Raptor_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Regulatory-associated protein of TOR1

Species:

Leishmania major

UniProt:

Q4QA34_LEIMA

TriTrypDb:

LmjF.25.0610 , LMJLV39_250012000 , LMJSD75_250011900

Length:

1471

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0031931	TORC1 complex	4	8
GO:0032991	protein-containing complex	1	8
GO:0038201	TOR complex	3	8
GO:0110165	cellular anatomical entity	1	2
GO:0140535	intracellular protein-containing complex	2	8

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Expansion

Sequence features

Q4QA34

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0001101	response to acid chemical	3	2
GO:0001558	regulation of cell growth	4	2
GO:0001932	regulation of protein phosphorylation	7	2
GO:0001934	positive regulation of protein phosphorylation	8	2
GO:0006950	response to stress	2	2
GO:0007154	cell communication	2	2
GO:0007165	signal transduction	2	8
GO:0008361	regulation of cell size	5	2
GO:0009267	cellular response to starvation	4	2
GO:0009605	response to external stimulus	2	2

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Molecular functions
Term	Name	Level	Count
GO:0030674	protein-macromolecule adaptor activity	2	2
GO:0060090	molecular adaptor activity	1	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	638	642	PF00656	0.560
CLV_NRD_NRD_1	1026	1028	PF00675	0.504
CLV_NRD_NRD_1	1033	1035	PF00675	0.527
CLV_NRD_NRD_1	11	13	PF00675	0.654
CLV_NRD_NRD_1	1321	1323	PF00675	0.454
CLV_NRD_NRD_1	211	213	PF00675	0.359
CLV_NRD_NRD_1	356	358	PF00675	0.502
CLV_NRD_NRD_1	5	7	PF00675	0.653
CLV_NRD_NRD_1	817	819	PF00675	0.424
CLV_PCSK_FUR_1	621	625	PF00082	0.707

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P678	Leptomonas seymouri	74%	97%
A0A3S7WYY1	Leishmania donovani	95%	100%
A4HEF7	Leishmania braziliensis	86%	100%
A4I1A2	Leishmania infantum	95%	100%
E9AXD8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5DP89	Trypanosoma cruzi	50%	100%

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