Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QA26_LEIMA

TriTrypDb:

LmjF.25.0690 , LMJLV39_250012800 , LMJSD75_250012700

Length:

1078

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QA26

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA26

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1063	1067	PF00656	0.691
CLV_C14_Caspase3-7	226	230	PF00656	0.642
CLV_C14_Caspase3-7	279	283	PF00656	0.646
CLV_C14_Caspase3-7	536	540	PF00656	0.734
CLV_C14_Caspase3-7	732	736	PF00656	0.763
CLV_C14_Caspase3-7	769	773	PF00656	0.705
CLV_C14_Caspase3-7	838	842	PF00656	0.658
CLV_MEL_PAP_1	244	250	PF00089	0.676
CLV_NRD_NRD_1	12	14	PF00675	0.545
CLV_NRD_NRD_1	219	221	PF00675	0.636
CLV_NRD_NRD_1	313	315	PF00675	0.715
CLV_NRD_NRD_1	45	47	PF00675	0.690
CLV_NRD_NRD_1	509	511	PF00675	0.727
CLV_NRD_NRD_1	710	712	PF00675	0.563
CLV_NRD_NRD_1	91	93	PF00675	0.678
CLV_NRD_NRD_1	940	942	PF00675	0.686
CLV_PCSK_FUR_1	217	221	PF00082	0.677
CLV_PCSK_FUR_1	507	511	PF00082	0.771
CLV_PCSK_KEX2_1	14	16	PF00082	0.534
CLV_PCSK_KEX2_1	219	221	PF00082	0.631
CLV_PCSK_KEX2_1	313	315	PF00082	0.683
CLV_PCSK_KEX2_1	509	511	PF00082	0.683
CLV_PCSK_KEX2_1	710	712	PF00082	0.553
CLV_PCSK_KEX2_1	91	93	PF00082	0.678
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.534
CLV_PCSK_PC7_1	215	221	PF00082	0.719
CLV_PCSK_SKI1_1	324	328	PF00082	0.665
CLV_PCSK_SKI1_1	46	50	PF00082	0.697
CLV_PCSK_SKI1_1	620	624	PF00082	0.643
CLV_PCSK_SKI1_1	657	661	PF00082	0.510
CLV_PCSK_SKI1_1	91	95	PF00082	0.686
CLV_PCSK_SKI1_1	911	915	PF00082	0.558
CLV_PCSK_SKI1_1	933	937	PF00082	0.690
CLV_PCSK_SKI1_1	979	983	PF00082	0.567
DEG_APCC_DBOX_1	910	918	PF00400	0.561
DEG_Nend_UBRbox_1	1	4	PF02207	0.562
DEG_SCF_TRCP1_1	830	836	PF00400	0.769
DEG_SPOP_SBC_1	489	493	PF00917	0.681
DEG_SPOP_SBC_1	726	730	PF00917	0.806
DOC_CDC14_PxL_1	404	412	PF14671	0.492
DOC_MAPK_DCC_7	313	323	PF00069	0.685
DOC_MAPK_DCC_7	456	465	PF00069	0.654
DOC_MAPK_DCC_7	509	519	PF00069	0.649
DOC_MAPK_gen_1	310	320	PF00069	0.528
DOC_MAPK_gen_1	507	514	PF00069	0.752
DOC_MAPK_gen_1	618	625	PF00069	0.463
DOC_MAPK_HePTP_8	453	465	PF00069	0.642
DOC_MAPK_MEF2A_6	187	196	PF00069	0.710
DOC_MAPK_MEF2A_6	314	323	PF00069	0.689
