Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9M2_LEIMA

TriTrypDb:

LmjF.25.2155

Length:

251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9M2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9M2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	199	201	PF00675	0.599
CLV_PCSK_KEX2_1	213	215	PF00082	0.756
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.756
CLV_PCSK_SKI1_1	170	174	PF00082	0.639
DEG_Nend_UBRbox_2	1	3	PF02207	0.730
DEG_SCF_FBW7_1	227	234	PF00400	0.751
DOC_MAPK_gen_1	151	161	PF00069	0.542
DOC_USP7_MATH_1	146	150	PF00917	0.546
DOC_USP7_MATH_1	222	226	PF00917	0.679
DOC_USP7_MATH_1	231	235	PF00917	0.705
DOC_USP7_MATH_1	86	90	PF00917	0.772
DOC_WW_Pin1_4	227	232	PF00397	0.707
DOC_WW_Pin1_4	36	41	PF00397	0.779
DOC_WW_Pin1_4	78	83	PF00397	0.651
LIG_14-3-3_CanoR_1	103	109	PF00244	0.595
LIG_14-3-3_CanoR_1	59	67	PF00244	0.591
LIG_Actin_WH2_2	4	21	PF00022	0.597
LIG_FHA_1	103	109	PF00498	0.575
LIG_FHA_1	216	222	PF00498	0.738
LIG_FHA_1	237	243	PF00498	0.568
LIG_FHA_1	43	49	PF00498	0.728
LIG_FHA_2	135	141	PF00498	0.577
LIG_FHA_2	8	14	PF00498	0.657
LIG_LIR_Gen_1	130	139	PF02991	0.633
LIG_LIR_Gen_1	182	192	PF02991	0.527
LIG_LIR_Gen_1	99	109	PF02991	0.619
LIG_LIR_Nem_3	130	136	PF02991	0.633
LIG_LIR_Nem_3	182	187	PF02991	0.632
LIG_LIR_Nem_3	243	249	PF02991	0.555
LIG_LIR_Nem_3	99	104	PF02991	0.631
LIG_NRBOX	237	243	PF00104	0.568
LIG_Rb_LxCxE_1	182	202	PF01857	0.578
LIG_SH2_STAP1	176	180	PF00017	0.517
LIG_SH2_STAP1	27	31	PF00017	0.724
MOD_CDK_SPxxK_3	78	85	PF00069	0.800
MOD_CK1_1	134	140	PF00069	0.452
MOD_CK1_1	142	148	PF00069	0.370
MOD_CK1_1	168	174	PF00069	0.633
MOD_CK1_1	175	181	PF00069	0.522
MOD_CK1_1	206	212	PF00069	0.683
MOD_CK1_1	29	35	PF00069	0.783
MOD_CK1_1	58	64	PF00069	0.670
MOD_CK1_1	70	76	PF00069	0.719
MOD_CK1_1	88	94	PF00069	0.709
MOD_CK2_1	134	140	PF00069	0.562
MOD_CK2_1	196	202	PF00069	0.531
MOD_CK2_1	222	228	PF00069	0.515
MOD_CK2_1	7	13	PF00069	0.658
MOD_CK2_1	86	92	PF00069	0.793
MOD_GlcNHglycan	165	170	PF01048	0.547
MOD_GlcNHglycan	177	181	PF01048	0.407
MOD_GSK3_1	104	111	PF00069	0.279
MOD_GSK3_1	142	149	PF00069	0.407
MOD_GSK3_1	168	175	PF00069	0.504
MOD_GSK3_1	179	186	PF00069	0.582
MOD_GSK3_1	227	234	PF00069	0.625
MOD_GSK3_1	32	39	PF00069	0.789
MOD_GSK3_1	54	61	PF00069	0.679
MOD_GSK3_1	84	91	PF00069	0.804
MOD_N-GLC_1	123	128	PF02516	0.371
MOD_N-GLC_1	222	227	PF02516	0.595
MOD_NEK2_1	139	144	PF00069	0.426
MOD_NEK2_1	43	48	PF00069	0.632
MOD_NEK2_2	146	151	PF00069	0.547
MOD_OFUCOSY	100	106	PF10250	0.364
MOD_PIKK_1	29	35	PF00454	0.783
MOD_PIKK_1	72	78	PF00454	0.736
MOD_PIKK_1	86	92	PF00454	0.626
MOD_PKA_2	102	108	PF00069	0.318
MOD_PKA_2	58	64	PF00069	0.722
MOD_PKA_2	84	90	PF00069	0.805
MOD_Plk_1	14	20	PF00069	0.564
MOD_Plk_4	104	110	PF00069	0.525
MOD_Plk_4	191	197	PF00069	0.428
MOD_Plk_4	222	228	PF00069	0.665
MOD_Plk_4	32	38	PF00069	0.682
MOD_ProDKin_1	227	233	PF00069	0.704
MOD_ProDKin_1	36	42	PF00069	0.779
MOD_ProDKin_1	78	84	PF00069	0.655
TRG_DiLeu_BaEn_1	191	196	PF01217	0.612
TRG_DiLeu_BaLyEn_6	148	153	PF01217	0.544
TRG_DiLeu_BaLyEn_6	39	44	PF01217	0.663
TRG_ER_diArg_1	153	156	PF00400	0.384
TRG_Pf-PMV_PEXEL_1	247	251	PF00026	0.586

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYI0	Leptomonas seymouri	32%	100%
A0A3Q8INN7	Leishmania donovani	86%	100%
A4HEB9	Leishmania braziliensis	68%	100%
A4I1R4	Leishmania infantum	85%	100%
E9AXU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%