Glycine cleavage system P protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

pyridoxal phosphate containing glycine decarboxylase, putative

Species:

Leishmania major

UniProt:

Q4Q9I8_LEIMA

TriTrypDb:

LmjF.26.0030 , LMJLV39_260005300 , LMJSD75_260005200

Length:

972

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	11
GO:0005960	glycine cleavage complex	4	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:1902494	catalytic complex	2	2
GO:1990204	oxidoreductase complex	3	2

Expansion

Sequence features

Q4Q9I8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9I8

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	11
GO:0006520	amino acid metabolic process	3	11
GO:0006544	glycine metabolic process	6	11
GO:0006546	glycine catabolic process	5	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009056	catabolic process	2	11
GO:0009063	amino acid catabolic process	4	11
GO:0009069	serine family amino acid metabolic process	5	11
GO:0009071	serine family amino acid catabolic process	6	11
GO:0009987	cellular process	1	11
GO:0016054	organic acid catabolic process	4	11
GO:0019464	glycine decarboxylation via glycine cleavage system	6	2
GO:0019752	carboxylic acid metabolic process	5	11
GO:0043436	oxoacid metabolic process	4	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044248	cellular catabolic process	3	11
GO:0044281	small molecule metabolic process	2	11
GO:0044282	small molecule catabolic process	3	11
GO:0046395	carboxylic acid catabolic process	5	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11
GO:1901565	organonitrogen compound catabolic process	4	11
GO:1901575	organic substance catabolic process	3	11
GO:1901605	alpha-amino acid metabolic process	4	11
GO:1901606	alpha-amino acid catabolic process	5	11

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004375	glycine dehydrogenase (decarboxylating) activity	5	11
GO:0005488	binding	1	2
GO:0016491	oxidoreductase activity	2	11
GO:0016594	glycine binding	4	2
GO:0016597	amino acid binding	4	2
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3	11
GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	4	11
GO:0019842	vitamin binding	3	2
GO:0030170	pyridoxal phosphate binding	4	2
GO:0031406	carboxylic acid binding	4	2
GO:0036094	small molecule binding	2	2
GO:0043167	ion binding	2	2
GO:0043168	anion binding	3	2
GO:0043169	cation binding	3	2
GO:0043177	organic acid binding	3	2
GO:0070279	vitamin B6 binding	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2
GO:0016829	lyase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	21	25	PF00656	0.617
CLV_NRD_NRD_1	180	182	PF00675	0.379
CLV_NRD_NRD_1	3	5	PF00675	0.672
CLV_NRD_NRD_1	34	36	PF00675	0.470
CLV_NRD_NRD_1	481	483	PF00675	0.397
CLV_NRD_NRD_1	509	511	PF00675	0.326
CLV_NRD_NRD_1	677	679	PF00675	0.470
CLV_NRD_NRD_1	892	894	PF00675	0.498
CLV_PCSK_FUR_1	177	181	PF00082	0.437
CLV_PCSK_KEX2_1	179	181	PF00082	0.345
CLV_PCSK_KEX2_1	3	5	PF00082	0.672
CLV_PCSK_KEX2_1	305	307	PF00082	0.326
CLV_PCSK_KEX2_1	337	339	PF00082	0.345
CLV_PCSK_KEX2_1	807	809	PF00082	0.362
CLV_PCSK_KEX2_1	848	850	PF00082	0.352
CLV_PCSK_KEX2_1	878	880	PF00082	0.453
CLV_PCSK_KEX2_1	892	894	PF00082	0.370
CLV_PCSK_PC1ET2_1	179	181	PF00082	0.345
CLV_PCSK_PC1ET2_1	305	307	PF00082	0.326
CLV_PCSK_PC1ET2_1	337	339	PF00082	0.345
CLV_PCSK_PC1ET2_1	807	809	PF00082	0.348
CLV_PCSK_PC1ET2_1	848	850	PF00082	0.352
CLV_PCSK_PC1ET2_1	878	880	PF00082	0.464
CLV_PCSK_SKI1_1	111	115	PF00082	0.398
CLV_PCSK_SKI1_1	181	185	PF00082	0.360
CLV_PCSK_SKI1_1	187	191	PF00082	0.329
CLV_PCSK_SKI1_1	3	7	PF00082	0.617
CLV_PCSK_SKI1_1	326	330	PF00082	0.326
CLV_PCSK_SKI1_1	631	635	PF00082	0.398
CLV_PCSK_SKI1_1	651	655	PF00082	0.442
CLV_PCSK_SKI1_1	678	682	PF00082	0.355
CLV_PCSK_SKI1_1	833	837	PF00082	0.426
CLV_PCSK_SKI1_1	90	94	PF00082	0.401
CLV_PCSK_SKI1_1	918	922	PF00082	0.427
CLV_Separin_Metazoa	500	504	PF03568	0.326
DEG_Nend_Nbox_1	1	3	PF02207	0.637
DEG_SCF_FBW7_1	122	128	PF00400	0.431
DEG_SCF_FBW7_2	458	464	PF00400	0.483
DOC_CKS1_1	119	124	PF01111	0.345
DOC_CKS1_1	228	233	PF01111	0.346
DOC_CKS1_1	284	289	PF01111	0.437
DOC_CKS1_1	458	463	PF01111	0.517
DOC_CKS1_1	63	68	PF01111	0.414
DOC_CYCLIN_yCln2_LP_2	114	120	PF00134	0.437
DOC_MAPK_gen_1	654	664	PF00069	0.369
DOC_PP1_RVXF_1	534	541	PF00149	0.424
DOC_PP1_RVXF_1	606	613	PF00149	0.470
DOC_PP2B_PxIxI_1	322	328	PF00149	0.237
DOC_PP4_FxxP_1	284	287	PF00568	0.326
DOC_PP4_FxxP_1	723	726	PF00568	0.317
DOC_PP4_FxxP_1	855	858	PF00568	0.397
DOC_USP7_MATH_1	125	129	PF00917	0.431
DOC_USP7_MATH_1	521	525	PF00917	0.326
DOC_USP7_MATH_1	576	580	PF00917	0.379
DOC_USP7_MATH_1	872	876	PF00917	0.354
DOC_USP7_MATH_2	872	878	PF00917	0.396
DOC_USP7_UBL2_3	43	47	PF12436	0.424
DOC_WW_Pin1_4	118	123	PF00397	0.385
DOC_WW_Pin1_4	227	232	PF00397	0.354
DOC_WW_Pin1_4	283	288	PF00397	0.437
DOC_WW_Pin1_4	305	310	PF00397	0.424
DOC_WW_Pin1_4	389	394	PF00397	0.409
DOC_WW_Pin1_4	457	462	PF00397	0.525
DOC_WW_Pin1_4	62	67	PF00397	0.414
LIG_14-3-3_CanoR_1	19	27	PF00244	0.588
LIG_14-3-3_CanoR_1	536	541	PF00244	0.424
LIG_14-3-3_CanoR_1	556	562	PF00244	0.140
LIG_14-3-3_CanoR_1	678	684	PF00244	0.470
LIG_Actin_WH2_2	466	484	PF00022	0.506
LIG_APCC_ABBA_1	425	430	PF00400	0.398
LIG_BIR_III_4	232	236	PF00653	0.398
LIG_BRCT_BRCA1_1	223	227	PF00533	0.431
LIG_BRCT_BRCA1_1	387	391	PF00533	0.411
LIG_BRCT_BRCA1_1	488	492	PF00533	0.392
LIG_BRCT_BRCA1_1	758	762	PF00533	0.424
LIG_BRCT_BRCA1_1	778	782	PF00533	0.153
LIG_eIF4E_1	957	963	PF01652	0.420
LIG_FHA_1	299	305	PF00498	0.424
LIG_FHA_1	340	346	PF00498	0.326
LIG_FHA_1	431	437	PF00498	0.324
LIG_FHA_1	458	464	PF00498	0.470
LIG_FHA_1	470	476	PF00498	0.490
LIG_FHA_1	524	530	PF00498	0.326
LIG_FHA_1	53	59	PF00498	0.398
LIG_FHA_1	648	654	PF00498	0.237
LIG_FHA_1	667	673	PF00498	0.313
LIG_FHA_1	679	685	PF00498	0.301
LIG_FHA_1	720	726	PF00498	0.326
LIG_FHA_1	74	80	PF00498	0.437
LIG_FHA_1	836	842	PF00498	0.421
LIG_FHA_1	865	871	PF00498	0.395
LIG_FHA_2	147	153	PF00498	0.346
LIG_FHA_2	19	25	PF00498	0.576
LIG_FHA_2	32	38	PF00498	0.314
LIG_FHA_2	395	401	PF00498	0.359
LIG_FHA_2	410	416	PF00498	0.301
LIG_FHA_2	791	797	PF00498	0.463
LIG_FHA_2	871	877	PF00498	0.379
LIG_FHA_2	919	925	PF00498	0.460
LIG_FHA_2	954	960	PF00498	0.464
LIG_Integrin_RGD_1	900	902	PF01839	0.560
LIG_LIR_Apic_2	722	726	PF02991	0.318
LIG_LIR_Apic_2	852	858	PF02991	0.399
LIG_LIR_Apic_2	923	928	PF02991	0.465
LIG_LIR_Gen_1	239	247	PF02991	0.345
LIG_LIR_Gen_1	396	406	PF02991	0.327
LIG_LIR_Gen_1	542	551	PF02991	0.344
LIG_LIR_Gen_1	777	786	PF02991	0.341
LIG_LIR_Gen_1	795	805	PF02991	0.344
LIG_LIR_Nem_3	121	126	PF02991	0.345
LIG_LIR_Nem_3	167	173	PF02991	0.345
LIG_LIR_Nem_3	239	243	PF02991	0.345
LIG_LIR_Nem_3	388	394	PF02991	0.348
LIG_LIR_Nem_3	396	402	PF02991	0.308
LIG_LIR_Nem_3	539	543	PF02991	0.326
LIG_LIR_Nem_3	589	593	PF02991	0.336
LIG_LIR_Nem_3	609	615	PF02991	0.140
LIG_LIR_Nem_3	668	673	PF02991	0.326
LIG_LIR_Nem_3	759	765	PF02991	0.404
LIG_LIR_Nem_3	795	800	PF02991	0.299
LIG_LIR_Nem_3	944	950	PF02991	0.412
LIG_MYND_1	732	736	PF01753	0.470
LIG_MYND_1	741	745	PF01753	0.321
LIG_NRBOX	1	7	PF00104	0.659
LIG_NRBOX	134	140	PF00104	0.345
LIG_PCNA_yPIPBox_3	83	96	PF02747	0.375
LIG_Pex14_1	119	123	PF04695	0.345
LIG_Pex14_1	925	929	PF04695	0.417
LIG_Pex14_2	240	244	PF04695	0.345
LIG_PTB_Apo_2	746	753	PF02174	0.466
LIG_PTB_Apo_2	798	805	PF02174	0.342
LIG_PTB_Phospho_1	746	752	PF10480	0.496
LIG_PTB_Phospho_1	798	804	PF10480	0.343
LIG_REV1ctd_RIR_1	181	191	PF16727	0.379
LIG_SH2_CRK	290	294	PF00017	0.345
LIG_SH2_CRK	543	547	PF00017	0.461
LIG_SH2_CRK	558	562	PF00017	0.285
LIG_SH2_CRK	590	594	PF00017	0.326
LIG_SH2_CRK	704	708	PF00017	0.345
LIG_SH2_CRK	797	801	PF00017	0.306
LIG_SH2_GRB2like	26	29	PF00017	0.448
LIG_SH2_SRC	692	695	PF00017	0.326
LIG_SH2_STAP1	101	105	PF00017	0.398
LIG_SH2_STAP1	504	508	PF00017	0.237
LIG_SH2_STAP1	673	677	PF00017	0.437
LIG_SH2_STAP1	780	784	PF00017	0.408
LIG_SH2_STAP1	813	817	PF00017	0.412
LIG_SH2_STAP1	929	933	PF00017	0.443
LIG_SH2_STAT3	929	932	PF00017	0.465
LIG_SH2_STAT5	120	123	PF00017	0.345
LIG_SH2_STAT5	170	173	PF00017	0.350
LIG_SH2_STAT5	20	23	PF00017	0.559
LIG_SH2_STAT5	26	29	PF00017	0.436
LIG_SH2_STAT5	398	401	PF00017	0.433
LIG_SH2_STAT5	543	546	PF00017	0.264
LIG_SH2_STAT5	692	695	PF00017	0.326
LIG_SH2_STAT5	704	707	PF00017	0.326
LIG_SH2_STAT5	804	807	PF00017	0.356
LIG_SH2_STAT5	81	84	PF00017	0.470
LIG_SH2_STAT5	813	816	PF00017	0.371
LIG_SH3_3	119	125	PF00018	0.345
LIG_SH3_3	225	231	PF00018	0.366
LIG_SH3_3	545	551	PF00018	0.326
LIG_SH3_3	742	748	PF00018	0.326
LIG_SH3_3	8	14	PF00018	0.600
LIG_Sin3_3	348	355	PF02671	0.424
LIG_SUMO_SIM_par_1	644	650	PF11976	0.431
LIG_SUMO_SIM_par_1	865	871	PF11976	0.397
LIG_UBA3_1	561	568	PF00899	0.437
LIG_UBA3_1	829	837	PF00899	0.397
MOD_CDC14_SPxK_1	308	311	PF00782	0.424
MOD_CDK_SPK_2	457	462	PF00069	0.493
MOD_CDK_SPxK_1	305	311	PF00069	0.424
MOD_CDK_SPxxK_3	227	234	PF00069	0.431
MOD_CK1_1	154	160	PF00069	0.437
MOD_CK1_1	494	500	PF00069	0.431
MOD_CK1_1	774	780	PF00069	0.334
MOD_CK2_1	189	195	PF00069	0.345
MOD_CK2_1	31	37	PF00069	0.416
MOD_CK2_1	436	442	PF00069	0.347
MOD_CK2_1	494	500	PF00069	0.345
MOD_CK2_1	536	542	PF00069	0.345
MOD_CK2_1	599	605	PF00069	0.316
MOD_CK2_1	790	796	PF00069	0.422
MOD_CK2_1	870	876	PF00069	0.374
MOD_CK2_1	918	924	PF00069	0.546
MOD_GlcNHglycan	106	109	PF01048	0.237
MOD_GlcNHglycan	222	226	PF01048	0.401
MOD_GlcNHglycan	530	533	PF01048	0.441
MOD_GlcNHglycan	583	586	PF01048	0.326
MOD_GlcNHglycan	615	618	PF01048	0.319
MOD_GlcNHglycan	623	626	PF01048	0.305
MOD_GlcNHglycan	771	774	PF01048	0.352
MOD_GSK3_1	121	128	PF00069	0.431
MOD_GSK3_1	31	38	PF00069	0.356
MOD_GSK3_1	340	347	PF00069	0.326
MOD_GSK3_1	385	392	PF00069	0.340
MOD_GSK3_1	394	401	PF00069	0.328
MOD_GSK3_1	430	437	PF00069	0.317
MOD_GSK3_1	487	494	PF00069	0.456
MOD_GSK3_1	53	60	PF00069	0.389
MOD_GSK3_1	613	620	PF00069	0.309
MOD_GSK3_1	662	669	PF00069	0.326
MOD_GSK3_1	73	80	PF00069	0.285
MOD_GSK3_1	870	877	PF00069	0.379
MOD_N-GLC_1	154	159	PF02516	0.345
MOD_N-GLC_1	394	399	PF02516	0.345
MOD_N-GLC_1	748	753	PF02516	0.546
MOD_N-GLC_1	769	774	PF02516	0.427
MOD_N-GLC_2	344	346	PF02516	0.326
MOD_NEK2_1	151	156	PF00069	0.431
MOD_NEK2_1	196	201	PF00069	0.367
MOD_NEK2_1	260	265	PF00069	0.346
MOD_NEK2_1	41	46	PF00069	0.356
MOD_NEK2_1	481	486	PF00069	0.328
MOD_NEK2_1	487	492	PF00069	0.322
MOD_NEK2_1	53	58	PF00069	0.391
MOD_NEK2_1	662	667	PF00069	0.412
MOD_NEK2_1	719	724	PF00069	0.326
MOD_NEK2_1	73	78	PF00069	0.140
MOD_NEK2_1	785	790	PF00069	0.394
MOD_NEK2_1	818	823	PF00069	0.424
MOD_NEK2_1	835	840	PF00069	0.421
MOD_NEK2_1	962	967	PF00069	0.425
MOD_NEK2_2	523	528	PF00069	0.326
MOD_NEK2_2	887	892	PF00069	0.362
MOD_PIKK_1	756	762	PF00454	0.408
MOD_PIKK_1	763	769	PF00454	0.391
MOD_PIKK_1	818	824	PF00454	0.296
MOD_PK_1	721	727	PF00069	0.326
MOD_PKA_1	35	41	PF00069	0.392
MOD_PKA_1	678	684	PF00069	0.470
MOD_PKA_2	18	24	PF00069	0.580
MOD_PKA_2	339	345	PF00069	0.326
MOD_PKA_2	481	487	PF00069	0.345
MOD_PKB_1	338	346	PF00069	0.345
MOD_Plk_1	154	160	PF00069	0.345
MOD_Plk_1	238	244	PF00069	0.470
MOD_Plk_1	394	400	PF00069	0.345
MOD_Plk_1	541	547	PF00069	0.275
MOD_Plk_1	748	754	PF00069	0.550
MOD_Plk_1	818	824	PF00069	0.296
MOD_Plk_1	953	959	PF00069	0.505
MOD_Plk_2-3	212	218	PF00069	0.424
MOD_Plk_2-3	639	645	PF00069	0.392
MOD_Plk_4	134	140	PF00069	0.319
MOD_Plk_4	154	160	PF00069	0.163
MOD_Plk_4	239	245	PF00069	0.392
MOD_Plk_4	394	400	PF00069	0.340
MOD_Plk_4	487	493	PF00069	0.368
MOD_Plk_4	53	59	PF00069	0.472
MOD_Plk_4	557	563	PF00069	0.358
MOD_Plk_4	679	685	PF00069	0.322
MOD_Plk_4	77	83	PF00069	0.381
MOD_Plk_4	864	870	PF00069	0.380
MOD_Plk_4	91	97	PF00069	0.276
MOD_ProDKin_1	118	124	PF00069	0.385
MOD_ProDKin_1	227	233	PF00069	0.354
MOD_ProDKin_1	283	289	PF00069	0.437
MOD_ProDKin_1	305	311	PF00069	0.424
MOD_ProDKin_1	389	395	PF00069	0.409
MOD_ProDKin_1	457	463	PF00069	0.518
MOD_ProDKin_1	62	68	PF00069	0.414
MOD_SUMO_for_1	233	236	PF00179	0.354
MOD_SUMO_for_1	336	339	PF00179	0.345
MOD_SUMO_for_1	461	464	PF00179	0.368
MOD_SUMO_rev_2	644	653	PF00179	0.358
TRG_DiLeu_BaLyEn_6	1	6	PF01217	0.660
TRG_DiLeu_BaLyEn_6	846	851	PF01217	0.341
TRG_ENDOCYTIC_2	101	104	PF00928	0.345
TRG_ENDOCYTIC_2	123	126	PF00928	0.482
TRG_ENDOCYTIC_2	170	173	PF00928	0.345
TRG_ENDOCYTIC_2	543	546	PF00928	0.426
TRG_ENDOCYTIC_2	558	561	PF00928	0.217
TRG_ENDOCYTIC_2	590	593	PF00928	0.326
TRG_ENDOCYTIC_2	780	783	PF00928	0.338
TRG_ENDOCYTIC_2	797	800	PF00928	0.345
TRG_ER_diArg_1	197	200	PF00400	0.398
TRG_ER_diArg_1	2	4	PF00400	0.671
TRG_ER_diArg_1	891	893	PF00400	0.489
TRG_NES_CRM1_1	207	222	PF08389	0.424
TRG_NLS_MonoCore_2	178	183	PF00514	0.354
TRG_NLS_MonoExtN_4	177	183	PF00514	0.398
TRG_Pf-PMV_PEXEL_1	373	377	PF00026	0.427
TRG_Pf-PMV_PEXEL_1	71	75	PF00026	0.437
TRG_Pf-PMV_PEXEL_1	807	811	PF00026	0.439

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBN2	Leptomonas seymouri	81%	100%
A0A0S4IQD3	Bodo saltans	65%	100%
A0A1X0NSK4	Trypanosomatidae	68%	100%
A0A3R7KRG6	Trypanosoma rangeli	68%	100%
A0A3S7WZG4	Leishmania donovani	94%	100%
A0K321	Burkholderia cenocepacia (strain HI2424)	51%	100%
A0L103	Shewanella sp. (strain ANA-3)	51%	100%
A0M5D4	Gramella forsetii (strain KT0803)	51%	100%
A0QGN2	Mycobacterium avium (strain 104)	49%	100%
A1AF92	Escherichia coli O1:K1 / APEC	49%	100%
A1JPN3	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	48%	100%
A1KJP4	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	48%	100%
A1KV85	Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)	47%	100%
A1RFY8	Shewanella sp. (strain W3-18-1)	51%	100%
A1S965	Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)	52%	100%
A1SY74	Psychromonas ingrahamii (strain 37)	50%	100%
A1V8N7	Burkholderia mallei (strain SAVP1)	52%	100%
A2C5D4	Prochlorococcus marinus (strain NATL1A)	48%	100%
A2CDR0	Prochlorococcus marinus (strain MIT 9303)	49%	99%
A2S6F6	Burkholderia mallei (strain NCTC 10229)	52%	100%
A3D085	Shewanella baltica (strain OS155 / ATCC BAA-1091)	51%	100%
A3MQP3	Burkholderia mallei (strain NCTC 10247)	52%	100%
A3NF00	Burkholderia pseudomallei (strain 668)	52%	100%
A3P0U7	Burkholderia pseudomallei (strain 1106a)	51%	100%
A3PI15	Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)	50%	100%
A3QHI0	Shewanella loihica (strain ATCC BAA-1088 / PV-4)	50%	100%
A4HEL1	Leishmania braziliensis	84%	100%
A4I1U2	Leishmania infantum	95%	100%
A4JA69	Burkholderia vietnamiensis (strain G4 / LMG 22486)	52%	100%
A4TA90	Mycolicibacterium gilvum (strain PYR-GCK)	47%	100%
A4TIA7	Yersinia pestis (strain Pestoides F)	48%	100%
A4VRT4	Pseudomonas stutzeri (strain A1501)	50%	100%
A4WE55	Enterobacter sp. (strain 638)	49%	100%
A4WUX2	Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)	50%	100%
A4YAD8	Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)	51%	100%
A4YXQ9	Bradyrhizobium sp. (strain ORS 278)	52%	100%
A5EMM2	Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)	52%	100%
A5EYY8	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	53%	100%
A5FMT0	Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101)	51%	100%
A5GWN4	Synechococcus sp. (strain RCC307)	50%	100%
A5U3J9	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	48%	100%
A5VV25	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	48%	100%
A6TDR5	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	50%	100%
A6U8Q3	Sinorhizobium medicae (strain WSM419)	50%	100%
A6WSL1	Shewanella baltica (strain OS185)	51%	100%
A7FF21	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	48%	100%
A7MR85	Cronobacter sakazakii (strain ATCC BAA-894)	50%	100%
A7N5C4	Vibrio campbellii (strain ATCC BAA-1116)	51%	100%
A7ZR12	Escherichia coli O139:H28 (strain E24377A / ETEC)	49%	100%
A8A444	Escherichia coli O9:H4 (strain HS)	49%	100%
A8APB1	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	49%	100%
A8FZK4	Shewanella sediminis (strain HAW-EB3)	50%	100%
A8GIR9	Serratia proteamaculans (strain 568)	49%	100%
A8H7S9	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	50%	100%
A8LIH2	Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)	49%	100%
A9ACU3	Burkholderia multivorans (strain ATCC 17616 / 249)	52%	100%
A9I7K9	Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)	50%	100%
A9L330	Shewanella baltica (strain OS195)	51%	100%
A9M1P7	Neisseria meningitidis serogroup C (strain 053442)	47%	100%
A9MC11	Brucella canis (strain ATCC 23365 / NCTC 10854)	48%	100%
A9MRH2	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	49%	100%
A9N3N1	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	49%	100%
A9R4K8	Yersinia pestis bv. Antiqua (strain Angola)	48%	100%
A9WZ23	Brucella suis (strain ATCC 23445 / NCTC 10510)	48%	100%
B0TSG5	Shewanella halifaxensis (strain HAW-EB4)	49%	100%
B1IT99	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	49%	100%
B1JNS8	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	48%	100%
B1JSZ2	Burkholderia cenocepacia (strain MC0-3)	51%	100%
B1KG87	Shewanella woodyi (strain ATCC 51908 / MS32)	50%	100%
B1LDA3	Escherichia coli (strain SMS-3-5 / SECEC)	49%	100%
B1W4G3	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)	49%	100%
B1XEJ0	Escherichia coli (strain K12 / DH10B)	49%	100%
B1YQQ1	Burkholderia ambifaria (strain MC40-6)	52%	100%
B2FQE7	Stenotrophomonas maltophilia (strain K279a)	50%	100%
B2J427	Nostoc punctiforme (strain ATCC 29133 / PCC 73102)	50%	99%
B2K0Q3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	48%	100%
B2SAU5	Brucella abortus (strain S19)	48%	100%
B2T7I8	Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)	51%	99%
B2U0S0	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	49%	100%
B2UG82	Ralstonia pickettii (strain 12J)	50%	99%
B2UNH4	Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)	49%	100%
B3PP20	Rhizobium etli (strain CIAT 652)	50%	100%
B4EF26	Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)	52%	100%
B4F0N7	Proteus mirabilis (strain HI4320)	49%	100%
B4RN40	Neisseria gonorrhoeae (strain NCCP11945)	47%	100%
B4SS67	Stenotrophomonas maltophilia (strain R551-3)	50%	100%
B4T548	Salmonella newport (strain SL254)	50%	100%
B4TGX3	Salmonella heidelberg (strain SL476)	50%	100%
B5EUH1	Aliivibrio fischeri (strain MJ11)	51%	100%
B5F5H7	Salmonella agona (strain SL483)	49%	100%
B5FUG6	Salmonella dublin (strain CT_02021853)	50%	100%
B5QXI0	Salmonella enteritidis PT4 (strain P125109)	50%	100%
B5RE14	Salmonella gallinarum (strain 287/91 / NCTC 13346)	50%	100%
B5XUD5	Klebsiella pneumoniae (strain 342)	50%	100%
B5YQ95	Escherichia coli O157:H7 (strain EC4115 / EHEC)	49%	100%
B5ZQP8	Rhizobium leguminosarum bv. trifolii (strain WSM2304)	50%	100%
B6ES35	Aliivibrio salmonicida (strain LFI1238)	51%	100%
B6I736	Escherichia coli (strain SE11)	49%	100%
B7LF89	Escherichia coli (strain 55989 / EAEC)	49%	100%
B7LPB7	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	49%	100%
B7LYG7	Escherichia coli O8 (strain IAI1)	49%	100%
B7MM89	Escherichia coli O45:K1 (strain S88 / ExPEC)	49%	100%
B7MZ55	Escherichia coli O81 (strain ED1a)	49%	100%
B7N7E6	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	49%	100%
B7NHW4	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	49%	100%
B7UHV1	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	49%	100%
B8EB45	Shewanella baltica (strain OS223)	51%	100%
B8ZSN5	Mycobacterium leprae (strain Br4923)	48%	100%
B9JFK7	Agrobacterium radiobacter (strain K84 / ATCC BAA-868)	50%	100%
B9JWI2	Agrobacterium vitis (strain S4 / ATCC BAA-846)	50%	100%
B9KNU3	Cereibacter sphaeroides (strain KD131 / KCTC 12085)	50%	100%
C0PY26	Salmonella paratyphi C (strain RKS4594)	49%	100%
C0RLN1	Brucella melitensis biotype 2 (strain ATCC 23457)	48%	100%
C1APA9	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	48%	100%
C3JYR1	Pseudomonas fluorescens (strain SBW25)	51%	100%
C3LUU7	Vibrio cholerae serotype O1 (strain M66-2)	53%	100%
C5A0H5	Escherichia coli (strain K12 / MC4100 / BW2952)	49%	100%
C5BAT0	Edwardsiella ictaluri (strain 93-146)	49%	100%
C5BNY8	Teredinibacter turnerae (strain ATCC 39867 / T7901)	48%	100%
C5CRW8	Variovorax paradoxus (strain S110)	49%	100%
C6D8X1	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	49%	100%
C9ZS84	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	100%
E9AXY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
O32915	Mycobacterium leprae (strain TN)	48%	100%
O49850	Flaveria anomala	49%	94%
O49852	Flaveria trinervia	49%	94%
O49954	Solanum tuberosum	50%	94%
O80988	Arabidopsis thaliana	49%	93%
P15505	Gallus gallus	49%	97%
P23378	Homo sapiens	49%	95%
P26969	Pisum sativum	50%	92%
P33195	Escherichia coli (strain K12)	49%	100%
P49095	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	94%
P49361	Flaveria pringlei	49%	94%
P49362	Flaveria pringlei	49%	94%
P62920	Brucella abortus biovar 1 (strain 9-941)	48%	100%
P62921	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	48%	100%
P74416	Synechocystis sp. (strain PCC 6803 / Kazusa)	50%	99%
P9WN52	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	48%	100%
P9WN53	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	48%	100%
Q04PM7	Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)	50%	100%
Q055P8	Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)	50%	100%
Q07R90	Rhodopseudomonas palustris (strain BisA53)	51%	100%
Q07YC9	Shewanella frigidimarina (strain NCIMB 400)	50%	100%
Q09785	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	94%
Q0BJI1	Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)	52%	100%
Q0HEX2	Shewanella sp. (strain MR-4)	51%	100%
Q0HZ28	Shewanella sp. (strain MR-7)	51%	100%
Q0T0Z5	Shigella flexneri serotype 5b (strain 8401)	49%	100%
Q0TDU9	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	49%	100%
Q13SR6	Paraburkholderia xenovorans (strain LB400)	51%	99%
Q16AX0	Roseobacter denitrificans (strain ATCC 33942 / OCh 114)	50%	100%
Q1BRE8	Burkholderia cenocepacia (strain AU 1054)	51%	100%
Q1CB42	Yersinia pestis bv. Antiqua (strain Antiqua)	48%	100%
Q1CEZ9	Yersinia pestis bv. Antiqua (strain Nepal516)	48%	100%
Q1LHM2	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)	51%	100%
Q1MG62	Rhizobium leguminosarum bv. viciae (strain 3841)	50%	100%
Q1QCL7	Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)	47%	100%
Q1QMW0	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	51%	100%
Q1R7C8	Escherichia coli (strain UTI89 / UPEC)	49%	100%
Q21HU3	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	47%	100%
Q28L73	Jannaschia sp. (strain CCS1)	51%	100%
Q2K813	Rhizobium etli (strain CFN 42 / ATCC 51251)	51%	100%
Q2KYL7	Bordetella avium (strain 197N)	51%	100%
Q2NRF0	Sodalis glossinidius (strain morsitans)	49%	100%
Q2P021	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	49%	99%
Q2SFI6	Hahella chejuensis (strain KCTC 2396)	50%	100%
Q2STK2	Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)	52%	100%
Q2YKX9	Brucella abortus (strain 2308)	48%	100%
Q31WG4	Shigella boydii serotype 4 (strain Sb227)	49%	100%
Q32BW5	Shigella dysenteriae serotype 1 (strain Sd197)	49%	100%
Q39KU1	Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)	51%	100%
Q3AUM0	Synechococcus sp. (strain CC9902)	49%	100%
Q3BW89	Xanthomonas campestris pv. vesicatoria (strain 85-10)	50%	100%
Q3IFW1	Pseudoalteromonas translucida (strain TAC 125)	50%	100%
Q3J4D4	Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)	50%	100%
Q3JY08	Burkholderia pseudomallei (strain 1710b)	52%	100%
Q3K4Z1	Pseudomonas fluorescens (strain Pf0-1)	49%	100%
Q3K7X5	Pseudomonas fluorescens (strain Pf0-1)	50%	100%
Q3M9G1	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	50%	100%
Q3ST46	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	52%	100%
Q3YXW7	Shigella sonnei (strain Ss046)	49%	100%
Q46IC1	Prochlorococcus marinus (strain NATL2A)	48%	100%
Q46VZ5	Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)	51%	100%
Q47D81	Dechloromonas aromatica (strain RCB)	49%	100%
Q47XG2	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	50%	100%
Q486J6	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	49%	100%
Q48ME3	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	49%	100%
Q4FMV1	Pelagibacter ubique (strain HTCC1062)	47%	100%
Q4FTK9	Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)	46%	100%
Q4K416	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	49%	100%
Q4K7Q8	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	51%	100%
Q4URZ4	Xanthomonas campestris pv. campestris (strain 8004)	50%	100%
Q4ZXH2	Pseudomonas syringae pv. syringae (strain B728a)	49%	100%
Q54KM7	Dictyostelium discoideum	49%	98%
Q5DZM3	Aliivibrio fischeri (strain ATCC 700601 / ES114)	51%	100%
Q5F761	Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)	47%	100%
Q5FRY0	Gluconobacter oxydans (strain 621H)	50%	100%
Q5LDN2	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	46%	100%
Q5NZ93	Aromatoleum aromaticum (strain EbN1)	50%	100%
Q5R192	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	50%	100%
Q5YWV4	Nocardia farcinica (strain IFM 10152)	49%	100%
Q62FN1	Burkholderia mallei (strain ATCC 23344)	52%	100%
Q63PL2	Burkholderia pseudomallei (strain K96243)	52%	100%
Q64UQ7	Bacteroides fragilis (strain YCH46)	46%	100%
Q666R7	Yersinia pseudotuberculosis serotype I (strain IP32953)	48%	100%
Q6A9R8	Cutibacterium acnes (strain DSM 16379 / KPA171202)	46%	98%
Q6D974	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	49%	100%
Q6FYZ7	Bartonella quintana (strain Toulouse)	47%	100%
Q6G2F1	Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)	47%	100%
Q6LHN5	Photobacterium profundum (strain SS9)	51%	100%
Q6MPZ6	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	51%	100%
Q6N344	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	52%	98%
Q72VI8	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	50%	100%
Q73ZQ6	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	49%	100%
Q7MEH9	Vibrio vulnificus (strain YJ016)	52%	100%
Q7N199	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	49%	100%
Q7NSJ5	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	49%	100%
Q7U3Q5	Parasynechococcus marenigrum (strain WH8102)	50%	100%
Q7V411	Prochlorococcus marinus (strain MIT 9313)	49%	100%
Q7V9K4	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	45%	100%
Q7VET8	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	48%	100%
Q7W0E3	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	50%	100%
Q7W1C4	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	50%	100%
Q7WP29	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	50%	100%
Q827D7	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	49%	100%
Q83GV1	Tropheryma whipplei (strain Twist)	43%	100%
Q83IA7	Tropheryma whipplei (strain TW08/27)	43%	100%
Q83QA2	Shigella flexneri	49%	100%
Q87DR1	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	50%	98%
Q87I05	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	52%	100%
Q887L5	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	49%	100%
Q88CI9	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	49%	100%
Q88P65	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	50%	100%
Q89I86	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	53%	100%
Q8A8M0	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)	47%	100%
Q8D7G7	Vibrio vulnificus (strain CMCP6)	52%	100%
Q8DII3	Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)	51%	100%
Q8EIQ6	Shewanella oneidensis (strain MR-1)	51%	100%
Q8F937	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	50%	100%
Q8FE67	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	49%	100%
Q8FVU9	Brucella suis biovar 1 (strain 1330)	48%	100%
Q8G9M2	Rhodococcus fascians	48%	100%
Q8PBK7	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	50%	100%
Q8PN59	Xanthomonas axonopodis pv. citri (strain 306)	49%	99%
Q8UFD6	Agrobacterium fabrum (strain C58 / ATCC 33970)	49%	100%
Q8XD33	Escherichia coli O157:H7	49%	100%
Q8XU98	Ralstonia solanacearum (strain GMI1000)	50%	99%
Q8YNF9	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	49%	99%
Q8Z3X0	Salmonella typhi	49%	100%
Q8ZHI8	Yersinia pestis	48%	100%
Q8ZM76	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	49%	100%
Q91W43	Mus musculus	49%	95%
Q92Q11	Rhizobium meliloti (strain 1021)	50%	100%
Q94B78	Arabidopsis thaliana	49%	94%
Q98LT6	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	48%	100%
Q9AK84	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	49%	100%
Q9HTX7	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	48%	100%
Q9I137	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	51%	100%
Q9JT86	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	47%	100%
Q9PDJ4	Xylella fastidiosa (strain 9a5c)	50%	98%
Q9RTF5	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	51%	100%