Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QA04_LEIMA

TriTrypDb:

LmjF.25.0900 , LMJLV39_250015300 , LMJSD75_250015200

Length:

340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

Q4QA04

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QA04

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	137	139	PF00675	0.802
CLV_NRD_NRD_1	171	173	PF00675	0.789
CLV_NRD_NRD_1	252	254	PF00675	0.346
CLV_NRD_NRD_1	35	37	PF00675	0.578
CLV_PCSK_KEX2_1	170	172	PF00082	0.791
CLV_PCSK_KEX2_1	252	254	PF00082	0.346
CLV_PCSK_KEX2_1	35	37	PF00082	0.619
CLV_PCSK_KEX2_1	45	47	PF00082	0.645
CLV_PCSK_PC1ET2_1	170	172	PF00082	0.659
CLV_PCSK_PC1ET2_1	45	47	PF00082	0.680

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE40	Leptomonas seymouri	40%	100%
A0A3Q8ICA7	Leishmania donovani	89%	100%
A4HE25	Leishmania braziliensis	57%	100%
A4I1D1	Leishmania infantum	89%	100%
E9AXG8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%

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