LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QA10_LEIMA
TriTrypDb:
LmjF.25.0840 , LMJLV39_250014700 , LMJSD75_250014600 *
Length:
378

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QA10
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA10

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 105 109 PF00656 0.457
CLV_NRD_NRD_1 123 125 PF00675 0.545
CLV_NRD_NRD_1 178 180 PF00675 0.665
CLV_NRD_NRD_1 210 212 PF00675 0.590
CLV_NRD_NRD_1 222 224 PF00675 0.621
CLV_NRD_NRD_1 258 260 PF00675 0.598
CLV_NRD_NRD_1 283 285 PF00675 0.566
CLV_NRD_NRD_1 359 361 PF00675 0.750
CLV_NRD_NRD_1 9 11 PF00675 0.553
CLV_PCSK_KEX2_1 125 127 PF00082 0.466
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1ILI8 Leptomonas seymouri 52% 92%
A0A1X0P4C2 Trypanosomatidae 29% 100%
A0A3S7WYY8 Leishmania donovani 84% 100%
A0A422MPP3 Trypanosoma rangeli 31% 100%
A4HE19 Leishmania braziliensis 64% 90%
A4I1C6 Leishmania infantum 84% 100%
E9AXG2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
V5BXG5 Trypanosoma cruzi 31% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS