Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9Q9_LEIMA

TriTrypDb:

LmjF.25.1800 , LMJLV39_250025500 , LMJSD75_250025500

Length:

1031

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9Q9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9Q9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.675
CLV_C14_Caspase3-7	30	34	PF00656	0.747
CLV_C14_Caspase3-7	300	304	PF00656	0.659
CLV_NRD_NRD_1	327	329	PF00675	0.526
CLV_NRD_NRD_1	546	548	PF00675	0.523
CLV_NRD_NRD_1	572	574	PF00675	0.637
CLV_NRD_NRD_1	600	602	PF00675	0.594
CLV_NRD_NRD_1	696	698	PF00675	0.418
CLV_NRD_NRD_1	730	732	PF00675	0.634
CLV_NRD_NRD_1	795	797	PF00675	0.437
CLV_NRD_NRD_1	896	898	PF00675	0.481
CLV_NRD_NRD_1	956	958	PF00675	0.631
CLV_PCSK_FUR_1	728	732	PF00082	0.633
CLV_PCSK_KEX2_1	327	329	PF00082	0.526
CLV_PCSK_KEX2_1	545	547	PF00082	0.526
CLV_PCSK_KEX2_1	572	574	PF00082	0.637
CLV_PCSK_KEX2_1	600	602	PF00082	0.594
CLV_PCSK_KEX2_1	696	698	PF00082	0.418
CLV_PCSK_KEX2_1	730	732	PF00082	0.634
CLV_PCSK_KEX2_1	794	796	PF00082	0.439
CLV_PCSK_KEX2_1	896	898	PF00082	0.481
CLV_PCSK_PC7_1	596	602	PF00082	0.622
CLV_PCSK_SKI1_1	327	331	PF00082	0.510
CLV_PCSK_SKI1_1	547	551	PF00082	0.540
CLV_PCSK_SKI1_1	678	682	PF00082	0.492
CLV_PCSK_SKI1_1	697	701	PF00082	0.424
CLV_PCSK_SKI1_1	855	859	PF00082	0.523
DEG_APCC_DBOX_1	326	334	PF00400	0.767
DEG_APCC_DBOX_1	794	802	PF00400	0.685
DEG_APCC_DBOX_1	827	835	PF00400	0.624
DEG_Nend_Nbox_1	1	3	PF02207	0.705
DEG_SPOP_SBC_1	118	122	PF00917	0.821
DEG_SPOP_SBC_1	290	294	PF00917	0.663
DEG_SPOP_SBC_1	475	479	PF00917	0.705
DEG_SPOP_SBC_1	485	489	PF00917	0.700
DEG_SPOP_SBC_1	578	582	PF00917	0.823
DOC_CDC14_PxL_1	44	52	PF14671	0.771
DOC_CKS1_1	565	570	PF01111	0.799
DOC_CKS1_1	702	707	PF01111	0.722
DOC_CYCLIN_RxL_1	678	689	PF00134	0.604
DOC_CYCLIN_yCln2_LP_2	565	571	PF00134	0.772
DOC_MAPK_gen_1	545	557	PF00069	0.733
DOC_MAPK_gen_1	600	606	PF00069	0.768
DOC_MAPK_gen_1	725	734	PF00069	0.398
DOC_MAPK_gen_1	896	904	PF00069	0.639
DOC_MAPK_gen_1	985	995	PF00069	0.753
DOC_MAPK_MEF2A_6	390	399	PF00069	0.693
DOC_MAPK_MEF2A_6	550	557	PF00069	0.730
DOC_PP1_RVXF_1	326	333	PF00149	0.693
DOC_PP1_RVXF_1	823	830	PF00149	0.679
DOC_PP1_RVXF_1	89	96	PF00149	0.721
DOC_PP2B_LxvP_1	402	405	PF13499	0.714
DOC_PP2B_LxvP_1	683	686	PF13499	0.612
DOC_PP2B_LxvP_1	743	746	PF13499	0.411
DOC_PP4_FxxP_1	40	43	PF00568	0.812
DOC_USP7_MATH_1	119	123	PF00917	0.787
DOC_USP7_MATH_1	151	155	PF00917	0.797
DOC_USP7_MATH_1	174	178	PF00917	0.771
DOC_USP7_MATH_1	290	294	PF00917	0.749
DOC_USP7_MATH_1	411	415	PF00917	0.670
DOC_USP7_MATH_1	451	455	PF00917	0.744
DOC_USP7_MATH_1	463	467	PF00917	0.778
DOC_USP7_MATH_1	475	479	PF00917	0.708
DOC_USP7_MATH_1	486	490	PF00917	0.784
DOC_USP7_MATH_1	49	53	PF00917	0.729
DOC_USP7_MATH_1	536	540	PF00917	0.745
DOC_USP7_MATH_1	548	552	PF00917	0.761
DOC_USP7_MATH_1	639	643	PF00917	0.730
DOC_USP7_MATH_1	686	690	PF00917	0.578
DOC_USP7_MATH_1	739	743	PF00917	0.411
DOC_USP7_MATH_1	777	781	PF00917	0.714
DOC_USP7_MATH_1	920	924	PF00917	0.815
DOC_USP7_MATH_1	944	948	PF00917	0.749
DOC_USP7_MATH_1	966	970	PF00917	0.785
DOC_USP7_MATH_2	92	98	PF00917	0.751
DOC_WW_Pin1_4	169	174	PF00397	0.738
DOC_WW_Pin1_4	182	187	PF00397	0.837
DOC_WW_Pin1_4	267	272	PF00397	0.822
DOC_WW_Pin1_4	291	296	PF00397	0.724
DOC_WW_Pin1_4	311	316	PF00397	0.769
DOC_WW_Pin1_4	345	350	PF00397	0.750
DOC_WW_Pin1_4	564	569	PF00397	0.804
DOC_WW_Pin1_4	701	706	PF00397	0.659
DOC_WW_Pin1_4	786	791	PF00397	0.609
DOC_WW_Pin1_4	980	985	PF00397	0.743
LIG_14-3-3_CanoR_1	390	399	PF00244	0.764
LIG_14-3-3_CanoR_1	547	553	PF00244	0.756
LIG_14-3-3_CanoR_1	55	61	PF00244	0.749
LIG_14-3-3_CanoR_1	828	832	PF00244	0.594
LIG_14-3-3_CanoR_1	848	856	PF00244	0.546
LIG_14-3-3_CanoR_1	914	922	PF00244	0.705
LIG_14-3-3_CanoR_1	939	948	PF00244	0.779
LIG_Actin_WH2_2	318	333	PF00022	0.780
LIG_Actin_WH2_2	900	916	PF00022	0.609
LIG_BIR_III_4	615	619	PF00653	0.766
LIG_BRCT_BRCA1_1	292	296	PF00533	0.753
LIG_FHA_1	187	193	PF00498	0.756
LIG_FHA_1	196	202	PF00498	0.706
LIG_FHA_1	312	318	PF00498	0.759
LIG_FHA_1	358	364	PF00498	0.769
LIG_FHA_1	505	511	PF00498	0.761
LIG_FHA_1	60	66	PF00498	0.769
LIG_FHA_1	705	711	PF00498	0.345
LIG_FHA_1	721	727	PF00498	0.392
LIG_FHA_1	80	86	PF00498	0.649
LIG_FHA_1	806	812	PF00498	0.663
LIG_FHA_1	943	949	PF00498	0.671
LIG_FHA_2	984	990	PF00498	0.742
LIG_HCF-1_HBM_1	368	371	PF13415	0.767
LIG_LIR_Apic_2	1010	1016	PF02991	0.631
LIG_LIR_Apic_2	39	43	PF02991	0.758
LIG_LIR_Apic_2	642	646	PF02991	0.683
LIG_LIR_Gen_1	384	391	PF02991	0.683
LIG_LIR_Gen_1	551	558	PF02991	0.748
LIG_LIR_LC3C_4	990	995	PF02991	0.627
LIG_LIR_Nem_3	221	227	PF02991	0.732
LIG_LIR_Nem_3	378	382	PF02991	0.707
LIG_LIR_Nem_3	384	388	PF02991	0.656
LIG_LIR_Nem_3	551	555	PF02991	0.749
LIG_LYPXL_yS_3	209	212	PF13949	0.616
LIG_LYPXL_yS_3	379	382	PF13949	0.756
LIG_LYPXL_yS_3	47	50	PF13949	0.768
LIG_MAD2	725	733	PF02301	0.375
LIG_Pex14_2	381	385	PF04695	0.676
LIG_Pex14_2	40	44	PF04695	0.742
LIG_SH2_CRK	68	72	PF00017	0.780
LIG_SH2_PTP2	643	646	PF00017	0.722
LIG_SH2_PTP2	711	714	PF00017	0.436
LIG_SH2_STAT5	643	646	PF00017	0.722
LIG_SH2_STAT5	711	714	PF00017	0.411
LIG_SH3_2	595	600	PF14604	0.685
LIG_SH3_3	167	173	PF00018	0.708
LIG_SH3_3	200	206	PF00018	0.754
LIG_SH3_3	207	213	PF00018	0.705
LIG_SH3_3	443	449	PF00018	0.779
LIG_SH3_3	507	513	PF00018	0.760
LIG_SH3_3	537	543	PF00018	0.777
LIG_SH3_3	552	558	PF00018	0.667
LIG_SH3_3	592	598	PF00018	0.695
LIG_SH3_3	699	705	PF00018	0.687
LIG_SH3_3	712	718	PF00018	0.295
LIG_SH3_3	72	78	PF00018	0.759
LIG_SH3_3	880	886	PF00018	0.713
LIG_SH3_3	895	901	PF00018	0.626
LIG_SUMO_SIM_anti_2	561	567	PF11976	0.752
LIG_SUMO_SIM_anti_2	800	806	PF11976	0.594
LIG_SUMO_SIM_par_1	192	198	PF11976	0.727
LIG_SUMO_SIM_par_1	800	806	PF11976	0.568
LIG_TYR_ITIM	709	714	PF00017	0.436
LIG_UBA3_1	691	700	PF00899	0.600
LIG_WRC_WIRS_1	804	809	PF05994	0.662
MOD_CDK_SPK_2	980	985	PF00069	0.743
MOD_CK1_1	122	128	PF00069	0.801
MOD_CK1_1	172	178	PF00069	0.775
MOD_CK1_1	231	237	PF00069	0.761
MOD_CK1_1	251	257	PF00069	0.846
MOD_CK1_1	347	353	PF00069	0.753
MOD_CK1_1	357	363	PF00069	0.788
MOD_CK1_1	414	420	PF00069	0.646
MOD_CK1_1	477	483	PF00069	0.750
MOD_CK1_1	506	512	PF00069	0.837
MOD_CK1_1	57	63	PF00069	0.800
MOD_CK1_1	579	585	PF00069	0.820
MOD_CK1_1	629	635	PF00069	0.803
MOD_CK1_1	662	668	PF00069	0.678
MOD_CK1_1	867	873	PF00069	0.785
MOD_CK1_1	942	948	PF00069	0.711
MOD_CK1_1	969	975	PF00069	0.772
MOD_CK2_1	274	280	PF00069	0.684
MOD_CK2_1	390	396	PF00069	0.677
MOD_CK2_1	5	11	PF00069	0.652
MOD_CK2_1	629	635	PF00069	0.742
MOD_CK2_1	803	809	PF00069	0.594
MOD_CK2_1	887	893	PF00069	0.773
MOD_CK2_1	972	978	PF00069	0.784
MOD_CK2_1	983	989	PF00069	0.650
MOD_Cter_Amidation	325	328	PF01082	0.559
MOD_GlcNHglycan	132	135	PF01048	0.543
MOD_GlcNHglycan	143	146	PF01048	0.560
MOD_GlcNHglycan	159	162	PF01048	0.562
MOD_GlcNHglycan	165	168	PF01048	0.547
MOD_GlcNHglycan	177	180	PF01048	0.429
MOD_GlcNHglycan	250	253	PF01048	0.599
MOD_GlcNHglycan	276	279	PF01048	0.550
MOD_GlcNHglycan	357	360	PF01048	0.583
MOD_GlcNHglycan	392	395	PF01048	0.436
MOD_GlcNHglycan	413	416	PF01048	0.587
MOD_GlcNHglycan	428	431	PF01048	0.508
MOD_GlcNHglycan	446	449	PF01048	0.366
MOD_GlcNHglycan	457	460	PF01048	0.574
MOD_GlcNHglycan	479	482	PF01048	0.540
MOD_GlcNHglycan	488	491	PF01048	0.516
MOD_GlcNHglycan	526	529	PF01048	0.563
MOD_GlcNHglycan	664	667	PF01048	0.522
MOD_GlcNHglycan	7	10	PF01048	0.445
MOD_GlcNHglycan	753	756	PF01048	0.518
MOD_GlcNHglycan	765	768	PF01048	0.451
MOD_GlcNHglycan	849	852	PF01048	0.523
MOD_GlcNHglycan	890	893	PF01048	0.566
MOD_GlcNHglycan	922	925	PF01048	0.612
MOD_GlcNHglycan	926	929	PF01048	0.570
MOD_GlcNHglycan	968	971	PF01048	0.552
MOD_GlcNHglycan	974	977	PF01048	0.563
MOD_GSK3_1	114	121	PF00069	0.784
MOD_GSK3_1	147	154	PF00069	0.814
MOD_GSK3_1	182	189	PF00069	0.716
MOD_GSK3_1	231	238	PF00069	0.793
MOD_GSK3_1	243	250	PF00069	0.777
MOD_GSK3_1	261	268	PF00069	0.607
MOD_GSK3_1	27	34	PF00069	0.745
MOD_GSK3_1	309	316	PF00069	0.792
MOD_GSK3_1	340	347	PF00069	0.790
MOD_GSK3_1	350	357	PF00069	0.747
MOD_GSK3_1	422	429	PF00069	0.783
MOD_GSK3_1	451	458	PF00069	0.728
MOD_GSK3_1	476	483	PF00069	0.733
MOD_GSK3_1	484	491	PF00069	0.749
MOD_GSK3_1	49	56	PF00069	0.756
MOD_GSK3_1	500	507	PF00069	0.794
MOD_GSK3_1	578	585	PF00069	0.776
MOD_GSK3_1	665	672	PF00069	0.699
MOD_GSK3_1	855	862	PF00069	0.784
MOD_GSK3_1	920	927	PF00069	0.786
MOD_GSK3_1	966	973	PF00069	0.734
MOD_LATS_1	241	247	PF00433	0.842
MOD_N-GLC_1	130	135	PF02516	0.469
MOD_N-GLC_1	151	156	PF02516	0.599
MOD_N-GLC_1	375	380	PF02516	0.434
MOD_N-GLC_1	523	528	PF02516	0.456
MOD_N-GLC_1	669	674	PF02516	0.413
MOD_N-GLC_1	924	929	PF02516	0.458
MOD_NEK2_1	195	200	PF00069	0.713
MOD_NEK2_1	259	264	PF00069	0.839
MOD_NEK2_1	344	349	PF00069	0.777
MOD_NEK2_1	354	359	PF00069	0.762
MOD_NEK2_1	426	431	PF00069	0.756
MOD_NEK2_1	469	474	PF00069	0.758
MOD_NEK2_1	54	59	PF00069	0.779
MOD_NEK2_1	720	725	PF00069	0.445
MOD_NEK2_1	87	92	PF00069	0.787
MOD_NEK2_1	887	892	PF00069	0.723
MOD_NEK2_1	913	918	PF00069	0.694
MOD_NEK2_2	669	674	PF00069	0.616
MOD_PIKK_1	54	60	PF00454	0.774
MOD_PIKK_1	629	635	PF00454	0.730
MOD_PIKK_1	788	794	PF00454	0.692
MOD_PIKK_1	94	100	PF00454	0.815
MOD_PK_1	208	214	PF00069	0.616
MOD_PKA_2	54	60	PF00069	0.750
MOD_PKA_2	827	833	PF00069	0.644
MOD_PKA_2	847	853	PF00069	0.548
MOD_PKA_2	913	919	PF00069	0.685
MOD_PKA_2	949	955	PF00069	0.755
MOD_PKB_1	77	85	PF00069	0.738
MOD_Plk_1	220	226	PF00069	0.726
MOD_Plk_1	375	381	PF00069	0.723
MOD_Plk_1	669	675	PF00069	0.674
MOD_Plk_2-3	31	37	PF00069	0.749
MOD_Plk_2-3	803	809	PF00069	0.594
MOD_Plk_4	1008	1014	PF00069	0.622
MOD_Plk_4	340	346	PF00069	0.752
MOD_Plk_4	347	353	PF00069	0.632
MOD_Plk_4	536	542	PF00069	0.764
MOD_Plk_4	548	554	PF00069	0.759
MOD_Plk_4	623	629	PF00069	0.729
MOD_Plk_4	639	645	PF00069	0.580
MOD_Plk_4	649	655	PF00069	0.653
MOD_Plk_4	659	665	PF00069	0.449
MOD_Plk_4	739	745	PF00069	0.411
MOD_Plk_4	771	777	PF00069	0.739
MOD_Plk_4	816	822	PF00069	0.633
MOD_Plk_4	908	914	PF00069	0.627
MOD_ProDKin_1	169	175	PF00069	0.738
MOD_ProDKin_1	182	188	PF00069	0.836
MOD_ProDKin_1	267	273	PF00069	0.824
MOD_ProDKin_1	291	297	PF00069	0.725
MOD_ProDKin_1	311	317	PF00069	0.770
MOD_ProDKin_1	345	351	PF00069	0.750
MOD_ProDKin_1	564	570	PF00069	0.804
MOD_ProDKin_1	701	707	PF00069	0.654
MOD_ProDKin_1	786	792	PF00069	0.604
MOD_ProDKin_1	980	986	PF00069	0.739
TRG_DiLeu_BaEn_1	989	994	PF01217	0.680
TRG_DiLeu_BaEn_2	35	41	PF01217	0.761
TRG_DiLeu_BaLyEn_6	190	195	PF01217	0.735
TRG_DiLeu_BaLyEn_6	325	330	PF01217	0.672
TRG_DiLeu_BaLyEn_6	830	835	PF01217	0.625
TRG_ENDOCYTIC_2	209	212	PF00928	0.616
TRG_ENDOCYTIC_2	379	382	PF00928	0.756
TRG_ENDOCYTIC_2	47	50	PF00928	0.768
TRG_ENDOCYTIC_2	68	71	PF00928	0.780
TRG_ENDOCYTIC_2	711	714	PF00928	0.436
TRG_ER_diArg_1	253	256	PF00400	0.680
TRG_ER_diArg_1	327	329	PF00400	0.765
TRG_ER_diArg_1	544	547	PF00400	0.740
TRG_ER_diArg_1	572	575	PF00400	0.782
TRG_ER_diArg_1	599	601	PF00400	0.825
TRG_ER_diArg_1	695	697	PF00400	0.609
TRG_ER_diArg_1	727	730	PF00400	0.403
TRG_ER_diArg_1	793	796	PF00400	0.628
TRG_ER_diArg_1	896	898	PF00400	0.681
TRG_ER_diArg_1	938	941	PF00400	0.760
TRG_Pf-PMV_PEXEL_1	331	335	PF00026	0.500
TRG_Pf-PMV_PEXEL_1	607	611	PF00026	0.541
TRG_Pf-PMV_PEXEL_1	796	800	PF00026	0.492
TRG_Pf-PMV_PEXEL_1	985	989	PF00026	0.543
TRG_PTS2	1	20	PF00400	0.705

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8W8	Leptomonas seymouri	42%	100%
A0A3S7WZ87	Leishmania donovani	91%	100%
A4HEJ0	Leishmania braziliensis	65%	100%
A4I1M8	Leishmania infantum	91%	100%
E9AXR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%