LeishMANIAdb
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LIM zinc-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
LIM zinc-binding domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q9F0_LEIMA
TriTrypDb:
LmjF.26.0410 , LMJLV39_260009000
Length:
100

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9F0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9F0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 32 34 PF00082 0.423
CLV_PCSK_KEX2_1 46 48 PF00082 0.387
CLV_PCSK_PC1ET2_1 32 34 PF00082 0.423
CLV_PCSK_PC1ET2_1 46 48 PF00082 0.387
CLV_PCSK_SKI1_1 16 20 PF00082 0.487
DOC_MAPK_MEF2A_6 68 76 PF00069 0.458
DOC_WW_Pin1_4 61 66 PF00397 0.405
LIG_APCC_ABBAyCdc20_2 7 13 PF00400 0.415
LIG_FHA_1 39 45 PF00498 0.448
LIG_LIR_Nem_3 78 83 PF02991 0.458
LIG_NRP_CendR_1 97 100 PF00754 0.544
LIG_Pex14_1 79 83 PF04695 0.381
LIG_SH2_SRC 42 45 PF00017 0.459
LIG_SH2_STAT5 30 33 PF00017 0.485
LIG_SH2_STAT5 80 83 PF00017 0.386
MOD_CDK_SPxxK_3 61 68 PF00069 0.370
MOD_GlcNHglycan 22 25 PF01048 0.530
MOD_PK_1 47 53 PF00069 0.457
MOD_Plk_4 47 53 PF00069 0.426
MOD_ProDKin_1 61 67 PF00069 0.406
MOD_SUMO_rev_2 13 21 PF00179 0.539
TRG_ENDOCYTIC_2 83 86 PF00928 0.436
TRG_ER_diArg_1 97 100 PF00400 0.498

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IK67 Leptomonas seymouri 64% 100%
A0A3S7WZQ3 Leishmania donovani 95% 100%
A4HEP7 Leishmania braziliensis 85% 100%
A4I1X7 Leishmania infantum 95% 100%
C9ZS42 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 43% 100%
E9AY23 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5BQ50 Trypanosoma cruzi 45% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS