Trypsin-like peptidase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q9C2_LEIMA

TriTrypDb:

LmjF.26.0720 , LMJLV39_260012600 , LMJSD75_260011100

Length:

1089

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q9C2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9C2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	134	138	PF00656	0.467
CLV_C14_Caspase3-7	623	627	PF00656	0.518
CLV_C14_Caspase3-7	672	676	PF00656	0.485
CLV_C14_Caspase3-7	871	875	PF00656	0.615
CLV_NRD_NRD_1	1056	1058	PF00675	0.587
CLV_NRD_NRD_1	330	332	PF00675	0.658
CLV_NRD_NRD_1	373	375	PF00675	0.577
CLV_NRD_NRD_1	772	774	PF00675	0.715
CLV_PCSK_FUR_1	1054	1058	PF00082	0.455
CLV_PCSK_KEX2_1	1056	1058	PF00082	0.603

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICP8	Leishmania donovani	88%	100%
A4HES7	Leishmania braziliensis	67%	96%
A4I204	Leishmania infantum	88%	100%
E9AY51	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%

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