LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QA65_LEIMA
TriTrypDb:
LmjF.25.0305 , LMJLV39_250008500 * , LMJSD75_250008500 *
Length:
90

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QA65
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA65

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 46 48 PF00675 0.604
CLV_NRD_NRD_1 87 89 PF00675 0.415
CLV_PCSK_FUR_1 85 89 PF00082 0.405
CLV_PCSK_KEX2_1 46 48 PF00082 0.604
CLV_PCSK_KEX2_1 87 89 PF00082 0.392
CLV_PCSK_SKI1_1 11 15 PF00082 0.640
CLV_PCSK_SKI1_1 34 38 PF00082 0.660
DEG_APCC_DBOX_1 45 53 PF00400 0.420
DOC_MAPK_gen_1 46 53 PF00069 0.402
DOC_MAPK_MEF2A_6 46 55 PF00069 0.359
DOC_USP7_UBL2_3 25 29 PF12436 0.509
DOC_WW_Pin1_4 24 29 PF00397 0.487
DOC_WW_Pin1_4 39 44 PF00397 0.452
LIG_BIR_II_1 1 5 PF00653 0.483
LIG_FHA_1 10 16 PF00498 0.442
LIG_FHA_2 12 18 PF00498 0.488
LIG_FHA_2 40 46 PF00498 0.387
LIG_SH2_CRK 80 84 PF00017 0.541
LIG_SUMO_SIM_par_1 9 23 PF11976 0.453
LIG_TYR_ITIM 78 83 PF00017 0.451
MOD_CDK_SPK_2 24 29 PF00069 0.480
MOD_CDK_SPxxK_3 39 46 PF00069 0.446
MOD_CK1_1 23 29 PF00069 0.500
MOD_CK2_1 11 17 PF00069 0.514
MOD_CK2_1 24 30 PF00069 0.500
MOD_CK2_1 39 45 PF00069 0.396
MOD_GlcNHglycan 1 4 PF01048 0.734
MOD_GlcNHglycan 22 25 PF01048 0.717
MOD_GlcNHglycan 30 34 PF01048 0.603
MOD_GlcNHglycan 74 77 PF01048 0.383
MOD_GSK3_1 16 23 PF00069 0.498
MOD_Plk_1 9 15 PF00069 0.505
MOD_ProDKin_1 24 30 PF00069 0.485
MOD_ProDKin_1 39 45 PF00069 0.448
TRG_DiLeu_BaEn_1 45 50 PF01217 0.368
TRG_ENDOCYTIC_2 80 83 PF00928 0.564
TRG_ER_diArg_1 85 88 PF00400 0.576

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7W7 Leptomonas seymouri 45% 87%
A0A3Q8ID69 Leishmania donovani 88% 100%
A4I173 Leishmania infantum 87% 100%
E9AIR4 Leishmania braziliensis 60% 100%
E9AXA7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS