LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Ribonuclease inhibitor-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ribonuclease inhibitor-like protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q9E1_LEIMA
TriTrypDb:
LmjF.26.0500 * , LMJLV39_260010200 * , LMJSD75_260008800 *
Length:
429

Annotations

LeishMANIAdb annotations

Leucine-rich repeat proteins with a hydrophobic terminal helix. Unlike its distant animal relatives, this cytoplasmic sensor protein might be anchored to the membrane.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005929 cilium 4 12
GO:0042995 cell projection 2 12
GO:0043226 organelle 2 12
GO:0043227 membrane-bounded organelle 3 12
GO:0110165 cellular anatomical entity 1 12
GO:0120025 plasma membrane bounded cell projection 3 12
Previous1Next

Expansion

Sequence features

Q4Q9E1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9E1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 33 37 PF00656 0.266
CLV_NRD_NRD_1 198 200 PF00675 0.455
CLV_PCSK_KEX2_1 113 115 PF00082 0.303
CLV_PCSK_KEX2_1 198 200 PF00082 0.484
CLV_PCSK_KEX2_1 384 386 PF00082 0.553
CLV_PCSK_PC1ET2_1 113 115 PF00082 0.329
CLV_PCSK_PC1ET2_1 384 386 PF00082 0.404
CLV_PCSK_PC7_1 380 386 PF00082 0.406
CLV_PCSK_SKI1_1 198 202 PF00082 0.338
CLV_PCSK_SKI1_1 281 285 PF00082 0.492
Previous12345…12Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HUH0 Leptomonas seymouri 75% 91%
A0A0N1I317 Leptomonas seymouri 28% 100%
A0A0N1PD72 Leptomonas seymouri 25% 96%
A0A0S4IK39 Bodo saltans 26% 68%
A0A0S4JE02 Bodo saltans 23% 80%
A0A0S4JGH2 Bodo saltans 27% 100%
A0A0S4JHR1 Bodo saltans 24% 69%
A0A0S4JL85 Bodo saltans 24% 100%
A0A0S4JPV3 Bodo saltans 38% 89%
A0A0S4JXN4 Bodo saltans 25% 99%
Previous123456Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS