LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q9W6_LEIMA
TriTrypDb:
LmjF.25.1270 , LMJLV39_250019600 , LMJSD75_250019400
Length:
510

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 2
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

Q4Q9W6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9W6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 114 118 PF00656 0.537
CLV_C14_Caspase3-7 179 183 PF00656 0.523
CLV_NRD_NRD_1 135 137 PF00675 0.743
CLV_NRD_NRD_1 184 186 PF00675 0.636
CLV_NRD_NRD_1 195 197 PF00675 0.563
CLV_NRD_NRD_1 253 255 PF00675 0.539
CLV_NRD_NRD_1 388 390 PF00675 0.456
CLV_NRD_NRD_1 62 64 PF00675 0.514
CLV_NRD_NRD_1 99 101 PF00675 0.532
CLV_PCSK_KEX2_1 135 137 PF00082 0.743
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PC05 Leptomonas seymouri 46% 94%
A0A1X0NLY0 Trypanosomatidae 26% 100%
A0A3R7NU60 Trypanosoma rangeli 28% 100%
A0A3S7WZ41 Leishmania donovani 92% 100%
A4HE69 Leishmania braziliensis 67% 100%
A4I1H1 Leishmania infantum 92% 100%
E9AXK5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS