Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QA16_LEIMA

TriTrypDb:

LmjF.25.0780 , LMJLV39_250014000 , LMJSD75_250013900

Length:

307

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

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Expansion

Sequence features

Q4QA16

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA16

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	299	303	PF00656	0.664
CLV_NRD_NRD_1	214	216	PF00675	0.535
CLV_NRD_NRD_1	57	59	PF00675	0.632
CLV_NRD_NRD_1	93	95	PF00675	0.644
CLV_PCSK_FUR_1	209	213	PF00082	0.480
CLV_PCSK_KEX2_1	211	213	PF00082	0.524
CLV_PCSK_KEX2_1	214	216	PF00082	0.517
CLV_PCSK_KEX2_1	93	95	PF00082	0.644
CLV_PCSK_PC1ET2_1	211	213	PF00082	0.491
CLV_PCSK_SKI1_1	142	146	PF00082	0.589

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IN96	Leishmania donovani	91%	100%
A4HE13	Leishmania braziliensis	57%	90%
A4I1C0	Leishmania infantum	92%	100%
E9AXF6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%

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