Mediator of RNA polymerase II transcription subunit 21

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QA31_LEIMA

TriTrypDb:

LmjF.25.0640 , LMJLV39_250012300 , LMJSD75_250012200

Length:

162


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

Q4QA31

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA31


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	134	136	PF00675	0.473
CLV_NRD_NRD_1	76	78	PF00675	0.592
CLV_NRD_NRD_1	83	85	PF00675	0.552
CLV_PCSK_KEX2_1	134	136	PF00082	0.529
CLV_PCSK_KEX2_1	75	77	PF00082	0.600
CLV_PCSK_KEX2_1	83	85	PF00082	0.545
CLV_PCSK_SKI1_1	90	94	PF00082	0.563
CLV_Separin_Metazoa	80	84	PF03568	0.430
DOC_USP7_MATH_1	126	130	PF00917	0.475
LIG_Actin_WH2_2	79	96	PF00022	0.411
LIG_APCC_ABBA_1	137	142	PF00400	0.516
LIG_BIR_II_1	1	5	PF00653	0.441
LIG_BIR_III_2	29	33	PF00653	0.494
LIG_BIR_III_4	105	109	PF00653	0.543
LIG_eIF4E_1	140	146	PF01652	0.410
LIG_FHA_2	146	152	PF00498	0.517
LIG_FHA_2	69	75	PF00498	0.543
LIG_LIR_Gen_1	11	19	PF02991	0.355
LIG_LIR_Nem_3	11	16	PF02991	0.359
LIG_Rb_pABgroove_1	134	142	PF01858	0.520
LIG_SH2_CRK	13	17	PF00017	0.484
LIG_SH2_NCK_1	140	144	PF00017	0.381
LIG_SH2_SRC	13	16	PF00017	0.359
LIG_SH2_SRC	140	143	PF00017	0.383
LIG_SH2_STAP1	13	17	PF00017	0.357
LIG_SH2_STAP1	140	144	PF00017	0.513
LIG_SH2_STAT5	15	18	PF00017	0.471
LIG_SUMO_SIM_par_1	112	119	PF11976	0.567
LIG_SUMO_SIM_par_1	135	142	PF11976	0.518
MOD_CK2_1	145	151	PF00069	0.481
MOD_CK2_1	68	74	PF00069	0.490
MOD_Cter_Amidation	132	135	PF01082	0.528
MOD_GlcNHglycan	105	109	PF01048	0.550
MOD_GlcNHglycan	128	131	PF01048	0.544
MOD_NEK2_1	145	150	PF00069	0.553
MOD_NEK2_1	155	160	PF00069	0.566
MOD_PKA_2	68	74	PF00069	0.569
MOD_Plk_4	31	37	PF00069	0.645
MOD_Plk_4	59	65	PF00069	0.614
TRG_ENDOCYTIC_2	13	16	PF00928	0.487
TRG_ER_diArg_1	134	136	PF00400	0.473
TRG_ER_diArg_1	75	77	PF00400	0.479
TRG_ER_diArg_1	82	84	PF00400	0.469
TRG_Pf-PMV_PEXEL_1	76	80	PF00026	0.489
TRG_Pf-PMV_PEXEL_1	84	89	PF00026	0.377


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P682	Leptomonas seymouri	64%	100%
A0A1X0P4E5	Trypanosomatidae	32%	100%
A0A3Q8IN81	Leishmania donovani	93%	100%
A0A3R7L9Z8	Trypanosoma rangeli	33%	93%
A4HEF4	Leishmania braziliensis	83%	100%
A4I1A5	Leishmania infantum	93%	100%
D0A5J7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AXE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5B7Q6	Trypanosoma cruzi	33%	100%