Ribosomal protein S16

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S16, putative

Species:

Leishmania major

UniProt:

Q4Q9A5_LEIMA

TriTrypDb:

LmjF.26.0890 , LMJLV39_260014400 , LMJSD75_260012800

Length:

149

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S16

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 6
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 18

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0005737	cytoplasm	2	2
GO:0015935	small ribosomal subunit	4	2
GO:0022627	cytosolic small ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0044391	ribosomal subunit	3	2
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12
GO:0005840	ribosome	5	10
GO:0016020	membrane	2	1

Expansion

Sequence features

Q4Q9A5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q9A5

Function

Biological processes
Term	Name	Level	Count
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006412	translation	4	12
GO:0006518	peptide metabolic process	4	12
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0009059	macromolecule biosynthetic process	4	12
GO:0009987	cellular process	1	12
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0019538	protein metabolic process	3	12
GO:0030490	maturation of SSU-rRNA	9	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	12
GO:0034660	ncRNA metabolic process	6	2
GO:0043043	peptide biosynthetic process	5	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043603	amide metabolic process	3	12
GO:0043604	amide biosynthetic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0044271	cellular nitrogen compound biosynthetic process	4	12
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901566	organonitrogen compound biosynthetic process	4	12
GO:1901576	organic substance biosynthetic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0003735	structural constituent of ribosome	2	12
GO:0005198	structural molecule activity	1	12
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	128	130	PF00675	0.288
CLV_PCSK_KEX2_1	128	130	PF00082	0.288
CLV_PCSK_SKI1_1	108	112	PF00082	0.297
CLV_PCSK_SKI1_1	120	124	PF00082	0.282
DOC_MAPK_gen_1	17	24	PF00069	0.488
DOC_MAPK_gen_1	51	60	PF00069	0.495
DOC_MAPK_gen_1	68	75	PF00069	0.536
DOC_MAPK_HePTP_8	61	73	PF00069	0.494
DOC_MAPK_MEF2A_6	64	73	PF00069	0.505
DOC_USP7_MATH_1	3	7	PF00917	0.643
DOC_USP7_UBL2_3	108	112	PF12436	0.488
LIG_14-3-3_CanoR_1	137	144	PF00244	0.488
LIG_eIF4E_1	118	124	PF01652	0.498
LIG_LIR_Gen_1	119	127	PF02991	0.500
LIG_LIR_Gen_1	63	74	PF02991	0.524
LIG_LIR_Nem_3	113	118	PF02991	0.498
LIG_LIR_Nem_3	119	124	PF02991	0.498
LIG_LIR_Nem_3	63	69	PF02991	0.524
LIG_NRP_CendR_1	146	149	PF00754	0.288
LIG_REV1ctd_RIR_1	96	105	PF16727	0.518
LIG_SH2_CRK	66	70	PF00017	0.593
LIG_SH2_GRB2like	102	105	PF00017	0.528
LIG_SH2_STAP1	118	122	PF00017	0.498
LIG_SUMO_SIM_anti_2	56	63	PF11976	0.518
LIG_WRC_WIRS_1	12	17	PF05994	0.382
MOD_CK1_1	139	145	PF00069	0.488
MOD_Cter_Amidation	15	18	PF01082	0.317
MOD_GlcNHglycan	138	141	PF01048	0.288
MOD_GSK3_1	56	63	PF00069	0.575
MOD_NEK2_1	144	149	PF00069	0.527
MOD_PIKK_1	79	85	PF00454	0.593
MOD_PKA_1	17	23	PF00069	0.520
MOD_PKA_2	136	142	PF00069	0.488
MOD_Plk_1	3	9	PF00069	0.612
TRG_ENDOCYTIC_2	118	121	PF00928	0.501
TRG_ENDOCYTIC_2	66	69	PF00928	0.593
TRG_ER_diArg_1	127	129	PF00400	0.488
TRG_ER_diArg_1	141	144	PF00400	0.488
TRG_ER_diArg_1	68	71	PF00400	0.498

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4ITI6	Bodo saltans	79%	100%
A0A1D8PCW6	Candida albicans (strain SC5314 / ATCC MYA-2876)	56%	100%
A0A1X0NSB5	Trypanosomatidae	82%	99%
A0A3Q8IGZ0	Leishmania donovani	100%	100%
A0A422NMY2	Trypanosoma rangeli	81%	99%
A0B6E8	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	41%	100%
A0LXM9	Gramella forsetii (strain KT0803)	30%	100%
A1BHZ6	Chlorobium phaeobacteroides (strain DSM 266)	31%	100%
A1W187	Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)	35%	100%
A2ZB00	Oryza sativa subsp. indica	53%	100%
A4FWK9	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	40%	100%
A4HEU3	Leishmania braziliensis	95%	100%
A4I218	Leishmania infantum	100%	100%
A4QBS4	Corynebacterium glutamicum (strain R)	32%	82%
A4SDC0	Chlorobium phaeovibrioides (strain DSM 265 / 1930)	30%	100%
A6UPX0	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	42%	100%
A6UW00	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	39%	100%
A6VGR2	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	40%	100%
A7H5K0	Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)	35%	100%
A8FNE5	Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)	35%	100%
B2IK87	Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB 8712)	33%	94%
B3EFY3	Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)	30%	100%
B8D6F5	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	44%	100%
C4XNQ1	Solidesulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)	33%	100%
C6A1B6	Thermococcus sibiricus (strain DSM 12597 / MM 739)	36%	100%
C9ZRY9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	100%
C9ZRZ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	70%
E9AY66	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O22647	Fritillaria agrestis	50%	100%
O29136	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	40%	100%
O59299	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	39%	100%
O94017	Candida albicans	56%	100%
P05763	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	39%	100%
P0CT64	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
P0CT65	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
P0CX51	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	100%
P0CX52	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	100%
P14131	Mus musculus	50%	100%
P16149	Lupinus polyphyllus	49%	100%
P39468	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	35%	100%
P46293	Gossypium hirsutum	50%	100%
P54024	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	42%	100%
P62249	Homo sapiens	50%	100%
P62250	Rattus norvegicus	50%	100%
P62251	Aedes aegypti	50%	100%
P95992	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	37%	100%
Q0IQF7	Oryza sativa subsp. japonica	53%	100%
Q17VT4	Helicobacter acinonychis (strain Sheeba)	32%	100%
Q22054	Caenorhabditis elegans	52%	100%
Q29201	Sus scrofa	50%	100%
Q2NFZ9	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	44%	100%
Q3B5U1	Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530)	30%	100%
Q3T0X6	Bos taurus	50%	100%
Q42340	Arabidopsis thaliana	49%	100%
Q54Q51	Dictyostelium discoideum	55%	100%
Q5HSV2	Campylobacter jejuni (strain RM1221)	35%	100%
Q5JJE2	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	39%	100%
Q6BSI7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	57%	100%
Q6FR56	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	56%	100%
Q6L293	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	40%	100%
Q6LXM5	Methanococcus maripaludis (strain S2 / LL)	40%	100%
Q759L8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	55%	100%
Q7SFJ9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	100%
Q875N2	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	56%	100%
Q876B4	Saccharomyces exiguus	54%	100%
Q8NST5	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	32%	82%
Q8PW44	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	38%	100%
Q8TT42	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	38%	100%
Q8TVB5	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	46%	100%
Q8U0E7	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	39%	100%
Q8ZYQ0	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	40%	100%
Q90YQ7	Ictalurus punctatus	50%	100%
Q95V31	Spodoptera frugiperda	51%	99%
Q96YW3	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	35%	100%
Q979K1	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	40%	100%
Q98TR7	Heteropneustes fossilis	50%	100%
Q9HL08	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	40%	100%
Q9HQJ2	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	40%	100%
Q9M8X9	Arabidopsis thaliana	47%	100%
Q9PMI3	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	35%	100%
Q9SK22	Arabidopsis thaliana	49%	100%
Q9V195	Pyrococcus abyssi (strain GE5 / Orsay)	38%	100%
Q9W237	Drosophila melanogaster	48%	100%
Q9XEK7	Syntrichia ruralis	48%	100%
Q9YB48	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	41%	99%
V5BQ45	Trypanosoma cruzi	83%	100%