DOC_MAPK_MEF2A_6	456	465	PF00069	0.638
DOC_MAPK_MEF2A_6	510	519	PF00069	0.646
DOC_MAPK_MEF2A_6	596	604	PF00069	0.589
DOC_MAPK_MEF2A_6	628	636	PF00069	0.467
DOC_PP1_RVXF_1	1068	1075	PF00149	0.761
DOC_PP2B_LxvP_1	405	408	PF13499	0.688
DOC_PP2B_LxvP_1	917	920	PF13499	0.581
DOC_SPAK_OSR1_1	676	680	PF12202	0.600
DOC_USP7_MATH_1	1024	1028	PF00917	0.749
DOC_USP7_MATH_1	1030	1034	PF00917	0.604
DOC_USP7_MATH_1	117	121	PF00917	0.694
DOC_USP7_MATH_1	263	267	PF00917	0.753
DOC_USP7_MATH_1	326	330	PF00917	0.629
DOC_USP7_MATH_1	366	370	PF00917	0.685
DOC_USP7_MATH_1	391	395	PF00917	0.712
DOC_USP7_MATH_1	400	404	PF00917	0.574
DOC_USP7_MATH_1	489	493	PF00917	0.681
DOC_USP7_MATH_1	543	547	PF00917	0.736
DOC_USP7_MATH_1	556	560	PF00917	0.482
DOC_USP7_MATH_1	57	61	PF00917	0.626
DOC_USP7_MATH_1	585	589	PF00917	0.739
DOC_USP7_MATH_1	681	685	PF00917	0.548
DOC_USP7_MATH_1	727	731	PF00917	0.814
DOC_USP7_MATH_1	784	788	PF00917	0.773
DOC_USP7_MATH_1	799	803	PF00917	0.527
DOC_USP7_MATH_1	84	88	PF00917	0.654
DOC_USP7_MATH_1	862	866	PF00917	0.696
DOC_WW_Pin1_4	1012	1017	PF00397	0.784
DOC_WW_Pin1_4	381	386	PF00397	0.783
DOC_WW_Pin1_4	425	430	PF00397	0.669
DOC_WW_Pin1_4	490	495	PF00397	0.646
DOC_WW_Pin1_4	552	557	PF00397	0.681
DOC_WW_Pin1_4	7	12	PF00397	0.547
DOC_WW_Pin1_4	811	816	PF00397	0.792
DOC_WW_Pin1_4	946	951	PF00397	0.658
DOC_WW_Pin1_4	965	970	PF00397	0.394
LIG_14-3-3_CanoR_1	1008	1012	PF00244	0.707
LIG_14-3-3_CanoR_1	118	124	PF00244	0.625
LIG_14-3-3_CanoR_1	247	253	PF00244	0.588
LIG_14-3-3_CanoR_1	275	281	PF00244	0.735
LIG_14-3-3_CanoR_1	328	336	PF00244	0.633
LIG_14-3-3_CanoR_1	344	349	PF00244	0.664
LIG_14-3-3_CanoR_1	419	424	PF00244	0.618
LIG_14-3-3_CanoR_1	523	528	PF00244	0.644
LIG_14-3-3_CanoR_1	805	811	PF00244	0.720
LIG_14-3-3_CanoR_1	843	851	PF00244	0.711
LIG_14-3-3_CanoR_1	933	940	PF00244	0.690
LIG_Actin_WH2_2	147	163	PF00022	0.719
LIG_Actin_WH2_2	398	413	PF00022	0.613
LIG_APCC_ABBA_1	603	608	PF00400	0.536
LIG_BIR_III_2	655	659	PF00653	0.634
LIG_BRCT_BRCA1_1	348	352	PF00533	0.691
LIG_BRCT_BRCA1_1	823	827	PF00533	0.714
LIG_BRCT_BRCA1_1	841	845	PF00533	0.693
LIG_BRCT_BRCA1_1	98	102	PF00533	0.668
LIG_Clathr_ClatBox_1	603	607	PF01394	0.566
LIG_CSL_BTD_1	553	556	PF09270	0.755
LIG_CtBP_PxDLS_1	474	478	PF00389	0.768
LIG_EH1_1	597	605	PF00400	0.577
LIG_eIF4E_1	908	914	PF01652	0.654
LIG_EVH1_2	815	819	PF00568	0.727
LIG_EVH1_2	880	884	PF00568	0.718
LIG_FHA_1	1046	1052	PF00498	0.656
LIG_FHA_1	328	334	PF00498	0.627
LIG_FHA_1	354	360	PF00498	0.583
LIG_FHA_1	60	66	PF00498	0.601
LIG_FHA_1	769	775	PF00498	0.673
LIG_FHA_1	789	795	PF00498	0.461
LIG_FHA_2	111	117	PF00498	0.627
LIG_FHA_2	224	230	PF00498	0.680
LIG_FHA_2	791	797	PF00498	0.566
LIG_FHA_2	848	854	PF00498	0.775
LIG_FHA_2	996	1002	PF00498	0.729
LIG_LIR_Gen_1	1000	1009	PF02991	0.619
LIG_LIR_Gen_1	1026	1036	PF02991	0.623
LIG_LIR_Gen_1	267	277	PF02991	0.672
LIG_LIR_Gen_1	629	638	PF02991	0.551
LIG_LIR_Gen_1	761	767	PF02991	0.699
LIG_LIR_Gen_1	984	990	PF02991	0.578
LIG_LIR_Nem_3	1000	1006	PF02991	0.614
LIG_LIR_Nem_3	1026	1031	PF02991	0.632
LIG_LIR_Nem_3	1033	1038	PF02991	0.605
LIG_LIR_Nem_3	124	129	PF02991	0.577
LIG_LIR_Nem_3	203	208	PF02991	0.585
LIG_LIR_Nem_3	267	273	PF02991	0.633
LIG_LIR_Nem_3	286	292	PF02991	0.610
LIG_LIR_Nem_3	629	634	PF02991	0.451
LIG_LIR_Nem_3	761	766	PF02991	0.701
LIG_LIR_Nem_3	984	988	PF02991	0.578
LIG_LYPXL_SIV_4	1034	1042	PF13949	0.644
LIG_MYND_1	408	412	PF01753	0.683
LIG_MYND_1	816	820	PF01753	0.725
LIG_NRBOX	28	34	PF00104	0.593
LIG_NRBOX	942	948	PF00104	0.626
LIG_Pex14_2	295	299	PF04695	0.608
LIG_Pex14_2	348	352	PF04695	0.527
LIG_Pex14_2	77	81	PF04695	0.569
LIG_Pex14_2	955	959	PF04695	0.548
LIG_Rb_LxCxE_1	355	375	PF01857	0.689
LIG_RPA_C_Fungi	365	377	PF08784	0.554
LIG_RPA_C_Fungi	800	812	PF08784	0.613
LIG_SH2_CRK	205	209	PF00017	0.596
LIG_SH2_GRB2like	193	196	PF00017	0.697
LIG_SH2_NCK_1	1009	1013	PF00017	0.751
LIG_SH2_NCK_1	752	756	PF00017	0.651
LIG_SH2_SRC	725	728	PF00017	0.800
LIG_SH2_SRC	904	907	PF00017	0.671
LIG_SH2_STAP1	177	181	PF00017	0.592
LIG_SH2_STAP1	746	750	PF00017	0.777
LIG_SH2_STAP1	752	756	PF00017	0.694
LIG_SH2_STAT5	1009	1012	PF00017	0.741
LIG_SH2_STAT5	1035	1038	PF00017	0.603
LIG_SH2_STAT5	1073	1076	PF00017	0.753
LIG_SH2_STAT5	129	132	PF00017	0.635
LIG_SH2_STAT5	193	196	PF00017	0.706
LIG_SH2_STAT5	237	240	PF00017	0.636
LIG_SH2_STAT5	297	300	PF00017	0.710
LIG_SH2_STAT5	36	39	PF00017	0.642
