PORR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9R6_LEIMA

TriTrypDb:

LmjF.25.1730 , LMJLV39_250024800 , LMJSD75_250024800

Length:

321

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9R6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9R6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	137	139	PF00675	0.410
CLV_NRD_NRD_1	27	29	PF00675	0.482
CLV_NRD_NRD_1	306	308	PF00675	0.356
CLV_NRD_NRD_1	318	320	PF00675	0.505
CLV_NRD_NRD_1	60	62	PF00675	0.617
CLV_PCSK_KEX2_1	167	169	PF00082	0.535
CLV_PCSK_KEX2_1	27	29	PF00082	0.482
CLV_PCSK_KEX2_1	306	308	PF00082	0.356
CLV_PCSK_KEX2_1	60	62	PF00082	0.617
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.535
CLV_PCSK_PC7_1	163	169	PF00082	0.482
CLV_PCSK_SKI1_1	12	16	PF00082	0.584
CLV_PCSK_SKI1_1	138	142	PF00082	0.567
CLV_PCSK_SKI1_1	266	270	PF00082	0.461
CLV_PCSK_SKI1_1	27	31	PF00082	0.716
CLV_PCSK_SKI1_1	306	310	PF00082	0.454
DEG_APCC_DBOX_1	144	152	PF00400	0.441
DEG_SPOP_SBC_1	83	87	PF00917	0.768
DOC_CKS1_1	70	75	PF01111	0.533
DOC_USP7_MATH_1	169	173	PF00917	0.708
DOC_USP7_MATH_1	258	262	PF00917	0.404
DOC_USP7_MATH_1	83	87	PF00917	0.602
DOC_USP7_MATH_1	91	95	PF00917	0.596
DOC_WW_Pin1_4	131	136	PF00397	0.406
DOC_WW_Pin1_4	222	227	PF00397	0.690
DOC_WW_Pin1_4	51	56	PF00397	0.582
DOC_WW_Pin1_4	63	68	PF00397	0.668
DOC_WW_Pin1_4	69	74	PF00397	0.499
DOC_WW_Pin1_4	85	90	PF00397	0.702
LIG_14-3-3_CanoR_1	168	177	PF00244	0.506
LIG_14-3-3_CanoR_1	298	304	PF00244	0.476
LIG_14-3-3_CanoR_1	306	312	PF00244	0.358
LIG_14-3-3_CanoR_1	84	89	PF00244	0.517
LIG_CtBP_PxDLS_1	73	77	PF00389	0.537
LIG_deltaCOP1_diTrp_1	255	259	PF00928	0.367
LIG_FHA_1	172	178	PF00498	0.586
LIG_FHA_1	194	200	PF00498	0.508
LIG_FHA_1	236	242	PF00498	0.604
LIG_FHA_1	46	52	PF00498	0.638
LIG_FHA_2	238	244	PF00498	0.531
LIG_IRF3_LxIS_1	259	265	PF10401	0.478
LIG_LIR_Apic_2	203	208	PF02991	0.492
LIG_LIR_Apic_2	49	55	PF02991	0.639
LIG_LIR_Gen_1	255	264	PF02991	0.383
LIG_LIR_Gen_1	33	44	PF02991	0.651
LIG_LIR_Nem_3	128	133	PF02991	0.428
LIG_LIR_Nem_3	255	259	PF02991	0.367
LIG_LIR_Nem_3	33	39	PF02991	0.645
LIG_LYPXL_yS_3	275	278	PF13949	0.522
LIG_MAD2	139	147	PF02301	0.504
LIG_MYND_1	107	111	PF01753	0.495
LIG_MYND_3	199	203	PF01753	0.475
LIG_PCNA_PIPBox_1	123	132	PF02747	0.308
LIG_Pex14_2	155	159	PF04695	0.356
LIG_REV1ctd_RIR_1	288	298	PF16727	0.489
LIG_SH3_3	174	180	PF00018	0.485
LIG_SH3_3	211	217	PF00018	0.546
LIG_SH3_3	274	280	PF00018	0.354
LIG_SH3_3	64	70	PF00018	0.568
LIG_SUMO_SIM_par_1	110	115	PF11976	0.475
LIG_SUMO_SIM_par_1	72	78	PF11976	0.512
LIG_TRAF2_1	147	150	PF00917	0.485
MOD_CDK_SPxxK_3	131	138	PF00069	0.376
MOD_CDK_SPxxK_3	85	92	PF00069	0.578
MOD_CK1_1	134	140	PF00069	0.399
MOD_CK1_1	42	48	PF00069	0.606
MOD_CK1_1	77	83	PF00069	0.687
MOD_CK1_1	85	91	PF00069	0.530
MOD_CK1_1	94	100	PF00069	0.588
MOD_CK2_1	237	243	PF00069	0.567
MOD_CK2_1	72	78	PF00069	0.795
MOD_DYRK1A_RPxSP_1	131	135	PF00069	0.404
MOD_GlcNHglycan	171	174	PF01048	0.640
MOD_GlcNHglycan	231	234	PF01048	0.594
MOD_GlcNHglycan	42	45	PF01048	0.668
MOD_GlcNHglycan	99	102	PF01048	0.617
MOD_GSK3_1	167	174	PF00069	0.543
MOD_GSK3_1	258	265	PF00069	0.492
MOD_GSK3_1	30	37	PF00069	0.622
MOD_GSK3_1	38	45	PF00069	0.584
MOD_GSK3_1	47	54	PF00069	0.625
MOD_GSK3_1	65	72	PF00069	0.750
MOD_GSK3_1	74	81	PF00069	0.615
MOD_GSK3_1	91	98	PF00069	0.574
MOD_N-GLC_1	235	240	PF02516	0.567
MOD_N-GLC_1	262	267	PF02516	0.517
MOD_NEK2_1	30	35	PF00069	0.696
MOD_NEK2_1	38	43	PF00069	0.531
MOD_PIKK_1	167	173	PF00454	0.520
MOD_PK_1	92	98	PF00069	0.583
MOD_PKA_1	167	173	PF00069	0.520
MOD_PKA_2	167	173	PF00069	0.520
MOD_PKA_2	39	45	PF00069	0.546
MOD_PKA_2	83	89	PF00069	0.622
MOD_PKA_2	91	97	PF00069	0.616
MOD_Plk_1	236	242	PF00069	0.549
MOD_Plk_1	92	98	PF00069	0.583
MOD_Plk_4	115	121	PF00069	0.513
MOD_Plk_4	299	305	PF00069	0.458
MOD_Plk_4	47	53	PF00069	0.748
MOD_ProDKin_1	131	137	PF00069	0.399
MOD_ProDKin_1	222	228	PF00069	0.692
MOD_ProDKin_1	51	57	PF00069	0.582
MOD_ProDKin_1	63	69	PF00069	0.668
MOD_ProDKin_1	85	91	PF00069	0.701
MOD_SUMO_rev_2	261	270	PF00179	0.499
TRG_DiLeu_BaEn_1	115	120	PF01217	0.494
TRG_DiLeu_BaLyEn_6	52	57	PF01217	0.609
TRG_ENDOCYTIC_2	275	278	PF00928	0.562
TRG_ENDOCYTIC_2	287	290	PF00928	0.308
TRG_ER_diArg_1	26	28	PF00400	0.742
TRG_ER_diArg_1	305	307	PF00400	0.355
TRG_NES_CRM1_1	115	128	PF08389	0.407
TRG_Pf-PMV_PEXEL_1	307	312	PF00026	0.402

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMC8	Leptomonas seymouri	53%	99%
A0A3S7WZA0	Leishmania donovani	90%	100%
A0A422NGK2	Trypanosoma rangeli	32%	100%
A4HEG9	Leishmania braziliensis	67%	100%
A4I1M1	Leishmania infantum	91%	100%
C9ZK64	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	98%
E9AXQ5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
V5BHV8	Trypanosoma cruzi	32%	100%