Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QA62_LEIMA

TriTrypDb:

LmjF.25.0330 , LMJLV39_250008800 , LMJSD75_250008800

Length:

685

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Show entries

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	3
GO:0043226	organelle	2	3
GO:0043228	non-membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043232	intracellular non-membrane-bounded organelle	4	3
GO:0110165	cellular anatomical entity	1	3

Previous1Next

Expansion

Sequence features

Q4QA62

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA62

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	3
GO:0006518	peptide metabolic process	4	3
GO:0006807	nitrogen compound metabolic process	2	3
GO:0008152	metabolic process	1	3
GO:0009058	biosynthetic process	2	3
GO:0009059	macromolecule biosynthetic process	4	3
GO:0009987	cellular process	1	3
GO:0019538	protein metabolic process	3	3
GO:0034641	cellular nitrogen compound metabolic process	3	3
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	3

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	3
GO:0005198	structural molecule activity	1	3

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	502	506	PF00656	0.494
CLV_NRD_NRD_1	342	344	PF00675	0.685
CLV_NRD_NRD_1	346	348	PF00675	0.662
CLV_NRD_NRD_1	364	366	PF00675	0.588
CLV_NRD_NRD_1	383	385	PF00675	0.434
CLV_NRD_NRD_1	423	425	PF00675	0.663
CLV_NRD_NRD_1	457	459	PF00675	0.705
CLV_NRD_NRD_1	562	564	PF00675	0.718
CLV_NRD_NRD_1	573	575	PF00675	0.472
CLV_PCSK_FUR_1	560	564	PF00082	0.685

Previous1 2 3 4 5…27Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WYR3	Leishmania donovani	89%	100%
A4HDY0	Leishmania braziliensis	69%	98%
A4I176	Leishmania infantum	89%	100%
E9AXB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%

Previous1Next