LIG_SH2_STAT5	763	766	PF00017	0.623
LIG_SH2_STAT5	967	970	PF00017	0.707
LIG_SH3_1	874	880	PF00018	0.672
LIG_SH3_3	106	112	PF00018	0.730
LIG_SH3_3	144	150	PF00018	0.688
LIG_SH3_3	458	464	PF00018	0.618
LIG_SH3_3	509	515	PF00018	0.650
LIG_SH3_3	542	548	PF00018	0.726
LIG_SH3_3	874	880	PF00018	0.644
LIG_SUMO_SIM_anti_2	355	361	PF11976	0.706
LIG_SUMO_SIM_anti_2	601	608	PF11976	0.575
LIG_SUMO_SIM_par_1	141	146	PF11976	0.549
LIG_SUMO_SIM_par_1	472	479	PF11976	0.768
LIG_SUMO_SIM_par_1	59	66	PF11976	0.632
LIG_SUMO_SIM_par_1	601	608	PF11976	0.575
LIG_SUMO_SIM_par_1	657	663	PF11976	0.561
LIG_TYR_ITIM	983	988	PF00017	0.613
LIG_WRC_WIRS_1	123	128	PF05994	0.707
LIG_WRC_WIRS_1	401	406	PF05994	0.454
LIG_WRC_WIRS_1	420	425	PF05994	0.682
MOD_CDK_SPxK_1	7	13	PF00069	0.547
MOD_CDK_SPxxK_3	7	14	PF00069	0.547
MOD_CK1_1	1064	1070	PF00069	0.721
MOD_CK1_1	19	25	PF00069	0.522
MOD_CK1_1	266	272	PF00069	0.538
MOD_CK1_1	347	353	PF00069	0.734
MOD_CK1_1	381	387	PF00069	0.783
MOD_CK1_1	422	428	PF00069	0.629
MOD_CK1_1	476	482	PF00069	0.728
MOD_CK1_1	490	496	PF00069	0.583
MOD_CK1_1	59	65	PF00069	0.609
MOD_CK1_1	729	735	PF00069	0.822
MOD_CK1_1	787	793	PF00069	0.760
MOD_CK1_1	814	820	PF00069	0.692
MOD_CK1_1	821	827	PF00069	0.726
MOD_CK1_1	831	837	PF00069	0.807
MOD_CK1_1	839	845	PF00069	0.740
MOD_CK1_1	846	852	PF00069	0.459
MOD_CK1_1	87	93	PF00069	0.634
MOD_CK2_1	1012	1018	PF00069	0.587
MOD_CK2_1	110	116	PF00069	0.713
MOD_CK2_1	167	173	PF00069	0.718
MOD_CK2_1	608	614	PF00069	0.592
MOD_CK2_1	832	838	PF00069	0.741
MOD_CK2_1	995	1001	PF00069	0.738
MOD_GlcNHglycan	1032	1035	PF01048	0.607
MOD_GlcNHglycan	1056	1060	PF01048	0.811
MOD_GlcNHglycan	1066	1069	PF01048	0.613
MOD_GlcNHglycan	22	25	PF01048	0.601
MOD_GlcNHglycan	226	229	PF01048	0.693
MOD_GlcNHglycan	248	251	PF01048	0.669
MOD_GlcNHglycan	278	281	PF01048	0.602
MOD_GlcNHglycan	37	40	PF01048	0.615
MOD_GlcNHglycan	380	383	PF01048	0.703
MOD_GlcNHglycan	424	427	PF01048	0.644
MOD_GlcNHglycan	53	56	PF01048	0.493
MOD_GlcNHglycan	531	534	PF01048	0.705
MOD_GlcNHglycan	544	548	PF01048	0.644
MOD_GlcNHglycan	572	575	PF01048	0.760
MOD_GlcNHglycan	589	592	PF01048	0.495
MOD_GlcNHglycan	662	665	PF01048	0.565
MOD_GlcNHglycan	683	686	PF01048	0.683
MOD_GlcNHglycan	701	704	PF01048	0.532
MOD_GlcNHglycan	731	734	PF01048	0.824
MOD_GlcNHglycan	775	779	PF01048	0.677
MOD_GlcNHglycan	781	784	PF01048	0.712
MOD_GlcNHglycan	786	789	PF01048	0.634
MOD_GlcNHglycan	829	833	PF01048	0.761
MOD_GlcNHglycan	846	849	PF01048	0.793
MOD_GlcNHglycan	861	865	PF01048	0.530
MOD_GlcNHglycan	929	932	PF01048	0.656
MOD_GlcNHglycan	956	959	PF01048	0.707
MOD_GSK3_1	1007	1014	PF00069	0.550
MOD_GSK3_1	117	124	PF00069	0.696
MOD_GSK3_1	16	23	PF00069	0.496
MOD_GSK3_1	163	170	PF00069	0.749
MOD_GSK3_1	362	369	PF00069	0.649
MOD_GSK3_1	381	388	PF00069	0.508
MOD_GSK3_1	418	425	PF00069	0.666
MOD_GSK3_1	5	12	PF00069	0.666
MOD_GSK3_1	515	522	PF00069	0.619
MOD_GSK3_1	529	536	PF00069	0.685
MOD_GSK3_1	548	555	PF00069	0.735
MOD_GSK3_1	565	572	PF00069	0.597
MOD_GSK3_1	647	654	PF00069	0.578
MOD_GSK3_1	725	732	PF00069	0.735
MOD_GSK3_1	784	791	PF00069	0.709
MOD_GSK3_1	799	806	PF00069	0.606
MOD_GSK3_1	814	821	PF00069	0.609
MOD_GSK3_1	828	835	PF00069	0.763
MOD_GSK3_1	837	844	PF00069	0.697
MOD_GSK3_1	847	854	PF00069	0.667
MOD_GSK3_1	942	949	PF00069	0.692
MOD_GSK3_1	995	1002	PF00069	0.730
MOD_LATS_1	742	748	PF00433	0.741
MOD_LATS_1	826	832	PF00433	0.755
MOD_N-GLC_1	163	168	PF02516	0.748
MOD_N-GLC_1	378	383	PF02516	0.619
MOD_N-GLC_1	681	686	PF02516	0.671
MOD_N-GLC_1	779	784	PF02516	0.744
MOD_NEK2_1	1045	1050	PF00069	0.647
MOD_NEK2_1	143	148	PF00069	0.714
MOD_NEK2_1	17	22	PF00069	0.751
MOD_NEK2_1	327	332	PF00069	0.682
MOD_NEK2_1	570	575	PF00069	0.629
MOD_NEK2_1	660	665	PF00069	0.504
MOD_NEK2_1	76	81	PF00069	0.625
MOD_NEK2_1	851	856	PF00069	0.612
MOD_NEK2_1	860	865	PF00069	0.587
MOD_NEK2_1	999	1004	PF00069	0.664
MOD_NEK2_2	150	155	PF00069	0.705
MOD_NEK2_2	391	396	PF00069	0.660
MOD_PIKK_1	1061	1067	PF00454	0.740
MOD_PIKK_1	428	434	PF00454	0.800
MOD_PIKK_1	565	571	PF00454	0.733
MOD_PIKK_1	799	805	PF00454	0.733
MOD_PIKK_1	96	102	PF00454	0.669
MOD_PKA_2	1007	1013	PF00069	0.713
MOD_PKA_2	110	116	PF00069	0.667
MOD_PKA_2	117	123	PF00069	0.633
MOD_PKA_2	246	252	PF00069	0.685
MOD_PKA_2	327	333	PF00069	0.660
MOD_PKA_2	418	424	PF00069	0.534
MOD_PKA_2	5	11	PF00069	0.603
MOD_PKA_2	699	705	PF00069	0.559
MOD_PKA_2	804	810	PF00069	0.731
MOD_PKB_1	344	352	PF00069	0.668
MOD_Plk_1	172	178	PF00069	0.661
MOD_Plk_1	266	272	PF00069	0.687
MOD_Plk_1	648	654	PF00069	0.546
MOD_Plk_1	999	1005	PF00069	0.725
MOD_Plk_2-3	173	179	PF00069	0.583
MOD_Plk_2-3	608	614	PF00069	0.592
MOD_Plk_2-3	995	1001	PF00069	0.738
MOD_Plk_4	1024	1030	PF00069	0.641
MOD_Plk_4	1045	1051	PF00069	0.752
MOD_Plk_4	122	128	PF00069	0.725
MOD_Plk_4	355	361	PF00069	0.680
MOD_Plk_4	391	397	PF00069	0.713
MOD_Plk_4	400	406	PF00069	0.536
MOD_Plk_4	76	82	PF00069	0.615
MOD_Plk_4	814	820	PF00069	0.704
MOD_Plk_4	885	891	PF00069	0.725
MOD_Plk_4	942	948	PF00069	0.688
MOD_ProDKin_1	1012	1018	PF00069	0.791
MOD_ProDKin_1	381	387	PF00069	0.777
MOD_ProDKin_1	425	431	PF00069	0.671
MOD_ProDKin_1	490	496	PF00069	0.647
MOD_ProDKin_1	552	558	PF00069	0.676
MOD_ProDKin_1	7	13	PF00069	0.547
MOD_ProDKin_1	811	817	PF00069	0.790
MOD_ProDKin_1	946	952	PF00069	0.665
MOD_ProDKin_1	965	971	PF00069	0.392
MOD_SUMO_rev_2	40	49	PF00179	0.682
TRG_DiLeu_BaEn_1	203	208	PF01217	0.641
TRG_DiLeu_BaEn_2	760	766	PF01217	0.604
TRG_DiLeu_BaLyEn_6	28	33	PF01217	0.621
TRG_DiLeu_BaLyEn_6	405	410	PF01217	0.676
TRG_DiLeu_BaLyEn_6	908	913	PF01217	0.556
TRG_DiLeu_LyEn_5	203	208	PF01217	0.641
TRG_ENDOCYTIC_2	1035	1038	PF00928	0.603
TRG_ENDOCYTIC_2	18	21	PF00928	0.509
TRG_ENDOCYTIC_2	193	196	PF00928	0.706
TRG_ENDOCYTIC_2	205	208	PF00928	0.514
TRG_ENDOCYTIC_2	292	295	PF00928	0.701
TRG_ENDOCYTIC_2	297	300	PF00928	0.638
TRG_ENDOCYTIC_2	763	766	PF00928	0.693
TRG_ENDOCYTIC_2	985	988	PF00928	0.571
TRG_ER_diArg_1	13	16	PF00400	0.583
TRG_ER_diArg_1	312	314	PF00400	0.702
TRG_ER_diArg_1	321	324	PF00400	0.538
TRG_ER_diArg_1	507	510	PF00400	0.676
TRG_ER_diArg_1	694	697	PF00400	0.674
TRG_ER_diArg_1	91	93	PF00400	0.678
TRG_NES_CRM1_1	614	629	PF08389	0.467
TRG_NLS_MonoExtN_4	11	17	PF00514	0.535
TRG_Pf-PMV_PEXEL_1	242	246	PF00026	0.614
TRG_Pf-PMV_PEXEL_1	911	916	PF00026	0.661
TRG_Pf-PMV_PEXEL_1	997	1001	PF00026	0.738

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKX0	Leptomonas seymouri	35%	99%
A0A3S7WYX4	Leishmania donovani	92%	100%
A4HDZ9	Leishmania braziliensis	72%	100%
A4I1B0	Leishmania infantum	92%	100%
E9AXE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%