BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9T2_LEIMA

TriTrypDb:

LmjF.25.1590 , LMJLV39_250023300 , LMJSD75_250023300

Length:

1166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9T2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9T2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	495	499	PF00656	0.631
CLV_C14_Caspase3-7	764	768	PF00656	0.657
CLV_NRD_NRD_1	119	121	PF00675	0.679
CLV_NRD_NRD_1	143	145	PF00675	0.625
CLV_NRD_NRD_1	279	281	PF00675	0.724
CLV_NRD_NRD_1	380	382	PF00675	0.646
CLV_NRD_NRD_1	523	525	PF00675	0.693
CLV_NRD_NRD_1	558	560	PF00675	0.576
CLV_NRD_NRD_1	593	595	PF00675	0.538
CLV_NRD_NRD_1	672	674	PF00675	0.630

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8K3	Leptomonas seymouri	36%	100%
A0A3Q8INI9	Leishmania donovani	86%	100%
A4HEI5	Leishmania braziliensis	61%	94%
A4I1K5	Leishmania infantum	86%	100%
E9AXN9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%

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