	0.470
TRG_AP2beta_CARGO_1	657	667	PF09066	0.541
TRG_DiLeu_BaEn_1	235	240	PF01217	0.466
TRG_DiLeu_BaEn_1	274	279	PF01217	0.455
TRG_DiLeu_BaEn_1	292	297	PF01217	0.455
TRG_DiLeu_BaEn_1	86	91	PF01217	0.466
TRG_DiLeu_BaEn_2	409	415	PF01217	0.404
TRG_ENDOCYTIC_2	14	17	PF00928	0.377
TRG_ENDOCYTIC_2	150	153	PF00928	0.533
TRG_ENDOCYTIC_2	182	185	PF00928	0.480
TRG_ENDOCYTIC_2	199	202	PF00928	0.480
TRG_ENDOCYTIC_2	275	278	PF00928	0.455
TRG_ENDOCYTIC_2	387	390	PF00928	0.505
TRG_ENDOCYTIC_2	397	400	PF00928	0.445
TRG_ENDOCYTIC_2	467	470	PF00928	0.358
TRG_ENDOCYTIC_2	529	532	PF00928	0.352
TRG_ENDOCYTIC_2	551	554	PF00928	0.445
TRG_ENDOCYTIC_2	683	686	PF00928	0.455
TRG_ENDOCYTIC_2	765	768	PF00928	0.686
TRG_ER_diArg_1	593	595	PF00400	0.466
TRG_ER_diArg_1	642	645	PF00400	0.455
TRG_ER_diArg_1	752	754	PF00400	0.562
TRG_NES_CRM1_1	427	439	PF08389	0.499
TRG_NES_CRM1_1	644	659	PF08389	0.455
TRG_NLS_MonoCore_2	803	808	PF00514	0.724
TRG_NLS_MonoExtC_3	803	808	PF00514	0.645
TRG_Pf-PMV_PEXEL_1	294	298	PF00026	0.298
TRG_Pf-PMV_PEXEL_1	704	708	PF00026	0.341

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K3	Leptomonas seymouri	25%	85%
A0A0N1PBH5	Leptomonas seymouri	89%	100%
A0A0P0V4R0	Oryza sativa subsp. japonica	23%	80%
A0A0S4KNN1	Bodo saltans	67%	100%
A0A1X0NWG0	Trypanosomatidae	74%	99%
A0A3R7REL5	Trypanosoma rangeli	74%	100%
A0A3S7WYU3	Leishmania donovani	97%	100%
A0A3S7X2X3	Leishmania donovani	25%	85%
A4HDT9	Leishmania braziliensis	94%	100%
A4HHR4	Leishmania braziliensis	24%	85%
A4I136	Leishmania infantum	97%	100%
A4I4X4	Leishmania infantum	25%	85%
A4K436	Bos taurus	25%	67%
A6QLJ0	Bos taurus	44%	100%
A8MPP1	Homo sapiens	21%	90%
A8WS58	Caenorhabditis briggsae	24%	82%
B0W9F4	Culex quinquefasciatus	24%	83%
B3MSG8	Drosophila ananassae	24%	82%
B3NSW1	Drosophila erecta	25%	83%
B4I0K4	Drosophila sechellia	24%	84%
B4JNS2	Drosophila grimshawi	25%	82%
B4L1Z2	Drosophila mojavensis	25%	80%
B4M891	Drosophila virilis	25%	81%
B4PZB4	Drosophila yakuba	25%	83%
C9ZW71	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	99%
E9AEC8	Leishmania major	24%	85%
E9ALF8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	85%
E9AX74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
F4HQE2	Arabidopsis thaliana	23%	78%
O08811	Mus musculus	44%	100%
P06839	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P0C928	Danio rerio	24%	69%
P18074	Homo sapiens	43%	100%
P26659	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
Q16X92	Aedes aegypti	24%	80%
Q55G81	Dictyostelium discoideum	39%	100%
Q5SXJ3	Mus musculus	24%	69%
Q60452	Cricetulus griseus	44%	100%
Q6AXC6	Mus musculus	21%	90%
Q6BZD9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	99%
Q7QEI1	Anopheles gambiae	24%	82%
Q8W4M7	Arabidopsis thaliana	41%	100%
Q92771	Homo sapiens	21%	86%
Q93575	Caenorhabditis elegans	24%	82%
Q96FC9	Homo sapiens	21%	84%
Q9NZ71	Homo sapiens	23%	67%
V5B587	Trypanosoma cruzi	74%	100%