LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q9S9_LEIMA
TriTrypDb:
LmjF.25.1620 , LMJLV39_250023600 , LMJSD75_250023600
Length:
145

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9S9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9S9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 91 93 PF00675 0.464
CLV_PCSK_FUR_1 8 12 PF00082 0.634
CLV_PCSK_KEX2_1 10 12 PF00082 0.631
CLV_PCSK_PC1ET2_1 10 12 PF00082 0.631
CLV_PCSK_SKI1_1 103 107 PF00082 0.430
DEG_MDM2_SWIB_1 33 41 PF02201 0.459
DOC_ANK_TNKS_1 10 17 PF00023 0.523
DOC_CYCLIN_yCln2_LP_2 18 24 PF00134 0.497
DOC_WW_Pin1_4 92 97 PF00397 0.530
LIG_14-3-3_CanoR_1 103 112 PF00244 0.437
LIG_APCC_ABBA_1 102 107 PF00400 0.506
LIG_APCC_ABBAyCdc20_2 101 107 PF00400 0.515
LIG_BRCT_BRCA1_1 24 28 PF00533 0.529
LIG_FHA_2 104 110 PF00498 0.446
LIG_LIR_Nem_3 109 115 PF02991 0.436
LIG_LIR_Nem_3 25 31 PF02991 0.490
LIG_Pex14_2 33 37 PF04695 0.473
LIG_SH2_GRB2like 65 68 PF00017 0.561
LIG_SH2_STAT3 31 34 PF00017 0.461
LIG_SH2_STAT5 32 35 PF00017 0.440
LIG_SH2_STAT5 60 63 PF00017 0.434
LIG_SH3_5 130 134 PF00018 0.596
LIG_TRAF2_1 87 90 PF00917 0.535
MOD_CK2_1 103 109 PF00069 0.423
MOD_CK2_1 84 90 PF00069 0.530
MOD_GlcNHglycan 112 115 PF01048 0.437
MOD_GlcNHglycan 137 140 PF01048 0.656
MOD_GlcNHglycan 37 40 PF01048 0.449
MOD_GSK3_1 2 9 PF00069 0.519
MOD_NEK2_1 3 8 PF00069 0.536
MOD_PKB_1 101 109 PF00069 0.453
MOD_Plk_1 67 73 PF00069 0.515
MOD_ProDKin_1 92 98 PF00069 0.528
TRG_DiLeu_BaEn_4 89 95 PF01217 0.520
TRG_ER_diArg_1 100 103 PF00400 0.490
TRG_Pf-PMV_PEXEL_1 92 97 PF00026 0.532

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P8J8 Leptomonas seymouri 77% 100%
A0A0S4IKV2 Bodo saltans 48% 100%
A0A1X0NY74 Trypanosomatidae 65% 100%
A0A3Q8IDC5 Leishmania donovani 99% 100%
A0A422NL14 Trypanosoma rangeli 63% 100%
A4HEI2 Leishmania braziliensis 87% 100%
A4I1K8 Leishmania infantum 99% 100%
C9ZK50 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 68% 100%
E9AXP2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS