BZIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9I6_LEIMA

TriTrypDb:

LmjF.26.0050 , LMJLV39_260005500 , LMJSD75_260005400

Length:

267

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9I6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9I6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	45	49	PF00656	0.621
CLV_NRD_NRD_1	120	122	PF00675	0.568
CLV_PCSK_KEX2_1	19	21	PF00082	0.586
CLV_PCSK_KEX2_1	250	252	PF00082	0.548
CLV_PCSK_KEX2_1	72	74	PF00082	0.580
CLV_PCSK_KEX2_1	82	84	PF00082	0.592
CLV_PCSK_PC1ET2_1	19	21	PF00082	0.586
CLV_PCSK_PC1ET2_1	250	252	PF00082	0.517
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.580
CLV_PCSK_PC1ET2_1	82	84	PF00082	0.563
CLV_PCSK_SKI1_1	110	114	PF00082	0.560
CLV_PCSK_SKI1_1	115	119	PF00082	0.561
CLV_PCSK_SKI1_1	199	203	PF00082	0.553
CLV_PCSK_SKI1_1	8	12	PF00082	0.472
CLV_Separin_Metazoa	135	139	PF03568	0.445
DEG_Nend_UBRbox_2	1	3	PF02207	0.454
DEG_SPOP_SBC_1	221	225	PF00917	0.629
DOC_MAPK_gen_1	82	92	PF00069	0.627
DOC_MAPK_MEF2A_6	208	216	PF00069	0.579
DOC_PP2B_LxvP_1	195	198	PF13499	0.500
DOC_USP7_MATH_1	148	152	PF00917	0.573
DOC_USP7_MATH_1	15	19	PF00917	0.531
DOC_USP7_MATH_1	180	184	PF00917	0.528
DOC_USP7_MATH_1	222	226	PF00917	0.625
DOC_USP7_MATH_1	30	34	PF00917	0.557
DOC_USP7_MATH_1	46	50	PF00917	0.494
DOC_USP7_UBL2_3	246	250	PF12436	0.567
DOC_USP7_UBL2_3	68	72	PF12436	0.637
DOC_USP7_UBL2_3	8	12	PF12436	0.472
DOC_WW_Pin1_4	230	235	PF00397	0.789
LIG_14-3-3_CanoR_1	115	124	PF00244	0.656
LIG_14-3-3_CanoR_1	199	204	PF00244	0.571
LIG_14-3-3_CanoR_1	20	25	PF00244	0.605
LIG_Actin_WH2_2	129	146	PF00022	0.499
LIG_FHA_1	124	130	PF00498	0.528
LIG_FHA_1	162	168	PF00498	0.572
LIG_FHA_1	231	237	PF00498	0.590
LIG_FHA_1	93	99	PF00498	0.528
LIG_FHA_2	163	169	PF00498	0.538
LIG_FHA_2	233	239	PF00498	0.650
LIG_FHA_2	250	256	PF00498	0.401
LIG_Integrin_isoDGR_2	228	230	PF01839	0.644
LIG_LIR_Gen_1	86	93	PF02991	0.528
LIG_LIR_Nem_3	86	90	PF02991	0.552
LIG_MAD2	91	99	PF02301	0.550
LIG_Pex14_2	6	10	PF04695	0.454
LIG_SH2_STAP1	74	78	PF00017	0.524
LIG_SH2_STAT5	74	77	PF00017	0.677
LIG_SH3_2	245	250	PF14604	0.640
LIG_SH3_3	188	194	PF00018	0.662
LIG_SH3_3	216	222	PF00018	0.738
LIG_SH3_3	233	239	PF00018	0.585
LIG_SH3_3	242	248	PF00018	0.667
LIG_SH3_CIN85_PxpxPR_1	194	199	PF14604	0.505
LIG_SUMO_SIM_par_1	163	171	PF11976	0.553
LIG_TRAF2_1	240	243	PF00917	0.618
LIG_WRC_WIRS_1	7	12	PF05994	0.468
LIG_WW_3	122	126	PF00397	0.486
MOD_CK1_1	176	182	PF00069	0.570
MOD_CK1_1	18	24	PF00069	0.516
MOD_CK1_1	224	230	PF00069	0.559
MOD_CK2_1	162	168	PF00069	0.624
MOD_CK2_1	249	255	PF00069	0.514
MOD_CK2_1	30	36	PF00069	0.683
MOD_CK2_1	44	50	PF00069	0.518
MOD_Cter_Amidation	70	73	PF01082	0.545
MOD_DYRK1A_RPxSP_1	230	234	PF00069	0.561
MOD_GlcNHglycan	150	153	PF01048	0.570
MOD_GlcNHglycan	175	178	PF01048	0.549
MOD_GlcNHglycan	182	185	PF01048	0.581
MOD_GlcNHglycan	32	35	PF01048	0.759
MOD_GlcNHglycan	44	47	PF01048	0.636
MOD_GSK3_1	15	22	PF00069	0.528
MOD_GSK3_1	176	183	PF00069	0.688
MOD_GSK3_1	204	211	PF00069	0.723
MOD_GSK3_1	220	227	PF00069	0.594
MOD_GSK3_1	42	49	PF00069	0.619
MOD_NEK2_1	1	6	PF00069	0.463
MOD_NEK2_1	128	133	PF00069	0.528
MOD_NEK2_1	143	148	PF00069	0.597
MOD_NEK2_1	155	160	PF00069	0.667
MOD_NEK2_1	162	167	PF00069	0.439
MOD_NEK2_1	173	178	PF00069	0.470
MOD_NEK2_1	78	83	PF00069	0.507
MOD_PIKK_1	1	7	PF00454	0.461
MOD_PK_1	20	26	PF00069	0.584
MOD_PK_1	208	214	PF00069	0.524
MOD_PKA_1	19	25	PF00069	0.599
MOD_PKA_1	249	255	PF00069	0.514
MOD_PKA_1	72	78	PF00069	0.614
MOD_PKA_2	143	149	PF00069	0.549
MOD_PKA_2	19	25	PF00069	0.642
MOD_PKA_2	72	78	PF00069	0.623
MOD_Plk_1	1	7	PF00069	0.461
MOD_Plk_1	155	161	PF00069	0.520
MOD_Plk_1	162	168	PF00069	0.448
MOD_Plk_4	162	168	PF00069	0.480
MOD_Plk_4	182	188	PF00069	0.709
MOD_ProDKin_1	230	236	PF00069	0.787
TRG_DiLeu_BaEn_1	168	173	PF01217	0.563
TRG_DiLeu_BaEn_4	242	248	PF01217	0.591
TRG_ER_diArg_1	137	140	PF00400	0.599
TRG_NLS_MonoExtC_3	248	253	PF00514	0.528
TRG_NLS_MonoExtN_4	246	253	PF00514	0.551

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCS9	Leptomonas seymouri	44%	99%
A0A3S5H7F4	Leishmania donovani	88%	100%
A4HEL3	Leishmania braziliensis	59%	100%
A4I1U4	Leishmania infantum	88%	100%
E9AXY8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%